Malaria immunity targets team (TARGETS)

Research in the TARGETS team is focused on a family of "sticky" proteins known as the Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1). P. falciparum is the most pathogenic malaria parasite and a major cause of morbidity and mortality among children in sub-Saharan Africa.

Our current research projects include in vitro molecular and immunological characterization of PfEMP1 proteins associated with cerebral malaria in young children.

 

 

 

 

 

The members of the TARGETS team cover a wide range of skills within malariology, immunology, molecular,  structural and cell biology. The team is involved in a number of national and international research collaborations, e.g. MAVARECA-II.

Techniques used include 3D cell culture (BBB spheroids), genetic engineering, DNA sequencing, protein expression and purification, biosensor assays, Luminex assays, flow cytometry, hybridoma techniques, real-time quantitative PCR, flow based cellular adhesion assays, manipulation and culturing of P. falciparum malaria parasites.

We welcome graduate and undergraduate students with a background in Health & Medical Sciences and Natural Sciences to do their project with the TARGETS team. If you are interested, please contact the team leader, Assoc. Prof. Yvonne Adams.

 

 

 

 

 

 

Yvonne Adams Anja Jensen
Team leader Yvonne Adams Head of team, Anja Jensen

For more information about the TARGETS team, please contact Yvonne or Anja.

Click for a list of current members of the TARGETS team.

 

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