Mecanismos de salida de parásitos intracelulares de su célula hospedera
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Mecanismos de salida de parásitos intracelulares de su célula hospedera. / Quintana, María Del Pilar; León, Sonia; Forero, María Elisa; Camacho, Marcela.
In: Acta Biologica Colombiana, Vol. 15, No. 3, 01.09.2010, p. 19-32.Research output: Contribution to journal › Review › Research › peer-review
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TY - JOUR
T1 - Mecanismos de salida de parásitos intracelulares de su célula hospedera
AU - Quintana, María Del Pilar
AU - León, Sonia
AU - Forero, María Elisa
AU - Camacho, Marcela
PY - 2010/9/1
Y1 - 2010/9/1
N2 - Some intracellular parasites inhabit intracellular compartments known as parasitophorous vacuoles. To maintain and amplify infection, infective forms of the parasite must exit from the host cell to infect new cells. During parasite egress, two main mechanisms have been proposed: lysis of the membranes of the parasitophorus vacuole and the plasma membrane of the cell host, or fusion of these two membranes providing continuity between the lumen of the parasitophorous vacuole and the extracellular compartment. In this review we present evidence supporting these models for intracellular parasites of human importance with particular emphasis on Leishmania exit.
AB - Some intracellular parasites inhabit intracellular compartments known as parasitophorous vacuoles. To maintain and amplify infection, infective forms of the parasite must exit from the host cell to infect new cells. During parasite egress, two main mechanisms have been proposed: lysis of the membranes of the parasitophorus vacuole and the plasma membrane of the cell host, or fusion of these two membranes providing continuity between the lumen of the parasitophorous vacuole and the extracellular compartment. In this review we present evidence supporting these models for intracellular parasites of human importance with particular emphasis on Leishmania exit.
KW - Exit
KW - Intracellular parasite
KW - Membrane fusion
KW - Membrane lysis
UR - http://www.scopus.com/inward/record.url?scp=82055195250&partnerID=8YFLogxK
M3 - Review
AN - SCOPUS:82055195250
VL - 15
SP - 19
EP - 32
JO - Acta Biologica Colombiana
JF - Acta Biologica Colombiana
SN - 0120-548X
IS - 3
ER -
ID: 197729416