SURFACE team

  1. Published

    Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination

    Larsen, M. D., Lopez-Perez, Mary, Dickson, E. K., Ampomah, P., Tuikue Ndam, N., Nouta, J., Koeleman, C. A. M., Ederveen, A. L. H., Mordmüller, B., Salanti, Ali, Nielsen, Morten Agertoug, Massougbodji, A., van der Schoot, C. E., Ofori, M. F., Wuhrer, M., Hviid, Lars & Vidarsson, G., 2021, In: Nature Communications. 12, 5838.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Malaria parasite evasion of classical complement pathway attack

    Larsen, M. D., Ditlev, S., Olmos, R. B., Ampomah, P., Ofori, M. F., Garred, Peter & Hviid, Lars, 2017, In: Molecular Immunology. 89, p. 159-159

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  3. Published

    Evasion of classical complement pathway activation on Plasmodium falciparum-infected erythrocytes opsonized by PfEMP1-specific IgG

    Larsen, M. D., Quintana Varon, Maria del Pilar, Ditlev, S. B., Bayarri-Olmos, R., Ofori, M. F., Hviid, Lars & Garred, Peter, 2019, In: Frontiers in Immunology. 9, 3088.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Structure-guided identification of a family of dual receptor-binding PfEMP1 that is associated with cerebral malaria

    Lennartz, F., Adams, Y., Bengtsson, A., Olsen, R. W., Turner, L., Ndam, N. T., Ecklu-Mensah, G. D., Moussiliou, A., Ofori, M. F., Gamain, B., Lusingu, J. P., Petersen, J. E. V., Wang, C. W., Nunes-Silva, S., Jespersen, J. S., Lau, C. K. Y., Theander, T. G., Lavstsen, T., Hviid, L., Higgins, M. K. & 1 others, Jensen, Anja Ramstedt, 8 Mar 2017, In: Cell Host & Microbe. 21, 3, p. 403-414 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Mapping the binding site of a cross-reactive Plasmodium falciparum PfEMP1 monoclonal antibody inhibitory of ICAM-1 binding

    Lennartz, F., Bengtsson, A., Olsen, Rebecca Wendelboe, Joergensen, L., Brown, A., Remy, L., Man, P., Forest, E., Barfod, Lea Klingenberg, Adams, Yvonne, Higgins, M. K. & Jensen, Anja Ramstedt, 2015, In: Journal of immunology (Baltimore, Md. : 1950). 195, 7, p. 3273-83 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Biomarker of Anopheles exposure in Ghanaian children with hemoglobin S and C

    Londono-Renteria, B., Seidu, Zakaria, Lamptey, H., Ofori, M. F., Hviid, Lars & Lopez-Perez, Mary, 2024, In: Acta Tropica. 249, 8 p., 107043.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    PfEMP1-specific immunoglobulin G reactivity among Beninese pregnant women with sickle cell trait

    Lopez-Perez, Mary, Viwami, F., Seidu, Zakaria, Jensen, Anja Ramstedt, Doritchamou, J., Ndam, N. T. & Hviid, Lars, 2021, In: Open Forum Infectious Diseases. 8, 12, ofab527.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Binding of human serum proteins to Plasmodium falciparum-infected erythrocytes and its association with malaria clinical presentation

    Lopez-Perez, Mary, van der Puije, W., Castberg, F. C., Ofori, M. F. & Hviid, Lars, 2020, In: Malaria Journal. 19, 1, 362.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    mSphere of Influence: Going native, or the risk of overreliance on recombinant antigens

    Lopez-Perez, Mary, 2020, In: mSphere. 5, 2, 3 p., e00224-20.

    Research output: Contribution to journalComment/debateResearchpeer-review

  10. Published

    IgG responses to the Plasmodium falciparum antigen VAR2CSA in Colombia are restricted to pregnancy and are not induced by exposure to Plasmodium vivax

    Lopez-Perez, Mary, Larsen, M. D., Bayarri-Olmos, R., Ampomah, P., Stevenson, L., Arévalo-Herrera, M., Herrera, S. & Hviid, Lars, 2018, In: Infection and Immunity. 86, 8, e00136-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Natural acquired immunity to malaria antigens among pregnant women with hemoglobin C trait

    Lopez-Perez, Mary, Viwami, F., Doritchamou, J., Ndam, N. T. & Hviid, Lars, 2022, In: American Journal of Tropical Medicine and Hygiene. 106, 3, p. 853–856

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Cytokine response to pregnancy-associated recrudescence of Plasmodium berghei infection in mice with pre-existing immunity to malaria

    Megnekou, R., Staalsø, Trine & Hviid, Lars, 1 Nov 2013, In: Malaria Journal. 12, 1, p. 387

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Etiology of placental Plasmodium falciparum malaria in African women

    Ofori, M. F., Lamptey, H., Dickson, E. K., Kyei-Baafour, E. & Hviid, Lars, 2018, In: The Journal of Infectious Diseases. 218, 2, p. 277-281 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Profiling the Plasmodium falciparum erythrocyte membrane protein 1-specific immununoglobulin G response among Ghanaian children with hemoglobin S and C

    Oleinikov, A. V., Seidu, Zakaria, Oleinikov, I. V., Tetteh, M., Lamptey, H., Ofori, M. F., Hviid, Lars & Lopez-Perez, Mary, 2024, In: The Journal of Infectious Diseases. 229, 1, p. 203-213

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Natural and vaccine-induced acquisition of cross-reactive IgG inhibiting ICAM-1-specific binding of a Plasmodium falciparum PfEMP1 subtype associated specifically with cerebral malaria

    Olsen, Rebecca Wendelboe, Ecklu-Mensah, G., Bengtsson, A., Ofori, M. F., Lusingu, J. P. A., Castberg, F. C., Hviid, Lars, Adams, Yvonne & Jensen, Anja Ramstedt, 2018, In: Infection and Immunity. 86, 4, 17 p., e00622-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Acquisition of IgG to ICAM-1-Binding DBLβ Domains in the Plasmodium falciparum erythrocyte membrane protein 1 antigen family varies between Groups A, B, and C

    Olsen, Rebecca Wendelboe, Ecklu-Mensah, G., Bengtsson, A., Ofori, M. F., Kusi, K. A., Koram, K. A., Hviid, Lars, Adams, Yvonne & Jensen, Anja Ramstedt, 2019, In: Infection and Immunity. 87, 10, e00224-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Kinetics of antibody responses to PfRH5-complex antigens in Ghanaian children with Plasmodium falciparum malaria

    Partey, Frederica Dedo, Castberg, F. C., Sarbah, E. W., Silk, S. E., Awandare, G. A., Draper, S. J., Opoku, N., Kweku, M., Ofori, M. F., Hviid, Lars & Barfod, Lea Klingenberg, 2018, In: PLOS ONE. 13, 6, 14 p., e0198371.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions

    Payne, R. O., Silk, S. E., Elias, S. C., Miura, K., Diouf, A., Galaway, F., de Graaf, H., Brendish, N. J., Poulton, I. D., Griffiths, O. J., Edwards, N. J., Jin, J., Labbé, G. M., Alanine, D. G., Siani, L., Di Marco, S., Roberts, R., Green, N., Berrie, E., Ishizuka, A. S. & 22 others, Nielsen, C. M., Bardelli, M., Partey, Frederica Dedo, Ofori, M. F., Barfod, Lea Klingenberg, Wambua, J., Murungi, L. M., Osier, F. H., Biswas, S., McCarthy, J. S., Minassian, A. M., Ashfield, R., Viebig, N. K., Nugent, F. L., Douglas, A. D., Vekemans, J., Wright, G. J., Faust, S. N., Hill, A. V., Long, C. A., Lawrie, A. M. & Draper, S. J., Nov 2017, In: JCI insight. 2, 21, 19 p., e96381.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Immunoglobulin M: restrainer of inflammation and mediator of immune evasion by Plasmodium falciparum malaria

    Pleass, R. J., Moore, S. C., Stevenson, L. & Hviid, Lars, Feb 2016, In: Trends in Parasitology. 32, 2, p. 108-119 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  20. Published

    The density of knobs on Plasmodium falciparum-infected erythrocytes depends on developmental age and varies among isolates

    Quadt, K. A., Barfod, Lea Klingenberg, Andersen, D., Bruun, J., Gyan, B., Hassenkam, Tue, Ofori, M. F. & Hviid, Lars, 2012, In: P L o S One. 7, 9, p. e45658

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Exit mechanisms of intracellular parasites from their host cells,Mecanismos de salida de parásitos intracelulares de su célula hospedera

    Quintana Varon, Maria del Pilar, León, S., Forero, M. E. & Camacho, M., 2010, In: Acta Biologica Colombiana.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Measuring naturally acquired phagocytosis-inducing antibodies to Plasmodium falciparum parasites by a flow cytometry-based assay

    Quintana Varon, Maria del Pilar, Anabire, N. G. & Hviid, Lars, 6 Aug 2020, In: Journal of visualized experiments : JoVE. 162, e61538.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Comprehensive analysis of Fc-mediated IgM binding to the Plasmodium falciparum erythrocyte membrane protein 1 family in three parasite clones

    Quintana Varon, Maria del Pilar, Ecklu-Mensah, G., Tcherniuk, S. O., Ditlev, S. B., Oleinikov, A. V., Hviid, Lars & Lopez-Perez, Mary, 2019, In: Scientific Reports. 9, 1, 11 p., 6050.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Endemic Burkitt lymphoma - an aggressive childhood cancer linked to Plasmodium falciparum exposure, but not to exposure to other malaria parasites

    Quintana Varon, Maria del Pilar, Smith-Togobo, C., Moormann, A. & Hviid, Lars, 2020, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 128, 2, p. 129-135

    Research output: Contribution to journalReviewResearchpeer-review

  25. Published

    mSphere of Influence: Structural insights into the molecular mechanism underlying placental malaria

    Quintana Varon, Maria del Pilar, 2021, In: mSphere. 6, 3, 4 p., e00391-21 .

    Research output: Contribution to journalComment/debateResearchpeer-review

  26. Published

    Mecanismos de salida de parásitos intracelulares de su célula hospedera

    Quintana Varon, Maria del Pilar, León, S., Forero, M. E. & Camacho, M., 1 Sep 2010, In: Acta Biologica Colombiana. 15, 3, p. 19-32 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  27. Published
  28. Published

    Malaria

    Riley, E. M., Hviid, Lars & Theander, Thor Grundtvig, 22 Oct 2013, Parasitic Infections and the Immune System. Elsevier Science Inc., p. 119-143 25 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  29. Published

    Malaria in pregnancy complications in Southern Venezuela

    Romero, M., Leiba, E., Carrión-Nessi, F. S., Freitas-De Nobrega, D. C., Kaid-Bay, S., Gamardo, Á. F., Chavero, M., Figuera, L., Camejo-Ávila, N. A., Marcano, M. V., Lopez-Perez, Mary & Forero-Peña, D. A., 2021, In: Malaria Journal. 20, 1, 186.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Clinical and laboratory characteristics of children with sickle cell disease on hydroxyurea treated with artemether-lumefantrine for acute uncomplicated malaria

    Segbefia, C., Amponsah, S. K., Afrane, A. K. A., Nyarko, M. Y., Brew, Y., Salifu, N., Ahorhorlu, S. Y., Sulley, A. M., Hviid, Lars, Ofori, M. F. & Adjei, G. O., 2023, In: Frontiers in Medicine. 10, p. 1291330

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Plasmodium falciparum infection and naturally acquired immunity to malaria antigens among Ghanaian children in northern Ghana

    Seidu, Zakaria, Lamptey, H., Lopez-Perez, Mary, Whittle, N. O., Oppong, S. K., Kyei-Baafour, E., Pobee, A. N. A., Adjei, G. O., Hviid, Lars & Ofori, M. F., 2023, In: Parasite Epidemiology and Control. 22, p. e00317

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites

    Sleebs, B. E., Lopaticki, S., Marapana, D. S., O'Neill, M. T., Rajasekaran, P., Gazdik, M., Günther, S., Whitehead, L. W., Lowes, K. N., Barfod, Lea Klingenberg, Hviid, Lars, Shaw, P. J., Hodder, A. N., Smith, B. J., Cowman, A. F. & Boddey, J. A., 2014, In: P L o S Biology. 12, 7, p. e1001897

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    High frequencies of tumor-infiltrating and circulating γδ T cells in endemic Burkitt lymphoma patients

    Smith-Togobo, C., Quintana Varon, Maria del Pilar, Ofori, M. F. & Hviid, Lars, 2019, In: American Journal of Tropical Medicine and Hygiene. 101, S5, p. 563-563 1830.

    Research output: Contribution to journalConference abstract in journalResearch

  34. Published

    Reliable cell and tissue morphology-based diagnosis of endemic Burkitt lymphoma in resource-constrained settings in Ghana

    Smith-Togobo, C., Pedersen, Mette Ølgod, Jensen, S. G., Duduyemi, B., Gyasi, R. K., Ofori, M. F., Paintsil, V., Renner, L., Nørgaard, P. & Hviid, Lars, 2019, In: BMC Cancer. 19, 7 p., 1270.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Human monoclonal IgG selection of Plasmodium falciparum for the expression of placental malaria-specific variant surface antigens

    Soerli, J., Barfod, Lea Klingenberg, Lavstsen, Thomas, Bernasconi, N. L., Lanzavecchia, A. & Hviid, Lars, 2009, In: Parasite Immunology. 31, 6, p. 341-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Investigating the function of Fc -specific binding of IgM to Plasmodium falciparum erythrocyte membrane protein 1 mediating erythrocyte rosetting

    Stevenson, L., Huda, P., Jeppesen, A., Laursen, E. T. F., Rowe, J. A., Craig, A., Streicher, W., Barfod, Lea Klingenberg & Hviid, Lars, Jun 2015, In: Cellular Microbiology. 17, 6, p. 819-31 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    α2-macroglobulin can crosslink multiple Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) molecules and may facilitate adhesion of parasitized erythrocytes

    Stevenson, L., Laursen, E., Cowan, G. J., Bandoh, B., Barfod, Lea Klingenberg, Cavanagh, D. R., Andersen, G. R. & Hviid, Lars, Jul 2015, In: P L o S Pathogens. 11, 7, p. 1-19 19 p., e1005022.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    The Malaria Pigment Hemozoin Comprises at Most Four Different Isomer Units in Two Crystalline Models: Chiral as Based on a Biochemical Hypothesis or Centrosymmetric Made of Enantiomorphous Sectors

    Straasø, T., Marom, N., Solomonov, I., Barfod, Lea Klingenberg, Burghammer, M., Feidenhans'l, Robert Krarup, Als-Nielsen, Jens & Leiserowitz, L., 17 Mar 2014, In: Crystal Growth & Design. 14, 4, p. 1543-1554 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Plasmodium falciparum-infected erythrocyte knob density is linked to the PfEMP1 variant expressed

    Subramani, R., Quadt, K., Jeppesen, A. E., Hempel, C., Petersen, J. E. V., Hassenkam, Tue, Hviid, Lars & Barfod, Lea Klingenberg, 2015, In: mBio. 6, 5, 7 p., e01456-15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    ICAM-1-binding Plasmodium falciparum erythrocyte membrane protein 1 variants elicits opsonic-phagocytosis IgG responses in Beninese children

    Suurbaar, Jennifer, Moussiliou, A., Tahar, R., Olsen, Rebecca Wendelboe, Adams, Yvonne, Dalgaard, Nanna, Baafour, E. K., Adukpo, S., Hviid, Lars, Kusi, K. A., Alao, J., Ofori, M. F., Ndam, N. T. & Jensen, Anja Ramstedt, 2022, In: Scientific Reports. 12, 12994.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Acquisition and decay of IgM and IgG responses to merozoite antigens after Plasmodium falciparum malaria in Ghanaian children

    Walker, Melanie Rose, Knudsen, Anne Schlitterlau, Partey, Frederica Dedo, Bassi, Maria Rosaria, Frank, A. M., Castberg, F. C., Sarbah, E. W., Ofori, M. F., Hviid, Lars & Barfod, Lea Klingenberg, 2020, In: PLoS ONE. 15, 12, p. e0243943

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Rifins, rosetting, and red blood cells

    Wang, Christian William & Hviid, Lars, Jul 2015, In: Trends in Parasitology. 31, 7, p. 285-6 2 p.

    Research output: Contribution to journalJournal articleCommissionedpeer-review

  43. Published

    Prevalence and dynamic changes in lung ultrasound findings among adults with uncomplicated malaria and controls in the Amazon basin, Brazil

    Wegener, A., Holm, A. E., Gomes, L. C., Lima, K. O., Matos, L. O., Vieira, I. V. M., Kaagaard, M. D., de Souza, R. M., Hviid, Lars, Guimarães Lacerda, M. V., Vestergaard, L. S., Farias Marinho, C. R., Platz, E., Biering-Sørensen, Tor, Silvestre, O. M. & Brainin, P., 2022, In: American Journal of Tropical Medicine and Hygiene. 106, 6, p. 1637-1645 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Immune selection and within-host competition can structure the repertoire of variant surface antigens in Plasmodium falciparum -a mathematical model

    van Noort, S. P., Nunes, M. C., Weedall, G. D., Hviid, Lars & Gomes, M. G. M., 2010, In: PLoS ONE. 5, 3, p. e9778

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    In vitro selection for adhesion of Plasmodium falciparum-infected erythrocytes to ABO antigens does not affect PfEMP1 and RIFIN expression

    van der Puije, W., Wang, Christian William, Sudharson, S., Hempel, C., Olsen, Rebecca Wendelboe, Dalgaard, Nanna, Ofori, M. F., Hviid, Lars, Kurtzhals, Jørgen & Staalsø, Trine, 2020, In: Scientific Reports. 10, 1, p. 12871 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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