SURFACE team

  1. Published

    α2-macroglobulin can crosslink multiple Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) molecules and may facilitate adhesion of parasitized erythrocytes

    Stevenson, L., Laursen, E., Cowan, G. J., Bandoh, B., Barfod, Lea Klingenberg, Cavanagh, D. R., Andersen, G. R. & Hviid, Lars, Jul 2015, In: P L o S Pathogens. 11, 7, p. 1-19 19 p., e1005022.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    mSphere of Influence: Going native, or the risk of overreliance on recombinant antigens

    Lopez-Perez, Mary, 2020, In: mSphere. 5, 2, 3 p., e00224-20.

    Research output: Contribution to journalComment/debateResearchpeer-review

  3. Published

    mSphere of Influence: Structural insights into the molecular mechanism underlying placental malaria

    Quintana Varon, Maria del Pilar, 2021, In: mSphere. 6, 3, 4 p., e00391-21 .

    Research output: Contribution to journalComment/debateResearchpeer-review

  4. Published

    Trying to remember: immunological B cell memory to malaria

    Hviid, Lars, Barfod, Lea Klingenberg & Fowkes, F. J. I., Mar 2015, In: Trends in Parasitology. 31, 3, p. 89-94 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    Transfected HEK293 Cells Expressing Functional Recombinant Intercellular Adhesion Molecule 1 (ICAM-1) - A Receptor Associated with Severe Plasmodium falciparum Malaria

    Bengtsson, A., Joergensen, L., Barbati, Z. R., Craig, A., Hviid, Lars & Jensen, Anja Ramstedt, 2013, In: PLOS ONE. 8, 7, p. e69999

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The role of Plasmodium falciparum variant surface antigens in protective immunity and vaccine development

    Hviid, Lars, 2010, In: Human Vaccines. 6, 1, p. 84-89 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The rapid and spontaneous postpartum clearance of Plasmodium falciparum is related to expulsion of the placenta

    Anabire, Nsoh Godwin, Quintana Varon, Maria del Pilar, Ofori, M. F. & Hviid, Lars, 2023, In: The Journal of Infectious Diseases. 228, 2, p. 196-201 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The kinetics of antibody binding to Plasmodium falciparum VAR2CSA PfEMP1 antigen and modelling of PfEMP1 antigen packing on the membrane knobs

    Joergensen, L. M., Salanti, Ali, Dobrilovic, T., Barfod, Lea Klingenberg, Hassenkam, Tue, Theander, Thor Grundtvig, Hviid, Lars & Arnot, D. E., 2010, In: Malaria Journal. 9, 1, p. 100

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The density of knobs on Plasmodium falciparum-infected erythrocytes depends on developmental age and varies among isolates

    Quadt, K. A., Barfod, Lea Klingenberg, Andersen, D., Bruun, J., Gyan, B., Hassenkam, Tue, Ofori, M. F. & Hviid, Lars, 2012, In: P L o S One. 7, 9, p. e45658

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The case for PfEMP1-based vaccines to protect pregnant women against Plasmodium falciparum malaria

    Hviid, Lars, 2011, In: Expert Review of Vaccines. 10, 10, p. 1405-14 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner

    Agerbæk, Mette Ørskov, Bang-Christensen, S. R., Yang, M., Clausen, Thomas Mandel, Pereira, M. A., Sharma, S., Ditlev, S. B., Nielsen, Morten Agertoug, Choudhary, Swati, Gustavsson, Tobias, Sorensen, P. H., Meyer, T., Propper, D., Shamash, J., Theander, Thor Grundtvig, Aicher, A., Daugaard, M., Heeschen, C. & Salanti, Ali, 2018, In: Nature Communications. 9, 1, 13 p., 3279.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The Malaria Pigment Hemozoin Comprises at Most Four Different Isomer Units in Two Crystalline Models: Chiral as Based on a Biochemical Hypothesis or Centrosymmetric Made of Enantiomorphous Sectors

    Straasø, T., Marom, N., Solomonov, I., Barfod, Lea Klingenberg, Burghammer, M., Feidenhans'l, Robert Krarup, Als-Nielsen, Jens & Leiserowitz, L., 17 Mar 2014, In: Crystal Growth & Design. 14, 4, p. 1543-1554 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Suitability of IgG responses to multiple Plasmodium falciparum antigens as markers of transmission intensity and pattern

    Kyei-Baafour, E., Oppong, M., Kusi, K. A., Frempong, A. F., Aculley, B., Arthur, F. K. N., Tiendrebeogo, R. W., Singh, S. K., Theisen, Michael, Kweku, M., Adu, B., Hviid, Lars & Ofori, M. F., 2021, In: PLoS ONE. 16, 4, e0249936.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Structure-guided identification of a family of dual receptor-binding PfEMP1 that is associated with cerebral malaria

    Lennartz, F., Adams, Y., Bengtsson, A., Olsen, R. W., Turner, L., Ndam, N. T., Ecklu-Mensah, G. D., Moussiliou, A., Ofori, M. F., Gamain, B., Lusingu, J. P., Petersen, J. E. V., Wang, C. W., Nunes-Silva, S., Jespersen, J. S., Lau, C. K. Y., Theander, T. G., Lavstsen, T., Hviid, L., Higgins, M. K. & 1 others, Jensen, Anja Ramstedt, 8 Mar 2017, In: Cell Host & Microbe. 21, 3, p. 403-414 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Seroprevalence of viral and bacterial pathogens among malaria patients in an endemic area of southern Venezuela

    Forero-Peña, D. A., Carrión-Nessi, F. S., Lopez-Perez, Mary, Sandoval-de Mora, M., Amaya, I. D., Gamardo, Á. F., Chavero, M., Figuera, L., Marcano, M. V., Camejo-Ávila, N. A., Hidalgo, M., Arenas, C. J., Arévalo-Herrera, M. & Herrera, S., 2023, In: Infectious Diseases of Poverty. 12, 33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Rifins, rosetting, and red blood cells

    Wang, Christian William & Hviid, Lars, Jul 2015, In: Trends in Parasitology. 31, 7, p. 285-6 2 p.

    Research output: Contribution to journalJournal articleCommissionedpeer-review

  17. Published

    Reliable cell and tissue morphology-based diagnosis of endemic Burkitt lymphoma in resource-constrained settings in Ghana

    Smith-Togobo, C., Pedersen, Mette Ølgod, Jensen, S. G., Duduyemi, B., Gyasi, R. K., Ofori, M. F., Paintsil, V., Renner, L., Nørgaard, P. & Hviid, Lars, 2019, In: BMC Cancer. 19, 7 p., 1270.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Profiling the Plasmodium falciparum erythrocyte membrane protein 1-specific immununoglobulin G response among Ghanaian children with hemoglobin S and C

    Oleinikov, A. V., Seidu, Zakaria, Oleinikov, I. V., Tetteh, M., Lamptey, H., Ofori, M. F., Hviid, Lars & Lopez-Perez, Mary, 2024, In: The Journal of Infectious Diseases. 229, 1, p. 203-213

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Prevalence and dynamic changes in lung ultrasound findings among adults with uncomplicated malaria and controls in the Amazon basin, Brazil

    Wegener, A., Holm, A. E., Gomes, L. C., Lima, K. O., Matos, L. O., Vieira, I. V. M., Kaagaard, M. D., de Souza, R. M., Hviid, Lars, Guimarães Lacerda, M. V., Vestergaard, L. S., Farias Marinho, C. R., Platz, E., Biering-Sørensen, Tor, Silvestre, O. M. & Brainin, P., 2022, In: American Journal of Tropical Medicine and Hygiene. 106, 6, p. 1637-1645 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Precipitated malaria: It never rains but it pours

    Hviid, Lars, 2020, In: Trends in Parasitology. 36, 9, p. 721-723 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  21. Published

    Plasmodium falciparum Rosetting Epitopes Converge in the SD3-Loop of PfEMP1-DBL1α

    Angeletti, D., Albrecht, L., Blomqvist, K., Quintana Varon, Maria del Pilar, Akhter, T., Bächle, S. M., Sawyer, A., Sandalova, T., Achour, A., Wahlgren, M. & Moll, K., 5 Dec 2012, In: PLOS ONE. 7, 12, e50758.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Plasmodium falciparum Expressing Domain Cassette 5 Type PfEMP1 (DC5-PfEMP1) Bind PECAM1

    Berger, S. S., Turner, Louise, Wang, Christian William, Petersen, J. E. V., Kraft, M., Lusingu, J. P. A., Mmbando, B., Marquard, A. M., Bengtsson, D. B. A. C., Hviid, Lars, Nielsen, Morten Agertoug, Theander, Thor Grundtvig & Lavstsen, Thomas, 2013, In: PloS one. 8, 7, p. e69117

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    PfEMP1-specific immunoglobulin G reactivity among Beninese pregnant women with sickle cell trait

    Lopez-Perez, Mary, Viwami, F., Seidu, Zakaria, Jensen, Anja Ramstedt, Doritchamou, J., Ndam, N. T. & Hviid, Lars, 2021, In: Open Forum Infectious Diseases. 8, 12, ofab527.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    PfEMP1 – a parasite protein family of key importance in Plasmodium falciparum malaria immunity and pathogenesis

    Hviid, Lars & Jensen, Anja Ramstedt, Apr 2015, Advances in Parasitology. Rollinson, D. & Stothard, J. R. (eds.). Vol. 88. p. 51-84 34 p. (Advances in Parasitology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  25. E-pub ahead of print

    PfEMP1 and var genes – Still of key importance in Plasmodium falciparum malaria pathogenesis and immunity

    Hviid, Lars, Jensen, Anja Ramstedt & Deitsch, K. W., 2024, (E-pub ahead of print) Advances in Parasitology. Academic Press, 51 p. (Advances in Parasitology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  26. Published

    Orm i toilettet

    Hviid, Lars, Møller-Bisgaard, S. & Kurtzhals, Jørgen, 15 Feb 2016, In: Ugeskrift for Laeger. 178, 7, 1 p., V67428.

    Research output: Contribution to journalJournal articleCommunication

  27. Published

    Of mice and women: rodent models of placental malaria

    Hviid, Lars, Marinho, C. R. F., Staalsø, Trine & Penha-Gonçalves, C., 2010, In: Trends in Parasitology. 26, 8, p. 412-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    No sweet deal: the antibody-mediated immune response to malaria

    Hviid, Lars, Lopez-Perez, Mary, Larsen, M. D. & Vidarsson, G., 2022, In: Trends in Parasitology. 38, 6, p. 428-434

    Research output: Contribution to journalReviewResearchpeer-review

  29. Published

    Natural and vaccine-induced acquisition of cross-reactive IgG inhibiting ICAM-1-specific binding of a Plasmodium falciparum PfEMP1 subtype associated specifically with cerebral malaria

    Olsen, Rebecca Wendelboe, Ecklu-Mensah, G., Bengtsson, A., Ofori, M. F., Lusingu, J. P. A., Castberg, F. C., Hviid, Lars, Adams, Yvonne & Jensen, Anja Ramstedt, 2018, In: Infection and Immunity. 86, 4, 17 p., e00622-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Natural acquired immunity to malaria antigens among pregnant women with hemoglobin C trait

    Lopez-Perez, Mary, Viwami, F., Doritchamou, J., Ndam, N. T. & Hviid, Lars, 2022, In: American Journal of Tropical Medicine and Hygiene. 106, 3, p. 853–856

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Multiple Plasmodium falciparum erythrocyte membrane protein 1 variants per genome can bind IgM via its Fc fragment Fcμ

    Jeppesen, A., Ditlev, S. B., Soroka, V., Stevenson, E. K., Turner, Louise, Dzikowski, R., Hviid, Lars & Barfod, Lea Klingenberg, 2015, In: Infection and Immunity. 83, 10, p. 3972-81 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Modeling malaria infection and immunity against variant surface antigens in Príncipe island, West Africa

    Bandeiras, C., Trovoada, M. J., Gonçalves, L. A., Marinho, C. R. F., Turner, Louise, Hviid, Lars, Penha-Gonçalves, C. & Gomes, M. G. M., 2014, In: PloS one. 9, 2, p. e88110

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Mecanismos de salida de parásitos intracelulares de su célula hospedera

    Quintana Varon, Maria del Pilar, León, S., Forero, M. E. & Camacho, M., 1 Sep 2010, In: Acta Biologica Colombiana. 15, 3, p. 19-32 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  34. Published

    Measuring naturally acquired phagocytosis-inducing antibodies to Plasmodium falciparum parasites by a flow cytometry-based assay

    Quintana Varon, Maria del Pilar, Anabire, N. G. & Hviid, Lars, 6 Aug 2020, In: Journal of visualized experiments : JoVE. 162, e61538.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Mapping the binding site of a cross-reactive Plasmodium falciparum PfEMP1 monoclonal antibody inhibitory of ICAM-1 binding

    Lennartz, F., Bengtsson, A., Olsen, Rebecca Wendelboe, Joergensen, L., Brown, A., Remy, L., Man, P., Forest, E., Barfod, Lea Klingenberg, Adams, Yvonne, Higgins, M. K. & Jensen, Anja Ramstedt, 2015, In: Journal of immunology (Baltimore, Md. : 1950). 195, 7, p. 3273-83 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Malaria vaccines: immunity, models and monoclonal antibodies

    Hviid, Lars & Barfod, Lea Klingenberg, 2008, In: Trends in Parasitology. 24, 9, p. 392-395 3 p.

    Research output: Contribution to journalReviewResearchpeer-review

  37. Published

    Malaria parasite evasion of classical complement pathway attack

    Larsen, M. D., Ditlev, S., Olmos, R. B., Ampomah, P., Ofori, M. F., Garred, Peter & Hviid, Lars, 2017, In: Molecular Immunology. 89, p. 159-159

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  38. Published

    Malaria in pregnancy complications in Southern Venezuela

    Romero, M., Leiba, E., Carrión-Nessi, F. S., Freitas-De Nobrega, D. C., Kaid-Bay, S., Gamardo, Á. F., Chavero, M., Figuera, L., Camejo-Ávila, N. A., Marcano, M. V., Lopez-Perez, Mary & Forero-Peña, D. A., 2021, In: Malaria Journal. 20, 1, 186.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Malaria immunology: Targeting the surface of infected erythrocytes

    Jensen, Anja Ramstedt (ed.) & Hviid, Lars (ed.), 2022, Humana Press. 796 p. (Methods in Molecular Biology, Vol. 2470).

    Research output: Book/ReportBookResearchpeer-review

  40. Published

    Malaria causes long-term effects on markers of iron status in children: a critical assessment of existing clinical and epidemiological tools

    Castberg, F. C., Sarbah, E. W., Koram, K. A., Opoku, N., Ofori, M. F., Styrishave, Bjarne, Hviid, Lars & Kurtzhals, Jørgen, 11 Dec 2018, In: Malaria Journal. 17, 1, 464.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Malaria

    Riley, E. M., Hviid, Lars & Theander, Thor Grundtvig, 22 Oct 2013, Parasitic Infections and the Immune System. Elsevier Science Inc., p. 119-143 25 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  42. Published

    Looking for needles in the Plasmodial haystack

    Hviid, Lars, 2019, In: mSphere. 4, 2, 3 p., e00146-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Kinetics of antibody responses to PfRH5-complex antigens in Ghanaian children with Plasmodium falciparum malaria

    Partey, Frederica Dedo, Castberg, F. C., Sarbah, E. W., Silk, S. E., Awandare, G. A., Draper, S. J., Opoku, N., Kweku, M., Ofori, M. F., Hviid, Lars & Barfod, Lea Klingenberg, 2018, In: PLOS ONE. 13, 6, 14 p., e0198371.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Kinetics of B Cell responses to Plasmodium falciparum erythrocyte membrane protein 1 in Ghanaian women naturally exposed to malaria parasites

    Ampomah, P., Stevenson, L., Ofori, M. F., Barfod, Lea Klingenberg & Hviid, Lars, 1 Jun 2014, In: Journal of Immunology. 192, 11, p. 5236-44 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Investigating the function of Fc -specific binding of IgM to Plasmodium falciparum erythrocyte membrane protein 1 mediating erythrocyte rosetting

    Stevenson, L., Huda, P., Jeppesen, A., Laursen, E. T. F., Rowe, J. A., Craig, A., Streicher, W., Barfod, Lea Klingenberg & Hviid, Lars, Jun 2015, In: Cellular Microbiology. 17, 6, p. 819-31 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Insights into deregulated TNF and IL-10 production in malaria: implications for understanding severe malarial anaemia

    Boeuf, P. S., Loizon, S., Awandare, G. A., Tetteh, J. K., Addae, M. M., Adjei, G. O., Goka, B., Kurtzhals, Jørgen, Puijalon, O., Hviid, Lars, Akanmori, B. D. & Behr, C., 2012, In: Malaria Journal. 11, 1, p. 253

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites

    Sleebs, B. E., Lopaticki, S., Marapana, D. S., O'Neill, M. T., Rajasekaran, P., Gazdik, M., Günther, S., Whitehead, L. W., Lowes, K. N., Barfod, Lea Klingenberg, Hviid, Lars, Shaw, P. J., Hodder, A. N., Smith, B. J., Cowman, A. F. & Boddey, J. A., 2014, In: P L o S Biology. 12, 7, p. e1001897

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Influence of α2-macroglobulin, anti-parasite IgM and ABO blood group on rosetting in Plasmodium falciparum clinical isolates and their associations with disease severity in a Ghanaian population

    Bandoh, B., Kyei-Baafour, E., Aculley, B., van der Puije, W., Tornyigah, B., Akyea-Mensah, K., Hviid, Lars, Ngala, R. A., Frempong, M. T. & Ofori, M. F., 2022, In: Journal of Blood Medicine. 13, p. 151-164 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Increased Plasmodium chabaudi malaria mortality in mice with nutritional iron deficiency can be reduced by short-term adjunctive iron supplementation

    Castberg, F. C., Maretty, L., Staalsø, Trine, Hempel, C., Clasen-Linde, E., Hviid, Lars & Kurtzhals, Jørgen, 16 Jan 2018, In: Malaria Journal. 17, 1, 12 p., 34.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Immunoglobulin M: restrainer of inflammation and mediator of immune evasion by Plasmodium falciparum malaria

    Pleass, R. J., Moore, S. C., Stevenson, L. & Hviid, Lars, Feb 2016, In: Trends in Parasitology. 32, 2, p. 108-119 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

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