Centre for Medical Parasitology

  1. 1998
  2. Published

    Humoral and cellular immune responses to synthetic peptides of the Leishmania donovani kinetoplastid membrane protein-11

    Jensen, Anja Ramstedt, Gasim, S., Ismail, A., Gaafar, A., Kurtzhals, Jørgen, Kemp, M., El Hassan, A. M., Kharazmi, A. & Theander, Thor Grundtvig, 1998, In: Scandinavian Journal of Immunology. 48, 1, p. 103-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Identification of an erythrocyte binding peptide from the erythrocyte binding antigen, EBA-175, which blocks parasite multiplication and induces peptide-blocking antibodies

    Jakobsen, P. H., Heegaard, P. M., Koch, C., Wasniowska, K., Lemnge, M. M., Jensen, J. B. & Sim, B. K., 1998, In: Infection and Immunity. 66, 9, p. 4203-4207 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Increased eosinophil activity in acute Plasmodium falciparum infection - association with cerebral malaria

    Kurtzhals, Jørgen, Reimert, C. M., Tette, E., Dunyo, S. K., Koram, K. A., Akanmori, B. D., Nkrumah, F. K. & Hviid, Lars, 1998, In: Clinical and Experimental Immunology. 112, 2, p. 303-7 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Increased levels of soluble tumour necrosis factor receptor-I (P55) and decreased IgG1 reactivities in HIV-1 patients with cytomegalovirus disease

    Jakobsen, P. H., Dodt, K. K., Meyer, C. N., Katzenstein, T., Gerstoft, Jan & Skinhøj, P., 1998, In: Scandinavian Journal of Immunology. 47, 6, p. 591-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Inflammatory reactions in placental blood of Plasmodium falciparum-infected women and high concentrations of soluble E-selectin and a circulating P. falciparum protein in the cord sera

    Jakobsen, P. H., Rasheed, F. N., Bulmer, J. N., Theisen, Michael, Ridley, R. G. & Greenwood, B. M., 1998, In: Immunology. 93, 2, p. 264-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Limonoids from Khaya senegalensis

    Khalid, S., Friedrichsen, G., Kharazmi, A., Theander, Thor Grundtvig, Olsen, C. & Christensen, Søren Brøgger, 1998, In: Phytochemistry. 49, 6, p. 1769-1772 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Low plasma concentrations of interleukin 10 in severe malarial anaemia compared with cerebral and uncomplicated malaria

    Kurtzhals, Jørgen, Adabayeri, V., Goka, B. Q., Akanmori, B. D., Oliver-Commey, J. O., Nkrumah, F. K., Behr, C. & Hviid, Lars, 1998, In: Lancet. 351, 9118, p. 1768-72 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Modifications of the alpha,beta-double bond in chalcones only marginally affect the antiprotozoal activities

    Nielsen, S. F., Kharazmi, A. & Christensen, Søren Brøgger, 1998, In: Bioorganic & Medicinal Chemistry. 6, 7, p. 937-45 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Neuropsychiatric manifestations after mefloquine therapy for Plasmodium falciparum malaria: comparing a retrospective and a prospective study

    Rønn, A. M., Rønne-Rasmussen, J., Gøtzsche, P. C. & Bygbjerg, Ib Christian, 1998, In: Tropical Medicine & International Health. 3, 2, p. 83-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Polymorphisms in the dihydrofolate reductase (DHFR) and dihydropteroate synthetase (DHPS) genes of Plasmodium falciparum and in vivo resistance to sulphadoxine/pyrimethamine in isolates from Tanzania

    Jelinek, T., Rønn, A. M., Lemnge, M. M., Curtis, J., Mhina, J., Duraisingh, M. T., Bygbjerg, Ib Christian & Warhurst, D. C., 1998, In: Tropical Medicine & International Health. 3, 8, p. 605-9 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Seasonal changes in the Plasmodium falciparum population in individuals and their relationship to clinical malaria: a longitudinal study in a Sudanese village

    Roper, C., Richardson, W., Elhassan, I. M., Giha, H., Hviid, Lars, Satti, G. M., Theander, Thor Grundtvig & Arnot, D. E., 1998, In: Parasitology. 116 ( Pt 6), p. 501-10 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Seasonal variation in agglutination of Plasmodium falciparum-infected erythrocytes.

    Giha, H. A., Theander, Thor Grundtvig, Staalsø, T., Roper, C., Elhassan, I. M., Babiker, H., Satti, G. M., Arnot, D. E. & Hviid, Lars, 1998, In: American Journal of Tropical Medicine and Hygiene. 58, 4, p. 399-405 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The Leishmania promastigote surface antigen-2 (PSA-2) is specifically recognised by Th1 cells in humans with naturally acquired immunity to L. major

    Kemp, M., Handman, E., Kemp, K., Ismail, A., Mustafa, M. D., Kordofani, A. Y., Bendtzen, K., Kharazmi, A. & Theander, Thor Grundtvig, 1998, In: FEMS Immunology and Medical Microbiology. 20, 3, p. 209-18 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The potential antileishmanial activity of some Sudanese medicinal plants

    El Tahir, A., Ibrahim, A. M., Satti, G. M. H., Theander, Thor Grundtvig, Kharazmi, A. & Khalid, S. A., 1998, In: Phytotherapy Research. 12, 8, p. 576-579 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    The role of variant-specific immunity in asymptomatic malaria infections: maintaining a fine balance

    Staalsoe, T. & Hviid, Lars, 1998, In: Trends in Parasitology. 14, 5, p. 177-8 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 1997
  18. Published

    Antibody responses to Rhoptry-Associated Protein-1 (RAP-1) of Plasmodium falciparum parasites in humans from areas of different malaria endemicity

    Jakobsen, P. H., Kurtzhals, Jørgen, Riley, E. M., Hviid, Lars, Theander, Thor Grundtvig, Morris-Jones, S., Jensen, J. B., Bayoumi, R. A., Ridley, R. G. & Greenwood, B. M., 1997, In: Parasite Immunology. 19, 9, p. 387-93 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Antiprotozoal compounds from Asparagus africanus

    Oketch-Rabah, H. A., Dossaji, S. F., Christensen, S. B., Frydenvang, Karla Andrea, Lemmich, E., Cornett, Claus, Olsen, C. E., Chen, M., Kharazmi, A. & Theander, Thor Grundtvig, 1997, In: Journal of Natural Products. 60, 10, p. 1017-22 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Availability and utilization of anti-malarial drugs at community level in Same district north eastern Tanzania

    Alilio, M. S., Kamugisha, M. L., Msuya, F. K., Massaga, J. J., Salum, F. M. & Njunwa, K. J., 1997, In: Malaria and Infectious Diseases in Africa. 6, p. 2

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Decreased plasma levels of factor II + VII + X correlate with increased levels of soluble cytokine receptors in patients with malaria and meningococcal infections

    Bygbjerg, Ib Christian, Hansen, M. B., Rønn, A. M., Bendtzen, K. & Jakobsen, P. H., 1997, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 105, 2, p. 150-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Detection and characterization of Leishmania in tissues of patients with post kala-azar dermal leishmaniasis using a specific monoclonal antibody

    Ismail, A., Kharazmi, A., Permin, H. & Nour-Eldin, Hussam Hassan, 1997, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 91, 3, p. 283-5 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Diagnosis of visceral leishmaniasis by the polymerase chain reaction using blood, bone marrow and lymph node samples from patients from the Sudan

    Andresen, K., Gasim, S., Elhassan, A. M., Khalil, E. A., Barker, D. C., Theander, Thor Grundtvig & Kharazmi, A., 1997, In: Tropical Medicine & International Health. 2, 5, p. 440-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Discovery of oxygenated chalcoes as novel antimalarial agents

    Kharazmi, A., Chen, M., Theander, Thor Grundtvig & Christensen, Søren Brøgger, 1997, In: Annals of Tropical Medicine and Parasitology. 91, p. S91-S95 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Discovery of oxygentade chalcones as novel antimalarial agents

    Kharazmi, A., Chen, M., Theander, Thor Grundtvig & Christensen, Søren Brøgger, 1997, In: Annals of Tropical Medicine and Parasitology. 91, SUPPL. 1, p. S91-S95

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Excretion of ciprofloxacin in sweat and multiresistant Staphylococcus epidermidis

    Høiby, Niels, Jarløv, J. O., Kemp, M., Tvede, M., Bangsborg, Jette Marie, Kjerulf, A., Pers, C. & Hansen, H., 1997, In: Lancet. 349, 9046, p. 167-9 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Ginseng treatment reduces bacterial load and lung pathology in chronic Pseudomonas aeruginosa pneumonia in rats

    Song, Z., Johansen, H. K., Faber, V., Moser, C., Kharazmi, A., Rygaard, J. & Høiby, Niels, 1997, In: Antimicrobial Agents and Chemotherapy. 41, 5, p. 961-4 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    High prevalence of mutations in the dihydrofolate reductase gene of Plasmodium falciparum in isolates from Tanzania without evidence of an association to clinical sulfadoxine/pyrimethamine resistance

    Jelinek, T., Rønn, A. M., Curtis, J., Duraisingh, M. T., Lemnge, M. M., Mhina, J., Bygbjerg, Ib Christian & Warhurst, D. C., 1997, In: Tropical Medicine & International Health. 2, 11, p. 1075-9 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Human T-cell recognition of synthetic peptides representing conserved and variant sequences from the merozoite surface protein 2 of Plasmodium falciparum

    Theander, Thor Grundtvig, Hviid, Lars, Dodoo, D., Afari, E. A., Jensen, J. B. & Rzepczyk, C. M., 1997, In: Immunology Letters. 58, 1, p. 1-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Identification of porcine Pneumocystis carinii as a genetically distinct organism by DNA amplification

    Wakefield, A. E., Keely, S. P., Stringer, J. R., Christensen, C., Ahrens, P., Peters, S. E., Bille-Hansen, V., Henriksen, S. A., Jorsal, S. E. & Settnes, O. P., 1997, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 105, 4, p. 317-21 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Immunity to tetanus and diphtheria in rural Africa

    Kurtzhals, Jørgen, Kjeldsen, K., Hey, A. S., Okong'o-Odera, E. A. & Heron, I., 1997, In: American Journal of Tropical Medicine and Hygiene. 56, 5, p. 576-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Inhibition of LPS and Plasmodium falciparum induced cytokine secretion by pentoxifylline and two analogues

    Jakobsen, P. H., Koch, C. & Bendtzen, K., 1997, In: Scandinavian Journal of Immunology. 45, 5, p. 546-50 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Interferon-¿ production by human T cells and natural killer cells in vitro in response to antigens from the two intracellular pathogens Mycobacterium tuberculosis and Leishmania major

    Kemp, K., Hviid, Lars, Kharazmi, A. & Kemp, M., 1997, In: Scandinavian Journal of Immunology. 46, 5, p. 495-9 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    International aspects of medical research, past, present, and after the year 2000

    Bygbjerg, Ib Christian, 1997, In: Bibliotek for læger. 189, p. 23-36 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Maloprim malaria prophylaxis in children living in a holoendemic village in north-eastern Tanzania

    Lemnge, M. M., Msangeni, H. A., Rønn, A. M., Salum, F. M., Jakobsen, P. H., Mhina, J. I., Akida, J. A. & Bygbjerg, Ib Christian, 1997, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 91, 1, p. 68-73 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Neutrophil chemotactic activity in bronchoalveolar lavage fluid of patients with AIDS-associated Pneumocystis carinii pneumonia

    Benfield, Thomas, Kharazmi, A., Larsen, C. G. & Lundgren, Jens, 1997, In: Scandinavian Journal of Infectious Diseases. 29, 4, p. 367-371 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    New anti-HIV-1, antimalarial, and antifungal compounds from Terminalia bellerica

    Valsaraj, R., Pushpangadan, P., Smitt, U. W., Adsersen, A., Christensen, S. B., Sittie, A., Nyman, U., Nielsen, C. & Olsen, C. E., 1997, In: Journal of Natural Products. 60, 7, p. 739-42 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Rapid reemergence of T cells into peripheral circulation following treatment of severe and uncomplicated Plasmodium falciparum malaria

    Hviid, Lars, Kurtzhals, Jørgen, Goka, B. Q., Oliver-Commey, J. O., Nkrumah, F. K. & Theander, Thor Grundtvig, 1997, In: Infection and Immunity. 65, 10, p. 4090-3 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Regulator and effector functions of T-cell subsets in human Leishmania infections

    Kemp, M., 1997, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 68, p. 1-33 32 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Reversible suppression of bone marrow response to erythropoietin in Plasmodium falciparum malaria

    Kurtzhals, Jørgen, Rodrigues, O., Addae, M., Commey, J. O., Nkrumah, F. K. & Hviid, Lars, 1997, In: British Journal of Haematology. 97, 1, p. 169-74 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Soluble haemoglobin is a marker of recent Plasmodium falciparum infections

    Jakobsen, P. H., Bygbjerg, Ib Christian, Theander, Thor Grundtvig, Hviid, Lars, Fujioka, H., Aikawa, M., Bayoumi, R. A. & Koch, C., 1997, In: Immunology Letters. 59, 1, p. 35-42 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    The novel oxygenated chalcone, 2,4-dimethoxy-4'-butoxychalcone, exhibits potent activity against human malaria parasite Plasmodium falciparum in vitro and rodent parasites Plasmodium berghei and Plasmodium yoelii in vivo

    Chen, M., Christensen, Søren Brøgger, Zhai, L., Rasmussen, M. H., Theander, Thor Grundtvig, Frøkjær, Sven, Steffansen, B., Davidsen, J. & Kharazmi, A., 1997, In: Journal of Infectious Diseases. 176, 5, p. 1327-33 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Two new antiprotozoal 5-methylcoumarins from Vernonia brachycalyx

    Oketch-Rabah, H. A., Lemmich, E., Dossaji, S. F., Theander, Thor Grundtvig, Olsen, C. E., Cornett, Claus, Kharazmi, A. & Christensen, Søren Brøgger, 1997, In: Journal of Natural Products. 60, 5, p. 458-61 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. 1996
  45. Published

    Plasmodium falciparum: characterization of toxin-associated proteins and identification of a hemoglobin containing parasite cytokine stimulator

    Kristensen, G. & Jakobsen, P. H., 1996, In: Experimental Parasitology. 82, 2, p. 147-54 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Antibody reactivities to glutamate-rich peptides of Plasmodium falciparum parasites in humans from areas of different malaria endemicity

    Jakobsen, P. H., Theander, Thor Grundtvig, Hviid, Lars, Morris-Jones, S., Jensen, J. B., Bayoumi, R. A., Greenwood, B. M., Bygbjerg, Ib Christian & Heegaard, P. M., 1996, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 104, 10, p. 734-40 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Bancroftian filariasis: the patterns of filarial-specific immunoglobulin G1 (IgG1), IgG4, and circulating antigens in an endemic community of northeastern Tanzania

    Simonsen, P. E., Lemnge, M. M., Msangeni, H. A., Jakobsen, P. H. & Bygbjerg, Ib Christian, 1996, In: American Journal of Tropical Medicine and Hygiene. 55, 1, p. 69-75 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Detection of very low level Plasmodium falciparum infections using the nested polymerase chain reaction and a reassessment of the epidemiology of unstable malaria in Sudan

    Roper, C., Elhassan, I. M., Hviid, Lars, Giha, H., Richardson, W., Babiker, H., Satti, G. M., Theander, Thor Grundtvig & Arnot, D. E., 1996, In: American Journal of Tropical Medicine and Hygiene. 54, 4, p. 325-31 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Evaluation of the polymerase chain reaction in the diagnosis of cutaneous leishmaniasis due to Leishmania major: a comparison with direct microscopy of smears and sections from lesions

    Andresen, K., Gaafar, A., El-Hassan, A. M., Ismail, A., Dafalla, M., Theander, Thor Grundtvig & Kharazmi, A., 1996, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 90, 2, p. 133-5 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    High level of resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine in children in Tanzania

    Rønn, A. M., Msangeni, H. A., Mhina, J., Wernsdorfer, W. H. & Bygbjerg, Ib Christian, 1996, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 90, 2, p. 179-81 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Immunoglobulin G reactivities to rhoptry-associated protein-1 associated with decreased levels of Plasmodium falciparum parasitemia in Tanzanian children

    Jakobsen, P. H., Lemnge, M. M., Abu-Zeid, Y. A., Msangeni, H. A., Salum, F. M., Mhina, J. I., Akida, J. A., Ruta, A. S., Ronn, A. M., Heegaard, P. M., Ridley, R. G. & Bygbjerg, Ib Christian, 1996, In: American Journal of Tropical Medicine and Hygiene. 55, 6, p. 642-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Immunological properties of meningococcal lipopolysaccharide from serogroups A, B & C

    Jensen, T. J., Kharazmi, A., Shand, G., Nielsen, H. & Tvede, M., 1996, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 104, 1, p. 54-60 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Longitudinal serum HIV RNA quantification: correlation to viral phenotype at seroconversion and clinical outcome

    Katzenstein, T. L., Pedersen, C., Nielsen, C., Lundgren, Jens, Jakobsen, P. H. & Gerstoft, Jan, 1996, In: AIDS. 10, 2, p. 167-73 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review