New anti-HIV-1, antimalarial, and antifungal compounds from Terminalia bellerica

Research output: Contribution to journal › Journal article › Research › peer-review

  • R Valsaraj
  • P Pushpangadan
  • U W Smitt
  • A Adsersen
  • S B Christensen
  • A Sittie
  • U Nyman
  • C Nielsen
  • C E Olsen
A bioactivity-guided fractionation of an extract of Terminalia bellerica fruit rind led to the isolation of two new lignans named termilignan (1) and thannilignan (2), together with 7-hydroxy-3',4'-(methylenedioxy)flavan (3) and anolignan B (4). All four compounds possessed demonstrable anti-HIV-1, antimalarial, and antifungal activity in vitro.
Original languageEnglish
JournalJournal of Natural Products
Volume60
Issue number7
Pages (from-to)739-42
Number of pages3
ISSN0163-3864
DOIs
Publication statusPublished - 1997

Bibliographical note

Keywords: Anti-HIV Agents; Antifungal Agents; Antimalarials; Flavonoids; Lignans; Magnetic Resonance Spectroscopy; Plants, Medicinal

ID: 18055565