Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malaria

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Standard

Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malaria. / Jensen, Anja T R; Zornig, Hanne D; Buhmann, Caecilie; Salanti, Ali; Koram, Kwadwo A; Riley, Eleanor M; Theander, Thor G; Hviid, Lars; Staalsoe, Trine.

In: Infection and Immunity, Vol. 71, No. 7, 2003, p. 4193-6.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Jensen, ATR, Zornig, HD, Buhmann, C, Salanti, A, Koram, KA, Riley, EM, Theander, TG, Hviid, L & Staalsoe, T 2003, 'Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malaria', Infection and Immunity, vol. 71, no. 7, pp. 4193-6. https://doi.org/10.1128/IAI.71.7.4193–4196.2003

APA

Jensen, A. T. R., Zornig, H. D., Buhmann, C., Salanti, A., Koram, K. A., Riley, E. M., Theander, T. G., Hviid, L., & Staalsoe, T. (2003). Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malaria. Infection and Immunity, 71(7), 4193-6. https://doi.org/10.1128/IAI.71.7.4193–4196.2003

Vancouver

Jensen ATR, Zornig HD, Buhmann C, Salanti A, Koram KA, Riley EM et al. Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malaria. Infection and Immunity. 2003;71(7):4193-6. https://doi.org/10.1128/IAI.71.7.4193–4196.2003

Author

Jensen, Anja T R ; Zornig, Hanne D ; Buhmann, Caecilie ; Salanti, Ali ; Koram, Kwadwo A ; Riley, Eleanor M ; Theander, Thor G ; Hviid, Lars ; Staalsoe, Trine. / Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malaria. In: Infection and Immunity. 2003 ; Vol. 71, No. 7. pp. 4193-6.

Bibtex

@article{93ac23a078c711dd81b0000ea68e967b,
title = "Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malaria",
abstract = "Gender-specific and parity-dependent acquired antibody recognition is characteristic of variant surface antigens (VSA) expressed by chondroitin sulfate A (CSA)-adherent Plasmodium falciparum involved in pregnancy-associated malaria (PAM). However, antibody recognition of recombinant products of a specific VSA gene (2O2var1) implicated in PAM and transcribed by a CSA-adhering parasite line did not have these characteristics. Furthermore, we could not demonstrate preferential transcription of 2O2var1 in the CSA-adhering line versus the unselected, parental isolate. Our data call for circumspection regarding the molecular identity of the parasite ligand mediating adhesion to CSA in PAM.",
author = "Jensen, {Anja T R} and Zornig, {Hanne D} and Caecilie Buhmann and Ali Salanti and Koram, {Kwadwo A} and Riley, {Eleanor M} and Theander, {Thor G} and Lars Hviid and Trine Staalsoe",
note = "Keywords: Animals; Antibodies, Protozoan; Chondroitin Sulfates; Female; Humans; Immunoglobulin G; Malaria, Falciparum; Male; Parity; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic; Protozoan Proteins; Sex Factors",
year = "2003",
doi = "10.1128/IAI.71.7.4193–4196.2003",
language = "English",
volume = "71",
pages = "4193--6",
journal = "Infection and Immunity",
issn = "0019-9567",
publisher = "American Society for Microbiology",
number = "7",

}

RIS

TY - JOUR

T1 - Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malaria

AU - Jensen, Anja T R

AU - Zornig, Hanne D

AU - Buhmann, Caecilie

AU - Salanti, Ali

AU - Koram, Kwadwo A

AU - Riley, Eleanor M

AU - Theander, Thor G

AU - Hviid, Lars

AU - Staalsoe, Trine

N1 - Keywords: Animals; Antibodies, Protozoan; Chondroitin Sulfates; Female; Humans; Immunoglobulin G; Malaria, Falciparum; Male; Parity; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic; Protozoan Proteins; Sex Factors

PY - 2003

Y1 - 2003

N2 - Gender-specific and parity-dependent acquired antibody recognition is characteristic of variant surface antigens (VSA) expressed by chondroitin sulfate A (CSA)-adherent Plasmodium falciparum involved in pregnancy-associated malaria (PAM). However, antibody recognition of recombinant products of a specific VSA gene (2O2var1) implicated in PAM and transcribed by a CSA-adhering parasite line did not have these characteristics. Furthermore, we could not demonstrate preferential transcription of 2O2var1 in the CSA-adhering line versus the unselected, parental isolate. Our data call for circumspection regarding the molecular identity of the parasite ligand mediating adhesion to CSA in PAM.

AB - Gender-specific and parity-dependent acquired antibody recognition is characteristic of variant surface antigens (VSA) expressed by chondroitin sulfate A (CSA)-adherent Plasmodium falciparum involved in pregnancy-associated malaria (PAM). However, antibody recognition of recombinant products of a specific VSA gene (2O2var1) implicated in PAM and transcribed by a CSA-adhering parasite line did not have these characteristics. Furthermore, we could not demonstrate preferential transcription of 2O2var1 in the CSA-adhering line versus the unselected, parental isolate. Our data call for circumspection regarding the molecular identity of the parasite ligand mediating adhesion to CSA in PAM.

U2 - 10.1128/IAI.71.7.4193–4196.2003

DO - 10.1128/IAI.71.7.4193–4196.2003

M3 - Journal article

C2 - 12819117

VL - 71

SP - 4193

EP - 4196

JO - Infection and Immunity

JF - Infection and Immunity

SN - 0019-9567

IS - 7

ER -

ID: 5831862