Anja Ramstedt Jensen
Professor
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3D blood-brain barrier-organoids as a model for Lyme neuroborreliosis highlighting genospecies dependent organotropism
Adams, Yvonne, Clausen, Anne Skovsbo, Jensen, Peter Østrup, Lager, M., Wilhelmsson, P., Henningson, A. J., Lindgren, P. E., Faurholt-Jepsen, D., Mens, H., Kraiczy, P., Kragh, K. N., Bjarnsholt, Thomas, Kjær, Andreas, Lebech, Anne-Mette & Jensen, Anja Ramstedt, 2023, In: iScience. 26, 1, 105838.Research output: Contribution to journal › Journal article › Research › peer-review
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3D organoid assay of the impact of infected erythrocyte adhesion on the blood-brain barrier
Adams, Yvonne & Jensen, Anja Ramstedt, 2022, Malaria Immunology: Targeting the Surface of Infected Erythrocytes. Humana Press, Vol. 2470. p. 587-599 13 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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3D7-derived Plasmodium falciparum erythrocyte membrane protein 1 is a frequent target of naturally acquired antibodies recognizing protein domains in a particular pattern independent of malaria transmission intensity
Joergensen, L., Vestergaard, L. S., Turner, Louise, Magistrado, P., Lusingu, J. P., Lemnge, M., Theander, Thor Grundtvig & Jensen, Anja Ramstedt, 2007, In: Journal of Immunology. 178, 1, p. 428-35 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Baculovirus-expressed constructs induce immunoglobulin G that recognizes VAR2CSA on Plasmodium falciparum-infected erythrocytes
Barfod, Lea Klingenberg, Nielsen, Morten Agertoug, Turner, Louise, Dahlbäck, M., Jensen, Anja Ramstedt, Hviid, Lars, Theander, Thor Grundtvig & Salanti, Ali, 2006, In: Infection and Immunity. 74, 7, p. 4357-60 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro selection of Plasmodium falciparum 3D7 for expression of variant surface antigens associated with severe malaria in African children
Staalsoe, T., Nielsen, Morten Agertoug, Vestergaard, L. S., Jensen, Anja Ramstedt, Theander, Thor Grundtvig & Hviid, Lars, 2003, In: Parasite Immunology. 25, 8-9, p. 421-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes
Jensen, Anja Ramstedt, Magistrado, P., Sharp, S., Joergensen, L., Lavstsen, Thomas, Chiucchiuini, A., Salanti, Ali, Vestergaard, L. S., Lusingu, J. P., Hermsen, R., Sauerwein, R., Christensen, J., Nielsen, Morten Agertoug, Hviid, Lars, Sutherland, C., Staalsoe, T. & Theander, Thor Grundtvig, 2004, In: Journal of Experimental Medicine. 199, 9, p. 1179-90 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum erythrocyte membrane protein 1 variants induce cell swelling and disrupt the blood-brain barrier in cerebral malaria
Adams, Yvonne, Olsen, Rebecca Wendelboe, Bengtsson, A., Dalgaard, Nanna, Zdioruk, M., Satpathi, S., Behera, P. K., Sahu, P. K., Lawler, S. E., Qvortrup, Klaus, Wassmer, S. C. & Jensen, Anja Ramstedt, 2021, In: The Journal of Experimental Medicine. 218, 3, 16 p., e20201266.Research output: Contribution to journal › Journal article › Research › peer-review
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A Novel Domain Cassette Identifies Plasmodium falciparum PfEMP1 Proteins Binding ICAM-1 and Is a Target of Cross-Reactive, Adhesion-Inhibitory Antibodies
Bengtsson, A., Joergensen, L., Rask, T. S., Olsen, R. W., Andersen, M. A., Turner, Louise, Theander, Thor Grundtvig, Hviid, Lars, Higgins, M. K., Craig, A., Brown, A. & Jensen, Anja Ramstedt, 2013, In: Journal of Immunology. 190, 1, p. 240-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A method for visualizing surface-exposed and internal PfEMP1 adhesion antigens in Plasmodium falciparum infected erythrocytes
Bengtsson, D., Sowa, K. M., Salanti, Ali, Jensen, Anja Ramstedt, Joergensen, L., Turner, Louise, Theander, Thor Grundtvig & Arnot, D. E., 2008, In: Malaria Journal. 7, p. 101Research output: Contribution to journal › Journal article › Research › peer-review
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A semi-automated multiplex high-throughput assay for measuring IgG antibodies against Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) domains in small volumes of plasma
Cham, G. K. K., Kurtis, J., Lusingu, J., Theander, Thor Grundtvig, Jensen, Anja Ramstedt & Turner, Louise, 2008, In: Malaria Journal. 7, p. 108Research output: Contribution to journal › Journal article › Research › peer-review
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A specific PfEMP1 is expressed in P. falciparum sporozoites and plays a role in hepatocyte infection
Zanghì, G., Vembar, S. S., Baumgarten, S., Ding, S., Guizetti, J., Bryant, J. M., Mattei, D., Jensen, A. T. R., Rénia, L., Goh, Y. S., Sauerwein, R., Hermsen, C. C., Franetich, J-F., Bordessoulles, M., Silvie, O., Soulard, V., Scatton, O., Chen, P., Mecheri, S., Mazier, D. & 1 others, , 2018, In: Cell Reports. 22, 11, p. 2951-2963 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A sub-family of common and highly conserved Plasmodium falciparum var genes
Salanti, Ali, Jensen, Anja Ramstedt, Zornig, H. D., Staalsoe, T., Joergensen, L., Nielsen, Morten Agertoug, Khattab, A., Arnot, D. E., Klinkert, M. Q., Hviid, Lars & Theander, Thor Grundtvig, 2002, In: Molecular and Biochemical Parasitology. 122, 1, p. 111-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A vaccine targeted specifically to prevent cerebral malaria - is there hope?
Hviid, Lars, Lavstsen, Thomas & Jensen, Anja Ramstedt, Jul 2018, In: Expert Review of Vaccines. 17, 7, p. 565-567 3 p.Research output: Contribution to journal › Letter › Research › peer-review
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Acquisition of IgG to ICAM-1-Binding DBLβ Domains in the Plasmodium falciparum erythrocyte membrane protein 1 antigen family varies between Groups A, B, and C
Olsen, Rebecca Wendelboe, Ecklu-Mensah, G., Bengtsson, A., Ofori, M. F., Kusi, K. A., Koram, K. A., Hviid, Lars, Adams, Yvonne & Jensen, Anja Ramstedt, 2019, In: Infection and Immunity. 87, 10, e00224-19.Research output: Contribution to journal › Journal article › Research › peer-review
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Activated integrins identify functional antigen-specific CD8 T cells within minutes after antigen stimulation
Dimitrov, S., Gouttefangeas, C., Besedovsky, L., Jensen, Anja Ramstedt, Chandran, P. A., Rusch, E., Businger, R., Schindler, M., Lange, T., Born, J. & Rammensee, H., 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 24, p. E5536-E5545Research output: Contribution to journal › Journal article › Research › peer-review
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Affinity purification of PfEMP1-specific antibodies from human blood
Olsen, Rebecca Wendelboe, Suurbaar, Jennifer & Jensen, Anja Ramstedt, 2022, Malaria Immunology: Targeting the Surface of Infected Erythrocytes. Humana Press, Vol. 2470. p. 369-379 11 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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An analysis of the binding characteristics of a panel of recently selected ICAM-1 binding Plasmodium falciparum patient isolates
Madkhali, A. M., Alkurbi, M. O., Szestak, T., Bengtsson, A., Patil, P. R., Wu, Y., Alharthi, S., Jensen, Anja Ramstedt, Pleass, R. & Craig, A. G., 2014, In: PLOS ONE. 9, 10, 8 p., e111518.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of Single-cell Gene Transcription by RNA Fluorescent In Situ Hybridization (FISH)
Ronander, E., Bengtsson, D. C., Joergensen, L., Jensen, Anja Ramstedt & Arnot, D. E., 2012, In: Journal of Visualized Experiments. 68Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of antibody inhibition of PfEMP1 binding by competition ELISA
Olsen, Rebecca Wendelboe, Suurbaar, Jennifer & Jensen, Anja Ramstedt, 2022, Malaria Immunology: Targeting the Surface of Infected Erythrocytes. Humana Press, Vol. 2470. p. 485-491 7 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Antigenic variation and the genetics and epigenetics of the PfEMP1 erythrocyte surface antigens in Plasmodium falciparum malaria
Arnot, D. E. & Jensen, Anja Ramstedt, 2011, In: Advances in Applied Microbiology. 74, p. 77-96 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Blood outgrowth endothelial cells (BOECs) as a novel tool for studying adhesion of Plasmodium falciparum-infected erythrocytes
Ecklu-Mensah, G., Olsen, Rebecca Wendelboe, Bengtsson, A., Ofori, M. F., Hviid, Lars, Jensen, Anja Ramstedt & Adams, Yvonne, 2018, In: PLoS ONE. 13, 10, 12 p., e0204177.Research output: Contribution to journal › Journal article › Research › peer-review
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Breadth of antibodies to Plasmodium falciparum variant surface antigens is associated with immunity in a controlled human malaria infection study
CHMI-SIKA Study Team, C. S. T., 2022, In: Frontiers in Immunology. 13, 10 p., 894770.Research output: Contribution to journal › Journal article › Research › peer-review
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CD36 selection of 3D7 Plasmodium falciparum associated with severe childhood malaria results in reduced VAR4 expression
Magistrado, P., Staalsoe, T., Theander, Thor Grundtvig, Hviid, Lars & Jensen, Anja Ramstedt, 2008, In: Malaria Journal. 7, 1, p. 204Research output: Contribution to journal › Journal article › Research › peer-review
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Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1-based vaccines to prevent it
Jensen, Anja Ramstedt, Adams, Yvonne & Hviid, Lars, 2020, In: Immunological Reviews. 293, 1, p. 230-252Research output: Contribution to journal › Review › Research › peer-review
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Cerebral malaria - modelling interactions at the blood-brain barrier in vitro
Adams, Yvonne & Jensen, Anja Ramstedt, 2022, In: Disease models & mechanisms. 15, 7, dmm049410.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterizing the impact of sustained sulfadoxine/pyrimethamine use upon the Plasmodium falciparum population in Malawi
Ravenhall, M., Benavente, E. D., Mipando, M., Jensen, Anja Ramstedt, Sutherland, C. J., Roper, C., Sepúlveda, N., Kwiatkowski, D. P., Montgomery, J., Phiri, K. S., Terlouw, A., Craig, A., Campino, S., Ocholla, H. & Clark, T. G., 29 Nov 2016, In: Malaria Journal. 15, 11 p., 575.Research output: Contribution to journal › Journal article › Research › peer-review
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Chip-based assay of adhesion of Plasmodium falciparum-infected erythrocytes to cells under flow
Adams, Yvonne & Jensen, Anja Ramstedt, 2022, Malaria Immunology: Targeting the Surface of Infected Erythrocytes. Jensen, A. T. R. & Hviid, L. (eds.). Humana Press, p. 545-556 12 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Cloning, expression and antigenicity of the L. donovani reductase
Jensen, Anja Ramstedt, Kemp, K., Theander, Thor Grundtvig & Handman, E., 2001, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 109, 6, p. 461-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Compounds useful in the diagnosis and treatment of pregnancy-associated malaria
Theander, Thor Grundtvig, Salanti, Ali, Hviid, Lars, Staalsø, Trine, Jensen, Anja Ramstedt, Lavstsen, Thomas & Dahlbäck, M., 2004, Patent No. WO2004067559 A1, Priority date 27 Jan 2003, Priority No. WO2004067559 A1Research output: Patent
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Differential expression of var gene groups is associated with morbidity caused by Plasmodium falciparum infection in Tanzanian children
Rottmann, M., Lavstsen, Thomas, Mugasa, J. P., Kaestli, M., Jensen, Anja Ramstedt, Müller, D., Theander, Thor Grundtvig & Beck, H., 2006, In: Infection and Immunity. 74, 7, p. 3904-11 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evidence for the involvement of VAR2CSA in pregnancy-associated malaria
Salanti, Ali, Dahlbäck, M., Turner, Louise, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Magistrado, P., Jensen, Anja Ramstedt, Lavstsen, Thomas, Ofori, M. F., Marsh, K., Hviid, Lars & Theander, Thor Grundtvig, 2004, In: Journal of Experimental Medicine. 200, 9, p. 1197-203 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria
Zhang, Q., Siegel, T. N., Martins, R. M., Wang, F., Cao, J., Gao, Q., Cheng, X., Jiang, L., Hon, C., Scheidig-Benatar, C., Sakamoto, H., Turner, Louise, Jensen, Anja Ramstedt, Claes, A., Guizetti, J., Malmquist, N. A. & Scherf, A., 2014, In: Nature. 531, p. 431-435Research output: Contribution to journal › Journal article › Research › peer-review
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Expression of Plasmodium falciparum erythrocyte membrane protein 1 in experimentally infected humans
Lavstsen, Thomas, Magistrado, P., Hermsen, C. C., Salanti, Ali, Jensen, Anja Ramstedt, Sauerwein, R., Hviid, Lars, Theander, Thor Grundtvig & Staalsoe, T., 2005, In: Malaria Journal. 4, 1, p. 21Research output: Contribution to journal › Journal article › Research › peer-review
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Gαs-coupled receptor signaling and sleep regulate integrin activation of human antigen-specific T cells
Dimitrov, S., Lange, T., Gouttefangeas, C., Jensen, Anja Ramstedt, Szczepanski, M., Lehnnolz, J., Soekadar, S., Rammensee, H., Born, J. & Besedovsky, L., 2019, In: The Journal of Experimental Medicine. 216, 3, p. 517-526 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian children
Cham, G. K. K., Turner, Louise, Kurtis, J. D., Mutabingwa, T., Fried, M., Jensen, Anja Ramstedt, Lavstsen, Thomas, Hviid, Lars, Duffy, P. E. & Theander, Thor Grundtvig, 2010, In: Infection and Immunity. 78, 11, p. 4653-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Humoral and cellular immune responses to glucose regulated protein 78 - a novel Leishmania donovani antigen
Jensen, Anja Ramstedt, Ismail, A., Gaafar, A., El Hassan, A. M. & Theander, Thor Grundtvig, 2002, In: Tropical Medicine & International Health. 7, 5, p. 471-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Humoral and cellular immune responses to synthetic peptides of the Leishmania donovani kinetoplastid membrane protein-11
Jensen, Anja Ramstedt, Gasim, S., Ismail, A., Gaafar, A., Kurtzhals, Jørgen, Kemp, M., El Hassan, A. M., Kharazmi, A. & Theander, Thor Grundtvig, 1998, In: Scandinavian Journal of Immunology. 48, 1, p. 103-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ICAM-1-binding Plasmodium falciparum erythrocyte membrane protein 1 variants elicits opsonic-phagocytosis IgG responses in Beninese children
Suurbaar, Jennifer, Moussiliou, A., Tahar, R., Olsen, Rebecca Wendelboe, Adams, Yvonne, Dalgaard, Nanna, Baafour, E. K., Adukpo, S., Hviid, Lars, Kusi, K. A., Alao, J., Ofori, M. F., Ndam, N. T. & Jensen, Anja Ramstedt, 2022, In: Scientific Reports. 12, 12994.Research output: Contribution to journal › Journal article › Research › peer-review
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IRDye800CW labeled uPAR-targeting peptide for fluorescence-guided glioblastoma surgery: Preclinical studies in orthotopic xenografts
Kurbegovic, Sorel, Stræde, Karina, Sørensen, K. K., Leth, Julie Maja, Willemoe, G. L., Christensen, Anders, Adams, Yvonne, Jensen, Anja Ramstedt, von Buchwald, Christian, Skjøth-rasmussen, J., Ploug, Michael, Jensen, Knud Jørgen & Kjær, Andreas, 2021, In: Theranostics. 11, 15, p. 7159-7174 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Immunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malaria
Magistrado, P. A., Lusingu, J., Vestergaard, L. S., Lemnge, M., Lavstsen, Thomas, Turner, Louise, Hviid, Lars, Jensen, Anja Ramstedt & Theander, Thor Grundtvig, 2007, In: Infection and Immunity. 75, 5, p. 2415-20 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Insect cells are superior to Escherichia coli in producing malaria proteins inducing IgG targeting PfEMP1 on infected erythrocytes
Victor, M. E., Bengtsson, A., Andersen, G., Bengtsson, D., Lusingu, J. P., Vestergaard, L. S., Arnot, D. E., Theander, Thor Grundtvig, Joergensen, L. & Jensen, Anja Ramstedt, 2010, In: Malaria Journal. 9, p. 325Research output: Contribution to journal › Journal article › Research › peer-review
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Integrin activation enables sensitive detection of functional CD4+ and CD8+ T cells: Application to characterize SARS-CoV-2 immunity
Schöllhorn, A., Schuhmacher, J., Besedovsky, L., Fendel, R., Jensen, Anja Ramstedt, Stevanović, S., Lange, T., Rammensee, H., Born, J., Gouttefangeas, C. & Dimitrov, S., 2021, In: Frontiers in Immunology. 12, 626308.Research output: Contribution to journal › Journal article › Research › peer-review
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Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malaria
Jensen, Anja Ramstedt, Zornig, H. D., Buhmann, Cæcilie Christine Böck, Salanti, Ali, Koram, K. A., Riley, E. M., Theander, Thor Grundtvig, Hviid, Lars & Staalsoe, T., 2003, In: Infection and Immunity. 71, 7, p. 4193-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Levels of plasma immunoglobulin G with specificity against the cysteine-rich interdomain regions of a semiconserved Plasmodium falciparum erythrocyte membrane protein 1, VAR4, predict protection against malarial anemia and febrile episodes
Lusingu, J. P. A., Jensen, Anja Ramstedt, Vestergaard, L. S., Minja, D. T., Dalgaard, M. B., Gesase, S., Mmbando, B. P., Kitua, A. Y., Lemnge, M. M., Cavanagh, D., Hviid, Lars & Theander, Thor Grundtvig, 2006, In: Infection and Immunity. 74, 5, p. 2867-75 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Limited cross-reactivity among domains of the Plasmodium falciparum clone 3D7 erythrocyte membrane protein 1 family
Joergensen, L., Turner, Louise, Magistrado, P., Dahlbäck, M. A., Vestergaard, L. S., Lusingu, J. P., Lemnge, M., Salanti, Ali, Theander, Thor Grundtvig & Jensen, Anja Ramstedt, 2006, In: Infection and Immunity. 74, 12, p. 6778-84 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Malaria immunology: Targeting the surface of infected erythrocytes
Jensen, Anja Ramstedt (ed.) & Hviid, Lars (ed.), 2022, Humana Press. 796 p. (Methods in Molecular Biology, Vol. 2470).Research output: Book/Report › Book › Research › peer-review
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Mapping the binding site of a cross-reactive Plasmodium falciparum PfEMP1 monoclonal antibody inhibitory of ICAM-1 binding
Lennartz, F., Bengtsson, A., Olsen, Rebecca Wendelboe, Joergensen, L., Brown, A., Remy, L., Man, P., Forest, E., Barfod, Lea Klingenberg, Adams, Yvonne, Higgins, M. K. & Jensen, Anja Ramstedt, 2015, In: Journal of immunology (Baltimore, Md. : 1950). 195, 7, p. 3273-83 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular and immunological characterisation of the glucose regulated protein 78 of Leishmania donovani
Jensen, Anja Ramstedt, Curtis, J., Montgomery, J., Handman, E. & Theander, Thor Grundtvig, 2001, In: BBA General Subjects. 1549, 1, p. 73-87 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular characterization of a Leishmania donovani cDNA clone with similarity to human 20S proteasome a-type subunit
Christensen, C. B., Jørgensen, L., Jensen, Anja Ramstedt, Gasim, S., Chen, M., Kharazmi, A., Theander, Thor Grundtvig & Andresen, K., 2000, In: BBA General Subjects. 1500, 1, p. 77-87 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural and vaccine-induced acquisition of cross-reactive IgG inhibiting ICAM-1-specific binding of a Plasmodium falciparum PfEMP1 subtype associated specifically with cerebral malaria
Olsen, Rebecca Wendelboe, Ecklu-Mensah, G., Bengtsson, A., Ofori, M. F., Lusingu, J. P. A., Castberg, F. C., Hviid, Lars, Adams, Yvonne & Jensen, Anja Ramstedt, 2018, In: Infection and Immunity. 86, 4, 17 p., e00622-17.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11501
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Structure-guided identification of a family of dual receptor-binding PfEMP1 that is associated with cerebral malaria
Research output: Contribution to journal › Journal article › Research › peer-review
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180
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IRDye800CW labeled uPAR-targeting peptide for fluorescence-guided glioblastoma surgery: Preclinical studies in orthotopic xenografts
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
177
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Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1-based vaccines to prevent it
Research output: Contribution to journal › Review › Research › peer-review
Published