Selection of antimalarial drug resistance after intermittent preventive treatment of infants and children (IPTi/c) in Senegal

Research output: Contribution to journal › Journal article › Research › peer-review

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Selection of antimalarial drug resistance after intermittent preventive treatment of infants and children (IPTi/c) in Senegal. / Ndiaye, Magatte; Tine, Roger; Faye, Babacar; Ndiaye, Jean L; Diouf, Ibrahima; Lo, Aminata C; Sylla, Khadime; Dieng, Yemou; Hallett, Rachel; Alifrangis, Michael; Gaye, Oumar.

In: Comptes Rendus Biologies, Vol. 336, No. 5-6, 2013, p. 295-300.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Ndiaye, M, Tine, R, Faye, B, Ndiaye, JL, Diouf, I, Lo, AC, Sylla, K, Dieng, Y, Hallett, R, Alifrangis, M & Gaye, O 2013, 'Selection of antimalarial drug resistance after intermittent preventive treatment of infants and children (IPTi/c) in Senegal', Comptes Rendus Biologies, vol. 336, no. 5-6, pp. 295-300. https://doi.org/10.1016/j.crvi.2013.04.016

APA

Ndiaye, M., Tine, R., Faye, B., Ndiaye, J. L., Diouf, I., Lo, A. C., Sylla, K., Dieng, Y., Hallett, R., Alifrangis, M., & Gaye, O. (2013). Selection of antimalarial drug resistance after intermittent preventive treatment of infants and children (IPTi/c) in Senegal. Comptes Rendus Biologies, 336(5-6), 295-300. https://doi.org/10.1016/j.crvi.2013.04.016

Vancouver

Ndiaye M, Tine R, Faye B, Ndiaye JL, Diouf I, Lo AC et al. Selection of antimalarial drug resistance after intermittent preventive treatment of infants and children (IPTi/c) in Senegal. Comptes Rendus Biologies. 2013;336(5-6):295-300. https://doi.org/10.1016/j.crvi.2013.04.016

Author

Ndiaye, Magatte ; Tine, Roger ; Faye, Babacar ; Ndiaye, Jean L ; Diouf, Ibrahima ; Lo, Aminata C ; Sylla, Khadime ; Dieng, Yemou ; Hallett, Rachel ; Alifrangis, Michael ; Gaye, Oumar. / Selection of antimalarial drug resistance after intermittent preventive treatment of infants and children (IPTi/c) in Senegal. In: Comptes Rendus Biologies. 2013 ; Vol. 336, No. 5-6. pp. 295-300.

Bibtex

@article{f3da9478e2274af0ae9e7d30d66f6fc7,
title = "Selection of antimalarial drug resistance after intermittent preventive treatment of infants and children (IPTi/c) in Senegal",
abstract = "Senegal has since 2003 used sulphadoxine-pyrimethamine (SP) for Intermittent Preventive Treatment (IPT) of malaria in risk groups. However, the large-scale IPT strategy may result in increasing drug resistance. Our study investigated the possible impact of SP-IPT given to infants and children on the prevalence of SP-resistant haplotypes in the Plasmodium falciparum genes Pfdhfr and Pfdhps, comparing sites with and without IPTi/c. P. falciparum positives samples (n=352) were collected from children under 5years of age during two cross-sectional surveys in 2010 and 2011 in three health districts (two on IPTi/c and one without IPTi/c intervention) located in the southern part of Senegal. The prevalence of SP-resistance-related haplotypes in Pfdhfr and Pfdhps was determined by nested PCR followed by sequence-specific oligonucleotide probe (SSOP)-ELISA. The prevalence of the Pfdhfr double mutant haplotypes (CNRN and CICN) was stable between years at",
author = "Magatte Ndiaye and Roger Tine and Babacar Faye and Ndiaye, {Jean L} and Ibrahima Diouf and Lo, {Aminata C} and Khadime Sylla and Yemou Dieng and Rachel Hallett and Michael Alifrangis and Oumar Gaye",
note = "Copyright {\textcopyright} 2013 Acad{\'e}mie des sciences. Published by Elsevier SAS. All rights reserved.",
year = "2013",
doi = "10.1016/j.crvi.2013.04.016",
language = "English",
volume = "336",
pages = "295--300",
journal = "Comptes Rendus - Academie des Sciences, Serie III: Sciences de la Vie",
issn = "0764-4469",
publisher = "Elsevier",
number = "5-6",

}

RIS

TY - JOUR

T1 - Selection of antimalarial drug resistance after intermittent preventive treatment of infants and children (IPTi/c) in Senegal

AU - Ndiaye, Magatte

AU - Tine, Roger

AU - Faye, Babacar

AU - Ndiaye, Jean L

AU - Diouf, Ibrahima

AU - Lo, Aminata C

AU - Sylla, Khadime

AU - Dieng, Yemou

AU - Hallett, Rachel

AU - Alifrangis, Michael

AU - Gaye, Oumar

N1 - Copyright © 2013 Académie des sciences. Published by Elsevier SAS. All rights reserved.

PY - 2013

Y1 - 2013

N2 - Senegal has since 2003 used sulphadoxine-pyrimethamine (SP) for Intermittent Preventive Treatment (IPT) of malaria in risk groups. However, the large-scale IPT strategy may result in increasing drug resistance. Our study investigated the possible impact of SP-IPT given to infants and children on the prevalence of SP-resistant haplotypes in the Plasmodium falciparum genes Pfdhfr and Pfdhps, comparing sites with and without IPTi/c. P. falciparum positives samples (n=352) were collected from children under 5years of age during two cross-sectional surveys in 2010 and 2011 in three health districts (two on IPTi/c and one without IPTi/c intervention) located in the southern part of Senegal. The prevalence of SP-resistance-related haplotypes in Pfdhfr and Pfdhps was determined by nested PCR followed by sequence-specific oligonucleotide probe (SSOP)-ELISA. The prevalence of the Pfdhfr double mutant haplotypes (CNRN and CICN) was stable between years at

AB - Senegal has since 2003 used sulphadoxine-pyrimethamine (SP) for Intermittent Preventive Treatment (IPT) of malaria in risk groups. However, the large-scale IPT strategy may result in increasing drug resistance. Our study investigated the possible impact of SP-IPT given to infants and children on the prevalence of SP-resistant haplotypes in the Plasmodium falciparum genes Pfdhfr and Pfdhps, comparing sites with and without IPTi/c. P. falciparum positives samples (n=352) were collected from children under 5years of age during two cross-sectional surveys in 2010 and 2011 in three health districts (two on IPTi/c and one without IPTi/c intervention) located in the southern part of Senegal. The prevalence of SP-resistance-related haplotypes in Pfdhfr and Pfdhps was determined by nested PCR followed by sequence-specific oligonucleotide probe (SSOP)-ELISA. The prevalence of the Pfdhfr double mutant haplotypes (CNRN and CICN) was stable between years at

U2 - 10.1016/j.crvi.2013.04.016

DO - 10.1016/j.crvi.2013.04.016

M3 - Journal article

C2 - 23916206

VL - 336

SP - 295

EP - 300

JO - Comptes Rendus - Academie des Sciences, Serie III: Sciences de la Vie

JF - Comptes Rendus - Academie des Sciences, Serie III: Sciences de la Vie

SN - 0764-4469

IS - 5-6

ER -

ID: 48881262