mSphere of Influence: Structural insights into the molecular mechanism underlying placental malaria

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mSphere of Influence : Structural insights into the molecular mechanism underlying placental malaria. / Quintana, Maria Del Pilar.

In: mSphere, Vol. 6, No. 3, e00391-21 , 2021.

Research output: Contribution to journal › Comment/debate › Research › peer-review

Harvard

Quintana, MDP 2021, 'mSphere of Influence: Structural insights into the molecular mechanism underlying placental malaria', mSphere, vol. 6, no. 3, e00391-21 . https://doi.org/10.1128/mSphere.00391-21

APA

Quintana, M. D. P. (2021). mSphere of Influence: Structural insights into the molecular mechanism underlying placental malaria. mSphere, 6(3), [e00391-21 ]. https://doi.org/10.1128/mSphere.00391-21

Vancouver

Quintana MDP. mSphere of Influence: Structural insights into the molecular mechanism underlying placental malaria. mSphere. 2021;6(3). e00391-21 . https://doi.org/10.1128/mSphere.00391-21

Author

Quintana, Maria Del Pilar. / mSphere of Influence : Structural insights into the molecular mechanism underlying placental malaria. In: mSphere. 2021 ; Vol. 6, No. 3.

Bibtex

@article{c7febf6bebc24042bfcef96ebb3be075,
title = "mSphere of Influence: Structural insights into the molecular mechanism underlying placental malaria",
abstract = "Maria del Pilar Quintana works on immunology and pathogenesis of severe malaria. In this mSphere of Influence article, she reflects on how the papers {"}Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA{"} (R. Ma, T. Lian, R. Huang, J. P. Renn, J. D. Petersen, J. Zimmerberg, P. E. Duffy, N. H. Tolia, Nat Microbiol 6:380-391, 2021, https://doi.org/10.1038/s41564-020-00858-9) and {"}Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding{"} (K. Wang, R. Dagil, T. Lavsten, S. K. Misra, C. B. Spliid, Y. Wang, T. Gustavsson, D. R. Sandoval, E. E. Vidal-Calvo, S. Choudary, M. O. Agerback, K. Lindorff-Larsen, M. A. Nielsen, T. G. Theander, J. S. Sharp, T. M. Clausen, P. Gourdon, A. Salanti, A. Salanti, Nat Commun 12:2956, 2021, https://doi.org/10.1038/s41467-021-23254-1) shed light on the precise structural details behind Plasmodium falciparum VAR2CSA binding to chondroitin sulfate A (CSA) in the placenta and how these novel insights have changed the way she will approach her work toward the discovery of new broadly cross-reactive/inhibitory antibodies targeting VAR2CSA.",
author = "Quintana, {Maria Del Pilar}",
year = "2021",
doi = "10.1128/mSphere.00391-21",
language = "English",
volume = "6",
journal = "mSphere",
issn = "2379-5042",
publisher = "American Society for Microbiology",
number = "3",

}

RIS

TY - JOUR

T1 - mSphere of Influence

T2 - Structural insights into the molecular mechanism underlying placental malaria

AU - Quintana, Maria Del Pilar

PY - 2021

Y1 - 2021

N2 - Maria del Pilar Quintana works on immunology and pathogenesis of severe malaria. In this mSphere of Influence article, she reflects on how the papers "Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA" (R. Ma, T. Lian, R. Huang, J. P. Renn, J. D. Petersen, J. Zimmerberg, P. E. Duffy, N. H. Tolia, Nat Microbiol 6:380-391, 2021, https://doi.org/10.1038/s41564-020-00858-9) and "Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding" (K. Wang, R. Dagil, T. Lavsten, S. K. Misra, C. B. Spliid, Y. Wang, T. Gustavsson, D. R. Sandoval, E. E. Vidal-Calvo, S. Choudary, M. O. Agerback, K. Lindorff-Larsen, M. A. Nielsen, T. G. Theander, J. S. Sharp, T. M. Clausen, P. Gourdon, A. Salanti, A. Salanti, Nat Commun 12:2956, 2021, https://doi.org/10.1038/s41467-021-23254-1) shed light on the precise structural details behind Plasmodium falciparum VAR2CSA binding to chondroitin sulfate A (CSA) in the placenta and how these novel insights have changed the way she will approach her work toward the discovery of new broadly cross-reactive/inhibitory antibodies targeting VAR2CSA.

AB - Maria del Pilar Quintana works on immunology and pathogenesis of severe malaria. In this mSphere of Influence article, she reflects on how the papers "Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA" (R. Ma, T. Lian, R. Huang, J. P. Renn, J. D. Petersen, J. Zimmerberg, P. E. Duffy, N. H. Tolia, Nat Microbiol 6:380-391, 2021, https://doi.org/10.1038/s41564-020-00858-9) and "Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding" (K. Wang, R. Dagil, T. Lavsten, S. K. Misra, C. B. Spliid, Y. Wang, T. Gustavsson, D. R. Sandoval, E. E. Vidal-Calvo, S. Choudary, M. O. Agerback, K. Lindorff-Larsen, M. A. Nielsen, T. G. Theander, J. S. Sharp, T. M. Clausen, P. Gourdon, A. Salanti, A. Salanti, Nat Commun 12:2956, 2021, https://doi.org/10.1038/s41467-021-23254-1) shed light on the precise structural details behind Plasmodium falciparum VAR2CSA binding to chondroitin sulfate A (CSA) in the placenta and how these novel insights have changed the way she will approach her work toward the discovery of new broadly cross-reactive/inhibitory antibodies targeting VAR2CSA.

U2 - 10.1128/mSphere.00391-21

DO - 10.1128/mSphere.00391-21

M3 - Comment/debate

C2 - 34047650

VL - 6

JO - mSphere

JF - mSphere

SN - 2379-5042

IS - 3

M1 - e00391-21

ER -

ID: 270718194