Genetic spatiotemporal anatomy of Plasmodium vivax malaria episodes in Greece, 2009-2013

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Genetic spatiotemporal anatomy of Plasmodium vivax malaria episodes in Greece, 2009-2013. / MALWEST Project.

In: Emerging Infectious Diseases , Vol. 24, No. 3, 03.2018, p. 541-548.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

MALWEST Project 2018, 'Genetic spatiotemporal anatomy of Plasmodium vivax malaria episodes in Greece, 2009-2013', Emerging Infectious Diseases , vol. 24, no. 3, pp. 541-548. https://doi.org/10.3201/eid2403.170605

APA

MALWEST Project (2018). Genetic spatiotemporal anatomy of Plasmodium vivax malaria episodes in Greece, 2009-2013. Emerging Infectious Diseases , 24(3), 541-548. https://doi.org/10.3201/eid2403.170605

Vancouver

MALWEST Project. Genetic spatiotemporal anatomy of Plasmodium vivax malaria episodes in Greece, 2009-2013. Emerging Infectious Diseases . 2018 Mar;24(3):541-548. https://doi.org/10.3201/eid2403.170605

Author

MALWEST Project. / Genetic spatiotemporal anatomy of Plasmodium vivax malaria episodes in Greece, 2009-2013. In: Emerging Infectious Diseases . 2018 ; Vol. 24, No. 3. pp. 541-548.

Bibtex

@article{ba8cedadaba74c7a8bc3bfa3e09a1ee9,
title = "Genetic spatiotemporal anatomy of Plasmodium vivax malaria episodes in Greece, 2009-2013",
abstract = "An influx of immigrants is contributing to the reemergence of Plasmodium vivax malaria in Greece; 1 persistent focus of transmission is in Laconia, Pelop{\'o}nnese. We genotyped archived blood samples from a substantial proportion of malaria cases recorded in Greece in 2009-2013 using 8 microsatellite markers and a PvMSP-3α gene fragment and plotted their spatiotemporal distribution. High parasite genetic diversity with low multiplicity of infection was observed. A subset of genetically identical/related parasites was restricted to 3 areas in migrants and Greek residents, with some persisting over 2 consecutive transmission periods. We identified 2 hitherto unsuspected additional foci of local transmission: Kardh{\'i}tsa and Attica. Furthermore, this analysis indicates that several cases in migrants initially classified as imported malaria were actually locally acquired. This study shows the potential for P. vivax to reestablish transmission and counsels public health authorities about the need for vigilance to achieve or maintain sustainable malaria elimination.",
author = "Gregory Spanakos and Georges Snounou and Danai Pervanidou and Michael Alifrangis and Anna Rosanas-Urgell and Agoritsa Baka and Maria Tseroni and Annita Vakali and Evdokia Vassalou and Eleni Patsoula and Herve Zeller and {Van Bortel}, Wim and Christos Hadjichristodoulou and {MALWEST Project}",
year = "2018",
month = mar,
doi = "10.3201/eid2403.170605",
language = "English",
volume = "24",
pages = "541--548",
journal = "Emerging Infectious Diseases",
issn = "1080-6040",
publisher = "CDC Centers for Disease Control and Prevention",
number = "3",

}

RIS

TY - JOUR

T1 - Genetic spatiotemporal anatomy of Plasmodium vivax malaria episodes in Greece, 2009-2013

AU - Spanakos, Gregory

AU - Snounou, Georges

AU - Pervanidou, Danai

AU - Alifrangis, Michael

AU - Rosanas-Urgell, Anna

AU - Baka, Agoritsa

AU - Tseroni, Maria

AU - Vakali, Annita

AU - Vassalou, Evdokia

AU - Patsoula, Eleni

AU - Zeller, Herve

AU - Van Bortel, Wim

AU - Hadjichristodoulou, Christos

AU - MALWEST Project

PY - 2018/3

Y1 - 2018/3

N2 - An influx of immigrants is contributing to the reemergence of Plasmodium vivax malaria in Greece; 1 persistent focus of transmission is in Laconia, Pelopónnese. We genotyped archived blood samples from a substantial proportion of malaria cases recorded in Greece in 2009-2013 using 8 microsatellite markers and a PvMSP-3α gene fragment and plotted their spatiotemporal distribution. High parasite genetic diversity with low multiplicity of infection was observed. A subset of genetically identical/related parasites was restricted to 3 areas in migrants and Greek residents, with some persisting over 2 consecutive transmission periods. We identified 2 hitherto unsuspected additional foci of local transmission: Kardhítsa and Attica. Furthermore, this analysis indicates that several cases in migrants initially classified as imported malaria were actually locally acquired. This study shows the potential for P. vivax to reestablish transmission and counsels public health authorities about the need for vigilance to achieve or maintain sustainable malaria elimination.

AB - An influx of immigrants is contributing to the reemergence of Plasmodium vivax malaria in Greece; 1 persistent focus of transmission is in Laconia, Pelopónnese. We genotyped archived blood samples from a substantial proportion of malaria cases recorded in Greece in 2009-2013 using 8 microsatellite markers and a PvMSP-3α gene fragment and plotted their spatiotemporal distribution. High parasite genetic diversity with low multiplicity of infection was observed. A subset of genetically identical/related parasites was restricted to 3 areas in migrants and Greek residents, with some persisting over 2 consecutive transmission periods. We identified 2 hitherto unsuspected additional foci of local transmission: Kardhítsa and Attica. Furthermore, this analysis indicates that several cases in migrants initially classified as imported malaria were actually locally acquired. This study shows the potential for P. vivax to reestablish transmission and counsels public health authorities about the need for vigilance to achieve or maintain sustainable malaria elimination.

U2 - 10.3201/eid2403.170605

DO - 10.3201/eid2403.170605

M3 - Journal article

C2 - 29460743

VL - 24

SP - 541

EP - 548

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

SN - 1080-6040

IS - 3

ER -

ID: 199300538