Thor Grundtvig Theander

Thor Grundtvig Theander

Professor

Member of:

  • CMP-BIOENGINEERING


  1. 2017
  2. Published

    A VAR2CSA:CSP conjugate capable of inducing dual specificity antibody responses

    Matondo, S., Thrane, Susan, Janitzek, C. M., Kavishe, R. A., Mwakalinga, S. B., Theander, Thor Grundtvig, Salanti, Ali, Nielsen, Morten Agertoug & Sander, Adam F. , 2017, In: African Health Sciences. 17, 2, p. 373-381 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Burkitt lymphoma expresses oncofetal chondroitin sulfate without being a reservoir for placental malaria sequestration

    Agerbaek, M. Ø., Bento Ayres Pereira, M. M., Clausen, T. M., Pehrson, C., Oo, H. Z., Spliid, C., Rich, J. R., Fung, V., Nkrumah, F., Neequaye, J., Biggar, R. J., Reynolds, S. J., Tosato, G., Pullarkat, S. T., Ayers, L. W., Theander, T. G., Daugaard, M., Bhatia, K., Nielsen, M. A., Mbulaiteye, S. M. & 1 others, Salanti, Ali, 2017, In: International Journal of Cancer. 140, 7, p. 1597–1608 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Improving the malaria transmission-blocking activity of a Plasmodium falciparum 48/45 based vaccine antigen by SpyTag/SpyCatcher mediated virus-like display

    Singh, S. K., Thrane, Susan, Janitzek, C. M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Theisen, Michael, Salanti, Ali & Sander, Adam F. , 2017, In: Vaccine. 35, 30, p. 3726-3732 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Parasites causing cerebral falciparum malaria bind multiple endothelial receptors and express EPCR and ICAM-1-binding PfEMP1

    Tuikue Ndam, N., Moussiliou, A., Lavstsen, Thomas, Kamaliddin, C., Jensen, Anja Ramstedt, Mama, A., Tahar, R., Wang, Christian William, Jespersen, Jakob Schmidt, Alao, J. M., Gamain, B., Theander, Thor Grundtvig & Deloron, P., 2017, In: The Journal of Infectious Diseases. 215, 12, p. 1918-1925 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Pre-clinical and clinical development of the first placental malaria vaccine

    Pehrson, Caroline, Salanti, Ali, Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2017, In: Expert Review of Vaccines. 16, 6, p. 613-624 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The Severity of Plasmodium falciparum infection is associated with transcript levels of var genes encoding endothelial protein C receptor-binding P. falciparum erythrocyte membrane protein 1

    Mkumbaye, S. I., Wang, Christian William, Lyimo, E., Jespersen, Jakob Schmidt, Manjurano, A., Mosha, J., Kavishe, R. A., Mwakalinga, S. B., Minja, D. T. R., Lusingu, J. P., Theander, Thor Grundtvig & Lavstsen, Thomas, 2017, In: Infection and Immunity. 85, 4, 14 p., 4e00841-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2016
  9. Published

    Oncofetal chondroitin sulfate glycosaminoglycans are key players in integrin signaling and tumor cell motility

    Clausen, Thomas Mandel, Bento Ayres Pereira, M. M., Al Nakouzi, N., Oo, H. Z., Agerbæk, Mette Ørskov, Lee, S., Ørum-Madsen, M. S., Kristensen, A. R., El-Naggar, A., Grandgenett, P. M., Grem, J. L., Hollingsworth, M. A., Holst, Peter Johannes, Theander, Thor Grundtvig, Sorensen, P. H., Daugaard, M. & Salanti, Ali, Dec 2016, In: Molecular Cancer Research. 14, 12, p. 1288-1299 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Bacterial superglue generates a full-length circumsporozoite protein virus-like particle vaccine capable of inducing high and durable antibody responses

    Janitzek, C. M., Matondo, S., Thrane, Susan, Nielsen, Morten Agertoug, Kavishe, R., Mwakalinga, S. B., Theander, Thor Grundtvig, Salanti, Ali & Sander, Adam F. , 8 Nov 2016, In: Malaria Journal. 15, 9 p., 545.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Plasma Ang2 and ADAM17 levels are elevated during clinical malaria; Ang2 level correlates with severity and expression of EPCR-binding PfEMP1

    Petersen, J. E. V., Mkumbaye, S. I., Vaaben, A. V., Manjurano, A., Lyimo, E., Kavishe, R. A., Mwakalinga, S. B., Mosha, J., Minja, D. T. R., Lusingu, J. P. A., Theander, Thor Grundtvig, Lavstsen, Thomas & Wang, Christian William, 27 Oct 2016, In: Scientific Reports. 6, 9 p., 35950.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Placental sequestration of Plasmodium falciparum malaria parasites is mediated by the interaction between VAR2CSA and chondroitin sulfate A on syndecan-1

    Ayres Pereira, M., Clausen, Thomas Mandel, Pehrson, Caroline, Mao, Y., Resende, M., Daugaard, M., Riis Kristensen, A., Spliid, C. B., Mathiesen, Line, Knudsen, Lisbeth E., Damm, Peter, Theander, Thor Grundtvig, R Hansson, S., Nielsen, Morten Agertoug & Salanti, Ali, Aug 2016, In: P L o S Pathogens. 12, 8, 26 p., e1005831.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Real-time and label free determination of ligand binding-kinetics to primary cancer tissue specimens; a novel tool for the assessment of biomarker targeting

    Clausen, Thomas Mandel, Ayres Pereira, M., Oo, H. Z., Resende, M., Gustavsson, Tobias, Mao, Y., Sugiura, N., Liew, J., Fazli, L., Theander, Thor Grundtvig, Daugaard, M. & Salanti, Ali, Jul 2016, In: Sensing and Bio-Sensing Research. 9, p. 23-30 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Adhesion of Plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue: a novel model of placental malaria

    Pehrson, Caroline, Mathiesen, Line, Heno, K. K., Salanti, Ali, dos Santos Marques Resende, M., Dzikowski, R., Damm, Peter, Hansson, S. R., King, C. L., Schneider, H., Wang, Christian William, Lavstsen, Thomas, Theander, Thor Grundtvig, Knudsen, Lisbeth E. & Nielsen, Morten Agertoug, 26 May 2016, In: Malaria Journal. 15, 12 p., 292.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Bacterial superglue enables easy development of efficient virus-like particle based vaccines

    Thrane, Susan, Janitzek, C. M., Matondo, S., dos Santos Marques Resende, M., Gustavsson, Tobias, De Jongh, W. A., Clemmensen, S., Roeffen, W., van de Vegte-Bolmer, M., van Gemert, G. J., Sauerwein, R., Schiller, J. T., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Salanti, Ali & Sander, Adam F. , 27 Apr 2016, In: Journal of Nanobiotechnology. 14, 16 p., 30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Plasmodium falciparum var genes expressed in children with severe malaria encode CIDRα1 domains

    Jespersen, Jakob Schmidt, Wang, Christian William, Mkumbaye, S. I., Minja, D. T., Petersen, Bent, Turner, Louise, Petersen, J. E., Lusingu, J. P., Theander, Thor Grundtvig & Lavstsen, Thomas, 2016, In: EMBO Molecular Medicine. 8, 8, p. 839-850 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Differences in PfEMP1s recognized by antibodies from patients with uncomplicated or severe malaria

    Duffy, M. F., Noviyanti, R., Tsuboi, T., Feng, Z., Trianty, L., Sebayang, B. F., Takashima, E., Sumardy, F., Lampah, D. A., Turner, Louise, Lavstsen, Thomas, Fowkes, F. J. I., Siba, P., Rogerson, S. J., Theander, Thor Grundtvig, Marfurt, J., Price, R. N., Anstey, N. M., Brown, G. V. & Papenfuss, A. T., 2016, In: Malaria Journal. 15, 12 p., 258.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2015
  19. Published

    Protein C system defects inflicted by the malaria parasite protein PfEMP1 can be overcome by a soluble EPCR variant

    Petersen, J. E. V., Bouwens, E. A. M., Tamayo, I., Turner, Louise, Wang, Christian William, Stins, M., Theander, Thor Grundtvig, Hermida, J., Mosnier, L. O. & Lavstsen, Thomas, Nov 2015, In: Thrombosis and Haemostasis. 114, 5, p. 1038-48 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    IgG antibodies to endothelial protein C receptor-binding Cysteine-rich interdomain region domains of Plasmodium falciparum erythrocyte membrane protein 1 are acquired early in life in individuals exposed to malaria

    Turner, Louise, Lavstsen, Thomas, Mmbando, B. P., Wang, Christian William, Magistrado, P. A., Vestergaard, L. S., Ishengoma, D. S., Minja, D. T. R., Lusingu, J. P. & Theander, Thor Grundtvig, Aug 2015, In: Infection and Immunity. 83, 8, p. 3096-103 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial

    RTS,S Clinical Trials Partnership, R. C. T. P., 4 Jul 2015, In: Lancet. 386, 9988, p. 31-45 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Structural Conservation Despite Huge Sequence Diversity Allows EPCR Binding by the PfEMP1 Family Implicated in Severe Childhood Malaria

    Lau, C. K. Y., Turner, Louise, Jespersen, Jakob Schmidt, Lowe, E. D., Petersen, Bent, Wang, Christian William, Petersen, J. E. V., Lusingu, J., Theander, Thor Grundtvig, Lavstsen, Thomas & Higgins, M. K., 14 Jan 2015, In: Cell Host & Microbe. 17, 1, p. 118-29 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    A novel virus-like particle based vaccine platform displaying the placental malaria antigen VAR2CSA

    Thrane, Susan, Janitzek, C. M., Agerbæk, Mette Ørskov, Ditlev, S. B., dos Santos Marques Resende, M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Salanti, Ali & Sander, Adam F. , 2015, In: PloS one. 10, 11, 16 p., e0143071.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine

    Neafsey, D. E., Juraska, M., Bedford, T., Benkeser, D., Valim, C., Griggs, A., Lievens, M., Abdulla, S., Adjei, S., Agbenyega, T., Agnandji, S. T., Aide, P., Anderson, S., Ansong, D., Aponte, J. J., Asante, K. P., Bejon, P., Birkett, A. J., Bruls, M., Connolly, K. M. & 43 others, D'Alessandro, U., Dobaño, C., Gesase, S., Greenwood, B., Grimsby, J., Tinto, H., Hamel, M. J., Hoffman, I., Kamthunzi, P., Kariuki, S., Kremsner, P. G., Leach, A., Lell, B., Lennon, N. J., Lusingu, J., Marsh, K., Martinson, F., Molel, J. T., Moss, E. L., Njuguna, P., Ockenhouse, C. F., Ogutu, B. R., Otieno, W., Otieno, L., Otieno, K., Owusu-Agyei, S., Park, D. J., Pellé, K., Robbins, D., Russ, C., Ryan, E. M., Sacarlal, J., Sogoloff, B., Sorgho, H., Tanner, M., Theander, Thor Grundtvig, Valea, I., Volkman, S. K., Yu, Q., Lapierre, D., Birren, B. W., Gilbert, P. B. & Wirth, D. F., 2015, In: New England Journal of Medicine. 373, 21, p. 2025-37 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania

    Hansson, Helle Smedegaard, Turner, Louise, Møller, L., Wang, Christian William, Minja, D., Gesase, S., Mmbando, B., Bygbjerg, Ib Christian, Theander, Thor Grundtvig, Lusingu, J. P. A., Alifrangis, Michael & Lavstsen, Thomas, 2015, In: Malaria Journal. 14, 9 p., 474.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Kompendium i mikrobiologi og infektionsmedicin

    Høiby, N., Skinhøj, P., Andersen, Å. B., Andersen, Leif Percival, Arendrup, M. C., Christiansen, C. B., Ciofu, Oana, Gerstoft, Jan, Johansen, Helle Krogh, Kemp, M., Kurtzhals, Jørgen, Nielsen, L. P., Lyngsøe Svejgaard, E., Theander, Thor Grundtvig & Thomsen, Allan Randrup, 2015, 1. ed. FADL's Forlag.

    Research output: Book/ReportBookEducation

  27. Published

    Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein

    Salanti, A., Clausen, T. M., Agerbæk, M. Ø., Al Nakouzi, N., Dahlbäck, M., Oo, H. Z., Lee, S., Gustavsson, T., Rich, J. R., Hedberg, B. J., Mao, Y., Barington, L., Pereira, M. A., LoBello, J., Endo, M., Fazli, L., Soden, J., Wang, C. K., Sander, A. F., Dagil, R. & 15 others, Thrane, Susan, Holst, Peter Johannes, Meng, L., Favero, F., Weiss, G. J., Nielsen, Morten Agertoug, Freeth, J., Nielsen, T. O., Zaia, J., Tran, N. L., Trent, J., Babcook, J. S., Theander, Thor Grundtvig, Sorensen, P. H. & Daugaard, M., 2015, In: Cancer Cell. 28, 4, p. 500-14 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    The Influence of Sub-Unit Composition and Expression System on the Functional Antibody Response in the Development of a VAR2CSA Based Plasmodium falciparum Placental Malaria Vaccine

    Nielsen, M. A., dos Santos Marques Resende, M., de Jongh, W. A., Ditlev, S. B., Mordmüller, B., Houard, S., Ndam, N. T., Agerbæk, M. Ø., Jensen, M. H., Massougbodji, A., Issifou, S., Strøbæk, A., Poulsen, L., Leroy, O., Kremsner, P. G., Chippaux, J-P., Luty, A. J. F., Deloron, P., Theander, T. G., Dyring, C. & 1 others, Salanti, Ali, 2015, In: PloS one. 10, 9, 12 p., e0135406.

    Research output: Contribution to journalJournal articleResearchpeer-review

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