Thor Grundtvig Theander
Professor
Centre for Medical Parasitology
Blegdamsvej 3, 2200 København N, Building: 07-11-17
CMP
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-11-TR4
Member of:
CMP-BIOENGINEERING
- 2017
- Published
A VAR2CSA:CSP conjugate capable of inducing dual specificity antibody responses
Matondo, S., Thrane, Susan, Janitzek, C. M., Kavishe, R. A., Mwakalinga, S. B., Theander, Thor Grundtvig, Salanti, Ali, Nielsen, Morten Agertoug & Sander, Adam F. , 2017, In: African Health Sciences. 17, 2, p. 373-381 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Burkitt lymphoma expresses oncofetal chondroitin sulfate without being a reservoir for placental malaria sequestration
Agerbaek, M. Ø., Bento Ayres Pereira, M. M., Clausen, T. M., Pehrson, C., Oo, H. Z., Spliid, C., Rich, J. R., Fung, V., Nkrumah, F., Neequaye, J., Biggar, R. J., Reynolds, S. J., Tosato, G., Pullarkat, S. T., Ayers, L. W., Theander, T. G., Daugaard, M., Bhatia, K., Nielsen, M. A., Mbulaiteye, S. M. & 1 others, , 2017, In: International Journal of Cancer. 140, 7, p. 1597–1608 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improving the malaria transmission-blocking activity of a Plasmodium falciparum 48/45 based vaccine antigen by SpyTag/SpyCatcher mediated virus-like display
Singh, S. K., Thrane, Susan, Janitzek, C. M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Theisen, Michael, Salanti, Ali & Sander, Adam F. , 2017, In: Vaccine. 35, 30, p. 3726-3732 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Parasites causing cerebral falciparum malaria bind multiple endothelial receptors and express EPCR and ICAM-1-binding PfEMP1
Tuikue Ndam, N., Moussiliou, A., Lavstsen, Thomas, Kamaliddin, C., Jensen, Anja Ramstedt, Mama, A., Tahar, R., Wang, Christian William, Jespersen, Jakob Schmidt, Alao, J. M., Gamain, B., Theander, Thor Grundtvig & Deloron, P., 2017, In: The Journal of Infectious Diseases. 215, 12, p. 1918-1925 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pre-clinical and clinical development of the first placental malaria vaccine
Pehrson, Caroline, Salanti, Ali, Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2017, In: Expert Review of Vaccines. 16, 6, p. 613-624 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Severity of Plasmodium falciparum infection is associated with transcript levels of var genes encoding endothelial protein C receptor-binding P. falciparum erythrocyte membrane protein 1
Mkumbaye, S. I., Wang, Christian William, Lyimo, E., Jespersen, Jakob Schmidt, Manjurano, A., Mosha, J., Kavishe, R. A., Mwakalinga, S. B., Minja, D. T. R., Lusingu, J. P., Theander, Thor Grundtvig & Lavstsen, Thomas, 2017, In: Infection and Immunity. 85, 4, 14 p., 4e00841-16.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Oncofetal chondroitin sulfate glycosaminoglycans are key players in integrin signaling and tumor cell motility
Clausen, Thomas Mandel, Bento Ayres Pereira, M. M., Al Nakouzi, N., Oo, H. Z., Agerbæk, Mette Ørskov, Lee, S., Ørum-Madsen, M. S., Kristensen, A. R., El-Naggar, A., Grandgenett, P. M., Grem, J. L., Hollingsworth, M. A., Holst, Peter Johannes, Theander, Thor Grundtvig, Sorensen, P. H., Daugaard, M. & Salanti, Ali, Dec 2016, In: Molecular Cancer Research. 14, 12, p. 1288-1299 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bacterial superglue generates a full-length circumsporozoite protein virus-like particle vaccine capable of inducing high and durable antibody responses
Janitzek, C. M., Matondo, S., Thrane, Susan, Nielsen, Morten Agertoug, Kavishe, R., Mwakalinga, S. B., Theander, Thor Grundtvig, Salanti, Ali & Sander, Adam F. , 8 Nov 2016, In: Malaria Journal. 15, 9 p., 545.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma Ang2 and ADAM17 levels are elevated during clinical malaria; Ang2 level correlates with severity and expression of EPCR-binding PfEMP1
Petersen, J. E. V., Mkumbaye, S. I., Vaaben, A. V., Manjurano, A., Lyimo, E., Kavishe, R. A., Mwakalinga, S. B., Mosha, J., Minja, D. T. R., Lusingu, J. P. A., Theander, Thor Grundtvig, Lavstsen, Thomas & Wang, Christian William, 27 Oct 2016, In: Scientific Reports. 6, 9 p., 35950.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Placental sequestration of Plasmodium falciparum malaria parasites is mediated by the interaction between VAR2CSA and chondroitin sulfate A on syndecan-1
Ayres Pereira, M., Clausen, Thomas Mandel, Pehrson, Caroline, Mao, Y., Resende, M., Daugaard, M., Riis Kristensen, A., Spliid, C. B., Mathiesen, Line, Knudsen, Lisbeth E., Damm, Peter, Theander, Thor Grundtvig, R Hansson, S., Nielsen, Morten Agertoug & Salanti, Ali, Aug 2016, In: P L o S Pathogens. 12, 8, 26 p., e1005831.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Real-time and label free determination of ligand binding-kinetics to primary cancer tissue specimens; a novel tool for the assessment of biomarker targeting
Clausen, Thomas Mandel, Ayres Pereira, M., Oo, H. Z., Resende, M., Gustavsson, Tobias, Mao, Y., Sugiura, N., Liew, J., Fazli, L., Theander, Thor Grundtvig, Daugaard, M. & Salanti, Ali, Jul 2016, In: Sensing and Bio-Sensing Research. 9, p. 23-30 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adhesion of Plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue: a novel model of placental malaria
Pehrson, Caroline, Mathiesen, Line, Heno, K. K., Salanti, Ali, dos Santos Marques Resende, M., Dzikowski, R., Damm, Peter, Hansson, S. R., King, C. L., Schneider, H., Wang, Christian William, Lavstsen, Thomas, Theander, Thor Grundtvig, Knudsen, Lisbeth E. & Nielsen, Morten Agertoug, 26 May 2016, In: Malaria Journal. 15, 12 p., 292.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bacterial superglue enables easy development of efficient virus-like particle based vaccines
Thrane, Susan, Janitzek, C. M., Matondo, S., dos Santos Marques Resende, M., Gustavsson, Tobias, De Jongh, W. A., Clemmensen, S., Roeffen, W., van de Vegte-Bolmer, M., van Gemert, G. J., Sauerwein, R., Schiller, J. T., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Salanti, Ali & Sander, Adam F. , 27 Apr 2016, In: Journal of Nanobiotechnology. 14, 16 p., 30.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasmodium falciparum var genes expressed in children with severe malaria encode CIDRα1 domains
Jespersen, Jakob Schmidt, Wang, Christian William, Mkumbaye, S. I., Minja, D. T., Petersen, Bent, Turner, Louise, Petersen, J. E., Lusingu, J. P., Theander, Thor Grundtvig & Lavstsen, Thomas, 2016, In: EMBO Molecular Medicine. 8, 8, p. 839-850 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differences in PfEMP1s recognized by antibodies from patients with uncomplicated or severe malaria
Duffy, M. F., Noviyanti, R., Tsuboi, T., Feng, Z., Trianty, L., Sebayang, B. F., Takashima, E., Sumardy, F., Lampah, D. A., Turner, Louise, Lavstsen, Thomas, Fowkes, F. J. I., Siba, P., Rogerson, S. J., Theander, Thor Grundtvig, Marfurt, J., Price, R. N., Anstey, N. M., Brown, G. V. & Papenfuss, A. T., 2016, In: Malaria Journal. 15, 12 p., 258.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Protein C system defects inflicted by the malaria parasite protein PfEMP1 can be overcome by a soluble EPCR variant
Petersen, J. E. V., Bouwens, E. A. M., Tamayo, I., Turner, Louise, Wang, Christian William, Stins, M., Theander, Thor Grundtvig, Hermida, J., Mosnier, L. O. & Lavstsen, Thomas, Nov 2015, In: Thrombosis and Haemostasis. 114, 5, p. 1038-48 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IgG antibodies to endothelial protein C receptor-binding Cysteine-rich interdomain region domains of Plasmodium falciparum erythrocyte membrane protein 1 are acquired early in life in individuals exposed to malaria
Turner, Louise, Lavstsen, Thomas, Mmbando, B. P., Wang, Christian William, Magistrado, P. A., Vestergaard, L. S., Ishengoma, D. S., Minja, D. T. R., Lusingu, J. P. & Theander, Thor Grundtvig, Aug 2015, In: Infection and Immunity. 83, 8, p. 3096-103 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial
RTS,S Clinical Trials Partnership, R. C. T. P., 4 Jul 2015, In: Lancet. 386, 9988, p. 31-45 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural Conservation Despite Huge Sequence Diversity Allows EPCR Binding by the PfEMP1 Family Implicated in Severe Childhood Malaria
Lau, C. K. Y., Turner, Louise, Jespersen, Jakob Schmidt, Lowe, E. D., Petersen, Bent, Wang, Christian William, Petersen, J. E. V., Lusingu, J., Theander, Thor Grundtvig, Lavstsen, Thomas & Higgins, M. K., 14 Jan 2015, In: Cell Host & Microbe. 17, 1, p. 118-29 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel virus-like particle based vaccine platform displaying the placental malaria antigen VAR2CSA
Thrane, Susan, Janitzek, C. M., Agerbæk, Mette Ørskov, Ditlev, S. B., dos Santos Marques Resende, M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Salanti, Ali & Sander, Adam F. , 2015, In: PloS one. 10, 11, 16 p., e0143071.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine
Neafsey, D. E., Juraska, M., Bedford, T., Benkeser, D., Valim, C., Griggs, A., Lievens, M., Abdulla, S., Adjei, S., Agbenyega, T., Agnandji, S. T., Aide, P., Anderson, S., Ansong, D., Aponte, J. J., Asante, K. P., Bejon, P., Birkett, A. J., Bruls, M., Connolly, K. M. & 43 others, , 2015, In: New England Journal of Medicine. 373, 21, p. 2025-37 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania
Hansson, Helle Smedegaard, Turner, Louise, Møller, L., Wang, Christian William, Minja, D., Gesase, S., Mmbando, B., Bygbjerg, Ib Christian, Theander, Thor Grundtvig, Lusingu, J. P. A., Alifrangis, Michael & Lavstsen, Thomas, 2015, In: Malaria Journal. 14, 9 p., 474.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kompendium i mikrobiologi og infektionsmedicin
Høiby, N., Skinhøj, P., Andersen, Å. B., Andersen, Leif Percival, Arendrup, M. C., Christiansen, C. B., Ciofu, Oana, Gerstoft, Jan, Johansen, Helle Krogh, Kemp, M., Kurtzhals, Jørgen, Nielsen, L. P., Lyngsøe Svejgaard, E., Theander, Thor Grundtvig & Thomsen, Allan Randrup, 2015, 1. ed. FADL's Forlag.Research output: Book/Report › Book › Education
- Published
Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein
Salanti, A., Clausen, T. M., Agerbæk, M. Ø., Al Nakouzi, N., Dahlbäck, M., Oo, H. Z., Lee, S., Gustavsson, T., Rich, J. R., Hedberg, B. J., Mao, Y., Barington, L., Pereira, M. A., LoBello, J., Endo, M., Fazli, L., Soden, J., Wang, C. K., Sander, A. F., Dagil, R. & 15 others, , 2015, In: Cancer Cell. 28, 4, p. 500-14 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Influence of Sub-Unit Composition and Expression System on the Functional Antibody Response in the Development of a VAR2CSA Based Plasmodium falciparum Placental Malaria Vaccine
Nielsen, M. A., dos Santos Marques Resende, M., de Jongh, W. A., Ditlev, S. B., Mordmüller, B., Houard, S., Ndam, N. T., Agerbæk, M. Ø., Jensen, M. H., Massougbodji, A., Issifou, S., Strøbæk, A., Poulsen, L., Leroy, O., Kremsner, P. G., Chippaux, J-P., Luty, A. J. F., Deloron, P., Theander, T. G., Dyring, C. & 1 others, , 2015, In: PloS one. 10, 9, 12 p., e0135406.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11256
Most downloads
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745
downloads
Real-time and label free determination of ligand binding-kinetics to primary cancer tissue specimens; a novel tool for the assessment of biomarker targeting
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
560
downloads
Bacterial superglue enables easy development of efficient virus-like particle based vaccines
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
508
downloads
Placental sequestration of Plasmodium falciparum malaria parasites is mediated by the interaction between VAR2CSA and chondroitin sulfate A on syndecan-1
Research output: Contribution to journal › Journal article › Research › peer-review
Published