Thor Grundtvig Theander
Professor
Centre for Medical Parasitology
Blegdamsvej 3, 2200 København N, Building: 07-11-17
CMP
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-11-TR4
Member of:
CMP-BIOENGINEERING
- 2024
- Published
Anaemia in the first trimester and poor physiological plasma expansion during pregnancy negatively impact foetal weight and newborn anthropometrics: An observational cohort study in Tanzania
Schmiegelow, Christentze, Møller, S. L., Yde, A. M., Nielsen, B. B., Hjort, Line, Theander, Thor Grundtvig, Lusingu, J. P. A., Minja, D. T. R. & Bygbjerg, Ib Christian, 2024, In: Tropical Medicine & International Health. 29, 3, p. 243-255 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Contact allergens in African countries: A review of published patch test studies
Bonefeld, N. M., Menné, T., Ahrensbøll-Friis, U., Gadsbøll, A. S. Ø., Wang, Christian William, Theander, Thor Grundtvig, Masenga, E. J., Mavura, D., Ødum, Niels, Bonefeld, Charlotte Menne & Geisler, Carsten, 2024, In: Contact Dermatitis. 90, 2, p. 103-109Research output: Contribution to journal › Review › Research › peer-review
- E-pub ahead of print
Vulnerable newborn types: analysis of subnational, population-based birth cohorts for 541 285 live births in 23 countries, 2000–2021
Erchick, D. J., Hazel, E. A., Katz, J., Lee, A. C. C., Diaz, M., Wu, L. S. F., Yoshida, S., Bahl, R., Grandi, C., Labrique, A. B., Rashid, M., Ahmed, S., Roy, A. D., Haque, R., Shaikh, S., Baqui, A. H., Saha, S. K., Khanam, R., Rahman, S., Shapiro, R. & 30 others, , 2024, (E-pub ahead of print) In: BJOG: An International Journal of Obstetrics and Gynaecology.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Aotus nancymaae model predicts human immune response to the placental malaria vaccine candidate VAR2CSA
Doritchamou, J., Nielsen, M. A., Chêne, A., Viebig, N. K., Lambert, L. E., Sander, A. F., Semblat, J. P., Hundt, S., Orr-Gonzalez, S., Janitzek, C. M., Spiegel, A. J., Clemmensen, S. B., Thomas, M. L., Nason, M. C., Snow-Smith, M., Barnafo, E. K., Shiloach, J., Chen, B. B., Nadakal, S., Highsmith, K. & 15 others, , 2023, In: Lab Animal. 52, 12, p. 315-323Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A cVLP-based vaccine displaying full-length PCSK9 elicits a higher reduction in plasma PCSK9 than similar peptide-based cVLP vaccines
Goksøyr, L., Skrzypczak, M., Sampson, M., Nielsen, Morten Agertoug, Salanti, Ali, Theander, Thor Grundtvig, Remaley, A. T., Jongh, W. A. D. & Sander, Adam F. , 2023, In: Vaccines. 11, 1, 2.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bispecific T cell-engager targeting oncofetal chondroitin sulfate induces complete tumor regression and protective immune memory in mice
Skeltved, Nanna, Nordmaj, Mie Anemone, Pagh-Berendtsen, Nicolai, Dagil, Robert, Stormer, E. M. R., Al-Nakouzi, N., Jiang, K., Aicher, A., Heeschen, C., Gustavsson, Tobias, Choudhary, Swati, Gögenur, Ismail, Christensen, Jan Pravsgaard, Theander, Thor Grundtvig, Daugaard, M., Salanti, Ali & Nielsen, Morten Agertoug, 2023, In: Journal of Experimental & Clinical Cancer Research. 42, 16 p., 106.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative analysis of spike-specific IgG Fc glycoprofiles elicited by adenoviral, mRNA, and protein-based SARS-CoV-2 vaccines
Van Coillie, J., Pongracz, T., Šuštić, T., Wang, W., Nouta, J., Le Gars, M., Keijzer, S., Linty, F., Cristianawati, O., Keijser, J. B. D., Visser, R., van Vught, L. A., Slim, M. A., van Mourik, N., Smit, M. J., Sander, A., Schmidt, D. E., Steenhuis, M., Rispens, T., Nielsen, M. A. & 31 others, , 2023, In: iScience. 26, 9, p. 1-15 107619.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cord blood FGF-21 and GDF-15 levels are affected by maternal exposure to moderate to severe anemia and malaria
Hjort, Line, Albrechtsen, Nicolai Jacob Wewer, Minja, D., Rasmussen, C., Møller, S. L., Lusingu, J., Theander, Thor Grundtvig, Bygbjerg, Ib Christian, Schmiegelow, Christentze & Grunnet, Louise Groth, 2023, In: Journal of the Endocrine Society. 7, 10, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endothelial protein C receptor binding induces conformational changes to severe malaria-associated group A PfEMP1
Raghavan, Sai Sundar Rajan, Turner, Louise, Jensen, R. W., Johansen, Nicolai Tidemand, Jensen, D. S., Gourdon, Pontus Emanuel, Zhang, J., Wang, Y., Theander, Thor Grundtvig, Wang, Kaituo & Lavstsen, Thomas, 2023, In: Structure. 31, 10, p. 1174-1183.e4Research output: Contribution to journal › Journal article › Research › peer-review
- Published
First-in-human use of a modular capsid virus-like vaccine platform: An open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2
Smit, M. J., Sander, A. F., Ariaans, M. B. P. A., Fougeroux, C., Heinzel, C., Fendel, R., Esen, M., Kremsner, P. G., Ter Heine, R., Wertheim, H. F., Idorn, M., Paludan, S. R., Underwood, A. P., Binderup, A., Ramirez, S., Bukh, J., Soegaard, M., Erdogan, S. M., Gustavsson, T., Clemmensen, S. & 14 others, , 2023, In: The Lancet Microbe. 4, 3, p. e140-e148Research output: Contribution to journal › Journal article › Research › peer-review
- Accepted/In press
Neonatal mortality risk of vulnerable newborns: A descriptive analysis of subnational, population-based birth cohorts for 238 143 live births in low- and middle-income settings from 2000 to 2017
Hazel, E. A., Erchick, D. J., Katz, J., Lee, A. C. C., Diaz, M., Wu, L. S. F., West, K. P., Shamim, A. A., Christian, P., Ali, H., Baqui, A. H., Saha, S. K., Ahmed, S., Roy, A. D., Silveira, M. F., Buffarini, R., Shapiro, R., Zash, R., Kolsteren, P., Lachat, C. & 93 others, , 2023, (Accepted/In press) In: BJOG: An International Journal of Obstetrics and Gynaecology.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Freeze-Drying of a Capsid Virus-like Particle-Based Platform Allows Stable Storage of Vaccines at Ambient Temperature
Aves, Kara-Lee, Janitzek, C. M., Fougeroux, Cyrielle Elyette, Theander, Thor Grundtvig & Sander, Adam F. , 2022, In: Pharmaceutics. 14, 6, 1301.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mapping the cord blood transcriptome of pregnancies affected by early maternal anemia to identify signatures of fetal programming
Hatem, G., Hjort, Line, Asplund, O., Minja, D. T. R., Msemo, O. A., Møller, S. L., Lavstsen, Thomas, Grunnet, Louise Groth, Lusingu, J. P. A., Hansson, O., Christensen, Dirk Lund, Vaag, Allan, Artner, I., Theander, Thor Grundtvig, Groop, L., Schmiegelow, Christentze, Bygbjerg, Ib Christian & Prasad, R. B., 2022, In: The Journal of clinical endocrinology and metabolism. 107, 5, p. 1303–1316 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preclinical Efficacy of a Capsid Virus-like Particle-Based Vaccine Targeting IL-1β for Treatment of Allergic Contact Dermatitis
Goksøyr, L., Funch, Anders Boutrup, Okholm, A. K., Theander, Thor Grundtvig, de Jongh, W. A., Bonefeld, Charlotte Menne & Sander, Adam F. , 2022, In: Vaccines. 10, 5, 828.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The choice of reference chart affects the strength of the association between malaria in pregnancy and small for gestational age: an individual participant data meta-analysis comparing the Intergrowth-21 with a Tanzanian birthweight chart
Mtove, G., Minja, D. T. R., Abdul, O., Gesase, S., Maleta, K., Divala, T. H., Patson, N., Ashorn, U., Laufer, M. K., Madanitsa, M., Ashorn, P., Mathanga, D., Chinkhumba, J., Gutman, J. R., Ter Kuile, F. O., Møller, S. L., Bygbjerg, I. C., Alifrangis, M., Theander, T., Lusingu, J. P. A. & 1 others, , 2022, In: Malaria Journal. 21, 1, 12 p., 292.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two-component vaccine consisting of virus-like particles displaying hepatitis C virus envelope protein 2 oligomers
Prentø, Jannick, Janitzek, C. M., Velázquez-Moctezuma, R., Sørensen, Andreas Holst Holmegaard, Jørgensen, T., Clemmensen, S., Soroka, V., Thrane, Susan, Theander, Thor Grundtvig, Nielsen, Morten Agertoug, Salanti, Ali, Bukh, Jens & Sander, Adam F. , 2022, In: npj Vaccines. 7, 148.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Head-to-head comparison of modular vaccines developed using different capsid virus-like particle backbones and antigen conjugation systems
Fredsgaard, L., Goksøyr, L., Thrane, Susan, Aves, Kara-Lee, Theander, Thor Grundtvig & Sander, Adam F. , Jun 2021, In: Vaccines. 9, 6, 11 p., 539.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity
Fougeroux, C., Goksøyr, L., Idorn, M., Soroka, V., Myeni, S. K., Dagil, R., Janitzek, C. M., Søgaard, M., Aves, K-L., Horsted, E. W., Erdogan, S. M., Gustavsson, T., Dorosz, J., Clemmensen, S., Fredsgaard, L., Thrane, S., Vidal-Calvo, E. E., Khalifé, P., Hulen, T. M., Choudhary, S. & 27 others, , 2021, In: Nature Communications. 12, 1, p. 324Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding
Wang, Kaituo, Dagil, Robert, Lavstsen, Thomas, Misra, S. K., Spliid, C. B., Wang, Y., Gustavsson, Tobias, Sandoval, D. R., Vidal-Calvo, E. E., Choudhary, Swati, Agerbæk, Mette Ørskov, Lindorff-Larsen, Kresten, Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sharp, J. S., Clausen, Thomas Mandel, Gourdon, Pontus Emanuel & Salanti, Ali, 2021, In: Nature Communications. 12, 1, 10 p., 2956.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection of VAR2CSA‐captured colorectal cancer cells from blood samples by real‐time reverse transcription PCR
Bang‐christensen, S. R., Katerov, V., Jørgensen, Amalie Mundt, Gustavsson, Tobias, Choudhary, Swati, Theander, Thor Grundtvig, Salanti, Ali, Allawi, H. T. & Agerbæk, Mette Ørskov, 2021, In: Cancers. 13, 23, 5881.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a bispecific immune engager using a recombinant malaria protein
Nordmaj, Mie Anemone, Roberts, M. E., Sachse, E. S., Dagil, Robert, Andersen, Anne Poder, Skeltved, Nanna, Grunddal, Kaare Villum, Erdogan, Sayit Mahmut, Choudhary, Swati, Gustavsson, Tobias, Ørum-madsen, M. S., Moskalev, I., Tian, W., Yang, Zhang, Clausen, Thomas Mandel, Theander, Thor Grundtvig, Daugaard, M., Nielsen, Morten Agertoug & Salanti, Ali, 2021, In: Cell Death & Disease. 12, 4, 11 p., 353.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced birth weight caused by sextuple drug resistant Plasmodium falciparum infection in early second trimester
Hansson, Helle Smedegaard, Minja, D. T. R., Moeller, S. L., Lusingu, J. P. A., Bygbjerg, Ib Christian, Yde, A., Jensen, R. W., Nag, S., Msemo, O. A., Theander, Thor Grundtvig, Alifrangis, Michael & Schmiegelow, Christentze, 2021, In: The Journal of Infectious Diseases. 224, 9, p. 1605–1613Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The immunogenicity of capsid-like particle vaccines in combination with different adjuvants using different routes of administration
Janitzek, C. M., Carlsen, P. H. R., Thrane, Susan, Khanna, V. M., Jakob, V., Barnier-Quer, C., Collin, N., Theander, Thor Grundtvig, Salanti, Ali, Nielsen, Morten Agertoug & Sander, Adam F. , 2021, In: Vaccines. 9, 2, 131.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The specificity of the malarial VAR2CSA protein for chondroitin sulfate depends on 4-O-sulfation and ligand accessibility
Spliid, C. B., Toledo, A. G., Sanderson, P., Mao, Y., Gatto, F., Gustavsson, Tobias, Choudhary, Swati, Saldanha, A. L., Vogelsang, R. P., Gögenur, Ismail, Theander, Thor Grundtvig, Leach, F. E., Amster, I. J., Esko, J. D., Salanti, Ali & Clausen, Thomas Mandel, 2021, In: The Journal of Biological Chemistry. 297, 6, 15 p., 101391.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
In vivo imaging of the buccal mucosa shows loss of the endothelial glycocalyx and perivascular hemorrhages in pediatric Plasmodium falciparum malaria
Lyimo, E., Haslund, L. E., Ramsing, T., Wang, Christian William, Efunshile, A. M., Manjurano, A., Makene, V., Lusingu, J., Theander, Thor Grundtvig, Kurtzhals, Jørgen, Paulsen, R. & Hempel, C., 2020, In: Infection and Immunity. 88, 3, e00679-19.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11256
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Real-time and label free determination of ligand binding-kinetics to primary cancer tissue specimens; a novel tool for the assessment of biomarker targeting
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
557
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Bacterial superglue enables easy development of efficient virus-like particle based vaccines
Research output: Contribution to journal › Journal article › Research › peer-review
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506
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Placental sequestration of Plasmodium falciparum malaria parasites is mediated by the interaction between VAR2CSA and chondroitin sulfate A on syndecan-1
Research output: Contribution to journal › Journal article › Research › peer-review
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