Robert Dagil

Robert Dagil

Assistant Professor

Member of:

  • VAR2CSA team

  • CMP-BIOENGINEERING

ORCID: 0000-0002-5594-0716

Publication year:
All
1 - 22 out of 22Page size: 25
  1. 2023
  2. Published

    Bispecific T cell-engager targeting oncofetal chondroitin sulfate induces complete tumor regression and protective immune memory in mice

    Skeltved, Nanna, Nordmaj, Mie Anemone, Pagh-Berendtsen, Nicolai, Dagil, Robert, Stormer, E. M. R., Al-Nakouzi, N., Jiang, K., Aicher, A., Heeschen, C., Gustavsson, Tobias, Choudhary, Swati, Gögenur, Ismail, Christensen, Jan Pravsgaard, Theander, Thor Grundtvig, Daugaard, M., Salanti, Ali & Nielsen, Morten Agertoug, 2023, In: Journal of Experimental & Clinical Cancer Research. 42, 16 p., 106.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    First-in-human use of a modular capsid virus-like vaccine platform: An open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2

    Smit, M. J., Sander, A. F., Ariaans, M. B. P. A., Fougeroux, C., Heinzel, C., Fendel, R., Esen, M., Kremsner, P. G., Ter Heine, R., Wertheim, H. F., Idorn, M., Paludan, S. R., Underwood, A. P., Binderup, A., Ramirez, S., Bukh, J., Soegaard, M., Erdogan, S. M., Gustavsson, T., Clemmensen, S. & 14 others, Theander, Thor Grundtvig, Salanti, Ali, Hamborg, M., de Jongh, W. A., McCall, M. B. B., Nielsen, Morten Agertoug, Mordmüller, B. G., COUGH-1 trial study group, C. T. S. G., Dagil, Robert, Goksøyr, L., Hulen, T. M., Brygger, C. M. J., Khalifé, P. K. & Vidal-Calvo, E. E., 2023, In: The Lancet Microbe. 4, 3, p. e140-e148

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Intrinsically Disordered Proteins as an Instrument for Research-Integrating Teaching

    Skriver, K., Sjørup, S. A., Langkilde, A. E., Balouka, E., Christensen, C. S., Carbel, K., Decker, J. N. V., Essenbæk, D. N., Gräf, J. F., Jessen, C. H., Kristensen, P., Merrild, C., Mortensen, T. S., Nalepa, I. F., Nordsteen, B. W., Svoren, S. K., van Hall, M., Weicher, J., Wind, M. L., Zhang, D. & 8 others, Saar, Daniel, Blæsild, H., Stahlhut, M., Andersen, K. V., Dagil, Robert, Vestergaard, Bente, Ryberg, Marie L. & Kragelund, Birthe Brandt, 2023, In: The Biophysicist. 4 , 2, p. 1-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Malaria biomimetic for tumor targeted drug delivery

    Pihl, J., Clausen, T. M., Zhou, J., Krishnan, N., Ørum-Madsen, M. S., Gustavsson, Tobias, Dagil, Robert, Daugaard, M., Choudhary, Swati, Foged, Camilla, Esko, J. D., Zhang, L., Fang, R. H. & Salanti, Ali, 2023, In: ACS Nano. 17, 14, p. 13500–13509

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2022
  7. Published

    Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA

    Raghavan, Sai Sundar Rajan, Dagil, Robert, Lopez-Perez, Mary, Conrad, J., Bassi, Maria Rosaria, Quintana Varon, Maria del Pilar, Choudhary, Swati, Gustavsson, Tobias, Wang, Y., Gourdon, Pontus Emanuel, Ofori, M. F., Christensen, S. B., Minja, D. T. R., Schmiegelow, Christentze, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Hviid, Lars, Salanti, Ali, Lavstsen, Thomas & Wang, Kaituo, 2022, In: PLoS Pathogens. 18, 11, e1010924.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Internalization and trafficking of CSPG-bound recombinant VAR2CSA lectins in cancer cells

    Wang, Chris Kedong, Nelepcu, I., Hui, D., Oo, H. Z., Truong, S., Zhao, S., Tahiry, Z., Esfandnia, S., Ghaidi, F., Adomat, H., Dagil, Robert, Gustavsson, Tobias, Choudhary, Swati, Salanti, Ali, Sorensen, P. H., Al Nakouzi, N. & Daugaard, M., 2022, In: Scientific Reports. 12, 3075.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Reformation of the chondroitin sulfate glycocalyx enables progression of AR-independent prostate cancer

    Al Nakouzi, N., Wang, C. K., Oo, H. Z., Nelepcu, I., Lallous, N., Spliid, C. B., Khazamipour, N., Lo, J., Truong, S., Collins, C., Hui, D., Esfandnia, S., Adomat, H., Clausen, T. M., Gustavsson, T., Choudhary, S., Dagil, R., Corey, E., Wang, Y., Chauchereau, A. & 6 others, Fazli, L., Esko, J. D., Salanti, Ali, Nelson, P. S., Gleave, M. & Daugaard, M., 2022, In: Nature Communications. 13, 4760.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. The TH1 cell lineage-determining transcription factor T-bet suppresses TH2 gene expression by redistributing GATA3 away from TH2 genes

    Hertweck, A., Vila de Mucha, M., Barber, P. R., Dagil, Robert, Porter, H., Ramos, A., Lord, G. M. & Jenner, R. G., 2022, In: Nucleic Acids Research. 50, 8, p. 4557–4573

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. 2021
  12. Published

    Two-component nanoparticle vaccine displaying glycosylated spike S1 domain induces neutralizing antibody response against SARS-CoV-2 variants

    van Oosten, L., Altenburg, J. J., Fougeroux, C., Geertsema, C., van den End, F., Evers, W. A. C., Westphal, A. H., Lindhoud, S., van den Berg, W., Swarts, D. C., Deurhof, L., Suhrbier, A., Le, T. T., Torres Morales, S., Myeni, S. K., Kikkert, M., Sander, A. F., de Jongh, W. A., Dagil, R., Nielsen, M. A. & 9 others, Salanti, Ali, Søgaard, M., Keijzer, T. M. P., Weijers, D., Eppink, M. H. M., Wijffels, R. H., van Oers, M. M., Martens, D. E. & Pijlman, G. P., 26 Oct 2021, In: mBio. 12, 5, e0181321.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity

    Fougeroux, C., Goksøyr, L., Idorn, M., Soroka, V., Myeni, S. K., Dagil, R., Janitzek, C. M., Søgaard, M., Aves, K-L., Horsted, E. W., Erdogan, S. M., Gustavsson, T., Dorosz, J., Clemmensen, S., Fredsgaard, L., Thrane, S., Vidal-Calvo, E. E., Khalifé, P., Hulen, T. M., Choudhary, S. & 27 others, Theisen, Michael, Singh, S. K., Garcia-Senosiain, A., Van Oosten, L., Pijlman, G., Hierzberger, B., Domeyer, T., Nalewajek, B. W., Strøbæk, A., Skrzypczak, M., Andersson, L. F., Buus, Søren, Buus, Anette Stryhn, Christensen, Jan Pravsgaard, Dalebout, T. J., Iversen, Kasper, Harritshøj, L. H., Mordmüller, B., Ullum, H., Reinert, L. S., de Jongh, W. A., Kikkert, M., Paludan, S. R., Theander, Thor Grundtvig, Nielsen, Morten Agertoug, Salanti, Ali & Sander, Adam F. , 2021, In: Nature Communications. 12, 1, p. 324

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding

    Wang, Kaituo, Dagil, Robert, Lavstsen, Thomas, Misra, S. K., Spliid, C. B., Wang, Y., Gustavsson, Tobias, Sandoval, D. R., Vidal-Calvo, E. E., Choudhary, Swati, Agerbæk, Mette Ørskov, Lindorff-Larsen, Kresten, Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sharp, J. S., Clausen, Thomas Mandel, Gourdon, Pontus Emanuel & Salanti, Ali, 2021, In: Nature Communications. 12, 1, 10 p., 2956.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Development of a bispecific immune engager using a recombinant malaria protein

    Nordmaj, Mie Anemone, Roberts, M. E., Sachse, E. S., Dagil, Robert, Andersen, Anne Poder, Skeltved, Nanna, Grunddal, Kaare Villum, Erdogan, Sayit Mahmut, Choudhary, Swati, Gustavsson, Tobias, Ørum-madsen, M. S., Moskalev, I., Tian, W., Yang, Zhang, Clausen, Thomas Mandel, Theander, Thor Grundtvig, Daugaard, M., Nielsen, Morten Agertoug & Salanti, Ali, 2021, In: Cell Death & Disease. 12, 4, 11 p., 353.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Oncofetal chondroitin sulfate is a highly expressed therapeutic target in non-small cell lung cancer

    Oo, H. Z., Lohinai, Z., Khazamipour, N., Lo, J., Kumar, G., Pihl, J., Adomat, H., Nabavi, N., Behmanesh, H., Zhai, B., Dagil, R., Choudhary, S., Gustavsson, T., Clausen, T. M., Esko, J. D., Allen, J. W., Thompson, M. A., Tran, N. L., Moldvay, J., Dome, B. & 4 others, Salanti, Ali, Al-Nakouzi, N., Weiss, G. J. & Daugaard, M., 2021, In: Cancers. 13, 17, 16 p., 4489.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. 2019
  18. Published

    Capture and Detection of Circulating Glioma Cells Using the Recombinant VAR2CSA Malaria Protein

    Bang-Christensen, S. R., Pedersen, R. S., Pereira, M. A., Clausen, T. M., Løppke, C., Sand, N. T., Ahrens, T. D., Jørgensen, A. M., Lim, Y. C., Goksøyr, L., Choudhary, S., Gustavsson, T., Dagil, R., Daugaard, M., Sander, A. F., Torp, M. H., Søgaard, M., Theander, T. G., Østrup, O., Lassen, U. & 3 others, Hamerlik, P., Salanti, Ali & Agerbæk, Mette Ørskov, 2019, In: Cells. 8, 9, 21 p., 998.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties

    Dagil, Robert, Ball, N. J., Ogrodowicz, R. W., Hobor, F., Purkiss, A. G., Kelly, G., Martin, S. R., Taylor, I. A. & Ramos, A., 2019, In: Nucleic Acids Research. 47, 8, p. 4334-4348 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. 2015
  21. Published

    Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein

    Salanti, A., Clausen, T. M., Agerbæk, M. Ø., Al Nakouzi, N., Dahlbäck, M., Oo, H. Z., Lee, S., Gustavsson, T., Rich, J. R., Hedberg, B. J., Mao, Y., Barington, L., Pereira, M. A., LoBello, J., Endo, M., Fazli, L., Soden, J., Wang, C. K., Sander, A. F., Dagil, R. & 15 others, Thrane, Susan, Holst, Peter Johannes, Meng, L., Favero, F., Weiss, G. J., Nielsen, Morten Agertoug, Freeth, J., Nielsen, T. O., Zaia, J., Tran, N. L., Trent, J., Babcook, J. S., Theander, Thor Grundtvig, Sorensen, P. H. & Daugaard, M., 2015, In: Cancer Cell. 28, 4, p. 500-14 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. 2013
  23. Published

    Gentamicin binds to the megalin receptor as a competitive inhibitor using the common ligand binding motif of complement type repeats: insight from the nmr structure of the 10th complement type repeat domain alone and in complex with gentamicin

    Dagil, Robert, O'Shea, Charlotte, Nykjær, A., Bonvin, A. M. J. J. & Kragelund, Birthe Brandt, 2013, In: The Journal of Biological Chemistry. 288, 6, p. 4424-35 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    New horizons for lipoprotein receptors: communication by β-propellers

    Andersen, O. M., Dagil, Robert & Kragelund, Birthe Brandt, 2013, In: Journal of Lipid Research. 54, p. 2763-2774 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. 2012
  26. Published

    The WSXWS motif in cytokine receptors is a molecular switch involved in receptor activation: insight from structures of the prolactin receptor

    Dagil, Robert, Knudsen, M. J., Olsen, Johan Gotthardt, O'Shea, Charlotte, Franzmann, M., Goffin, V., Teilum, Kaare, Breinholt, J. & Kragelund, Birthe Brandt, 2012, In: Structure. 20, 2, p. 270-282 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. 2011
  28. Published

    Streptococcal pyogenic exotoxin B (SpeB) boosts the contact system via binding of a-1 antitrypsin

    Meinert Niclasen, L., Olsen, Johan Gotthardt, Dagil, Robert, Qing, Z., Sørensen, O. E. & Kragelund, Birthe Brandt, 2011, In: Biochemical Journal. 434, 1, p. 123-32 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. 2009
  30. Published

    Structure of the Mature Streptococcal Cysteine Protease Exotoxin mSpeB in Its Active Dimeric Form

    Olsen, Johan Gotthardt, Dagil, Robert, Niclasen, L. M., Sørensen, O. E. & Kragelund, Birthe Brandt, 2009, In: Journal of Molecular Biology. 393, 3, p. 693-703 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 2006
  32. Published

    On the use of pseudocontact shifts in the structure determination of metalloproteins

    Jensen, M. R., Hansen, D. F., Ayna, U., Dagil, Robert, Hass, S. A. M., Christensen, H. E. M. & Led, J. J., 2006, In: Magnetic Resonance in Chemistry. 44, 3, p. 294-301 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 11540165