Robert Dagil
Assistant Professor
- 2023
- Published
Bispecific T cell-engager targeting oncofetal chondroitin sulfate induces complete tumor regression and protective immune memory in mice
Skeltved, Nanna, Nordmaj, Mie Anemone, Pagh-Berendtsen, Nicolai, Dagil, Robert, Stormer, E. M. R., Al-Nakouzi, N., Jiang, K., Aicher, A., Heeschen, C., Gustavsson, Tobias, Choudhary, Swati, Gögenur, Ismail, Christensen, Jan Pravsgaard, Theander, Thor Grundtvig, Daugaard, M., Salanti, Ali & Nielsen, Morten Agertoug, 2023, In: Journal of Experimental & Clinical Cancer Research. 42, 16 p., 106.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
First-in-human use of a modular capsid virus-like vaccine platform: An open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2
Smit, M. J., Sander, A. F., Ariaans, M. B. P. A., Fougeroux, C., Heinzel, C., Fendel, R., Esen, M., Kremsner, P. G., Ter Heine, R., Wertheim, H. F., Idorn, M., Paludan, S. R., Underwood, A. P., Binderup, A., Ramirez, S., Bukh, J., Soegaard, M., Erdogan, S. M., Gustavsson, T., Clemmensen, S. & 14 others, , 2023, In: The Lancet Microbe. 4, 3, p. e140-e148Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intrinsically Disordered Proteins as an Instrument for Research-Integrating Teaching
Skriver, K., Sjørup, S. A., Langkilde, A. E., Balouka, E., Christensen, C. S., Carbel, K., Decker, J. N. V., Essenbæk, D. N., Gräf, J. F., Jessen, C. H., Kristensen, P., Merrild, C., Mortensen, T. S., Nalepa, I. F., Nordsteen, B. W., Svoren, S. K., van Hall, M., Weicher, J., Wind, M. L., Zhang, D. & 8 others, , 2023, In: The Biophysicist. 4 , 2, p. 1-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Malaria biomimetic for tumor targeted drug delivery
Pihl, J., Clausen, T. M., Zhou, J., Krishnan, N., Ørum-Madsen, M. S., Gustavsson, Tobias, Dagil, Robert, Daugaard, M., Choudhary, Swati, Foged, Camilla, Esko, J. D., Zhang, L., Fang, R. H. & Salanti, Ali, 2023, In: ACS Nano. 17, 14, p. 13500–13509Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA
Raghavan, Sai Sundar Rajan, Dagil, Robert, Lopez-Perez, Mary, Conrad, J., Bassi, Maria Rosaria, Quintana Varon, Maria del Pilar, Choudhary, Swati, Gustavsson, Tobias, Wang, Y., Gourdon, Pontus Emanuel, Ofori, M. F., Christensen, S. B., Minja, D. T. R., Schmiegelow, Christentze, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Hviid, Lars, Salanti, Ali, Lavstsen, Thomas & Wang, Kaituo, 2022, In: PLoS Pathogens. 18, 11, e1010924.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Internalization and trafficking of CSPG-bound recombinant VAR2CSA lectins in cancer cells
Wang, Chris Kedong, Nelepcu, I., Hui, D., Oo, H. Z., Truong, S., Zhao, S., Tahiry, Z., Esfandnia, S., Ghaidi, F., Adomat, H., Dagil, Robert, Gustavsson, Tobias, Choudhary, Swati, Salanti, Ali, Sorensen, P. H., Al Nakouzi, N. & Daugaard, M., 2022, In: Scientific Reports. 12, 3075.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reformation of the chondroitin sulfate glycocalyx enables progression of AR-independent prostate cancer
Al Nakouzi, N., Wang, C. K., Oo, H. Z., Nelepcu, I., Lallous, N., Spliid, C. B., Khazamipour, N., Lo, J., Truong, S., Collins, C., Hui, D., Esfandnia, S., Adomat, H., Clausen, T. M., Gustavsson, T., Choudhary, S., Dagil, R., Corey, E., Wang, Y., Chauchereau, A. & 6 others, , 2022, In: Nature Communications. 13, 4760.Research output: Contribution to journal › Journal article › Research › peer-review
The TH1 cell lineage-determining transcription factor T-bet suppresses TH2 gene expression by redistributing GATA3 away from TH2 genes
Hertweck, A., Vila de Mucha, M., Barber, P. R., Dagil, Robert, Porter, H., Ramos, A., Lord, G. M. & Jenner, R. G., 2022, In: Nucleic Acids Research. 50, 8, p. 4557–4573Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Two-component nanoparticle vaccine displaying glycosylated spike S1 domain induces neutralizing antibody response against SARS-CoV-2 variants
van Oosten, L., Altenburg, J. J., Fougeroux, C., Geertsema, C., van den End, F., Evers, W. A. C., Westphal, A. H., Lindhoud, S., van den Berg, W., Swarts, D. C., Deurhof, L., Suhrbier, A., Le, T. T., Torres Morales, S., Myeni, S. K., Kikkert, M., Sander, A. F., de Jongh, W. A., Dagil, R., Nielsen, M. A. & 9 others, , 26 Oct 2021, In: mBio. 12, 5, e0181321.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity
Fougeroux, C., Goksøyr, L., Idorn, M., Soroka, V., Myeni, S. K., Dagil, R., Janitzek, C. M., Søgaard, M., Aves, K-L., Horsted, E. W., Erdogan, S. M., Gustavsson, T., Dorosz, J., Clemmensen, S., Fredsgaard, L., Thrane, S., Vidal-Calvo, E. E., Khalifé, P., Hulen, T. M., Choudhary, S. & 27 others, , 2021, In: Nature Communications. 12, 1, p. 324Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding
Wang, Kaituo, Dagil, Robert, Lavstsen, Thomas, Misra, S. K., Spliid, C. B., Wang, Y., Gustavsson, Tobias, Sandoval, D. R., Vidal-Calvo, E. E., Choudhary, Swati, Agerbæk, Mette Ørskov, Lindorff-Larsen, Kresten, Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sharp, J. S., Clausen, Thomas Mandel, Gourdon, Pontus Emanuel & Salanti, Ali, 2021, In: Nature Communications. 12, 1, 10 p., 2956.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a bispecific immune engager using a recombinant malaria protein
Nordmaj, Mie Anemone, Roberts, M. E., Sachse, E. S., Dagil, Robert, Andersen, Anne Poder, Skeltved, Nanna, Grunddal, Kaare Villum, Erdogan, Sayit Mahmut, Choudhary, Swati, Gustavsson, Tobias, Ørum-madsen, M. S., Moskalev, I., Tian, W., Yang, Zhang, Clausen, Thomas Mandel, Theander, Thor Grundtvig, Daugaard, M., Nielsen, Morten Agertoug & Salanti, Ali, 2021, In: Cell Death & Disease. 12, 4, 11 p., 353.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oncofetal chondroitin sulfate is a highly expressed therapeutic target in non-small cell lung cancer
Oo, H. Z., Lohinai, Z., Khazamipour, N., Lo, J., Kumar, G., Pihl, J., Adomat, H., Nabavi, N., Behmanesh, H., Zhai, B., Dagil, R., Choudhary, S., Gustavsson, T., Clausen, T. M., Esko, J. D., Allen, J. W., Thompson, M. A., Tran, N. L., Moldvay, J., Dome, B. & 4 others, , 2021, In: Cancers. 13, 17, 16 p., 4489.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Capture and Detection of Circulating Glioma Cells Using the Recombinant VAR2CSA Malaria Protein
Bang-Christensen, S. R., Pedersen, R. S., Pereira, M. A., Clausen, T. M., Løppke, C., Sand, N. T., Ahrens, T. D., Jørgensen, A. M., Lim, Y. C., Goksøyr, L., Choudhary, S., Gustavsson, T., Dagil, R., Daugaard, M., Sander, A. F., Torp, M. H., Søgaard, M., Theander, T. G., Østrup, O., Lassen, U. & 3 others, , 2019, In: Cells. 8, 9, 21 p., 998.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties
Dagil, Robert, Ball, N. J., Ogrodowicz, R. W., Hobor, F., Purkiss, A. G., Kelly, G., Martin, S. R., Taylor, I. A. & Ramos, A., 2019, In: Nucleic Acids Research. 47, 8, p. 4334-4348 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein
Salanti, A., Clausen, T. M., Agerbæk, M. Ø., Al Nakouzi, N., Dahlbäck, M., Oo, H. Z., Lee, S., Gustavsson, T., Rich, J. R., Hedberg, B. J., Mao, Y., Barington, L., Pereira, M. A., LoBello, J., Endo, M., Fazli, L., Soden, J., Wang, C. K., Sander, A. F., Dagil, R. & 15 others, , 2015, In: Cancer Cell. 28, 4, p. 500-14 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Gentamicin binds to the megalin receptor as a competitive inhibitor using the common ligand binding motif of complement type repeats: insight from the nmr structure of the 10th complement type repeat domain alone and in complex with gentamicin
Dagil, Robert, O'Shea, Charlotte, Nykjær, A., Bonvin, A. M. J. J. & Kragelund, Birthe Brandt, 2013, In: The Journal of Biological Chemistry. 288, 6, p. 4424-35 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New horizons for lipoprotein receptors: communication by β-propellers
Andersen, O. M., Dagil, Robert & Kragelund, Birthe Brandt, 2013, In: Journal of Lipid Research. 54, p. 2763-2774 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
The WSXWS motif in cytokine receptors is a molecular switch involved in receptor activation: insight from structures of the prolactin receptor
Dagil, Robert, Knudsen, M. J., Olsen, Johan Gotthardt, O'Shea, Charlotte, Franzmann, M., Goffin, V., Teilum, Kaare, Breinholt, J. & Kragelund, Birthe Brandt, 2012, In: Structure. 20, 2, p. 270-282 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Streptococcal pyogenic exotoxin B (SpeB) boosts the contact system via binding of a-1 antitrypsin
Meinert Niclasen, L., Olsen, Johan Gotthardt, Dagil, Robert, Qing, Z., Sørensen, O. E. & Kragelund, Birthe Brandt, 2011, In: Biochemical Journal. 434, 1, p. 123-32 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Structure of the Mature Streptococcal Cysteine Protease Exotoxin mSpeB in Its Active Dimeric Form
Olsen, Johan Gotthardt, Dagil, Robert, Niclasen, L. M., Sørensen, O. E. & Kragelund, Birthe Brandt, 2009, In: Journal of Molecular Biology. 393, 3, p. 693-703 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
On the use of pseudocontact shifts in the structure determination of metalloproteins
Jensen, M. R., Hansen, D. F., Ayna, U., Dagil, Robert, Hass, S. A. M., Christensen, H. E. M. & Led, J. J., 2006, In: Magnetic Resonance in Chemistry. 44, 3, p. 294-301 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11540165
Most downloads
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206
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Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
121
downloads
IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
114
downloads
Capture and Detection of Circulating Glioma Cells Using the Recombinant VAR2CSA Malaria Protein
Research output: Contribution to journal › Journal article › Research › peer-review
Published