Michael Alifrangis

Michael Alifrangis

Associate Professor

Member of:

  • DRUGS team


  1. 1999
  2. Published

    IgG reactivities against recombinant Rhoptry-Associated Protein-1 (rRAP-1) are associated with mixed Plasmodium infections and protection against disease in Tanzanian children

    Alifrangis, Michael, Lemnge, M. M., Moon, R., Theisen, Michael, Bygbjerg, Ib Christian, Ridley, R. G. & Jakobsen, P. H., 1999, In: Parasitology. 119 ( Pt 4), p. 337-42 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2002
  4. Published

    Plasmodium falciparum variant surface antigen expression varies between isolates causing severe and nonsevere malaria and is modified by acquired immunity

    Nielsen, Morten Agertoug, Staalsoe, T., Kurtzhals, Jørgen, Goka, B. Q., Dodoo, D., Alifrangis, Michael, Theander, Thor Grundtvig, Akanmori, B. D. & Hviid, Lars, 2002, In: Journal of Immunology. 168, 7, p. 3444-50 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Diversity of Plasmodium falciparum clones infecting children living in a holoendemic area in north-eastern Tanzania

    Magesa, S. M., Mdira, K. Y., Babiker, H. A., Alifrangis, Michael, Färnert, A., Simonsen, P. E., Bygbjerg, Ib Christian, Walliker, D. & Jakobsen, P. H., 2002, In: Acta Tropica. 84, 2, p. 83-92 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Molecular surveillance of drug resistance through imported isolates of Plasmodium falciparum in Europe

    Jelinek, T., Peyerl-Hoffmann, G., Mühlberger, N., Wichmann, O., Wilhelm, M., Schmider, N., Grobusch, M. P., von Sonnenburg, F., Gascon, J., Laferl, H., Hatz, C., Alifrangis, M., Burchard, G., McWhinney, P., Schulze, M., Kollaritsch, H., da Cunha, S., Beran, J., Kern, P., Gjørup, I. & 1 others, Cuadros, J., 2002, In: Malaria Journal. 1, p. 11

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Pyrimethamine/sulfadoxine combination in the treatment of uncomplicated falciparum malaria: relation between dihydropteroate synthase/dihydrofolate reductase genotypes, sulfadoxine plasma levels, and treatment outcome

    Khalil, I., Alifrangis, Michael, Rønn, A. M., Gabar, H. A., Jelinek, T., Satti, G. M. H. & Bygbjerg, Ib Christian, 2002, In: American Journal of Tropical Medicine and Hygiene. 67, 3, p. 225-9 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2003
  9. Published

    Atovaquone/proguanil resistance in Africa: a case report

    David, K. P., Alifrangis, Michael, Salanti, Ali, Vestergaard, L. S., Rønn, A. & Bygbjerg, Ib Christian, 2003, In: Scandinavian Journal of Infectious Diseases. 35, 11-12, p. 897-8 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Different mutation patterns of atovaquone resistance to Plasmodium falciparum in vitro and in vivo: rapid detection of codon 268 polymorphisms in the cytochrome b as potential in vivo resistance marker

    Schwöbel, B., Alifrangis, Michael, Salanti, Ali & Jelinek, T., 2003, In: Malaria Journal. 2, p. 5

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Dihydrofolate reductase and dihydropteroate synthase genotypes associated with in vitro resistance of Plasmodium falciparum to pyrimethamine, trimethoprim, sulfadoxine, and sulfamethoxazole

    Khalil, I., Rønn, A. M., Alifrangis, Michael, Gabar, H. A., Satti, G. M. H. & Bygbjerg, Ib Christian, 2003, In: American Journal of Tropical Medicine and Hygiene. 68, 5, p. 586-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Increasing prevalence of wildtypes in the dihydrofolate reductase gene of Plasmodium falciparum in an area with high levels of sulfadoxine/pyrimethamine resistance after introduction of treated bed nets

    Alifrangis, Michael, Lemnge, M. M., Rønn, A. M., Segeja, M. D., Magesa, S. M., Khalil, I. F. & Bygbjerg, Ib Christian, 2003, In: American Journal of Tropical Medicine and Hygiene. 69, 3, p. 238-43 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Molecular surveillance of the antifolate-resistant mutation I164L in imported African isolates of Plasmodium falciparum in Europe: sentinel data from TropNetEurop

    Wichmann, O., Jelinek, T., Peyerl-Hoffmann, G., Mühlberger, N., Grobusch, M. P., Gascon, J., Matteelli, A., Hatz, C., Laferl, H., Schulze, M., Burchard, G., da Cunha, S., Beran, J., McWhinney, P., Kollaritsch, H., Kern, P., Cuadros, J., Alifrangis, Michael, Gjørup, I. & European Network on Surveillance of Imported Infectious Diseases (TropNetEurop), E. N. O. S. O. I. I. D. (., 2003, In: Malaria Journal. 2, p. 17

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Prediction of Plasmodium falciparum resistance to sulfadoxine/pyrimethamine in vivo by mutations in the dihydrofolate reductase and dihydropteroate synthetase genes: a comparative study between sites of differing endemicity

    Alifrangis, Michael, Enosse, S., Khalil, I. F., Tarimo, D. S., Lemnge, M. M., Thompson, R., Bygbjerg, Ib Christian & Rønn, A. M., 2003, In: American Journal of Tropical Medicine and Hygiene. 69, 6, p. 601-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Prediction of Plasmodium falciparum resistance to sulfadoxine/ pyrimethamine in vivo by mutations in the dihydrofolate reductase and dihydropteroate synthetase genes: A comparative study between sites of differing endemicity

    Alifrangis, Michael, Enosse, S., Khalil, I. F., Tarimo, D. S., Lemnge, M. M., Thompson, R., Bygbjerg, Ib Christian & Rønn, A. M., 1 Dec 2003, In: American Journal of Tropical Medicine and Hygiene. 69, 6, p. 601-606 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2004
  17. Published

    Homology building as a means to define antigenic epitopes on dihydrofolate reductase (DHFR) from Plasmodium falciparum

    Alifrangis, Michael, Christensen, I. T., Jørgensen, Flemming Steen, Rønn, A. M., Weng, J. E., Chen, M., Bygbjerg, Ib Christian, Sirawaraporn, W., Palarasah, Y. & Koch, C., 2004, In: Malaria Journal. 3, p. 16

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Screening for mutations related to atovaquone/proguanil resistance in treatment failures and other imported isolates of Plasmodium falciparum in Europe

    Wichmann, O., Muehlberger, N., Jelinek, T., Alifrangis, M., Peyerl-Hoffmann, G., Muhlen, M., Grobusch, M. P., Gascon, J., Matteelli, A., Laferl, H., Bisoffi, Z., Ehrhardt, S., Cuadros, J., Hatz, C., Gjorup, I., McWhinney, P., Beran, J., da Cunha, S., Schulze, M., Kollaritsch, H. & 4 others, Kern, P., Fry, G., Richter, J. & European Network on Surveillance of Imported Infectious Diseases, E. N. O. S. O. I. I. D., 2004, In: Journal of Infectious Diseases. 190, 9, p. 1541-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2005
  20. Published

    A simple, high-throughput method to detect Plasmodium falciparum single nucleotide polymorphisms in the dihydrofolate reductase, dihydropteroate synthase, and P. falciparum chloroquine resistance transporter genes using polymerase chain reaction- and enzyme-linked immunosorbent assay-based technology

    Alifrangis, Michael, Enosse, S., Pearce, R., Drakeley, C., Roper, C., Khalil, I. F., Nkya, W. M., Rønn, A. M., Theander, Thor Grundtvig & Bygbjerg, Ib Christian, 2005, In: American Journal of Tropical Medicine and Hygiene. 72, 2, p. 155-62 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Cytophilic antibodies to Plasmodium falciparum glutamate rich protein are associated with malaria protection in an area of holoendemic transmission

    Lusingu, J. P. A., Vestergaard, L. S., Alifrangis, Michael, Mmbando, B. P., Theisen, M., Kitua, A. Y., Lemnge, M. M. & Theander, Thor Grundtvig, 2005, In: Malaria Journal. 4, p. 48

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Falciparum malaria in the north of Laos: the occurrence and implications of the Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene haplotype SVMNT

    Dittrich, S., Alifrangis, Michael, Stohrer, J. M., Thongpaseuth, V., Vanisaveth, V., Phetsouvanh, R., Phompida, S., Khalil, I. F. & Jelinek, T., 2005, In: Tropical Medicine & International Health. 10, 12, p. 1267-70 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Optimizing malarial epidemiological studies in areas of low transmission.

    Amerasinghe, P. H., Alifrangis, Michael, van der Hoek, W., Wirtz, R. A., Amerasinghe, F. P. & Konradsen, Flemming, 2005, In: Southeast Asian Journal of Tropical Medicine and Public Health. 36, 5, p. 1079-84 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Rapid screening for glucose-6-phosphate dehydrogenase deficiency and haemoglobin polymorphisms in Africa by a simple high-throughput SSOP-ELISA method

    Enevold, A., Vestergaard, L. S., Lusingu, J., Drakeley, C. J., Lemnge, M. M., Theander, Thor Grundtvig, Bygbjerg, Ib Christian & Alifrangis, Michael, 2005, In: Malaria Journal. 4, p. 61

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Response of Plasmodium falciparum to cotrimoxazole therapy: relationship with plasma drug concentrations and dihydrofolate reductase and dihydropteroate synthase genotypes

    Khalil, I. F., Rønn, A. M., Alifrangis, Michael, Gabar, H. A., Jelinek, T., Satti, G. M. H. & Bygbjerg, Ib Christian, 2005, In: American Journal of Tropical Medicine and Hygiene. 73, 1, p. 174-7 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    The roles of the pfcrt 76T and pfmdr1 86Y mutations, immunity and the initial level of parasitaemia, in predicting the outcome of chloroquine treatment in two areas with different transmission intensities

    Khalil, I. F., Alifrangis, Michael, Tarimo, D. S., Staalsø, T., Satti, G. M. H., Theander, Thor Grundtvig, Rønn, A. M. & Bygbjerg, Ib Christian, 2005, In: Annals of Tropical Medicine and Parasitology. 99, 5, p. 441-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2006
  28. Published

    A fixed-dose 24-hour regimen of artesunate plus sulfamethoxypyrazine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in eastern Sudan

    Adam, I., Magzoub, M., Osman, M. E., Khalil, I. F., Alifrangis, Michael & Elmardi, K. A., 2006, In: Annals of Clinical Microbiology and Antimicrobials. 5, p. 18

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    High reinfection rate and treatment failures in children treated with amodiaquine for falciparum malaria in Muheza villages, Northeastern Tanzania

    Lemnge, M., Alifrangis, Michael, Kafuye, M. Y., Segeja, M. D., Gesase, S., Minja, D., Massaga, J. J., Rønn, A. M. & Bygbjerg, Ib Christian, 2006, In: American Journal of Tropical Medicine and Hygiene. 75, 2, p. 188-93 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Occurrence of the Southeast Asian/South American SVMNT haplotype of the chloroquine-resistance transporter gene in Plasmodium falciparum in Tanzania

    Alifrangis, Michael, Dalgaard, M. B., Lusingu, J. P., Vestergaard, L. S., Staalsoe, T., Jensen, Anja Ramstedt, Enevold, A., Rønn, A. M., Khalil, I. F., Warhurst, D. C., Lemnge, M. M., Theander, Thor Grundtvig & Bygbjerg, Ib Christian, 2006, In: Journal of Infectious Diseases. 193, 12, p. 1738-41 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Occurrence of the leucine-to-phenylalanine knockdown resistance (kdr) mutation in Anopheles arabiensis populations in Tanzania, detected by a simplified high-throughput SSOP-ELISA method

    Kulkarni, M. A., Rowland, M., Alifrangis, Michael, Mosha, F. W., Matowo, J., Malima, R., Peter, J., Kweka, E., Lyimo, I., Magesa, S., Salanti, Ali, Rau, M. E. & Drakeley, C., 2006, In: Malaria Journal. 5, p. Art no. 56-

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 11975