Michael Alifrangis

Michael Alifrangis

Associate Professor

Member of:

  • DRUGS team


  1. Published

    The roles of the pfcrt 76T and pfmdr1 86Y mutations, immunity and the initial level of parasitaemia, in predicting the outcome of chloroquine treatment in two areas with different transmission intensities

    Khalil, I. F., Alifrangis, Michael, Tarimo, D. S., Staalsø, T., Satti, G. M. H., Theander, Thor Grundtvig, Rønn, A. M. & Bygbjerg, Ib Christian, 2005, In: Annals of Tropical Medicine and Parasitology. 99, 5, p. 441-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Dihydrofolate reductase and dihydropteroate synthase genotypes associated with in vitro resistance of Plasmodium falciparum to pyrimethamine, trimethoprim, sulfadoxine, and sulfamethoxazole

    Khalil, I., Rønn, A. M., Alifrangis, Michael, Gabar, H. A., Satti, G. M. H. & Bygbjerg, Ib Christian, 2003, In: American Journal of Tropical Medicine and Hygiene. 68, 5, p. 586-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Pyrimethamine/sulfadoxine combination in the treatment of uncomplicated falciparum malaria: relation between dihydropteroate synthase/dihydrofolate reductase genotypes, sulfadoxine plasma levels, and treatment outcome

    Khalil, I., Alifrangis, Michael, Rønn, A. M., Gabar, H. A., Jelinek, T., Satti, G. M. H. & Bygbjerg, Ib Christian, 2002, In: American Journal of Tropical Medicine and Hygiene. 67, 3, p. 225-9 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Development of ELISA-based methods to measure the anti-malarial drug chloroquine in plasma and in pharmaceutical formulations

    Khalil, I. F., Alifrangis, Michael, Recke, C., Hoegberg, L. C., Ronn, A., Bygbjerg, Ib Christian & Koch, C., 1 Jan 2011, In: Malaria Journal. 10, p. 249

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Measurement of lumefantrine and its metabolite in plasma by high performance liquid chromatography with ultraviolet detection

    Khalil, I. F., Abildrup, U., Alifrangis, L. H., Maiga, D., Alifrangis, Michael, Hoegberg, L., Vestergaard, L. S., Persson, O. P., Nyagonde, N., Lemnge, M. M., Theander, Thor Grundtvig & Bygbjerg, Ib Christian, 5 Jan 2011, In: Journal of Pharmaceutical and Biomedical Analysis. 54, 1, p. 168-72 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Response of Plasmodium falciparum to cotrimoxazole therapy: relationship with plasma drug concentrations and dihydrofolate reductase and dihydropteroate synthase genotypes

    Khalil, I. F., Rønn, A. M., Alifrangis, Michael, Gabar, H. A., Jelinek, T., Satti, G. M. H. & Bygbjerg, Ib Christian, 2005, In: American Journal of Tropical Medicine and Hygiene. 73, 1, p. 174-7 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Occurrence of the leucine-to-phenylalanine knockdown resistance (kdr) mutation in Anopheles arabiensis populations in Tanzania, detected by a simplified high-throughput SSOP-ELISA method

    Kulkarni, M. A., Rowland, M., Alifrangis, Michael, Mosha, F. W., Matowo, J., Malima, R., Peter, J., Kweka, E., Lyimo, I., Magesa, S., Salanti, Ali, Rau, M. E. & Drakeley, C., 2006, In: Malaria Journal. 5, p. Art no. 56-

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Patterns of infections, aetiological agents, and antimicrobial resistance at a tertiary care hospital in northern Tanzania

    Kumburu, H. H., Sonda, T., Mmbaga, B. T., Alifrangis, Michael, Lund, O., Kibiki, G. & Aarestrup, F. M., Oct 2017, In: Tropical Medicine & International Health. 22, S1, p. 360-360

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  9. Published

    Hospital epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) in a tertiary care hospital in Moshi Tanzania as determined by whole genome sequencing

    Kumburu, H. H., Sonda, T., Leetcharoenphon, P., van Zwetselaar, M., Lukjancenko, O., Alifrangis, Michael, Lund, O., Mmbaga, B. T., Kibiki, G. & Aarestrup, F. M., Oct 2017, In: Tropical Medicine & International Health. 22, S1, p. 359-359

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  10. Published

    Using WGS to identify antibiotic resistance genes and predict antimicrobial resistance phenotypes in MDR Acinetobacter baumannii in Tanzania

    Kumburu, H. H., Sonda, T., van Zwetselaar, M., Leekitcharoenphon, P., Lukjancenko, O., Mmbaga, B. T., Alifrangis, Michael, Lund, O., Aarestrup, F. M. & Kibiki, G. S., 1 Jun 2019, In: The Journal of antimicrobial chemotherapy. 74, 6, p. 1484-1493 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Hospital epidemiology of methicillin-resistant Staphylococcus aureus in a tertiary care hospital in Moshi, Tanzania, as determined by whole genome sequencing

    Kumburu, H. H., Sonda, T., Leekitcharoenphon, P., van Zwetselaar, M., Lukjancenko, O., Alifrangis, Michael, Lund, O., Mmbaga, B. T., Kibiki, G. & Aarestrup, F. M., 2018, In: Journal of Biomedicine and Biotechnology. 2018, 12 p., 2087693.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Patterns of infections, aetiological agents and antimicrobial resistance at a tertiary care hospital in northern Tanzania

    Kumburu, H. H., Sonda, T., Mmbaga, B. T., Alifrangis, Michael, Lund, O., Kibiki, G. & Aarestrup, F. M., Apr 2017, In: Tropical Medicine & International Health. 22, 4, p. 454-464 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Association between α-thalassaemia trait, Plasmodium falciparum asexual parasites and gametocyte carriage in a malaria endemic area in Southern Ghana

    Lamptey, H., Ofori, M. F., Adu, B., Kusi, K. A., Dickson, E. K., Quakyi, I. & Alifrangis, Michael, 2019, In: BMC Research Notes. 12, 5 p., 134.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    ASSOCIATION BETWEEN THE ALPHA THALASSEMIA TRAIT AND PLASMODIUM FALCIPARUM GAMETOCYTEMIA IN A MALARIA ENDEMIC AREA IN GHANA

    Lamptey, H., Ofori, M. F., Owusu-Yeboa, E., Kusi, K. A., Adu, B., Arku, A. T., Alifrangis, Michael & Quakyi, I., Nov 2017, In: American Journal of Tropical Medicine and Hygiene. 95, 5 Suppl., p. 297-297

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  15. Published

    The prevalence of submicroscopic Plasmodium falciparum gametocyte carriage and multiplicity of infection in children, pregnant women and adults in a low malaria transmission area in Southern Ghana 11 Medical and Health Sciences 1108 Medical Microbiology 11 Medical and Health Sciences 1117 Public Health and Health Services

    Lamptey, H., Ofori, M. F., Kusi, K. A., Adu, B., Owusu-Yeboa, E., Kyei-Baafour, E., Arku, A. T., Bosomprah, S., Alifrangis, Michael & Quakyi, I. A., 2018, In: Malaria Journal. 17, 12 p., 331.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    High reinfection rate and treatment failures in children treated with amodiaquine for falciparum malaria in Muheza villages, Northeastern Tanzania

    Lemnge, M., Alifrangis, Michael, Kafuye, M. Y., Segeja, M. D., Gesase, S., Minja, D., Massaga, J. J., Rønn, A. M. & Bygbjerg, Ib Christian, 2006, In: American Journal of Tropical Medicine and Hygiene. 75, 2, p. 188-93 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Cytophilic antibodies to Plasmodium falciparum glutamate rich protein are associated with malaria protection in an area of holoendemic transmission

    Lusingu, J. P. A., Vestergaard, L. S., Alifrangis, Michael, Mmbando, B. P., Theisen, M., Kitua, A. Y., Lemnge, M. M. & Theander, Thor Grundtvig, 2005, In: Malaria Journal. 4, p. 48

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Effect of monthly intermittent preventive treatment with dihydroartemisinin-piperaquine with and without azithromycin versus monthly sulfadoxine-pyrimethamine on adverse pregnancy outcomes in Africa: a double-blind randomised, partly placebo-controlled trial

    Madanitsa, M., Barsosio, H. C., Minja, D. T. R., Mtove, G., Kavishe, R. A., Dodd, J., Saidi, Q., Onyango, E. D., Otieno, K., Wang, D., Ashorn, U., Hill, J., Mukerebe, C., Gesase, S., Msemo, O. A., Mwapasa, V., Phiri, K. S., Maleta, K., Klein, N., Magnussen, P. & 9 others, Lusingu, J. P. A., Kariuki, S., Mosha, J. F., Alifrangis, Michael, Hansson, Helle Smedegaard, Schmiegelow, Christentze, Gutman, J. R., Chico, R. M. & Ter Kuile, F. O., 2023, In: The Lancet. 401, 10381, p. 1020-1036 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Diversity of Plasmodium falciparum clones infecting children living in a holoendemic area in north-eastern Tanzania

    Magesa, S. M., Mdira, K. Y., Babiker, H. A., Alifrangis, Michael, Färnert, A., Simonsen, P. E., Bygbjerg, Ib Christian, Walliker, D. & Jakobsen, P. H., 2002, In: Acta Tropica. 84, 2, p. 83-92 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Attributable risk factors for asymptomatic malaria and anaemia and their association with cognitive and psychomotor functions in schoolchildren of north-eastern Tanzania

    Makenga, G., Baraka, V., Francis, F., Minja, D. T. R., Gesase, S., Kyaruzi, E., Mtove, G., Nakato, S., Madebe, R., Søeborg, S. R., Langhoff, K. H., Hansson, Helle Smedegaard, Alifrangis, Michael, Lusingu, J. P. A. & Van Geertruyden, J., 2022, In: PLoS ONE. 17, 5, e0268654.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Prevalence of Plasmodium falciparum resistance markers to sulfadoxine-pyrimethamine among pregnant women receiving intermittent preventive treatment for malaria in Uganda

    Mbonye, A. K., Birungi, J., Yanow, S. K., Shokoples, S., Malamba, S., Alifrangis, Michael & Magnussen, Pascal, Sep 2015, In: Antimicrobial Agents and Chemotherapy. 59, 9, p. 5475-82 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Discordant patterns of genetic variation at two chloroquine resistance loci in worldwide populations of the malaria parasite Plasmodium falciparum

    Mehlotra, R. K., Mattera, G., Bockarie, M. J., Maguire, J. D., Baird, J. K., Sharma, Y. D., Alifrangis, Michael, Dorsey, G., Rosenthal, P. J., Fryauff, D. J., Kazura, J. W., Stoneking, M. & Zimmerman, P. A., 2008, In: Antimicrobial Agents and Chemotherapy. 52, 6, p. 2212-22 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Identification of the PfK13 mutations R561H and P441L in the Democratic Republic of Congo

    Mesia Kahunu, G., Wellmann Thomsen, S., Wellmann Thomsen, L., Muhindo Mavoko, H., Mitashi Mulopo, P., Hocke, Emma Filtenborg, Mandoko Nkoli, P., Baraka, V., Minja, D. T. R., Mousa, A., Roper, C., Mbongi Moke, D., Mumba Ngoyi, D., Mukomena Sompwe, E., Muyembe Tanfum, J. J., Hansson, Helle Smedegaard & Alifrangis, Michael, 2024, In: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 139, p. 41-49 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Association between mannose-binding lectin polymorphisms and Wuchereria bancrofti infection in two communities in north-eastern Tanzania

    Meyrowitsch, Dan Wolf, Simonsen, P. E., Garred, Peter, Dalgaard, M., Magesa, S. M. & Alifrangis, Michael, 2010, In: American Journal of Tropical Medicine and Hygiene. 82, 1, p. 115-20 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Association between a human genetic marker (MBL) and the long-term status of Wuchereria bancrofti infection in endemic communities in Tanga Region, Tanzania

    Meyrowitsch, Dan Wolf, Alifrangis, Michael, Dalgaard, M. B., Garred, Peter, Magesa, S. M. & Simonsen, P. E., 2008, Lymphatic filariasis research and control in Eastern and Southern Africa. Simonsen, P. E., Malecela, M. N., Michael, E. & Mackenzie, C. D. (eds.). p. 179 1 p.

    Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

ID: 11975