Lars Hviid

Lars Hviid

Professor

Member of:

  • SURFACE team


  1. 2013
  2. Published

    A Novel Domain Cassette Identifies Plasmodium falciparum PfEMP1 Proteins Binding ICAM-1 and Is a Target of Cross-Reactive, Adhesion-Inhibitory Antibodies

    Bengtsson, A., Joergensen, L., Rask, T. S., Olsen, R. W., Andersen, M. A., Turner, Louise, Theander, Thor Grundtvig, Hviid, Lars, Higgins, M. K., Craig, A., Brown, A. & Jensen, Anja Ramstedt, 2013, In: Journal of Immunology. 190, 1, p. 240-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Plasmodium falciparum Expressing Domain Cassette 5 Type PfEMP1 (DC5-PfEMP1) Bind PECAM1

    Berger, S. S., Turner, Louise, Wang, Christian William, Petersen, J. E. V., Kraft, M., Lusingu, J. P. A., Mmbando, B., Marquard, A. M., Bengtsson, D. B. A. C., Hviid, Lars, Nielsen, Morten Agertoug, Theander, Thor Grundtvig & Lavstsen, Thomas, 2013, In: PloS one. 8, 7, p. e69117

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Transfected HEK293 Cells Expressing Functional Recombinant Intercellular Adhesion Molecule 1 (ICAM-1) - A Receptor Associated with Severe Plasmodium falciparum Malaria

    Bengtsson, A., Joergensen, L., Barbati, Z. R., Craig, A., Hviid, Lars & Jensen, Anja Ramstedt, 2013, In: PLOS ONE. 8, 7, p. e69999

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Malaria

    Riley, E. M., Hviid, Lars & Theander, Thor Grundtvig, 22 Oct 2013, Parasitic Infections and the Immune System. Elsevier Science Inc., p. 119-143 25 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  6. Published

    Cytokine response to pregnancy-associated recrudescence of Plasmodium berghei infection in mice with pre-existing immunity to malaria

    Megnekou, R., Staalsø, Trine & Hviid, Lars, 1 Nov 2013, In: Malaria Journal. 12, 1, p. 387

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2014
  8. Published

    Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites

    Sleebs, B. E., Lopaticki, S., Marapana, D. S., O'Neill, M. T., Rajasekaran, P., Gazdik, M., Günther, S., Whitehead, L. W., Lowes, K. N., Barfod, Lea Klingenberg, Hviid, Lars, Shaw, P. J., Hodder, A. N., Smith, B. J., Cowman, A. F. & Boddey, J. A., 2014, In: P L o S Biology. 12, 7, p. e1001897

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Modeling malaria infection and immunity against variant surface antigens in Príncipe island, West Africa

    Bandeiras, C., Trovoada, M. J., Gonçalves, L. A., Marinho, C. R. F., Turner, Louise, Hviid, Lars, Penha-Gonçalves, C. & Gomes, M. G. M., 2014, In: PloS one. 9, 2, p. e88110

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    B-cell responses to pregnancy-restricted and -unrestricted Plasmodium falciparum erythrocyte membrane protein 1 antigens in Ghanaian women naturally exposed to malaria parasites

    Ampomah, P., Stevenson, L., Ofori, M. F., Barfod, Lea Klingenberg & Hviid, Lars, May 2014, In: Infection and Immunity. 82, 5, p. 1860-71 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Kinetics of B Cell responses to Plasmodium falciparum erythrocyte membrane protein 1 in Ghanaian women naturally exposed to malaria parasites

    Ampomah, P., Stevenson, L., Ofori, M. F., Barfod, Lea Klingenberg & Hviid, Lars, 1 Jun 2014, In: Journal of Immunology. 192, 11, p. 5236-44 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2015
  13. Published

    Plasmodium falciparum-infected erythrocyte knob density is linked to the PfEMP1 variant expressed

    Subramani, R., Quadt, K., Jeppesen, A. E., Hempel, C., Petersen, J. E. V., Hassenkam, Tue, Hviid, Lars & Barfod, Lea Klingenberg, 2015, In: mBio. 6, 5, 7 p., e01456-15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Multiple Plasmodium falciparum erythrocyte membrane protein 1 variants per genome can bind IgM via its Fc fragment Fcμ

    Jeppesen, A., Ditlev, S. B., Soroka, V., Stevenson, E. K., Turner, Louise, Dzikowski, R., Hviid, Lars & Barfod, Lea Klingenberg, 2015, In: Infection and Immunity. 83, 10, p. 3972-81 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Trying to remember: immunological B cell memory to malaria

    Hviid, Lars, Barfod, Lea Klingenberg & Fowkes, F. J. I., Mar 2015, In: Trends in Parasitology. 31, 3, p. 89-94 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    PfEMP1 – a parasite protein family of key importance in Plasmodium falciparum malaria immunity and pathogenesis

    Hviid, Lars & Jensen, Anja Ramstedt, Apr 2015, Advances in Parasitology. Rollinson, D. & Stothard, J. R. (eds.). Vol. 88. p. 51-84 34 p. (Advances in Parasitology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  17. Published

    Investigating the function of Fc -specific binding of IgM to Plasmodium falciparum erythrocyte membrane protein 1 mediating erythrocyte rosetting

    Stevenson, L., Huda, P., Jeppesen, A., Laursen, E. T. F., Rowe, J. A., Craig, A., Streicher, W., Barfod, Lea Klingenberg & Hviid, Lars, Jun 2015, In: Cellular Microbiology. 17, 6, p. 819-31 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Rifins, rosetting, and red blood cells

    Wang, Christian William & Hviid, Lars, Jul 2015, In: Trends in Parasitology. 31, 7, p. 285-6 2 p.

    Research output: Contribution to journalJournal articleCommissionedpeer-review

  19. Published

    α2-macroglobulin can crosslink multiple Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) molecules and may facilitate adhesion of parasitized erythrocytes

    Stevenson, L., Laursen, E., Cowan, G. J., Bandoh, B., Barfod, Lea Klingenberg, Cavanagh, D. R., Andersen, G. R. & Hviid, Lars, Jul 2015, In: P L o S Pathogens. 11, 7, p. 1-19 19 p., e1005022.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2016
  21. Published

    Immunoglobulin M: restrainer of inflammation and mediator of immune evasion by Plasmodium falciparum malaria

    Pleass, R. J., Moore, S. C., Stevenson, L. & Hviid, Lars, Feb 2016, In: Trends in Parasitology. 32, 2, p. 108-119 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  22. Published

    Orm i toilettet

    Hviid, Lars, Møller-Bisgaard, S. & Kurtzhals, Jørgen, 15 Feb 2016, In: Ugeskrift for Laeger. 178, 7, 1 p., V67428.

    Research output: Contribution to journalJournal articleCommunication

  23. 2017
  24. Published

    Dansk malariaforskning fra spæd begyndelse til international styrkeposition

    Jepsen, M. P. G., Jepsen, S., Kurtzhals, Jørgen & Hviid, Lars, 2017, In: Ugeskrift for Laeger. 179, 20, p. 866-869 V10160756.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Malaria parasite evasion of classical complement pathway attack

    Larsen, M. D., Ditlev, S., Olmos, R. B., Ampomah, P., Ofori, M. F., Garred, Peter & Hviid, Lars, 2017, In: Molecular Immunology. 89, p. 159-159

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  26. Published

    Structure-guided identification of a family of dual receptor-binding PfEMP1 that is associated with cerebral malaria

    Lennartz, F., Adams, Y., Bengtsson, A., Olsen, R. W., Turner, L., Ndam, N. T., Ecklu-Mensah, G. D., Moussiliou, A., Ofori, M. F., Gamain, B., Lusingu, J. P., Petersen, J. E. V., Wang, C. W., Nunes-Silva, S., Jespersen, J. S., Lau, C. K. Y., Theander, T. G., Lavstsen, T., Hviid, L., Higgins, M. K. & 1 others, Jensen, Anja Ramstedt, 8 Mar 2017, In: Cell Host & Microbe. 21, 3, p. 403-414 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2018
  28. Published

    Blood outgrowth endothelial cells (BOECs) as a novel tool for studying adhesion of Plasmodium falciparum-infected erythrocytes

    Ecklu-Mensah, G., Olsen, Rebecca Wendelboe, Bengtsson, A., Ofori, M. F., Hviid, Lars, Jensen, Anja Ramstedt & Adams, Yvonne, 2018, In: PLoS ONE. 13, 10, 12 p., e0204177.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Etiology of placental Plasmodium falciparum malaria in African women

    Ofori, M. F., Lamptey, H., Dickson, E. K., Kyei-Baafour, E. & Hviid, Lars, 2018, In: The Journal of Infectious Diseases. 218, 2, p. 277-281 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    IgG responses to the Plasmodium falciparum antigen VAR2CSA in Colombia are restricted to pregnancy and are not induced by exposure to Plasmodium vivax

    Lopez-Perez, Mary, Larsen, M. D., Bayarri-Olmos, R., Ampomah, P., Stevenson, L., Arévalo-Herrera, M., Herrera, S. & Hviid, Lars, 2018, In: Infection and Immunity. 86, 8, e00136-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Kinetics of antibody responses to PfRH5-complex antigens in Ghanaian children with Plasmodium falciparum malaria

    Partey, Frederica Dedo, Castberg, F. C., Sarbah, E. W., Silk, S. E., Awandare, G. A., Draper, S. J., Opoku, N., Kweku, M., Ofori, M. F., Hviid, Lars & Barfod, Lea Klingenberg, 2018, In: PLOS ONE. 13, 6, 14 p., e0198371.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Natural and vaccine-induced acquisition of cross-reactive IgG inhibiting ICAM-1-specific binding of a Plasmodium falciparum PfEMP1 subtype associated specifically with cerebral malaria

    Olsen, Rebecca Wendelboe, Ecklu-Mensah, G., Bengtsson, A., Ofori, M. F., Lusingu, J. P. A., Castberg, F. C., Hviid, Lars, Adams, Yvonne & Jensen, Anja Ramstedt, 2018, In: Infection and Immunity. 86, 4, 17 p., e00622-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Increased Plasmodium chabaudi malaria mortality in mice with nutritional iron deficiency can be reduced by short-term adjunctive iron supplementation

    Castberg, F. C., Maretty, L., Staalsø, Trine, Hempel, C., Clasen-Linde, E., Hviid, Lars & Kurtzhals, Jørgen, 16 Jan 2018, In: Malaria Journal. 17, 1, 12 p., 34.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    A vaccine targeted specifically to prevent cerebral malaria - is there hope?

    Hviid, Lars, Lavstsen, Thomas & Jensen, Anja Ramstedt, Jul 2018, In: Expert Review of Vaccines. 17, 7, p. 565-567 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  35. Published

    Malaria causes long-term effects on markers of iron status in children: a critical assessment of existing clinical and epidemiological tools

    Castberg, F. C., Sarbah, E. W., Koram, K. A., Opoku, N., Ofori, M. F., Styrishave, Bjarne, Hviid, Lars & Kurtzhals, Jørgen, 11 Dec 2018, In: Malaria Journal. 17, 1, 464.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. 2019
  37. Published

    Acquisition of IgG to ICAM-1-Binding DBLβ Domains in the Plasmodium falciparum erythrocyte membrane protein 1 antigen family varies between Groups A, B, and C

    Olsen, Rebecca Wendelboe, Ecklu-Mensah, G., Bengtsson, A., Ofori, M. F., Kusi, K. A., Koram, K. A., Hviid, Lars, Adams, Yvonne & Jensen, Anja Ramstedt, 2019, In: Infection and Immunity. 87, 10, e00224-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Comprehensive analysis of Fc-mediated IgM binding to the Plasmodium falciparum erythrocyte membrane protein 1 family in three parasite clones

    Quintana Varon, Maria del Pilar, Ecklu-Mensah, G., Tcherniuk, S. O., Ditlev, S. B., Oleinikov, A. V., Hviid, Lars & Lopez-Perez, Mary, 2019, In: Scientific Reports. 9, 1, 11 p., 6050.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Evasion of classical complement pathway activation on Plasmodium falciparum-infected erythrocytes opsonized by PfEMP1-specific IgG

    Larsen, M. D., Quintana Varon, Maria del Pilar, Ditlev, S. B., Bayarri-Olmos, R., Ofori, M. F., Hviid, Lars & Garred, Peter, 2019, In: Frontiers in Immunology. 9, 3088.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Functional antibodies against placental malaria parasites are variant dependent and differ by geographic region

    Doritchamou, J., Teo, A., Morrison, R., Arora, G., Kwan, J., Manzella-Lapeira, J., Medina-Maldonado, S., Langhorne, J., Hviid, Lars, Narum, D. L., Dicko, A., Fried, M. & Duffy, P. E., 2019, In: Infection and Immunity. 87, 7, 14 p., e00865-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    High frequencies of tumor-infiltrating and circulating γδ T cells in endemic Burkitt lymphoma patients

    Smith-Togobo, C., Quintana Varon, Maria del Pilar, Ofori, M. F. & Hviid, Lars, 2019, In: American Journal of Tropical Medicine and Hygiene. 101, S5, p. 563-563 1830.

    Research output: Contribution to journalConference abstract in journalResearch

  42. Published

    Human Vδ1+ T cells in the immune response to Plasmodium falciparum infection

    Hviid, Lars, Smith-Togobo, C. & Willcox, B. E., 2019, In: Frontiers in Immunology. 10, 5 p., 259.

    Research output: Contribution to journalReviewResearchpeer-review

  43. Published

    Looking for needles in the Plasmodial haystack

    Hviid, Lars, 2019, In: mSphere. 4, 2, 3 p., e00146-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Reliable cell and tissue morphology-based diagnosis of endemic Burkitt lymphoma in resource-constrained settings in Ghana

    Smith-Togobo, C., Pedersen, Mette Ølgod, Jensen, S. G., Duduyemi, B., Gyasi, R. K., Ofori, M. F., Paintsil, V., Renner, L., Nørgaard, P. & Hviid, Lars, 2019, In: BMC Cancer. 19, 7 p., 1270.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 2020
  46. Published

    In vitro selection for adhesion of Plasmodium falciparum-infected erythrocytes to ABO antigens does not affect PfEMP1 and RIFIN expression

    van der Puije, W., Wang, Christian William, Sudharson, S., Hempel, C., Olsen, Rebecca Wendelboe, Dalgaard, Nanna, Ofori, M. F., Hviid, Lars, Kurtzhals, Jørgen & Staalsø, Trine, 2020, In: Scientific Reports. 10, 1, p. 12871 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Acquisition and decay of IgM and IgG responses to merozoite antigens after Plasmodium falciparum malaria in Ghanaian children

    Walker, Melanie Rose, Knudsen, Anne Schlitterlau, Partey, Frederica Dedo, Bassi, Maria Rosaria, Frank, A. M., Castberg, F. C., Sarbah, E. W., Ofori, M. F., Hviid, Lars & Barfod, Lea Klingenberg, 2020, In: PLoS ONE. 15, 12, p. e0243943

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Binding of human serum proteins to Plasmodium falciparum-infected erythrocytes and its association with malaria clinical presentation

    Lopez-Perez, Mary, van der Puije, W., Castberg, F. C., Ofori, M. F. & Hviid, Lars, 2020, In: Malaria Journal. 19, 1, 362.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1-based vaccines to prevent it

    Jensen, Anja Ramstedt, Adams, Yvonne & Hviid, Lars, 2020, In: Immunological Reviews. 293, 1, p. 230-252

    Research output: Contribution to journalReviewResearchpeer-review

  50. Published

    Endemic Burkitt lymphoma - an aggressive childhood cancer linked to Plasmodium falciparum exposure, but not to exposure to other malaria parasites

    Quintana Varon, Maria del Pilar, Smith-Togobo, C., Moormann, A. & Hviid, Lars, 2020, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 128, 2, p. 129-135

    Research output: Contribution to journalReviewResearchpeer-review

  51. Published

    Precipitated malaria: It never rains but it pours

    Hviid, Lars, 2020, In: Trends in Parasitology. 36, 9, p. 721-723 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  52. Published

    Measuring naturally acquired phagocytosis-inducing antibodies to Plasmodium falciparum parasites by a flow cytometry-based assay

    Quintana Varon, Maria del Pilar, Anabire, N. G. & Hviid, Lars, 6 Aug 2020, In: Journal of visualized experiments : JoVE. 162, e61538.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. 2021
  54. Published

    Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination

    Larsen, M. D., Lopez-Perez, Mary, Dickson, E. K., Ampomah, P., Tuikue Ndam, N., Nouta, J., Koeleman, C. A. M., Ederveen, A. L. H., Mordmüller, B., Salanti, Ali, Nielsen, Morten Agertoug, Massougbodji, A., van der Schoot, C. E., Ofori, M. F., Wuhrer, M., Hviid, Lars & Vidarsson, G., 2021, In: Nature Communications. 12, 5838.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Heart failure associated with imported malaria: A nationwide Danish cohort study

    Brainin, P., Mohr, G. H., Modin, D., Claggett, B., Silvestre, O. M., Shah, A., Vestergaard, L. S., Jensen , Jens-Ulrik Stæhr , Hviid, Lars, Torp-Pedersen, Christian, Køber, Lars Valeur, Solomon, S., Schou, Morten, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2021, In: ESC heart failure. 8, 5, p. 3521-3529

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    PfEMP1-specific immunoglobulin G reactivity among Beninese pregnant women with sickle cell trait

    Lopez-Perez, Mary, Viwami, F., Seidu, Zakaria, Jensen, Anja Ramstedt, Doritchamou, J., Ndam, N. T. & Hviid, Lars, 2021, In: Open Forum Infectious Diseases. 8, 12, ofab527.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Suitability of IgG responses to multiple Plasmodium falciparum antigens as markers of transmission intensity and pattern

    Kyei-Baafour, E., Oppong, M., Kusi, K. A., Frempong, A. F., Aculley, B., Arthur, F. K. N., Tiendrebeogo, R. W., Singh, S. K., Theisen, Michael, Kweku, M., Adu, B., Hviid, Lars & Ofori, M. F., 2021, In: PLoS ONE. 16, 4, e0249936.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. 2022
  59. Published

    Analysis by flow cytometry of α2-macroglobulin and nonimmune IgM-binding to Plasmodium falciparum-infected erythrocytes

    Hviid, Lars & Lopez-Perez, Mary, 2022, Malaria Immunology: Targeting the Surface of Infected Erythrocytes. Humana Press, Vol. 2470. p. 435-444 10 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  60. Published

    Analysis of allelic cross-reactivity of monoclonal IgG antibodies by a multiplexed reverse FluoroSpot assay

    Hoffmann-Veltung, H., Anabire, Nsoh Godwin, Ofori, M. F., Janhmatz, P., Ahlborg, N., Hviid, Lars & Quintana Varon, Maria del Pilar, 2022, In: eLife. 11, p. e79245

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 3620