Lars Hviid
Professor
Centre for Medical Parasitology
CMP
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-11-TR4
Member of:
SURFACE team
- 2004
- Published
Compounds useful in the diagnosis and treatment of pregnancy-associated malaria
Theander, Thor Grundtvig, Salanti, Ali, Hviid, Lars, Staalsø, Trine, Jensen, Anja Ramstedt, Lavstsen, Thomas & Dahlbäck, M., 2004, Patent No. WO2004067559 A1, Priority date 27 Jan 2003, Priority No. WO2004067559 A1Research output: Patent
- Published
Evidence for the involvement of VAR2CSA in pregnancy-associated malaria
Salanti, Ali, Dahlbäck, M., Turner, Louise, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Magistrado, P., Jensen, Anja Ramstedt, Lavstsen, Thomas, Ofori, M. F., Marsh, K., Hviid, Lars & Theander, Thor Grundtvig, 2004, In: Journal of Experimental Medicine. 200, 9, p. 1197-203 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Geographical and temporal conservation of antibody recognition of Plasmodium falciparum variant surface antigens
Nielsen, Morten Agertoug, Vestergaard, L. S., Lusingu, J., Kurtzhals, Jørgen, Giha, H. A., Grevstad, B., Goka, B. Q., Lemnge, M. M., Jensen, J. B., Akanmori, B. D., Theander, Thor Grundtvig, Staalsoe, T. & Hviid, Lars, 2004, In: Infection and Immunity. 72, 6, p. 3531-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intermittent preventive sulfadoxine-pyrimethamine treatment of primigravidae reduces levels of plasma immunoglobulin G, which protects against pregnancy-associated Plasmodium falciparum malaria
Staalsoe, T., Shulman, C. E., Dorman, E. K., Kawuondo, K., Marsh, K. & Hviid, Lars, 2004, In: Infection and Immunity. 72, 9, p. 5027-30 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Malaria immunity in infants: a special case of a general phenomenon?
Hviid, Lars & Staalsoe, T., 2004, In: Trends in Parasitology. 20, 2, p. 66-72 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The immuno-epidemiology of pregnancy-associated Plasmodium falciparum malaria: a variant surface antigen-specific perspective
Hviid, Lars, 2004, In: Parasite Immunology. 26, 11-12, p. 477-86 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variant surface antigen-specific IgG and protection against clinical consequences of pregnancy-associated Plasmodium falciparum malaria
Staalsoe, T., Shulman, C. E., Bulmer, J. N., Kawuondo, K., Marsh, K. & Hviid, Lars, 2004, In: Lancet. 363, 9405, p. 283-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variant surface antigens, virulence genes and the pathogenesis of malaria
Deitsch, K. W. & Hviid, Lars, 2004, In: Trends in Parasitology. 20, 12, p. 562-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Differential induction of immunoglobulin G to Plasmodium falciparum variant surface antigens during the transmission season in Daraweesh, Sudan
Nielsen, Morten Agertoug, Grevstad, B., A-Elgadir, T. M. E., Kurtzhals, Jørgen, Giha, H., Staalsoe, T., Hviid, Lars & Theander, Thor Grundtvig, 2005, In: Journal of Infectious Diseases. 192, 3, p. 520-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of pregnancy and intensity of Plasmodium falciparum transmission on immunoglobulin G subclass responses to variant surface antigens
Megnekou, R., Staalsoe, T., Taylor, D. W., Leke, R. & Hviid, Lars, 2005, In: Infection and Immunity. 73, 7, p. 4112-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of Plasmodium falciparum erythrocyte membrane protein 1 in experimentally infected humans
Lavstsen, Thomas, Magistrado, P., Hermsen, C. C., Salanti, Ali, Jensen, Anja Ramstedt, Sauerwein, R., Hviid, Lars, Theander, Thor Grundtvig & Staalsoe, T., 2005, In: Malaria Journal. 4, 1, p. 21Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal vitamin A supplementation and immunity to malaria in pregnancy in Ghanaian primigravids
Cox, S. E., Staalsoe, T., Arthur, P., Bulmer, J. N., Tagbor, H., Hviid, Lars, Frost, C., Riley, E. M. & Kirkwood, B. R., 2005, In: Tropical Medicine & International Health. 10, 12, p. 1286-97 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Naturally acquired immunity to Plasmodium falciparum malaria in Africa
Hviid, Lars, 2005, In: Acta Tropica. 95, 3, p. 270-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid acquisition of isolate-specific antibodies to chondroitin sulfate A-adherent Plasmodium falciparum isolates in Ghanaian primigravidae
Cox, S. E., Staalsoe, T., Arthur, P., Bulmer, J. N., Hviid, Lars, Yeboah-Antwi, K., Kirkwood, B. R. & Riley, E. M., 2005, In: Infection and Immunity. 73, 5, p. 2841-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Baculovirus-expressed constructs induce immunoglobulin G that recognizes VAR2CSA on Plasmodium falciparum-infected erythrocytes
Barfod, Lea Klingenberg, Nielsen, Morten Agertoug, Turner, Louise, Dahlbäck, M., Jensen, Anja Ramstedt, Hviid, Lars, Theander, Thor Grundtvig & Salanti, Ali, 2006, In: Infection and Immunity. 74, 7, p. 4357-60 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasmodium falciparum parasites expressing pregnancy-specific variant surface antigens adhere strongly to the choriocarcinoma cell line BeWo
Haase, R. N., Megnekou, R., Lundquist, M., Ofori, M. F., Hviid, Lars & Staalsoe, T., 2006, In: Infection and Immunity. 74, 5, p. 3035-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epitope mapping and topographic analysis of VAR2CSA DBL3X involved in P. falciparum placental sequestration
Dahlbäck, M., Rask, T. S., Andersen, P. H., Nielsen, Morten Agertoug, Ndam, N. T., Resende, M., Turner, Louise, Deloron, P., Hviid, Lars, Lund, O., Pedersen, A. G., Theander, Thor Grundtvig & Salanti, Ali, 2006, In: PLoS Pathogens. 2, 11, p. e124Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Late recrudescence of Plasmodium falciparum malaria in pregnancy
Hviid, Lars & Staalsoe, T., 2006, In: International Journal of Infectious Diseases. 10, 5, p. 412Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Le paludisme chez la femme enceinte
Hviid, Lars, 2006, In: Medecine Tropicale. 66, 2, p. 130-2 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Levels of plasma immunoglobulin G with specificity against the cysteine-rich interdomain regions of a semiconserved Plasmodium falciparum erythrocyte membrane protein 1, VAR4, predict protection against malarial anemia and febrile episodes
Lusingu, J. P. A., Jensen, Anja Ramstedt, Vestergaard, L. S., Minja, D. T., Dalgaard, M. B., Gesase, S., Mmbando, B. P., Kitua, A. Y., Lemnge, M. M., Cavanagh, D., Hviid, Lars & Theander, Thor Grundtvig, 2006, In: Infection and Immunity. 74, 5, p. 2867-75 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Plasmodium falciparum: VAR2CSA expressed during pregnancy-associated malaria is partially resistant to proteolytic cleavage by trypsin
Nielsen, Morten Agertoug, Resende, M., Alifrangis, Michael, Turner, Louise, Hviid, Lars, Theander, Thor Grundtvig & Salanti, Ali, 2007, In: Experimental Parasitology. 117, 1, p. 1-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adhesion specificities of Plasmodium falciparum-infected erythrocytes involved in the pathogenesis of pregnancy-associated malaria
Hviid, Lars, 2007, In: American Journal of Pathology. 170, 6, p. 1817-9 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasites
Dahlbäck, M., Lavstsen, Thomas, Salanti, Ali, Hviid, Lars, Arnot, D. E., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2007, In: Malaria Journal. 6, p. 78Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Developing Plasmodium falciparum malaria vaccines for populations living in areas with stable parasite transmission
Hviid, Lars & Theander, Thor Grundtvig, 2007, In: International Journal of Biotechnology. 9, 3/4, p. 292-300 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of vaccines against Plasmodium falciparum malaria: taking lessons from naturally acquired protective immunity
Hviid, Lars, 2007, In: Microbes and Infection. 9, 6, p. 772-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA
Barfod, Lea Klingenberg, Bernasconi, N. L., Dahlbäck, M., Jarrossay, D., Andersen, P. H., Salanti, Ali, Ofori, M. F., Turner, Louise, Resende, M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sallusto, F., Lanzavecchia, A. & Hviid, Lars, 2007, In: Molecular Microbiology. 63, 2, p. 335-47 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malaria
Magistrado, P. A., Lusingu, J., Vestergaard, L. S., Lemnge, M., Lavstsen, Thomas, Turner, Louise, Hviid, Lars, Jensen, Anja Ramstedt & Theander, Thor Grundtvig, 2007, In: Infection and Immunity. 75, 5, p. 2415-20 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Malaria in pregnancy: pathogenesis and immunity
Rogerson, S. J., Hviid, Lars, Duffy, P. E., Leke, R. F. G. & Taylor, D. W., 2007, In: Lancet Infectious Diseases. 7, 2, p. 105-17 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selective activation of TCR-G¿ cells in endemic Burkitt's lymphoma
Futagbi, G., Welbeck, J. E., Tetteh, J. K. A., Hviid, Lars & Akanmori, B. D., 2007, In: Malaria Journal. 6, p. 69Research output: Contribution to journal › Journal article › Research › peer-review
- Published
VAR2CSA and protective immunity against pregnancy-associated Plasmodium falciparum malaria
Hviid, Lars & Salanti, Ali, 2007, In: Parasitology. 134, Pt 13, p. 1871-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vß profiles in African children with acute cerebral or uncomplicated malaria: very focused changes among a remarkable global stability
Loizon, S., Boeuf, P., Tetteh, J. K. A., Goka, B., Obeng-Adjei, G., Kurtzhals, J. A. L., Rogier, C., Akanmori, B. D., Mercereau-Puijalon, O., Hviid, Lars & Behr, C., 2007, In: Microbes and Infection. 9, 11, p. 1252-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
CD36 selection of 3D7 Plasmodium falciparum associated with severe childhood malaria results in reduced VAR4 expression
Magistrado, P., Staalsoe, T., Theander, Thor Grundtvig, Hviid, Lars & Jensen, Anja Ramstedt, 2008, In: Malaria Journal. 7, 1, p. 204Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differences in human antibody reactivity to Plasmodium falciparum variant surface antigens are dependent on age and malaria transmission intensity in northeastern Tanzania
Vestergaard, L. S., Lusingu, J. P., Nielsen, Morten Agertoug, Mmbando, B. P., Dodoo, D., Akanmori, B. D., Alifrangis, Michael, Bygbjerg, Ib Christian, Lemnge, M. M., Staalsoe, T., Hviid, Lars & Theander, Thor Grundtvig, 2008, In: Infection and Immunity. 76, 6, p. 2706-14 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Malaria vaccines: immunity, models and monoclonal antibodies
Hviid, Lars & Barfod, Lea Klingenberg, 2008, In: Trends in Parasitology. 24, 9, p. 392-395 3 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
VAR2CSA expression on the surface of placenta-derived Plasmodium falciparum-infected erythrocytes
Magistrado, P., Salanti, Ali, Tuikue Ndam, N. G., Mwakalinga, S. B., Resende, M., Dahlbäck, M., Hviid, Lars, Lusingu, J., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2008, In: Journal of Infectious Diseases.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Human monoclonal IgG selection of Plasmodium falciparum for the expression of placental malaria-specific variant surface antigens
Soerli, J., Barfod, Lea Klingenberg, Lavstsen, Thomas, Bernasconi, N. L., Lanzavecchia, A. & Hviid, Lars, 2009, In: Parasite Immunology. 31, 6, p. 341-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pregnancy-associated malaria in a rural community of Ghana
Ofori, M., Ansah, E., Agyepong, I., Ofori-Adjei, D., Hviid, Lars & Akanmori, B., 2009, In: Ghana Medical Journal. 43, 1, p. 13-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unraveling the impact of malaria exposure before birth
Hviid, Lars, 2009, In: PLoS Medicine. 6, 7, p. e1000117Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variant-specific immunity to Plasmodium berghei in pregnant mice
Megnekou, R., Hviid, Lars & Staalsoe, T., 2009, In: Infection and Immunity. 77, 5, p. 1827-34 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Chondroitin sulfate A-adhering Plasmodium falciparum-infected erythrocytes express functionally important antibody epitopes shared by multiple variants
Barfod, Lea Klingenberg, Dobrilovic, T., Magistrado, P., Khunrae, P., Viwami, F., Bruun, J., Dahlbäck, M., Bernasconi, N. L., Fried, M., John, D., Duffy, P. E., Salanti, Ali, Lanzavecchia, A., Lim, C. T., Ndam, N. T., Higgins, M. K. & Hviid, Lars, 2010, In: Journal of Immunology. 185, 12, p. 7553-61 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian children
Cham, G. K. K., Turner, Louise, Kurtis, J. D., Mutabingwa, T., Fried, M., Jensen, Anja Ramstedt, Lavstsen, Thomas, Hviid, Lars, Duffy, P. E. & Theander, Thor Grundtvig, 2010, In: Infection and Immunity. 78, 11, p. 4653-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immune selection and within-host competition can structure the repertoire of variant surface antigens in Plasmodium falciparum -a mathematical model
van Noort, S. P., Nunes, M. C., Weedall, G. D., Hviid, Lars & Gomes, M. G. M., 2010, In: PLoS ONE. 5, 3, p. e9778Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Of mice and women: rodent models of placental malaria
Hviid, Lars, Marinho, C. R. F., Staalsø, Trine & Penha-Gonçalves, C., 2010, In: Trends in Parasitology. 26, 8, p. 412-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The kinetics of antibody binding to Plasmodium falciparum VAR2CSA PfEMP1 antigen and modelling of PfEMP1 antigen packing on the membrane knobs
Joergensen, L. M., Salanti, Ali, Dobrilovic, T., Barfod, Lea Klingenberg, Hassenkam, Tue, Theander, Thor Grundtvig, Hviid, Lars & Arnot, D. E., 2010, In: Malaria Journal. 9, 1, p. 100Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of Plasmodium falciparum variant surface antigens in protective immunity and vaccine development
Hviid, Lars, 2010, In: Human Vaccines. 6, 1, p. 84-89 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Evasion of immunity to Plasmodium falciparum malaria by IgM masking of protective IgG epitopes in infected erythrocyte surface-exposed PfEMP1
Barfod, Lea Klingenberg, Dalgaard, M. B., Pleman, S. T., Ofori, M. F., Pleass, R. J. & Hviid, Lars, 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 30, p. 12485-90 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The case for PfEMP1-based vaccines to protect pregnant women against Plasmodium falciparum malaria
Hviid, Lars, 2011, In: Expert Review of Vaccines. 10, 10, p. 1405-14 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Aligned hemozoin crystals in curved clusters in malarial red blood cells revealed by nanoprobe X-ray Fe fluorescence and diffraction
Kapishnikov, S., Berthing, T., Hviid, Lars, Dierolf, M., Menzel, A., Pfeiffer, F., Als-Nielsen, Jens & Leiserowitz, L., 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 28, p. 11184-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insights into deregulated TNF and IL-10 production in malaria: implications for understanding severe malarial anaemia
Boeuf, P. S., Loizon, S., Awandare, G. A., Tetteh, J. K., Addae, M. M., Adjei, G. O., Goka, B., Kurtzhals, Jørgen, Puijalon, O., Hviid, Lars, Akanmori, B. D. & Behr, C., 2012, In: Malaria Journal. 11, 1, p. 253Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The density of knobs on Plasmodium falciparum-infected erythrocytes depends on developmental age and varies among isolates
Quadt, K. A., Barfod, Lea Klingenberg, Andersen, D., Bruun, J., Gyan, B., Hassenkam, Tue, Ofori, M. F. & Hviid, Lars, 2012, In: P L o S One. 7, 9, p. e45658Research output: Contribution to journal › Journal article › Research › peer-review
ID: 3620
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3614
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Kinetics of B Cell responses to Plasmodium falciparum erythrocyte membrane protein 1 in Ghanaian women naturally exposed to malaria parasites
Research output: Contribution to journal › Journal article › Research › peer-review
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2133
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Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites
Research output: Contribution to journal › Journal article › Research › peer-review
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2079
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B-cell responses to pregnancy-restricted and -unrestricted Plasmodium falciparum erythrocyte membrane protein 1 antigens in Ghanaian women naturally exposed to malaria parasites
Research output: Contribution to journal › Journal article › Research › peer-review
Published