Thor Grundtvig Theander
Professor
Centre for Medical Parasitology
Blegdamsvej 3, 2200 København N, Building: 07-11-17
CMP
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-11-TR4
Member of:
CMP-BIOENGINEERING
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Compounds useful in the diagnosis and treatment of pregnancy-associated malaria
Theander, Thor Grundtvig, Salanti, Ali, Hviid, Lars, Staalsø, Trine, Jensen, Anja Ramstedt, Lavstsen, Thomas & Dahlbäck, M., 2004, Patent No. WO2004067559 A1, Priority date 27 Jan 2003, Priority No. WO2004067559 A1Research output: Patent
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Parasitologi
Theander, Thor Grundtvig & Kurtzhals, Jørgen, 2008, Klinisk Mikrobiologi og Infektionsmedicin. Høiby, N. & Skinhøj, P. (eds.). København: FADL's Forlag, Vol. 11. p. 481-537 56 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Activation of CD8-positive suppressor cells during the malaria season
Theander, Thor Grundtvig, Hviid, Lars, Abu-Zeid, Y. A., Abdulhadi, N. H., Saeed, B. O., Jakobsen, P. H., Jepsen, S., Bayoumi, R. A. & Jensen, J. B., 1993, In: Immunology and Infectious Diseases. 3, p. 97-102Research output: Contribution to journal › Journal article › Research › peer-review
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Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial
RTS,S Clinical Trials Partnership, R. C. T. P., 4 Jul 2015, In: Lancet. 386, 9988, p. 31-45 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prospects and challenges regarding Plasmodium falciparum erythrocyte membrane protein I as vaccine antigens
Theander, Thor Grundtvig, 2008, In: International Journal for Parasitology. 38, Suppl. 1, p. S23-S23Research output: Contribution to journal › Journal article › Research
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Efficacy and Safety of the RTS,S/AS01 Malaria Vaccine during 18 Months after Vaccination: A Phase 3 Randomized, Controlled Trial in Children and Young Infants at 11 African Sites
Theander, Thor Grundtvig, Lusingu, J. P. A. & RTS,S Clinical Trials Partnership, R. C. T. P., Jul 2014, In: P L o S Medicine (Online). 11, 7, p. 1-24 24 p., e1001685.Research output: Contribution to journal › Journal article › Research › peer-review
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Selection of glutamate-rich protein long synthetic peptides for vaccine development: antigenicity and relationship with clinical protection and immunogenicity
Theisen, M., Dodoo, D., Toure-Balde, A., Soe, S., Corradin, G., Koram, K. K., Kurtzhals, Jørgen, Hviid, Lars, Theander, Thor Grundtvig, Akanmori, B., Ndiaye, M. & Druilhe, P., 2001, In: Infection and Immunity. 69, 9, p. 5223-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prevalence of Single Nucleotide Polymorphisms in the Plasmodium falciparum Multidrug Resistance Gene (Pfmdr-1) in Korogwe District in Tanzania Before and After Introduction of Artemisinin-Based Combination Therapy
Thomsen, T. T., Ishengoma, D. S., Mmbando, B. P., Lusingu, J. P., Vestergaard, L. S., Theander, Thor Grundtvig, Lemnge, M. M., Bygbjerg, Ib Christian & Alifrangis, Michael, 1 Dec 2011, In: American Journal of Tropical Medicine and Hygiene. 85, 6, p. 979-83 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bacterial superglue enables easy development of efficient virus-like particle based vaccines
Thrane, Susan, Janitzek, C. M., Matondo, S., dos Santos Marques Resende, M., Gustavsson, Tobias, De Jongh, W. A., Clemmensen, S., Roeffen, W., van de Vegte-Bolmer, M., van Gemert, G. J., Sauerwein, R., Schiller, J. T., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Salanti, Ali & Sander, Adam F. , 27 Apr 2016, In: Journal of Nanobiotechnology. 14, 16 p., 30.Research output: Contribution to journal › Journal article › Research › peer-review
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A vaccine displaying a trimeric influenza-A HA stem protein on capsid-like particles elicits potent and long-lasting protection in mice
Thrane, Susan, Aves, Kara-Lee, Uddbäck, Ida Elin Maria, Janitzek, C. M., Han, J., Yang, Y. R., Ward, A. B., Theander, Thor Grundtvig, Nielsen, Morten Agertoug, Salanti, Ali, Thomsen, Allan Randrup, Christensen, Jan Pravsgaard & Sander, Adam F. , 2020, In: Vaccines. 8, 3, 389.Research output: Contribution to journal › Journal article › Research › peer-review
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A novel virus-like particle based vaccine platform displaying the placental malaria antigen VAR2CSA
Thrane, Susan, Janitzek, C. M., Agerbæk, Mette Ørskov, Ditlev, S. B., dos Santos Marques Resende, M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Salanti, Ali & Sander, Adam F. , 2015, In: PloS one. 10, 11, 16 p., e0143071.Research output: Contribution to journal › Journal article › Research › peer-review
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Dynamics of anti-VAR2CSA immunoglobulin G response in a cohort of senegalese pregnant women
Tuikue Ndam, N. G., Salanti, Ali, Le-Hesran, J., Cottrell, G., Fievet, N., Turner, Louise, Sow, S., Dangou, J., Theander, Thor Grundtvig & Deloron, P., 2006, In: Journal of Infectious Diseases. 193, 5, p. 713-20 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Parasites causing cerebral falciparum malaria bind multiple endothelial receptors and express EPCR and ICAM-1-binding PfEMP1
Tuikue Ndam, N., Moussiliou, A., Lavstsen, Thomas, Kamaliddin, C., Jensen, Anja Ramstedt, Mama, A., Tahar, R., Wang, Christian William, Jespersen, Jakob Schmidt, Alao, J. M., Gamain, B., Theander, Thor Grundtvig & Deloron, P., 2017, In: The Journal of Infectious Diseases. 215, 12, p. 1918-1925 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum transcriptome analysis reveals pregnancy malaria associated gene expression
Tuikue Ndam, N., Bischoff, E., Proux, C., Lavstsen, Thomas, Salanti, Ali, Guitard, J., Nielsen, Morten Agertoug, Coppée, J., Gaye, A., Theander, Thor Grundtvig, David, P. H. & Deloron, P., 2008, In: PLoS ONE. 3, 3, p. e1855Research output: Contribution to journal › Journal article › Research › peer-review
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High level of var2csa transcription by Plasmodium falciparum isolated from the placenta
Tuikue Ndam, N. G., Salanti, Ali, Bertin, G., Dahlbäck, M., Fievet, N., Turner, Louise, Gaye, A., Theander, Thor Grundtvig & Deloron, P., 2005, In: Journal of Infectious Diseases. 192, 2, p. 331-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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IgG antibodies to endothelial protein C receptor-binding Cysteine-rich interdomain region domains of Plasmodium falciparum erythrocyte membrane protein 1 are acquired early in life in individuals exposed to malaria
Turner, Louise, Lavstsen, Thomas, Mmbando, B. P., Wang, Christian William, Magistrado, P. A., Vestergaard, L. S., Ishengoma, D. S., Minja, D. T. R., Lusingu, J. P. & Theander, Thor Grundtvig, Aug 2015, In: Infection and Immunity. 83, 8, p. 3096-103 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Immunization with Recombinant Plasmodium falciparum Erythrocyte Membrane Protein 1 CIDRα1 Domains Induces Domain Subtype Inhibitory Antibodies
Turner, Louise, Theander, Thor Grundtvig & Lavstsen, Thomas, 2018, In: Infection and Immunity. 86, 11, 11 p., e00435-18.Research output: Contribution to journal › Journal article › Research › peer-review
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Severe malaria is associated with parasite binding to endothelial protein C receptor
Turner, Louise, Lavstsen, Thomas, Berger, S. S., Wang, Christian William, Petersen, J. E. V., Avril, M., Brazier, A. J., Freeth, J., Jespersen, Jakob Schmidt, Nielsen, Morten Agertoug, Magistrado, P., Lusingu, J., Smith, J. D., Higgins, M. K. & Theander, Thor Grundtvig, 27 Jun 2013, In: Nature. 498, 7455, p. 502-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibodies against PfEMP1, RIFIN, MSP3 and GLURP are acquired during controlled Plasmodium falciparum malaria infections in naïve volunteers
Turner, Louise, Wang, Christian William, Lavstsen, Thomas, Mwakalinga, S. B., Sauerwein, R. W., Hermsen, C. C. & Theander, Thor Grundtvig, 2011, In: P L o S One. 6, 12, p. e29025Research output: Contribution to journal › Journal article › Research › peer-review
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Comparative analysis of spike-specific IgG Fc glycoprofiles elicited by adenoviral, mRNA, and protein-based SARS-CoV-2 vaccines
Van Coillie, J., Pongracz, T., Šuštić, T., Wang, W., Nouta, J., Le Gars, M., Keijzer, S., Linty, F., Cristianawati, O., Keijser, J. B. D., Visser, R., van Vught, L. A., Slim, M. A., van Mourik, N., Smit, M. J., Sander, A., Schmidt, D. E., Steenhuis, M., Rispens, T., Nielsen, M. A. & 31 others, , 2023, In: iScience. 26, 9, p. 1-15 107619.Research output: Contribution to journal › Journal article › Research › peer-review
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Differences in human antibody reactivity to Plasmodium falciparum variant surface antigens are dependent on age and malaria transmission intensity in northeastern Tanzania
Vestergaard, L. S., Lusingu, J. P., Nielsen, Morten Agertoug, Mmbando, B. P., Dodoo, D., Akanmori, B. D., Alifrangis, Michael, Bygbjerg, Ib Christian, Lemnge, M. M., Staalsoe, T., Hviid, Lars & Theander, Thor Grundtvig, 2008, In: Infection and Immunity. 76, 6, p. 2706-14 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Insect cells are superior to Escherichia coli in producing malaria proteins inducing IgG targeting PfEMP1 on infected erythrocytes
Victor, M. E., Bengtsson, A., Andersen, G., Bengtsson, D., Lusingu, J. P., Vestergaard, L. S., Arnot, D. E., Theander, Thor Grundtvig, Joergensen, L. & Jensen, Anja Ramstedt, 2010, In: Malaria Journal. 9, p. 325Research output: Contribution to journal › Journal article › Research › peer-review
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Evidence for in vitro and in vivo expression of the conserved VAR3 (type 3) plasmodium falciparum erythrocyte membrane protein 1
Wang, Christian William, Lavstsen, Thomas, Bengtsson, D. C., Magistrado, P. A., Berger, S. S., Marquard, A. M., Alifrangis, Michael, Lusingu, J. P., Theander, Thor Grundtvig & Turner, Louise, 2012, In: Malaria Journal. 11, 1, p. 129Research output: Contribution to journal › Journal article › Research › peer-review
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The Plasmodium falciparum var gene transcription strategy at the onset of blood stage infection in a human volunteer
Wang, Christian William, Hermsen, C. C., Sauerwein, R. W., Arnot, D. E., Theander, Thor Grundtvig & Lavstsen, Thomas, 2009, In: Parasitology International. 58, 4, p. 478-80 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Preferential transcription of conserved rif genes in two phenotypically distinct Plasmodium falciparum parasite lines
Wang, Christian William, Magistrado, P. A., Nielsen, Morten Agertoug, Theander, Thor Grundtvig & Lavstsen, Thomas, 2009, In: International Journal for Parasitology. 39, 6, p. 655-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of a major rif transcript common to gametocytes and sporozoites of Plasmodium falciparum
Wang, Christian William, Mwakalinga, S. B., Sutherland, C. J., Schwank, S., Sharp, S., Hermsen, C. C., Sauerwein, R. W., Theander, Thor Grundtvig & Lavstsen, Thomas, 2010, In: Malaria Journal. 9, 1, p. 147Research output: Contribution to journal › Journal article › Research › peer-review
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Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding
Wang, Kaituo, Dagil, Robert, Lavstsen, Thomas, Misra, S. K., Spliid, C. B., Wang, Y., Gustavsson, Tobias, Sandoval, D. R., Vidal-Calvo, E. E., Choudhary, Swati, Agerbæk, Mette Ørskov, Lindorff-Larsen, Kresten, Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sharp, J. S., Clausen, Thomas Mandel, Gourdon, Pontus Emanuel & Salanti, Ali, 2021, In: Nature Communications. 12, 1, 10 p., 2956.Research output: Contribution to journal › Journal article › Research › peer-review
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The antileishmanial activity of novel oxygenated chalcones and their mechanism of action
Zhai, L., Chen, M., Blom, J., Theander, Thor Grundtvig, Christensen, Søren Brøgger & Kharazmi, A., 1999, In: Journal of Antimicrobial Chemotherapy. 43, 6, p. 793-803 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11256
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Real-time and label free determination of ligand binding-kinetics to primary cancer tissue specimens; a novel tool for the assessment of biomarker targeting
Research output: Contribution to journal › Journal article › Research › peer-review
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564
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Bacterial superglue enables easy development of efficient virus-like particle based vaccines
Research output: Contribution to journal › Journal article › Research › peer-review
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514
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Placental sequestration of Plasmodium falciparum malaria parasites is mediated by the interaction between VAR2CSA and chondroitin sulfate A on syndecan-1
Research output: Contribution to journal › Journal article › Research › peer-review
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