Michael Theisen
Professor
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Human blood neutrophils generate ROS through FcγR-signaling to mediate protection against febrile P. falciparum malaria
Ofori, Ebenezer Addo, Garcia-Senosiain, A., Naghizadeh, Mohammad, Kana, Ikhlaq Hussain, Dziegiel, Morten Hanefeld, Adu, B., Singh, S. & Theisen, Michael, 2023, In: Communications Biology . 6, 743.Research output: Contribution to journal › Journal article › Research › peer-review
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Distinct patterns of blood-stage parasite antigens detected by plasma IgG subclasses from individuals with different level of exposure to Plasmodium falciparum infections
Olesen, C. H., Brahimi, K., Vandahl, B., Lousada-Dietrich, S., Jogdand, P. S., Vestergaard, L. S., Dodoo, D., Hojrup, P., Christiansen, M., Larsen, S. O., Singh, S. & Theisen, Michael, 2010, In: Malaria Journal. 9, 1, p. 296Research output: Contribution to journal › Journal article › Research › peer-review
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A novel Pfs38 protein complex on the surface of Plasmodium falciparum blood-stage merozoites
Paul, G., Deshmukh, A., Kaur, I., Rathore, S., Dabral, S., Panda, A., Singh, S. K., Mohmmed, A., Theisen, Michael & Malhotra, P., 16 Feb 2017, In: Malaria Journal. 16, 1, 15 p., 79.Research output: Contribution to journal › Journal article › Research › peer-review
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Protein-protein interaction studies reveal the Plasmodium falciparum merozoite surface protein-1 region involved in a complex formation that binds to human erythrocytes
Paul, G., Deshmukh, A., Kumar Chourasia, B., Kalamuddin, M., Panda, A., Kumar Singh, S., Gupta, P. K., Mohmmed, A., Chauhan, V. S., Theisen, Michael & Malhotra, P., 2018, In: Biochemical Journal. 475, 6, p. 1197-1209 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Clinical formulation development of Plasmodium falciparum malaria vaccine candidates based on Pfs48/45, Pfs230, and PfCSP
Plieskatt, J., Bang, P., Wood, G. K., Naghizadeh, Mohammad, Singh, S. K., Jore, M. M. & Theisen, Michael, 2024, In: Vaccine. 42, 8, p. 1980-1992Research output: Contribution to journal › Journal article › Research › peer-review
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Antibodies against the Plasmodium falciparum glutamate-rich protein from naturally exposed individuals living in a Brazilian malaria-endemic area can inhibit in vitro parasite growth
Pratt-Riccio, L. R., Bianco, C., Totino, P. R. R., Perce-Da-Silva, D. D. S., Silva, L. A., Riccio, E. K. P., Ennes-Vidal, V., Neves-Ferreira, A. G. C., Perales, J., Da Rocha, S. L. G., Dias-Da-Silva, F., Ferreira-da-Cruz, M. D. F., Daniel-Ribeiro, C. T., De Oliveira-Ferreira, J., Theisen, Michael, Carvalho, L. J. D. M. & Banic, D. M., 2011, In: Memórias do Instituto Oswaldo Cruz. 106 Suppl 1, p. 34-43 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic polymorphisms in the glutamate-rich protein of Plasmodium falciparum field isolates from a malaria-endemic area of Brazil
Pratt-Riccio, L. R., Perce-da-Silva, D. D. S., Lima-Junior, J. D. C., Theisen, Michael, Santos, F., Daniel-Ribeiro, C. T., de Oliveira-Ferreira, J. & Banic, D. M., Jun 2013, In: Memórias do Instituto Oswaldo Cruz. 108, 4, p. 523-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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SURGE complex of Plasmodium falciparum in the rhoptry-neck (SURFIN4.2-RON4-GLURP) contributes to merozoite invasion
Quintana Varon, Maria del Pilar, Ch'ng, J., Zandian, A., Imam, M., Hultenby, K., Theisen, Michael, Nilsson, P., Qundos, U., Moll, K., Chan, S. & Wahlgren, M., 2018, In: PLOS ONE. 13, 8, 25 p., e0201669.Research output: Contribution to journal › Journal article › Research › peer-review
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Transmission-blocking activity of antibodies to Plasmodium falciparum GLURP.10C chimeric protein formulated in different adjuvants
Roeffen, W., Theisen, Michael, van de Vegte-Bolmer, M., van Gemert, G., Arens, T., Andersen, G., Christiansen, M., Sevargave, L., Singh, S. K., Kaviraj, S. & Sauerwein, R., 2015, In: Malaria Journal. 14, 9 p., 443.Research output: Contribution to journal › Journal article › Research › peer-review
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Assessing malaria transmission in a low endemicity area of north-western Peru
Rosas-Aguirre, A., Llanos-Cuentas, A., Speybroeck, N., Cook, J., Contreras-Mancilla, J., Soto, V., Gamboa, D., Pozo, E., Ponce, O. J., Pereira, M. O., Soares, I. S., Theisen, Michael, D'Alessandro, U. & Erhart, A., 2013, In: Malaria Journal. 12, 1, p. 339Research output: Contribution to journal › Journal article › Research › peer-review
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40 Years of Pfs48/45 Research as a Transmission-Blocking Vaccine Target of Plasmodium falciparum Malaria
Sauerwein, R. W., Plieskatt, J. & Theisen, Michael, 2022, In: American Journal of Tropical Medicine and Hygiene. 107, p. 22-26 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular and functional characterization of Fcγ receptor IIIb-ligand interaction: Implications for neutrophil-mediated immune mechanisms in malaria
Simtong, P., Romphruk, A. V., Traum, A., Burg-Roderfeld, M., Bein, G., Jakubowski, K., Dominik, A., Theisen, Michael, Kana, Ikhlaq Hussain, Sachs, U. J. & Santoso, S., 2018, In: Infection and Immunity. 86, 8, e00924-17.Research output: Contribution to journal › Journal article › Research › peer-review
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A reproducible and scalable process for manufacturing a Pfs48/45 based Plasmodium falciparum transmission-blocking vaccine
Singh, S. K., Plieskatt, J., Chourasia, B. K., Fabra-García, A., Garcia-Senosiain, A., Singh, V., Bengtsson, K. L., Reimer, J. M., Sauerwein, R., Jore, M. M. & Theisen, Michael, 2021, In: Frontiers in Immunology. 11, 606266.Research output: Contribution to journal › Journal article › Research › peer-review
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Improving the malaria transmission-blocking activity of a Plasmodium falciparum 48/45 based vaccine antigen by SpyTag/SpyCatcher mediated virus-like display
Singh, S. K., Thrane, Susan, Janitzek, C. M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Theisen, Michael, Salanti, Ali & Sander, Adam F. , 2017, In: Vaccine. 35, 30, p. 3726-3732 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Plasmodium falciparum circumsporozoite protein produced in Lactococcus lactis is pure and stable
Singh, S. K., Plieskatt, J., Chourasia, B. K., Singh, V., Bolscher, J. M., Dechering, K. J., Adu, B., López-Méndez, B., Kaviraj, S., Locke, E., King, C. R. & Theisen, Michael, 2020, In: Journal of Biological Chemistry. 295, 2, p. 403-414 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Preclinical development of a Pfs230-Pfs48/45 chimeric malaria transmission-blocking vaccine
Singh, S. K., Plieskatt, J., Chourasia, B. K., Singh, V., Bengtsson, K. L., Reimer, J. M., van Daalen, R. C., Teelen, K., van de Vegte-Bolmer, M., van Gemert, G., Jore, M. M. & Theisen, Michael, 2021, In: npj Vaccines. 6, 11 p., 120.Research output: Contribution to journal › Journal article › Research › peer-review
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A Plasmodium falciparum 48/45 single epitope R0.6C subunit protein elicits high levels of transmission blocking antibodies
Singh, S. K., Roeffen, W., Andersen, G., Bousema, T., Christiansen, M., Sauerwein, R. & Theisen, Michael, 15 Apr 2015, In: Vaccine. 33, 16, p. 1981-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pfs230 and Pfs48/45 fusion proteins elicit strong transmission-blocking antibody responses against Plasmodium falciparum
Singh, S. K., Thrane, Susan, Chourasia, B. K., Teelen, K., Graumans, W., Stoter, R., van Gemert, G., van de Vegte-Bolmer, M. G., Nielsen, Morten Agertoug, Salanti, Ali, Sander, Adam F. , Sauerwein, R. W., Jore, M. M. & Theisen, Michael, 2019, In: Frontiers in Immunology. 10, 1256.Research output: Contribution to journal › Journal article › Research › peer-review
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Lactococcus lactis provides an efficient platform for production of disulfide-rich recombinant proteins from Plasmodium falciparum
Singh, S. K., Tiendrebeogo, R. W., Chourasia, B. K., Kana, Ikhlaq Hussain, Singh, S. & Theisen, Michael, 2018, In: Microbial Cell Factories. 17, 13 p., 55.Research output: Contribution to journal › Journal article › Research › peer-review
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Construct design, production, and characterization of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine
Singh, S. K., Roeffen, W., Mistarz, U. H., Chourasia, B. K., Yang, F., Rand, Kasper Dyrberg, Sauerwein, R. W. & Theisen, Michael, 2017, In: Microbial Cell Factories. 16, 1, 11 p., 97.Research output: Contribution to journal › Journal article › Research › peer-review
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Cloning and recombinant protein expression in Lactococcus lactis
Singh, S. K., Naghizadeh, Mohammad, Plieskatt, J., Singh, S. & Theisen, Michael, 2023, Advanced Methods in Structural Biology. Sousa, Â. & Passarinha, L. (eds.). Humana Press, p. 3-20 18 p. (Methods in Molecular Biology, Vol. 2652).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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A phase 2b randomized, controlled trial of the efficacy of the GMZ2 malaria vaccine in African children
Sirima, S. B., Mordmüller, B., Milligan, P., Ngoa, U. A., Kironde, F., Atuguba, F., Tiono, A. B., Issifou, S., Kaddumukasa, M., Bangre, O., Flach, C., Christiansen, M., Bang, P., Chilengi, R., Jepsen, S., Kremsner, P. G. & Theisen, Michael, Aug 2016, In: Vaccine. 34, 38, p. 4536-4542 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The candidate blood-stage malaria vaccine P27A induces a robust humoral response in a fast track to the field Phase 1 trial in exposed and nonexposed volunteers
Steiner-Monard, V., Kamaka, K., Karoui, O., Roethlisberger, S., Audran, R., Daubenberger, C., Fayet-Mello, A., Erdmann-Voisin, A., Felger, I., Geiger, K., Govender, L., Houard, S., Huber, E., Mayor, C., Mkindi, C., Portevin, D., Rusch, S., Schmidlin, S., Tiendrebeogo, R. W., Theisen, M. & 9 others, , 2019, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 68, 3, p. 466-474 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity
Stone, W. J. R., Campo, J. J., Ouédraogo, A. L., Meerstein-Kessel, L., Morlais, I., Da, D., Cohuet, A., Nsango, S., Sutherland, C. J., van de Vegte-Bolmer, M., Siebelink-Stoter, R., van Gemert, G-J., Graumans, W., Lanke, K., Shandling, A. D., Pablo, J. V., Teng, A. A., Jones, S., de Jong, R. M., Fabra-García, A. & 14 others, , 8 Feb 2018, In: Nature Communications. 9, 1, 14 p., 558.Research output: Contribution to journal › Journal article › Research › peer-review
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Immunogenicity of a virosomally-formulated Plasmodium falciparum GLURP-MSP3 chimeric protein-based malaria vaccine candidate in comparison to adjuvanted formulations
Tamborrini, M., Stoffel, S. A., Westerfeld, N., Amacker, M., Theisen, Michael, Zurbriggen, R. & Pluschke, G., 2011, In: Malaria Journal. 10, p. 359Research output: Contribution to journal › Journal article › Research › peer-review
ID: 10528769
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Natural antibody responses to Plasmodium falciparum MSP3 and GLURP(R0) antigens are associated with low parasite densities in malaria patients living in the Central Region of Ghana
Research output: Contribution to journal › Journal article › Research › peer-review
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229
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Construct design, production, and characterization of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine
Research output: Contribution to journal › Journal article › Research › peer-review
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209
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Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity
Research output: Contribution to journal › Journal article › Research › peer-review
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