Michael Theisen

Michael Theisen

Professor

Member of:

  • GLURP team


  1. Published

    Human blood neutrophils generate ROS through FcγR-signaling to mediate protection against febrile P. falciparum malaria

    Ofori, Ebenezer Addo, Garcia-Senosiain, A., Naghizadeh, Mohammad, Kana, Ikhlaq Hussain, Dziegiel, Morten Hanefeld, Adu, B., Singh, S. & Theisen, Michael, 2023, In: Communications Biology . 6, 743.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Distinct patterns of blood-stage parasite antigens detected by plasma IgG subclasses from individuals with different level of exposure to Plasmodium falciparum infections

    Olesen, C. H., Brahimi, K., Vandahl, B., Lousada-Dietrich, S., Jogdand, P. S., Vestergaard, L. S., Dodoo, D., Hojrup, P., Christiansen, M., Larsen, S. O., Singh, S. & Theisen, Michael, 2010, In: Malaria Journal. 9, 1, p. 296

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A novel Pfs38 protein complex on the surface of Plasmodium falciparum blood-stage merozoites

    Paul, G., Deshmukh, A., Kaur, I., Rathore, S., Dabral, S., Panda, A., Singh, S. K., Mohmmed, A., Theisen, Michael & Malhotra, P., 16 Feb 2017, In: Malaria Journal. 16, 1, 15 p., 79.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Protein-protein interaction studies reveal the Plasmodium falciparum merozoite surface protein-1 region involved in a complex formation that binds to human erythrocytes

    Paul, G., Deshmukh, A., Kumar Chourasia, B., Kalamuddin, M., Panda, A., Kumar Singh, S., Gupta, P. K., Mohmmed, A., Chauhan, V. S., Theisen, Michael & Malhotra, P., 2018, In: Biochemical Journal. 475, 6, p. 1197-1209 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Clinical formulation development of Plasmodium falciparum malaria vaccine candidates based on Pfs48/45, Pfs230, and PfCSP

    Plieskatt, J., Bang, P., Wood, G. K., Naghizadeh, Mohammad, Singh, S. K., Jore, M. M. & Theisen, Michael, 2024, In: Vaccine. 42, 8, p. 1980-1992

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Antibodies against the Plasmodium falciparum glutamate-rich protein from naturally exposed individuals living in a Brazilian malaria-endemic area can inhibit in vitro parasite growth

    Pratt-Riccio, L. R., Bianco, C., Totino, P. R. R., Perce-Da-Silva, D. D. S., Silva, L. A., Riccio, E. K. P., Ennes-Vidal, V., Neves-Ferreira, A. G. C., Perales, J., Da Rocha, S. L. G., Dias-Da-Silva, F., Ferreira-da-Cruz, M. D. F., Daniel-Ribeiro, C. T., De Oliveira-Ferreira, J., Theisen, Michael, Carvalho, L. J. D. M. & Banic, D. M., 2011, In: Memórias do Instituto Oswaldo Cruz. 106 Suppl 1, p. 34-43 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Genetic polymorphisms in the glutamate-rich protein of Plasmodium falciparum field isolates from a malaria-endemic area of Brazil

    Pratt-Riccio, L. R., Perce-da-Silva, D. D. S., Lima-Junior, J. D. C., Theisen, Michael, Santos, F., Daniel-Ribeiro, C. T., de Oliveira-Ferreira, J. & Banic, D. M., Jun 2013, In: Memórias do Instituto Oswaldo Cruz. 108, 4, p. 523-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    SURGE complex of Plasmodium falciparum in the rhoptry-neck (SURFIN4.2-RON4-GLURP) contributes to merozoite invasion

    Quintana Varon, Maria del Pilar, Ch'ng, J., Zandian, A., Imam, M., Hultenby, K., Theisen, Michael, Nilsson, P., Qundos, U., Moll, K., Chan, S. & Wahlgren, M., 2018, In: PLOS ONE. 13, 8, 25 p., e0201669.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Transmission-blocking activity of antibodies to Plasmodium falciparum GLURP.10C chimeric protein formulated in different adjuvants

    Roeffen, W., Theisen, Michael, van de Vegte-Bolmer, M., van Gemert, G., Arens, T., Andersen, G., Christiansen, M., Sevargave, L., Singh, S. K., Kaviraj, S. & Sauerwein, R., 2015, In: Malaria Journal. 14, 9 p., 443.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Assessing malaria transmission in a low endemicity area of north-western Peru

    Rosas-Aguirre, A., Llanos-Cuentas, A., Speybroeck, N., Cook, J., Contreras-Mancilla, J., Soto, V., Gamboa, D., Pozo, E., Ponce, O. J., Pereira, M. O., Soares, I. S., Theisen, Michael, D'Alessandro, U. & Erhart, A., 2013, In: Malaria Journal. 12, 1, p. 339

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    40 Years of Pfs48/45 Research as a Transmission-Blocking Vaccine Target of Plasmodium falciparum Malaria

    Sauerwein, R. W., Plieskatt, J. & Theisen, Michael, 2022, In: American Journal of Tropical Medicine and Hygiene. 107, p. 22-26 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Molecular and functional characterization of Fcγ receptor IIIb-ligand interaction: Implications for neutrophil-mediated immune mechanisms in malaria

    Simtong, P., Romphruk, A. V., Traum, A., Burg-Roderfeld, M., Bein, G., Jakubowski, K., Dominik, A., Theisen, Michael, Kana, Ikhlaq Hussain, Sachs, U. J. & Santoso, S., 2018, In: Infection and Immunity. 86, 8, e00924-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A reproducible and scalable process for manufacturing a Pfs48/45 based Plasmodium falciparum transmission-blocking vaccine

    Singh, S. K., Plieskatt, J., Chourasia, B. K., Fabra-García, A., Garcia-Senosiain, A., Singh, V., Bengtsson, K. L., Reimer, J. M., Sauerwein, R., Jore, M. M. & Theisen, Michael, 2021, In: Frontiers in Immunology. 11, 606266.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Improving the malaria transmission-blocking activity of a Plasmodium falciparum 48/45 based vaccine antigen by SpyTag/SpyCatcher mediated virus-like display

    Singh, S. K., Thrane, Susan, Janitzek, C. M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Theisen, Michael, Salanti, Ali & Sander, Adam F. , 2017, In: Vaccine. 35, 30, p. 3726-3732 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The Plasmodium falciparum circumsporozoite protein produced in Lactococcus lactis is pure and stable

    Singh, S. K., Plieskatt, J., Chourasia, B. K., Singh, V., Bolscher, J. M., Dechering, K. J., Adu, B., López-Méndez, B., Kaviraj, S., Locke, E., King, C. R. & Theisen, Michael, 2020, In: Journal of Biological Chemistry. 295, 2, p. 403-414 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Preclinical development of a Pfs230-Pfs48/45 chimeric malaria transmission-blocking vaccine

    Singh, S. K., Plieskatt, J., Chourasia, B. K., Singh, V., Bengtsson, K. L., Reimer, J. M., van Daalen, R. C., Teelen, K., van de Vegte-Bolmer, M., van Gemert, G., Jore, M. M. & Theisen, Michael, 2021, In: npj Vaccines. 6, 11 p., 120.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    A Plasmodium falciparum 48/45 single epitope R0.6C subunit protein elicits high levels of transmission blocking antibodies

    Singh, S. K., Roeffen, W., Andersen, G., Bousema, T., Christiansen, M., Sauerwein, R. & Theisen, Michael, 15 Apr 2015, In: Vaccine. 33, 16, p. 1981-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Pfs230 and Pfs48/45 fusion proteins elicit strong transmission-blocking antibody responses against Plasmodium falciparum

    Singh, S. K., Thrane, Susan, Chourasia, B. K., Teelen, K., Graumans, W., Stoter, R., van Gemert, G., van de Vegte-Bolmer, M. G., Nielsen, Morten Agertoug, Salanti, Ali, Sander, Adam F. , Sauerwein, R. W., Jore, M. M. & Theisen, Michael, 2019, In: Frontiers in Immunology. 10, 1256.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Lactococcus lactis provides an efficient platform for production of disulfide-rich recombinant proteins from Plasmodium falciparum

    Singh, S. K., Tiendrebeogo, R. W., Chourasia, B. K., Kana, Ikhlaq Hussain, Singh, S. & Theisen, Michael, 2018, In: Microbial Cell Factories. 17, 13 p., 55.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Construct design, production, and characterization of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine

    Singh, S. K., Roeffen, W., Mistarz, U. H., Chourasia, B. K., Yang, F., Rand, Kasper Dyrberg, Sauerwein, R. W. & Theisen, Michael, 2017, In: Microbial Cell Factories. 16, 1, 11 p., 97.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Cloning and recombinant protein expression in Lactococcus lactis

    Singh, S. K., Naghizadeh, Mohammad, Plieskatt, J., Singh, S. & Theisen, Michael, 2023, Advanced Methods in Structural Biology. Sousa, Â. & Passarinha, L. (eds.). Humana Press, p. 3-20 18 p. (Methods in Molecular Biology, Vol. 2652).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  22. Published

    A phase 2b randomized, controlled trial of the efficacy of the GMZ2 malaria vaccine in African children

    Sirima, S. B., Mordmüller, B., Milligan, P., Ngoa, U. A., Kironde, F., Atuguba, F., Tiono, A. B., Issifou, S., Kaddumukasa, M., Bangre, O., Flach, C., Christiansen, M., Bang, P., Chilengi, R., Jepsen, S., Kremsner, P. G. & Theisen, Michael, Aug 2016, In: Vaccine. 34, 38, p. 4536-4542 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The candidate blood-stage malaria vaccine P27A induces a robust humoral response in a fast track to the field Phase 1 trial in exposed and nonexposed volunteers

    Steiner-Monard, V., Kamaka, K., Karoui, O., Roethlisberger, S., Audran, R., Daubenberger, C., Fayet-Mello, A., Erdmann-Voisin, A., Felger, I., Geiger, K., Govender, L., Houard, S., Huber, E., Mayor, C., Mkindi, C., Portevin, D., Rusch, S., Schmidlin, S., Tiendrebeogo, R. W., Theisen, M. & 9 others, Thierry, A., Vallotton, L., Corradin, G., Leroy, O., Abdulla, S., Shekalaghe, S., Genton, B., Spertini, F. & Jongo, S. A., 2019, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 68, 3, p. 466-474 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity

    Stone, W. J. R., Campo, J. J., Ouédraogo, A. L., Meerstein-Kessel, L., Morlais, I., Da, D., Cohuet, A., Nsango, S., Sutherland, C. J., van de Vegte-Bolmer, M., Siebelink-Stoter, R., van Gemert, G-J., Graumans, W., Lanke, K., Shandling, A. D., Pablo, J. V., Teng, A. A., Jones, S., de Jong, R. M., Fabra-García, A. & 14 others, Bradley, J., Roeffen, W., Lasonder, E., Gremo, G., Schwarzer, E., Janse, C. J., Singh, S. K., Theisen, Michael, Felgner, P., Marti, M., Drakeley, C., Sauerwein, R., Bousema, T. & Jore, M. M., 8 Feb 2018, In: Nature Communications. 9, 1, 14 p., 558.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Immunogenicity of a virosomally-formulated Plasmodium falciparum GLURP-MSP3 chimeric protein-based malaria vaccine candidate in comparison to adjuvanted formulations

    Tamborrini, M., Stoffel, S. A., Westerfeld, N., Amacker, M., Theisen, Michael, Zurbriggen, R. & Pluschke, G., 2011, In: Malaria Journal. 10, p. 359

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 10528769