Structure-activity studies: in vitro antileishmanial and antimalarial activities of anthraquinones from Morinda lucida
Research output: Contribution to journal › Journal article › Research › peer-review
Anthraquinones have been isolated by bioassay-guided fractionation from Morinda lucida. Structure-activity studies show that an aldehyde group at C-2 and a phenolic hydroxy group at C-3 enhance the activity of the anthraquinones against the growth of Plasmodium falciparum and promastigotes of Leishmania major in vitro.
| Original language | English |
|---|---|
| Journal | Planta Medica |
| Volume | 65 |
| Issue number | 3 |
| Pages (from-to) | 259-61 |
| Number of pages | 2 |
| ISSN | 0032-0943 |
| Publication status | Published - 1999 |
Bibliographical note
Keywords: Animals; Anthraquinones; Antimalarials; Antiprotozoal Agents; Leishmania major; Plasmodium falciparum; Rubiaceae; Structure-Activity Relationship
ID: 6748028