Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites. / Bejon, Philip; Turner, Louise; Lavstsen, Thomas; Cham, Gerald; Olotu, Ally; Drakeley, Chris J; Lievens, Marc; Vekemans, Johan; Savarese, Barbara; Lusingu, John; von Seidlein, Lorenz; Bull, Peter C; Marsh, Kevin; Theander, Thor G.

In: P L o S One, Vol. 6, No. 6, 01.01.2011, p. e21711.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Bejon, P, Turner, L, Lavstsen, T, Cham, G, Olotu, A, Drakeley, CJ, Lievens, M, Vekemans, J, Savarese, B, Lusingu, J, von Seidlein, L, Bull, PC, Marsh, K & Theander, TG 2011, 'Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites', P L o S One, vol. 6, no. 6, pp. e21711. https://doi.org/10.1371/journal.pone.0021711

APA

Bejon, P., Turner, L., Lavstsen, T., Cham, G., Olotu, A., Drakeley, C. J., Lievens, M., Vekemans, J., Savarese, B., Lusingu, J., von Seidlein, L., Bull, P. C., Marsh, K., & Theander, T. G. (2011). Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites. P L o S One, 6(6), e21711. https://doi.org/10.1371/journal.pone.0021711

Vancouver

Bejon P, Turner L, Lavstsen T, Cham G, Olotu A, Drakeley CJ et al. Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites. P L o S One. 2011 Jan 1;6(6):e21711. https://doi.org/10.1371/journal.pone.0021711

Author

Bejon, Philip ; Turner, Louise ; Lavstsen, Thomas ; Cham, Gerald ; Olotu, Ally ; Drakeley, Chris J ; Lievens, Marc ; Vekemans, Johan ; Savarese, Barbara ; Lusingu, John ; von Seidlein, Lorenz ; Bull, Peter C ; Marsh, Kevin ; Theander, Thor G. / Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites. In: P L o S One. 2011 ; Vol. 6, No. 6. pp. e21711.

Bibtex

@article{0b0031d0432845848b092eea88ca6b94,
title = "Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites",
abstract = "Malaria transmission may be considered to be homogenous with well-mixed parasite populations (as in the classic Ross/Macdonald models). Marked fine-scale heterogeneity of transmission has been observed in the field (i.e., over a few kilometres), but there are relatively few data on the degree of mixing. Since the Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) is highly polymorphic, the host's serological responses may be used to infer exposure to parasite sub-populations.",
keywords = "Aging, Animals, Antibody Formation, Cluster Analysis, Humans, Infant, Malaria, Plasmodium falciparum, Principal Component Analysis, Protozoan Proteins, Serologic Tests, Time Factors",
author = "Philip Bejon and Louise Turner and Thomas Lavstsen and Gerald Cham and Ally Olotu and Drakeley, {Chris J} and Marc Lievens and Johan Vekemans and Barbara Savarese and John Lusingu and {von Seidlein}, Lorenz and Bull, {Peter C} and Kevin Marsh and Theander, {Thor G}",
year = "2011",
month = jan,
day = "1",
doi = "10.1371/journal.pone.0021711",
language = "English",
volume = "6",
pages = "e21711",
journal = "PLoS ONE",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "6",

}

RIS

TY - JOUR

T1 - Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites

AU - Bejon, Philip

AU - Turner, Louise

AU - Lavstsen, Thomas

AU - Cham, Gerald

AU - Olotu, Ally

AU - Drakeley, Chris J

AU - Lievens, Marc

AU - Vekemans, Johan

AU - Savarese, Barbara

AU - Lusingu, John

AU - von Seidlein, Lorenz

AU - Bull, Peter C

AU - Marsh, Kevin

AU - Theander, Thor G

PY - 2011/1/1

Y1 - 2011/1/1

N2 - Malaria transmission may be considered to be homogenous with well-mixed parasite populations (as in the classic Ross/Macdonald models). Marked fine-scale heterogeneity of transmission has been observed in the field (i.e., over a few kilometres), but there are relatively few data on the degree of mixing. Since the Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) is highly polymorphic, the host's serological responses may be used to infer exposure to parasite sub-populations.

AB - Malaria transmission may be considered to be homogenous with well-mixed parasite populations (as in the classic Ross/Macdonald models). Marked fine-scale heterogeneity of transmission has been observed in the field (i.e., over a few kilometres), but there are relatively few data on the degree of mixing. Since the Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) is highly polymorphic, the host's serological responses may be used to infer exposure to parasite sub-populations.

KW - Aging

KW - Animals

KW - Antibody Formation

KW - Cluster Analysis

KW - Humans

KW - Infant

KW - Malaria

KW - Plasmodium falciparum

KW - Principal Component Analysis

KW - Protozoan Proteins

KW - Serologic Tests

KW - Time Factors

U2 - 10.1371/journal.pone.0021711

DO - 10.1371/journal.pone.0021711

M3 - Journal article

C2 - 21747921

VL - 6

SP - e21711

JO - PLoS ONE

JF - PLoS ONE

SN - 1932-6203

IS - 6

ER -

ID: 35277228