Plasmodium falciparum parasites expressing pregnancy-specific variant surface antigens adhere strongly to the choriocarcinoma cell line BeWo

Research output: Contribution to journal › Journal article › Research › peer-review

  • Rikke N Haase
  • Rosette Megnekou
  • Maja Lundquist
  • Michael F Ofori
  • Hviid, Lars
  • Trine Staalsoe
Placenta-sequestering Plasmodium falciparum parasites causing pregnancy-associated malaria express pregnancy-specific variant surface antigens (VSA(PAM)). We report here that VSA(PAM)-expressing patient isolates adhere strongly to the choriocarcinoma cell line BeWo and that the BeWo line can be used to efficiently select for VSA(PAM) expression in vitro.
Original languageEnglish
JournalInfection and Immunity
Volume74
Issue number5
Pages (from-to)3035-8
Number of pages3
ISSN0019-9567
DOIs
Publication statusPublished - 2006

Bibliographical note

Keywords: Animals; Antigens, Protozoan; CHO Cells; Cell Line, Tumor; Choriocarcinoma; Cricetinae; Erythrocytes; Female; Humans; Malaria, Falciparum; Placenta; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic; Uterine Neoplasms

ID: 6746833