Etiology of placental Plasmodium falciparum malaria in African women

Research output: Contribution to journal › Journal article › Research › peer-review

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Etiology of placental Plasmodium falciparum malaria in African women. / Ofori, Michael F; Lamptey, Helena; Dickson, Emmanuel K; Kyei-Baafour, Eric; Hviid, Lars.

In: The Journal of Infectious Diseases, Vol. 218, No. 2, 2018, p. 277-281.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Ofori, MF, Lamptey, H, Dickson, EK, Kyei-Baafour, E & Hviid, L 2018, 'Etiology of placental Plasmodium falciparum malaria in African women', The Journal of Infectious Diseases, vol. 218, no. 2, pp. 277-281. https://doi.org/10.1093/infdis/jiy168

APA

Ofori, M. F., Lamptey, H., Dickson, E. K., Kyei-Baafour, E., & Hviid, L. (2018). Etiology of placental Plasmodium falciparum malaria in African women. The Journal of Infectious Diseases, 218(2), 277-281. https://doi.org/10.1093/infdis/jiy168

Vancouver

Ofori MF, Lamptey H, Dickson EK, Kyei-Baafour E, Hviid L. Etiology of placental Plasmodium falciparum malaria in African women. The Journal of Infectious Diseases. 2018;218(2):277-281. https://doi.org/10.1093/infdis/jiy168

Author

Ofori, Michael F ; Lamptey, Helena ; Dickson, Emmanuel K ; Kyei-Baafour, Eric ; Hviid, Lars. / Etiology of placental Plasmodium falciparum malaria in African women. In: The Journal of Infectious Diseases. 2018 ; Vol. 218, No. 2. pp. 277-281.

Bibtex

@article{7005b2f4d2c944329b2c9b8b5c0f8ed7,
title = "Etiology of placental Plasmodium falciparum malaria in African women",
abstract = "Plasmodium falciparum parasites causing placental malaria express the VAR2CSA type of the clonally variant antigen family erythrocyte membrane protein 1 (PfEMP1). This enables evasion of preexisting immunity and results in placental accumulation of infected erythrocytes. We present data on seasonal variation in levels of VAR2CSA-specific immunoglobulin G (IgG) and IgG specific for a placental malaria-unrelated PfEMP1 protein among Ghanaian women at their first antenatal visit. Our results indicate that placental malaria does not require recent exposure to infected mosquitoes, in contrast to malaria in general. This has implications for the impact of insecticide-treated bed nets on placental malaria incidence and for antenatal care in woman with preexisting immunity.",
author = "Ofori, {Michael F} and Helena Lamptey and Dickson, {Emmanuel K} and Eric Kyei-Baafour and Lars Hviid",
year = "2018",
doi = "10.1093/infdis/jiy168",
language = "English",
volume = "218",
pages = "277--281",
journal = "Journal of Infectious Diseases",
issn = "0022-1899",
publisher = "Oxford University Press",
number = "2",

}

RIS

TY - JOUR

T1 - Etiology of placental Plasmodium falciparum malaria in African women

AU - Ofori, Michael F

AU - Lamptey, Helena

AU - Dickson, Emmanuel K

AU - Kyei-Baafour, Eric

AU - Hviid, Lars

PY - 2018

Y1 - 2018

N2 - Plasmodium falciparum parasites causing placental malaria express the VAR2CSA type of the clonally variant antigen family erythrocyte membrane protein 1 (PfEMP1). This enables evasion of preexisting immunity and results in placental accumulation of infected erythrocytes. We present data on seasonal variation in levels of VAR2CSA-specific immunoglobulin G (IgG) and IgG specific for a placental malaria-unrelated PfEMP1 protein among Ghanaian women at their first antenatal visit. Our results indicate that placental malaria does not require recent exposure to infected mosquitoes, in contrast to malaria in general. This has implications for the impact of insecticide-treated bed nets on placental malaria incidence and for antenatal care in woman with preexisting immunity.

AB - Plasmodium falciparum parasites causing placental malaria express the VAR2CSA type of the clonally variant antigen family erythrocyte membrane protein 1 (PfEMP1). This enables evasion of preexisting immunity and results in placental accumulation of infected erythrocytes. We present data on seasonal variation in levels of VAR2CSA-specific immunoglobulin G (IgG) and IgG specific for a placental malaria-unrelated PfEMP1 protein among Ghanaian women at their first antenatal visit. Our results indicate that placental malaria does not require recent exposure to infected mosquitoes, in contrast to malaria in general. This has implications for the impact of insecticide-treated bed nets on placental malaria incidence and for antenatal care in woman with preexisting immunity.

U2 - 10.1093/infdis/jiy168

DO - 10.1093/infdis/jiy168

M3 - Journal article

C2 - 29579263

VL - 218

SP - 277

EP - 281

JO - Journal of Infectious Diseases

JF - Journal of Infectious Diseases

SN - 0022-1899

IS - 2

ER -

ID: 198575148