Determination of beta-defensin genomic copy number in different populations: a comparison of three methods

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Determination of beta-defensin genomic copy number in different populations : a comparison of three methods. / Fode, Peder; Jespersgaard, Cathrine; Hardwick, Robert J; Bogle, Helen; Theisen, Michael; Dodoo, Daniel; Lenicek, Martin; Vitek, Libor; Vieira, Ana; Freitas, Joao; Andersen, Paal Skytt; Hollox, Edward J.

In: P L o S One, Vol. 6, No. 2, 2011, p. e16768.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Fode, P, Jespersgaard, C, Hardwick, RJ, Bogle, H, Theisen, M, Dodoo, D, Lenicek, M, Vitek, L, Vieira, A, Freitas, J, Andersen, PS & Hollox, EJ 2011, 'Determination of beta-defensin genomic copy number in different populations: a comparison of three methods', P L o S One, vol. 6, no. 2, pp. e16768. https://doi.org/10.1371/journal.pone.0016768

APA

Fode, P., Jespersgaard, C., Hardwick, R. J., Bogle, H., Theisen, M., Dodoo, D., Lenicek, M., Vitek, L., Vieira, A., Freitas, J., Andersen, P. S., & Hollox, E. J. (2011). Determination of beta-defensin genomic copy number in different populations: a comparison of three methods. P L o S One, 6(2), e16768. https://doi.org/10.1371/journal.pone.0016768

Vancouver

Fode P, Jespersgaard C, Hardwick RJ, Bogle H, Theisen M, Dodoo D et al. Determination of beta-defensin genomic copy number in different populations: a comparison of three methods. P L o S One. 2011;6(2):e16768. https://doi.org/10.1371/journal.pone.0016768

Author

Fode, Peder ; Jespersgaard, Cathrine ; Hardwick, Robert J ; Bogle, Helen ; Theisen, Michael ; Dodoo, Daniel ; Lenicek, Martin ; Vitek, Libor ; Vieira, Ana ; Freitas, Joao ; Andersen, Paal Skytt ; Hollox, Edward J. / Determination of beta-defensin genomic copy number in different populations : a comparison of three methods. In: P L o S One. 2011 ; Vol. 6, No. 2. pp. e16768.

Bibtex

@article{6bde710e18214c2eaf6e8a16bf552732,
title = "Determination of beta-defensin genomic copy number in different populations: a comparison of three methods",
abstract = "There have been conflicting reports in the literature on association of gene copy number with disease, including CCL3L1 and HIV susceptibility, and {\ss}-defensins and Crohn's disease. Quantification of precise gene copy numbers is important in order to define any association of gene copy number with disease. At present, real-time quantitative PCR (QPCR) is the most commonly used method to determine gene copy number, however the Paralogue Ratio Test (PRT) is being used in more and more laboratories.",
keywords = "Base Sequence, Chromosome Mapping, Cohort Studies, Czech Republic, Denmark, Gene Dosage, Genetic Predisposition to Disease, Genetics, Population, Genome, Human, Ghana, Great Britain, Humans, Molecular Sequence Data, Population, Portugal, beta-Defensins",
author = "Peder Fode and Cathrine Jespersgaard and Hardwick, {Robert J} and Helen Bogle and Michael Theisen and Daniel Dodoo and Martin Lenicek and Libor Vitek and Ana Vieira and Joao Freitas and Andersen, {Paal Skytt} and Hollox, {Edward J}",
year = "2011",
doi = "10.1371/journal.pone.0016768",
language = "English",
volume = "6",
pages = "e16768",
journal = "PLoS ONE",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "2",

}

RIS

TY - JOUR

T1 - Determination of beta-defensin genomic copy number in different populations

T2 - a comparison of three methods

AU - Fode, Peder

AU - Jespersgaard, Cathrine

AU - Hardwick, Robert J

AU - Bogle, Helen

AU - Theisen, Michael

AU - Dodoo, Daniel

AU - Lenicek, Martin

AU - Vitek, Libor

AU - Vieira, Ana

AU - Freitas, Joao

AU - Andersen, Paal Skytt

AU - Hollox, Edward J

PY - 2011

Y1 - 2011

N2 - There have been conflicting reports in the literature on association of gene copy number with disease, including CCL3L1 and HIV susceptibility, and ß-defensins and Crohn's disease. Quantification of precise gene copy numbers is important in order to define any association of gene copy number with disease. At present, real-time quantitative PCR (QPCR) is the most commonly used method to determine gene copy number, however the Paralogue Ratio Test (PRT) is being used in more and more laboratories.

AB - There have been conflicting reports in the literature on association of gene copy number with disease, including CCL3L1 and HIV susceptibility, and ß-defensins and Crohn's disease. Quantification of precise gene copy numbers is important in order to define any association of gene copy number with disease. At present, real-time quantitative PCR (QPCR) is the most commonly used method to determine gene copy number, however the Paralogue Ratio Test (PRT) is being used in more and more laboratories.

KW - Base Sequence

KW - Chromosome Mapping

KW - Cohort Studies

KW - Czech Republic

KW - Denmark

KW - Gene Dosage

KW - Genetic Predisposition to Disease

KW - Genetics, Population

KW - Genome, Human

KW - Ghana

KW - Great Britain

KW - Humans

KW - Molecular Sequence Data

KW - Population

KW - Portugal

KW - beta-Defensins

U2 - 10.1371/journal.pone.0016768

DO - 10.1371/journal.pone.0016768

M3 - Journal article

C2 - 21364933

VL - 6

SP - e16768

JO - PLoS ONE

JF - PLoS ONE

SN - 1932-6203

IS - 2

ER -

ID: 40245792