Absence of Pneumocystis jirovecii colonization in human immunodeficiency virus-infected individuals with and without airway obstruction and with undetectable viral load

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Absence of Pneumocystis jirovecii colonization in human immunodeficiency virus-infected individuals with and without airway obstruction and with undetectable viral load. / Ronit, Andreas; Klitbo, Ditte Marie; Kildemoes, Anna Overgaard; Benfield, Thomas; Gerstoft, Jan; Vestbo, Jørgen; Jensen, Jørgen Skov; Kurtzhals, Jørgen; Nielsen, Susanne Dam.

In: Open forum in Infectious Diseases, Vol. 3, No. 1, ofw044, 2016.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Ronit, A, Klitbo, DM, Kildemoes, AO, Benfield, T, Gerstoft, J, Vestbo, J, Jensen, JS, Kurtzhals, J & Nielsen, SD 2016, 'Absence of Pneumocystis jirovecii colonization in human immunodeficiency virus-infected individuals with and without airway obstruction and with undetectable viral load', Open forum in Infectious Diseases, vol. 3, no. 1, ofw044. https://doi.org/10.1093/ofid/ofw044

APA

Ronit, A., Klitbo, D. M., Kildemoes, A. O., Benfield, T., Gerstoft, J., Vestbo, J., Jensen, J. S., Kurtzhals, J., & Nielsen, S. D. (2016). Absence of Pneumocystis jirovecii colonization in human immunodeficiency virus-infected individuals with and without airway obstruction and with undetectable viral load. Open forum in Infectious Diseases, 3(1), [ofw044]. https://doi.org/10.1093/ofid/ofw044

Vancouver

Ronit A, Klitbo DM, Kildemoes AO, Benfield T, Gerstoft J, Vestbo J et al. Absence of Pneumocystis jirovecii colonization in human immunodeficiency virus-infected individuals with and without airway obstruction and with undetectable viral load. Open forum in Infectious Diseases. 2016;3(1). ofw044. https://doi.org/10.1093/ofid/ofw044

Author

Ronit, Andreas ; Klitbo, Ditte Marie ; Kildemoes, Anna Overgaard ; Benfield, Thomas ; Gerstoft, Jan ; Vestbo, Jørgen ; Jensen, Jørgen Skov ; Kurtzhals, Jørgen ; Nielsen, Susanne Dam. / Absence of Pneumocystis jirovecii colonization in human immunodeficiency virus-infected individuals with and without airway obstruction and with undetectable viral load. In: Open forum in Infectious Diseases. 2016 ; Vol. 3, No. 1.

Bibtex

@article{d3c51b738a6a42f3bcca21a4f4a6e5d7,
title = "Absence of Pneumocystis jirovecii colonization in human immunodeficiency virus-infected individuals with and without airway obstruction and with undetectable viral load",
abstract = "Pneumocystis jirovecii colonization has been associated with non-acquired immune deficiency syndrome (AIDS) pulmonary comorbidity. We used spirometry to measure pulmonary function and analyzed oral wash specimens by quantitative polymerase chain reaction (PCR), targeting the large mitochondrial ribosomal subunit. For sensitivity control, a blinded subsample was subjected to touch-down PCRs, targeting both large and small ribosomal subunits and the major surface glycoprotein. Pneumocystis jirovecii deoxyribonucleic acid (DNA) was detected in 1 of 156 (95% confidence interval, .1%-3.5%) virologically suppressed human immunodeficiency virus (HIV)-infected individuals confirmed by all PCR methods. Thus, prevalence of P jirovecii colonization was low and unlikely to be a major cause of pulmonary comorbidity in this group of well treated HIV-infected individuals.",
author = "Andreas Ronit and Klitbo, {Ditte Marie} and Kildemoes, {Anna Overgaard} and Thomas Benfield and Jan Gerstoft and J{\o}rgen Vestbo and Jensen, {J{\o}rgen Skov} and J{\o}rgen Kurtzhals and Nielsen, {Susanne Dam}",
year = "2016",
doi = "10.1093/ofid/ofw044",
language = "English",
volume = "3",
journal = "Open Forum Infectious Diseases",
issn = "2328-8957",
publisher = "Oxford University Press",
number = "1",

}

RIS

TY - JOUR

T1 - Absence of Pneumocystis jirovecii colonization in human immunodeficiency virus-infected individuals with and without airway obstruction and with undetectable viral load

AU - Ronit, Andreas

AU - Klitbo, Ditte Marie

AU - Kildemoes, Anna Overgaard

AU - Benfield, Thomas

AU - Gerstoft, Jan

AU - Vestbo, Jørgen

AU - Jensen, Jørgen Skov

AU - Kurtzhals, Jørgen

AU - Nielsen, Susanne Dam

PY - 2016

Y1 - 2016

N2 - Pneumocystis jirovecii colonization has been associated with non-acquired immune deficiency syndrome (AIDS) pulmonary comorbidity. We used spirometry to measure pulmonary function and analyzed oral wash specimens by quantitative polymerase chain reaction (PCR), targeting the large mitochondrial ribosomal subunit. For sensitivity control, a blinded subsample was subjected to touch-down PCRs, targeting both large and small ribosomal subunits and the major surface glycoprotein. Pneumocystis jirovecii deoxyribonucleic acid (DNA) was detected in 1 of 156 (95% confidence interval, .1%-3.5%) virologically suppressed human immunodeficiency virus (HIV)-infected individuals confirmed by all PCR methods. Thus, prevalence of P jirovecii colonization was low and unlikely to be a major cause of pulmonary comorbidity in this group of well treated HIV-infected individuals.

AB - Pneumocystis jirovecii colonization has been associated with non-acquired immune deficiency syndrome (AIDS) pulmonary comorbidity. We used spirometry to measure pulmonary function and analyzed oral wash specimens by quantitative polymerase chain reaction (PCR), targeting the large mitochondrial ribosomal subunit. For sensitivity control, a blinded subsample was subjected to touch-down PCRs, targeting both large and small ribosomal subunits and the major surface glycoprotein. Pneumocystis jirovecii deoxyribonucleic acid (DNA) was detected in 1 of 156 (95% confidence interval, .1%-3.5%) virologically suppressed human immunodeficiency virus (HIV)-infected individuals confirmed by all PCR methods. Thus, prevalence of P jirovecii colonization was low and unlikely to be a major cause of pulmonary comorbidity in this group of well treated HIV-infected individuals.

U2 - 10.1093/ofid/ofw044

DO - 10.1093/ofid/ofw044

M3 - Journal article

C2 - 27006967

VL - 3

JO - Open Forum Infectious Diseases

JF - Open Forum Infectious Diseases

SN - 2328-8957

IS - 1

M1 - ofw044

ER -

ID: 159239901