GLURP team

  1. 2021
  2. Published

    Exploratory analysis of the effect of helminth infection on the immunogenicity and efficacy of the asexual blood-stage malaria vaccine candidate GMZ2

    Nouatin, O., Mengue, J. B., Dejon-Agobé, J. C., Fendel, R., Ibáñez, J., Ngoa, U. A., Edoa, J. R., Adégbité, B. R., Honkpéhédji, Y. J., Zinsou, J. F., Hounkpatin, A. B., Moutairou, K., Homoet, A., Esen, M., Kreidenweiss, A., Hoffman, S. L., Theisen, M., Luty, A. J. F., Lell, B., Agnandji, S. T. & 5 others, Mombo-Ngoma, G., Ramharter, M., Kremsner, P., Mordmüller, B. & Adegnika, A. A., 2021, In: PLoS Neglected Tropical Diseases. 15, 6, 18 p., e0009361.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Extended follow-up of children in a phase2b trial of the GMZ2 malaria vaccine

    Dassah, S., Adu, B., Sirima, S. B., Mordmüller, B., Ngoa, U. A., Atuguba, F., Arthur, F. K. N., Mensah, B. A., Kaddumukasa, M., Bang, P., Kremsner, P. G., Mategula, D., Flach, C., Milligan, P. & Theisen, Michael, 2021, In: Vaccine. 39, 31, p. 4314-4319 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Identification of single-nucleotide polymorphisms in the mitochondrial genome and kelch 13 gene of Plasmodium falciparum in different geographical populations

    Nydahl, T. K., Ahorhorlu, S. Y., Ndiaye, M., Das, M. K., Hansson, Helle Smedegaard, Crespo Bravo, Marina, Wang, Christian William, Lusingu, J., Theisen, Michael, Singh, S. K., Singh, S., Campino, S., Lund, O., Roper, C. & Alifrangis, Michael, 2021, In: American Journal of Tropical Medicine and Hygiene. 105, 4, p. 1085-1092 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Neutrophils dominate in opsonic phagocytosis of P. falciparum blood-stage merozoites and protect against febrile malaria

    Garcia-Senosiain, A., Kana, Ikhlaq Hussain, Singh, S., Das, M. K., Dziegiel, Morten Hanefeld, Hertegonne, S., Adu, B. & Theisen, Michael, 2021, In: Communications Biology . 4, 984.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Preclinical development of a Pfs230-Pfs48/45 chimeric malaria transmission-blocking vaccine

    Singh, S. K., Plieskatt, J., Chourasia, B. K., Singh, V., Bengtsson, K. L., Reimer, J. M., van Daalen, R. C., Teelen, K., van de Vegte-Bolmer, M., van Gemert, G., Jore, M. M. & Theisen, Michael, 2021, In: npj Vaccines. 6, 11 p., 120.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Suitability of IgG responses to multiple Plasmodium falciparum antigens as markers of transmission intensity and pattern

    Kyei-Baafour, E., Oppong, M., Kusi, K. A., Frempong, A. F., Aculley, B., Arthur, F. K. N., Tiendrebeogo, R. W., Singh, S. K., Theisen, Michael, Kweku, M., Adu, B., Hviid, Lars & Ofori, M. F., 2021, In: PLoS ONE. 16, 4, e0249936.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2020
  9. Published

    Effect of immune regulatory pathways after immunization with GMZ2 malaria vaccine candidate in healthy lifelong malaria-exposed adults

    Nouatin, O., Ateba Ngoa, U., Ibáñez, J., Dejon-Agobe, J. C., Mordmüller, B., Edoa, J. R., Mougeni, F., Brückner, S., Bouyoukou Hounkpatin, A., Esen, M., Theisen, Michael, Moutairou, K., Hoffman, S. L., Issifou, S., Luty, A. J. F., Loembe, M. M., Agnandji, S. T., Lell, B., Kremsner, P. G. & Adegnika, A. A., 2 Jun 2020, In: Vaccine. 38, 27, p. 4263-4272 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Plasmodium falciparum Clag9-associated PfRhopH complex is involved in merozoite binding to human erythrocytes

    Chourasia, B. K., Deshmukh, A., Kaur, I., Paul, G., Panda, A., Rathore, S., Singh, S. K., Theisen, Michael, Mohmmed, A. & Malhotra, P., 2020, In: Infection and Immunity. 88, 2, e00504-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Antibody responses to a suite of novel serological markers for malaria surveillance demonstrate strong correlation with clinical and parasitological infection across seasons and transmission settings in The Gambia

    Wu, L., Mwesigwa, J., Affara, M., Bah, M., Correa, S., Hall, T., Singh, S. K., Beeson, J. G., Tetteh, K. K. A., Kleinschmidt, I., D'Alessandro, U. & Drakeley, C., 2020, In: BMC Medicine. 18, 1, 304.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Comparison of Commercial ELISA Kits to Confirm the Absence of Transmission in Malaria Elimination Settings

    van den Hoogen, L. L., Bareng, P., Alves, J., Reyes, R., Macalinao, M., Rodrigues, J. M., Fernandes, J. M., Goméz, L. F., Hall, T., Singh, S. K., Fornace, K., Luchavez, J., Kitchen, A., Chiodini, P., Espino, F., Tetteh, K. K. A., Stresman, G., Sepúlveda, N. & Drakeley, C., 2020, In: Frontiers in Public Health. 8, 480.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Evaluating the predictive performance of malaria antibodies and FCGR3B gene polymorphisms on Plasmodium falciparum infection outcome: a prospective cohort study

    Dwomoh, D., Adu, B., Dodoo, D., Theisen, Michael, Iddi, S. & Gerds, Thomas Alexander, 2020, In: Malaria Journal. 19, 1, 12 p., 307.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Microscopic and submicroscopic asymptomatic Plasmodium falciparum infections in Ghanaian children and protection against febrile malaria

    Adu, B., Issahaque, Q., Sarkodie-Addo, T., Kumordjie, S., Kyei-Baafour, E., Sinclear, C. K., Eyia-Ampah, S., Owusu-Yeboa, E., Theisen, Michael & Dodoo, D., 2020, In: Infection and Immunity. 88, 10, e00125-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Peripheral Merozoite Surface Proteins Are Targets of Naturally Acquired Immunity against Malaria in both India and Ghana

    Garcia-Senosiain, A., Kana, Ikhlaq Hussain, Singh, S. K., Chourasia, B. K., Das, M. K., Dodoo, D., Singh, S., Adu, B. & Theisen, Michael, 2020, In: Infection and Immunity. 88, 4, e00778-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Selection of antibody responses associated with Plasmodium falciparum infections in the context of malaria elimination

    van den Hoogen, L. L., Stresman, G., Présumé, J., Romilus, I., Mondélus, G., Elismé, T., Existe, A., Hamre, K. E. S., Ashton, R. A., Druetz, T., Joseph, V., Beeson, J. G., Singh, S. K., Boncy, J., Eisele, T. P., Chang, M. A., Lemoine, J. F., Tetteh, K. K. A., Rogier, E. & Drakeley, C., 2020, In: Frontiers in Immunology. 11, 12 p., 928.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Sero-epidemiological evaluation of malaria transmission in The Gambia before and after mass drug administration

    Wu, L., Mwesigwa, J., Affara, M., Bah, M., Correa, S., Hall, T., Singh, S. K., Beeson, J. G., Tetteh, K. K. A., Kleinschmidt, I., D’Alessandro, U. & Drakeley, C., 2020, In: BMC Medicine. 18, 331.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Stage-specific Plasmodium falciparum immune responses in afebrile adults and children living in the Greater Accra Region of Ghana

    Acquah, F. K., Lo, A. C., Akyea-Mensah, K., Abagna, H. B., Faye, B., Theisen, Michael, Gyan, B. A. & Amoah, L. E., 2020, In: Malaria Journal. 19, 1, 11 p., 64.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The Plasmodium falciparum circumsporozoite protein produced in Lactococcus lactis is pure and stable

    Singh, S. K., Plieskatt, J., Chourasia, B. K., Singh, V., Bolscher, J. M., Dechering, K. J., Adu, B., López-Méndez, B., Kaviraj, S., Locke, E., King, C. R. & Theisen, Michael, 2020, In: Journal of Biological Chemistry. 295, 2, p. 403-414 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2019
  21. Published

    Plasmodium falciparum merozoite surface antigen-specific cytophilic IgG and control of malaria infection in a Beninese birth cohort

    Adamou, R., Dechavanne, C., Sadissou, I., d'Almeida, T., Bouraima, A., Sonon, P., Amoussa, R., Cottrell, G., Le Port, A., Theisen, M., Remarque, E. J., Longacre, S., Moutairou, K., Massougbodji, A., Luty, A. J. F., Nuel, G., Migot-Nabias, F., Sanni, A., Garcia, A., Milet, J. & 1 others, Courtin, D., 2019, In: Malaria Journal. 18, 11 p., 194.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Antibody responses to antigenic targets of recent exposure are associated with low-density parasitemia in controlled human Plasmodium falciparum infections

    van den Hoogen, L. L., Walk, J., Oulton, T., Reuling, I. J., Reiling, L., Beeson, J. G., Coppel, R. L., Singh, S. K., Draper, S. J., Bousema, T., Drakeley, C., Sauerwein, R. & Tetteh, K. K. A., 2019, In: Frontiers in Microbiology. 9, 11 p., 3300.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Breadth of functional antibodies is associated with Plasmodium falciparum merozoite phagocytosis and protection against febrile malaria

    Kana, Ikhlaq Hussain, Singh, S. K., Garcia-Senosiain, A., Dodoo, D., Singh, S., Adu, B. & Theisen, Michael, 2019, In: The Journal of Infectious Diseases. 220, 2, p. 275-284 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Controlled human malaria infection of healthy adults with lifelong malaria exposure to assess safety, immunogenicity, and efficacy of the asexual blood stage malaria vaccine candidate GMZ2

    Dejon-Agobe, J. C., Ateba-Ngoa, U., Lalremruata, A., Homoet, A., Engelhorn, J., Nouatin, O. P., Edoa, J. R., Fernandes, J. F., Esen, M., Mouwenda, Y. D., Betouke Ongwe, E. M., Massinga-Loembe, M., Hoffman, S. L., Sim, B. K. L., Theisen, Michael, Kremsner, P. G., Adegnika, A. A., Lell, B. & Mordmüller, B., 2019, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 69, 8, p. 1377-1384 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Immunogenicity of a recombinant fusion construct composed of intrinsically unstructured, low polymorphic segments derived from merozoite surface protein 2 and trophozoite exported protein 1

    Tiendrebeogo, R. W., Spallek, R., Oehlmann, W., Singh, M., Theisen, Michael, Nebie, I., Moret, R., Roussilhon, C. & Corradin, G., 2019, In: Vaccine. 37, 36, p. 5332-5340 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Optimisation and standardisation of a multiplex immunoassay of diverse plasmodium falciparum antigens to assess changes in malaria transmission using sero-epidemiology

    Wu, L., Hall, T., Ssewanyana, I., Oulton, T., Patterson, C., Vasileva, H., Singh, S., Affara, M., Mwesigwa, J., Correa, S., Bah, M., D'alessandro, U., Sepúlveda, N., Drakeley, C. & Tetteh, K. K. A., 2019, In: Wellcome Open Research. 4, 26.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Pfs230 and Pfs48/45 fusion proteins elicit strong transmission-blocking antibody responses against Plasmodium falciparum

    Singh, S. K., Thrane, Susan, Chourasia, B. K., Teelen, K., Graumans, W., Stoter, R., van Gemert, G., van de Vegte-Bolmer, M. G., Nielsen, Morten Agertoug, Salanti, Ali, Sander, Adam F. , Sauerwein, R. W., Jore, M. M. & Theisen, Michael, 2019, In: Frontiers in Immunology. 10, 1256.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    The candidate blood-stage malaria vaccine P27A induces a robust humoral response in a fast track to the field Phase 1 trial in exposed and nonexposed volunteers

    Steiner-Monard, V., Kamaka, K., Karoui, O., Roethlisberger, S., Audran, R., Daubenberger, C., Fayet-Mello, A., Erdmann-Voisin, A., Felger, I., Geiger, K., Govender, L., Houard, S., Huber, E., Mayor, C., Mkindi, C., Portevin, D., Rusch, S., Schmidlin, S., Tiendrebeogo, R. W., Theisen, M. & 9 others, Thierry, A., Vallotton, L., Corradin, G., Leroy, O., Abdulla, S., Shekalaghe, S., Genton, B., Spertini, F. & Jongo, S. A., 2019, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 68, 3, p. 466-474 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review