- 2021
- Published
Exploratory analysis of the effect of helminth infection on the immunogenicity and efficacy of the asexual blood-stage malaria vaccine candidate GMZ2
Nouatin, O., Mengue, J. B., Dejon-Agobé, J. C., Fendel, R., Ibáñez, J., Ngoa, U. A., Edoa, J. R., Adégbité, B. R., Honkpéhédji, Y. J., Zinsou, J. F., Hounkpatin, A. B., Moutairou, K., Homoet, A., Esen, M., Kreidenweiss, A., Hoffman, S. L., Theisen, M., Luty, A. J. F., Lell, B., Agnandji, S. T. & 5 others, , 2021, In: PLoS Neglected Tropical Diseases. 15, 6, 18 p., e0009361.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extended follow-up of children in a phase2b trial of the GMZ2 malaria vaccine
Dassah, S., Adu, B., Sirima, S. B., Mordmüller, B., Ngoa, U. A., Atuguba, F., Arthur, F. K. N., Mensah, B. A., Kaddumukasa, M., Bang, P., Kremsner, P. G., Mategula, D., Flach, C., Milligan, P. & Theisen, Michael, 2021, In: Vaccine. 39, 31, p. 4314-4319 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of single-nucleotide polymorphisms in the mitochondrial genome and kelch 13 gene of Plasmodium falciparum in different geographical populations
Nydahl, T. K., Ahorhorlu, S. Y., Ndiaye, M., Das, M. K., Hansson, Helle Smedegaard, Crespo Bravo, Marina, Wang, Christian William, Lusingu, J., Theisen, Michael, Singh, S. K., Singh, S., Campino, S., Lund, O., Roper, C. & Alifrangis, Michael, 2021, In: American Journal of Tropical Medicine and Hygiene. 105, 4, p. 1085-1092 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neutrophils dominate in opsonic phagocytosis of P. falciparum blood-stage merozoites and protect against febrile malaria
Garcia-Senosiain, A., Kana, Ikhlaq Hussain, Singh, S., Das, M. K., Dziegiel, Morten Hanefeld, Hertegonne, S., Adu, B. & Theisen, Michael, 2021, In: Communications Biology . 4, 984.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preclinical development of a Pfs230-Pfs48/45 chimeric malaria transmission-blocking vaccine
Singh, S. K., Plieskatt, J., Chourasia, B. K., Singh, V., Bengtsson, K. L., Reimer, J. M., van Daalen, R. C., Teelen, K., van de Vegte-Bolmer, M., van Gemert, G., Jore, M. M. & Theisen, Michael, 2021, In: npj Vaccines. 6, 11 p., 120.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Suitability of IgG responses to multiple Plasmodium falciparum antigens as markers of transmission intensity and pattern
Kyei-Baafour, E., Oppong, M., Kusi, K. A., Frempong, A. F., Aculley, B., Arthur, F. K. N., Tiendrebeogo, R. W., Singh, S. K., Theisen, Michael, Kweku, M., Adu, B., Hviid, Lars & Ofori, M. F., 2021, In: PLoS ONE. 16, 4, e0249936.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Effect of immune regulatory pathways after immunization with GMZ2 malaria vaccine candidate in healthy lifelong malaria-exposed adults
Nouatin, O., Ateba Ngoa, U., Ibáñez, J., Dejon-Agobe, J. C., Mordmüller, B., Edoa, J. R., Mougeni, F., Brückner, S., Bouyoukou Hounkpatin, A., Esen, M., Theisen, Michael, Moutairou, K., Hoffman, S. L., Issifou, S., Luty, A. J. F., Loembe, M. M., Agnandji, S. T., Lell, B., Kremsner, P. G. & Adegnika, A. A., 2 Jun 2020, In: Vaccine. 38, 27, p. 4263-4272 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasmodium falciparum Clag9-associated PfRhopH complex is involved in merozoite binding to human erythrocytes
Chourasia, B. K., Deshmukh, A., Kaur, I., Paul, G., Panda, A., Rathore, S., Singh, S. K., Theisen, Michael, Mohmmed, A. & Malhotra, P., 2020, In: Infection and Immunity. 88, 2, e00504-19.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibody responses to a suite of novel serological markers for malaria surveillance demonstrate strong correlation with clinical and parasitological infection across seasons and transmission settings in The Gambia
Wu, L., Mwesigwa, J., Affara, M., Bah, M., Correa, S., Hall, T., Singh, S. K., Beeson, J. G., Tetteh, K. K. A., Kleinschmidt, I., D'Alessandro, U. & Drakeley, C., 2020, In: BMC Medicine. 18, 1, 304.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of Commercial ELISA Kits to Confirm the Absence of Transmission in Malaria Elimination Settings
van den Hoogen, L. L., Bareng, P., Alves, J., Reyes, R., Macalinao, M., Rodrigues, J. M., Fernandes, J. M., Goméz, L. F., Hall, T., Singh, S. K., Fornace, K., Luchavez, J., Kitchen, A., Chiodini, P., Espino, F., Tetteh, K. K. A., Stresman, G., Sepúlveda, N. & Drakeley, C., 2020, In: Frontiers in Public Health. 8, 480.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluating the predictive performance of malaria antibodies and FCGR3B gene polymorphisms on Plasmodium falciparum infection outcome: a prospective cohort study
Dwomoh, D., Adu, B., Dodoo, D., Theisen, Michael, Iddi, S. & Gerds, Thomas Alexander, 2020, In: Malaria Journal. 19, 1, 12 p., 307.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microscopic and submicroscopic asymptomatic Plasmodium falciparum infections in Ghanaian children and protection against febrile malaria
Adu, B., Issahaque, Q., Sarkodie-Addo, T., Kumordjie, S., Kyei-Baafour, E., Sinclear, C. K., Eyia-Ampah, S., Owusu-Yeboa, E., Theisen, Michael & Dodoo, D., 2020, In: Infection and Immunity. 88, 10, e00125-20.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peripheral Merozoite Surface Proteins Are Targets of Naturally Acquired Immunity against Malaria in both India and Ghana
Garcia-Senosiain, A., Kana, Ikhlaq Hussain, Singh, S. K., Chourasia, B. K., Das, M. K., Dodoo, D., Singh, S., Adu, B. & Theisen, Michael, 2020, In: Infection and Immunity. 88, 4, e00778-19.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selection of antibody responses associated with Plasmodium falciparum infections in the context of malaria elimination
van den Hoogen, L. L., Stresman, G., Présumé, J., Romilus, I., Mondélus, G., Elismé, T., Existe, A., Hamre, K. E. S., Ashton, R. A., Druetz, T., Joseph, V., Beeson, J. G., Singh, S. K., Boncy, J., Eisele, T. P., Chang, M. A., Lemoine, J. F., Tetteh, K. K. A., Rogier, E. & Drakeley, C., 2020, In: Frontiers in Immunology. 11, 12 p., 928.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sero-epidemiological evaluation of malaria transmission in The Gambia before and after mass drug administration
Wu, L., Mwesigwa, J., Affara, M., Bah, M., Correa, S., Hall, T., Singh, S. K., Beeson, J. G., Tetteh, K. K. A., Kleinschmidt, I., D’Alessandro, U. & Drakeley, C., 2020, In: BMC Medicine. 18, 331.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stage-specific Plasmodium falciparum immune responses in afebrile adults and children living in the Greater Accra Region of Ghana
Acquah, F. K., Lo, A. C., Akyea-Mensah, K., Abagna, H. B., Faye, B., Theisen, Michael, Gyan, B. A. & Amoah, L. E., 2020, In: Malaria Journal. 19, 1, 11 p., 64.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Plasmodium falciparum circumsporozoite protein produced in Lactococcus lactis is pure and stable
Singh, S. K., Plieskatt, J., Chourasia, B. K., Singh, V., Bolscher, J. M., Dechering, K. J., Adu, B., López-Méndez, B., Kaviraj, S., Locke, E., King, C. R. & Theisen, Michael, 2020, In: Journal of Biological Chemistry. 295, 2, p. 403-414 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Plasmodium falciparum merozoite surface antigen-specific cytophilic IgG and control of malaria infection in a Beninese birth cohort
Adamou, R., Dechavanne, C., Sadissou, I., d'Almeida, T., Bouraima, A., Sonon, P., Amoussa, R., Cottrell, G., Le Port, A., Theisen, M., Remarque, E. J., Longacre, S., Moutairou, K., Massougbodji, A., Luty, A. J. F., Nuel, G., Migot-Nabias, F., Sanni, A., Garcia, A., Milet, J. & 1 others, , 2019, In: Malaria Journal. 18, 11 p., 194.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibody responses to antigenic targets of recent exposure are associated with low-density parasitemia in controlled human Plasmodium falciparum infections
van den Hoogen, L. L., Walk, J., Oulton, T., Reuling, I. J., Reiling, L., Beeson, J. G., Coppel, R. L., Singh, S. K., Draper, S. J., Bousema, T., Drakeley, C., Sauerwein, R. & Tetteh, K. K. A., 2019, In: Frontiers in Microbiology. 9, 11 p., 3300.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Breadth of functional antibodies is associated with Plasmodium falciparum merozoite phagocytosis and protection against febrile malaria
Kana, Ikhlaq Hussain, Singh, S. K., Garcia-Senosiain, A., Dodoo, D., Singh, S., Adu, B. & Theisen, Michael, 2019, In: The Journal of Infectious Diseases. 220, 2, p. 275-284 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Controlled human malaria infection of healthy adults with lifelong malaria exposure to assess safety, immunogenicity, and efficacy of the asexual blood stage malaria vaccine candidate GMZ2
Dejon-Agobe, J. C., Ateba-Ngoa, U., Lalremruata, A., Homoet, A., Engelhorn, J., Nouatin, O. P., Edoa, J. R., Fernandes, J. F., Esen, M., Mouwenda, Y. D., Betouke Ongwe, E. M., Massinga-Loembe, M., Hoffman, S. L., Sim, B. K. L., Theisen, Michael, Kremsner, P. G., Adegnika, A. A., Lell, B. & Mordmüller, B., 2019, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 69, 8, p. 1377-1384 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunogenicity of a recombinant fusion construct composed of intrinsically unstructured, low polymorphic segments derived from merozoite surface protein 2 and trophozoite exported protein 1
Tiendrebeogo, R. W., Spallek, R., Oehlmann, W., Singh, M., Theisen, Michael, Nebie, I., Moret, R., Roussilhon, C. & Corradin, G., 2019, In: Vaccine. 37, 36, p. 5332-5340 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Optimisation and standardisation of a multiplex immunoassay of diverse plasmodium falciparum antigens to assess changes in malaria transmission using sero-epidemiology
Wu, L., Hall, T., Ssewanyana, I., Oulton, T., Patterson, C., Vasileva, H., Singh, S., Affara, M., Mwesigwa, J., Correa, S., Bah, M., D'alessandro, U., Sepúlveda, N., Drakeley, C. & Tetteh, K. K. A., 2019, In: Wellcome Open Research. 4, 26.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pfs230 and Pfs48/45 fusion proteins elicit strong transmission-blocking antibody responses against Plasmodium falciparum
Singh, S. K., Thrane, Susan, Chourasia, B. K., Teelen, K., Graumans, W., Stoter, R., van Gemert, G., van de Vegte-Bolmer, M. G., Nielsen, Morten Agertoug, Salanti, Ali, Sander, Adam F. , Sauerwein, R. W., Jore, M. M. & Theisen, Michael, 2019, In: Frontiers in Immunology. 10, 1256.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The candidate blood-stage malaria vaccine P27A induces a robust humoral response in a fast track to the field Phase 1 trial in exposed and nonexposed volunteers
Steiner-Monard, V., Kamaka, K., Karoui, O., Roethlisberger, S., Audran, R., Daubenberger, C., Fayet-Mello, A., Erdmann-Voisin, A., Felger, I., Geiger, K., Govender, L., Houard, S., Huber, E., Mayor, C., Mkindi, C., Portevin, D., Rusch, S., Schmidlin, S., Tiendrebeogo, R. W., Theisen, M. & 9 others, , 2019, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 68, 3, p. 466-474 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural antibody responses to Plasmodium falciparum MSP3 and GLURP(R0) antigens are associated with low parasite densities in malaria patients living in the Central Region of Ghana
Research output: Contribution to journal › Journal article › Research › peer-review
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228
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Construct design, production, and characterization of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine
Research output: Contribution to journal › Journal article › Research › peer-review
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206
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Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity
Research output: Contribution to journal › Journal article › Research › peer-review
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Clinical formulation development of Plasmodium falciparum malaria vaccine candidates based on Pfs48/45, Pfs230, and PfCSP
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A Pfs48/45-based vaccine to block Plasmodium falciparum transmission: phase 1, open-label, clinical trial
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A randomized first-in-human phase I trial of differentially adjuvanted Pfs48/45 malaria vaccines in Burkinabé adults
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