TARGETS team

  1. 2005
  2. Published

    Carrageenans inhibit the in vitro growth of Plasmodium falciparum and cytoadhesion to CD36

    Adams, Yvonne, Smith, S. L., Schwartz-Albiez, R. & Andrews, K. T., Oct 2005, In: Parasitology Research. 97, 4, p. 290-294 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2006
  4. Published

    Rational design of anticytoadherence inhibitors for Plasmodium falciparum based on the crystal structure of human intercellular adhesion molecule 1

    Dormeyer, M., Adams, Yvonne, Kramer, B., Chakravorty, S., Tse, M. T., Pegoraro, S., Whittaker, L., Lanzer, M. & Craig, A., Feb 2006, In: Antimicrobial Agents and Chemotherapy. 50, 2, p. 724-730 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Inhibition of Plasmodium falciparum growth in vitro and adhesion to chondroitin-4-sulfate by the heparan sulfate mimetic PI-88 and other sulfated oligosaccharides

    Adams, Yvonne, Freeman, C., Schwartz-Albiez, R., Ferro, V., Parish, C. R. & Andrews, K. T., Aug 2006, In: Antimicrobial Agents and Chemotherapy. 50, 8, p. 2850-2852 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2007
  7. Published

    3D7-derived Plasmodium falciparum erythrocyte membrane protein 1 is a frequent target of naturally acquired antibodies recognizing protein domains in a particular pattern independent of malaria transmission intensity

    Joergensen, L., Vestergaard, L. S., Turner, Louise, Magistrado, P., Lusingu, J. P., Lemnge, M., Theander, Thor Grundtvig & Jensen, Anja Ramstedt, 2007, In: Journal of Immunology. 178, 1, p. 428-35 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Immunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malaria

    Magistrado, P. A., Lusingu, J., Vestergaard, L. S., Lemnge, M., Lavstsen, Thomas, Turner, Louise, Hviid, Lars, Jensen, Anja Ramstedt & Theander, Thor Grundtvig, 2007, In: Infection and Immunity. 75, 5, p. 2415-20 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Potential impact of host immunity on malaria treatment outcome in Tanzanian children infected with Plasmodium falciparum

    Enevold, A., Nkya, W. M. M. M., Theisen, M., Vestergaard, L. S., Jensen, Anja Ramstedt, Staalsoe, T., Theander, Thor Grundtvig, Bygbjerg, Ib Christian & Alifrangis, Michael, 2007, In: Malaria Journal. 6, p. 153

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Regioselectively modified sulfated cellulose as prospective drug for treatment of malaria tropica

    Schwartz-Albiez, R., Adams, Yvonne, Von Der Lieth, C. W., Mischnick, P., Andrews, K. T. & Kirschfink, M., Jan 2007, In: Glycoconjugate Journal. 24, 1, p. 57-65 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Effect of cytokine treatment on the in vitro expression of the P. falciparum adhesion receptor chondroitin-4-sulphate on the surface of human choriocarcinoma (BeWo) cells

    Adams, Yvonne, Schwartz-Albiez, R., McCarthy, J. S. & Andrews, K. T., Jul 2007, In: Parasitology Research. 101, 2, p. 479-483 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2008
  13. Published

    A method for visualizing surface-exposed and internal PfEMP1 adhesion antigens in Plasmodium falciparum infected erythrocytes

    Bengtsson, D., Sowa, K. M., Salanti, Ali, Jensen, Anja Ramstedt, Joergensen, L., Turner, Louise, Theander, Thor Grundtvig & Arnot, D. E., 2008, In: Malaria Journal. 7, p. 101

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    A semi-automated multiplex high-throughput assay for measuring IgG antibodies against Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) domains in small volumes of plasma

    Cham, G. K. K., Kurtis, J., Lusingu, J., Theander, Thor Grundtvig, Jensen, Anja Ramstedt & Turner, Louise, 2008, In: Malaria Journal. 7, p. 108

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    CD36 selection of 3D7 Plasmodium falciparum associated with severe childhood malaria results in reduced VAR4 expression

    Magistrado, P., Staalsoe, T., Theander, Thor Grundtvig, Hviid, Lars & Jensen, Anja Ramstedt, 2008, In: Malaria Journal. 7, 1, p. 204

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2009
  17. Published

    Sequential, ordered acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 domains

    Cham, G. K. K., Turner, Louise, Lusingu, J., Vestergaard, L., Mmbando, B. P., Kurtis, J. D., Jensen, Anja Ramstedt, Salanti, Ali, Lavstsen, Thomas & Theander, Thor Grundtvig, 2009, In: Journal of Immunology. 183, 5, p. 3356-63 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2010
  19. Published

    Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian children

    Cham, G. K. K., Turner, Louise, Kurtis, J. D., Mutabingwa, T., Fried, M., Jensen, Anja Ramstedt, Lavstsen, Thomas, Hviid, Lars, Duffy, P. E. & Theander, Thor Grundtvig, 2010, In: Infection and Immunity. 78, 11, p. 4653-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Insect cells are superior to Escherichia coli in producing malaria proteins inducing IgG targeting PfEMP1 on infected erythrocytes

    Victor, M. E., Bengtsson, A., Andersen, G., Bengtsson, D., Lusingu, J. P., Vestergaard, L. S., Arnot, D. E., Theander, Thor Grundtvig, Joergensen, L. & Jensen, Anja Ramstedt, 2010, In: Malaria Journal. 9, p. 325

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Surface co-expression of two different PfEMP1 antigens on single Plasmodium falciparum-infected erythrocytes facilitates binding to ICAM1 and PECAM1

    Joergensen, L., Bengtsson, D. C., Bengtsson, A., Ronander, E., Berger, S. S., Turner, Louise, Dalgaard, M. B., Cham, G. K. K., Victor, M. E., Lavstsen, Thomas, Theander, Thor Grundtvig, Arnot, D. E. & Jensen, Anja Ramstedt, 2010, In: PLoS Pathogens. 6, 9, p. e1001083

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2011
  23. Published

    Antigenic variation and the genetics and epigenetics of the PfEMP1 erythrocyte surface antigens in Plasmodium falciparum malaria

    Arnot, D. E. & Jensen, Anja Ramstedt, 2011, In: Advances in Applied Microbiology. 74, p. 77-96 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2012
  25. Published

    Analysis of Single-cell Gene Transcription by RNA Fluorescent In Situ Hybridization (FISH)

    Ronander, E., Bengtsson, D. C., Joergensen, L., Jensen, Anja Ramstedt & Arnot, D. E., 2012, In: Journal of Visualized Experiments. 68

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Induction of strain-transcending antibodies against group A PfEMP1 surface antigens from virulent malaria parasites

    Ghumra, A., Semblat, J. P., Ataide, R., Kifude, C., Adams, Yvonne, Claessens, A., Anong, D. N., Bull, P. C., Fennell, C., Arman, M., Amambua-Ngwa, A., Walther, M., Conway, D. J., Kassambara, L., Doumbo, O. K., Raza, A. & Rowe, J. A., Apr 2012, In: PLoS Pathogens. 8, 4, e1002665.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2013
  28. Published

    A Novel Domain Cassette Identifies Plasmodium falciparum PfEMP1 Proteins Binding ICAM-1 and Is a Target of Cross-Reactive, Adhesion-Inhibitory Antibodies

    Bengtsson, A., Joergensen, L., Rask, T. S., Olsen, R. W., Andersen, M. A., Turner, Louise, Theander, Thor Grundtvig, Hviid, Lars, Higgins, M. K., Craig, A., Brown, A. & Jensen, Anja Ramstedt, 2013, In: Journal of Immunology. 190, 1, p. 240-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Transfected HEK293 Cells Expressing Functional Recombinant Intercellular Adhesion Molecule 1 (ICAM-1) - A Receptor Associated with Severe Plasmodium falciparum Malaria

    Bengtsson, A., Joergensen, L., Barbati, Z. R., Craig, A., Hviid, Lars & Jensen, Anja Ramstedt, 2013, In: PLOS ONE. 8, 7, p. e69999

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    A Method for Positive and Negative Selection of Plasmodium falciparum Platelet-Mediated Clumping Parasites and Investigation of the Role of CD36

    Arman, M., Adams, Yvonne, Lindergard, G. & Rowe, J. A., 6 Feb 2013, In: PLoS ONE. 8, 2, e55453.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    The Effect of Anti-Rosetting Agents against Malaria Parasites under Physiological Flow Conditions

    Adams, Yvonne & Rowe, J. A., 16 Sep 2013, In: PLoS ONE. 8, 9, e73999.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2014
  33. Published

    An analysis of the binding characteristics of a panel of recently selected ICAM-1 binding Plasmodium falciparum patient isolates

    Madkhali, A. M., Alkurbi, M. O., Szestak, T., Bengtsson, A., Patil, P. R., Wu, Y., Alharthi, S., Jensen, Anja Ramstedt, Pleass, R. & Craig, A. G., 2014, In: PLOS ONE. 9, 10, 8 p., e111518.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria

    Zhang, Q., Siegel, T. N., Martins, R. M., Wang, F., Cao, J., Gao, Q., Cheng, X., Jiang, L., Hon, C., Scheidig-Benatar, C., Sakamoto, H., Turner, Louise, Jensen, Anja Ramstedt, Claes, A., Guizetti, J., Malmquist, N. A. & Scherf, A., 2014, In: Nature. 531, p. 431-435

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Rosetting Plasmodium falciparum-infected erythrocytes bind to human brain microvascular endothelial cells in vitro, demonstrating a dual adhesion phenotype mediated by distinct P. falciparum erythrocyte membrane protein 1 domains

    Adams, Yvonne, Kuhnrae, P., Higgins, M. K., Ghumra, A. & Rowe, J. A., Mar 2014, In: Infection and Immunity. 82, 3, p. 949-959 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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