Centre for Medical Parasitology

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  1. Published

    Drugs for the neglected disease malaria based on natural products

    Christensen, Søren Brøgger & Bygbjerg, Ib Christian, 2012, Bioactive compounds from natural sources: natural products as lead compounds in drug discovery. Tringali, C. (ed.). 2 ed. Boca Raton: CRC Press, p. 525-550

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  2. Published

    Dual fluorescence labeling of surface-exposed and internal proteins in erythrocytes infected with the malaria parasite Plasmodium falciparum

    Bengtsson, D. C., Sowa, K. M. P. & Arnot, D. E., 2008, In: Nature Protocols (Print Edition). 3, 12, p. 1990-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Dual stage synthesis and crucial role of cytoadherence-linked asexual gene 9 in the surface expression of malaria parasite var proteins

    Goel, S., Valiyaveettil, M., Achur, R. N., Goyal, A., Mattei, D., Salanti, Ali, Trenholme, K. R., Gardiner, D. L. & Gowda, D. C., 2010, In: Proceedings of the National Academy of Science of the United States of America. 107, 38, p. 16643-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Dynamics of anti-MSP3 and Pfs230 antibody responses and multiplicity of infection in asymptomatic children from southern Ghana

    Amoah, L. E., Acquah, F. K., Ayanful-Torgby, R., Oppong, A., Abankwa, J., Obboh, E. K., Singh, S. K. & Theisen, Michael, 5 Jan 2018, In: Parasites & Vectors. 11, 1, 9 p., 13.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Dynamics of anti-VAR2CSA immunoglobulin G response in a cohort of senegalese pregnant women

    Tuikue Ndam, N. G., Salanti, Ali, Le-Hesran, J., Cottrell, G., Fievet, N., Turner, Louise, Sow, S., Dangou, J., Theander, Thor Grundtvig & Deloron, P., 2006, In: Journal of Infectious Diseases. 193, 5, p. 713-20 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    EBI2 overexpression in mice leads to B1 B cell expansion and chronic lymphocytic leukemia-(CLL)-like B cell malignancies

    Niss Arfelt, K., Barington, L., Benned-Jensen, T., Kubale, V., Kovalchuk, A. L., Daugvilaite, V., Christensen, Jan Pravsgaard, Thomsen, Allan Randrup, Egerod, Kristoffer Lihme, Bassi, Maria Rosaria, Spiess, Katja, Schwartz, Thue W., Wang, H., Morse, H. C., Holst, Peter Johannes & Rosenkilde, Mette, 2017, In: Blood. 129, 7, p. 866-878

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Early gametocytes of the malaria parasite Plasmodium falciparum specifically remodel the adhesive properties of infected erythrocyte surface

    Tibúrcio, M., Silvestrini, F., Bertuccini, L., Sander, Adam F. , Turner, Louise, Lavstsen, Thomas & Alano, P., 1 Nov 2013, In: Cellular Microbiology Online. 15, 4, p. 647-659

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Early home-based recognition of anaemia via general danger signs, in young children, in a malaria endemic community in north-east Tanzania

    Ringsted, F. M., Bygbjerg, Ib Christian & Samuelsen, Helle, 2006, In: Malaria Journal. 5, p. 111

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Early immune response in susceptible and resistant mice strains with chronic Pseudomonas aeruginosa lung infection determines the type of T-helper cell response

    Moser, C., Hougen, H. P., Song, Z., Rygaard, J., Kharazmi, A. & Høiby, Niels, 1999, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 107, 12, p. 1093-100 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Early life vaccination: Generation of adult-quality memory CD8+ T cells in infant mice using non-replicating adenoviral vectors

    Nazerai, L., Bassi, Maria Rosaria, Uddbäck, Ida Elin Maria, Holst, Peter Johannes, Christensen, Jan Pravsgaard & Thomsen, Allan Randrup, 8 Dec 2016, In: Scientific Reports. 6, 17 p., 38666.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Effect of Legionella pneumophila cytotoxic protease on human neutrophil and monocyte function

    Rechnitzer, C. & Kharazmi, A., 1992, In: Microbial Pathogenesis. 12, 2, p. 115-25 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Effect of HIV-1 envelope cytoplasmic tail on adenovirus primed virus encoded virus-like particle immunizations

    Andersson, A. M. C., Ragonnaud, Emeline, Seaton, K. E., Sawant, S., Folgori, A., Colloca, S., Labranche, C., Montefiori, D. C., Tomaras, G. D. & Holst, Peter Johannes, 17 Oct 2016, In: Vaccine. 34, 44, p. 5344-5351 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Effect of a community-based delivery of intermittent preventive treatment of malaria in pregnancy on treatment seeking for malaria at health units in Uganda

    Mbonye, A. K., Schultz Hansen, K., Bygbjerg, Ib Christian & Magnussen, Pascal, 2008, In: Public Health. 122, 5, p. 516-25 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Effect of concomitant artesunate administration and cytochrome P4502C8 polymorphisms on the pharmacokinetics of amodiaquine in Ghanaian children with uncomplicated malaria

    Adjei, G. O., Kristensen, K., Goka, B. Q., Hoegberg, L. C. G., Alifrangis, Michael, Rodrigues, O. P. & Kurtzhals, J. A. L., 2008, In: Antimicrobial Agents and Chemotherapy. 52, 12, p. 4400-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Effect of ginseng treatment on neutrophil chemiluminescence and IgG subclasses in a rat model of chronic Pseudomonas aeruginosa pneumonia

    Song, Z., Kharazmi, A., Wu, H., Moser, C., Johansen, Helle Krogh, Faber, V., Rygaard, J. & Høiby, Niels, 1998, In: Clinical and Vaccine Immunology. 5, p. 882-887

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Effect of ingested human antibodies induced by RTS, S/AS01 malaria vaccination in children on Plasmodium falciparum oocyst formation and sporogony in mosquitoes

    Miura, K., Jongert, E., Deng, B., Zhou, L., Lusingu, J. P., Drakeley, C. J., Fay, M. P., Long, C. A. & Vekemans, J., 2014, In: Malaria Journal. 13, p. 1-9 9 p., 263.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Effect of intermittent treatment with amodiaquine on anaemia and malarial fevers in infants in Tanzania: a randomised placebo-controlled trial

    Massaga, J. J., Kitua, A. Y., Lemnge, M. M., Akida, J. A., Malle, L. N., Rønn, A. M., Theander, Thor Grundtvig & Bygbjerg, Ib Christian, 2003, In: Lancet. 361, 9372, p. 1853-60 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Effect of national schistosomiasis control programme on Taenia solium taeniosis and porcine cysticercosis in rural communities of Tanzania

    Braae, U. C., Magnussen, Pascal, Harrison, W., Ndawi, B., Lekule, F. & Johansen, M. V., Sep 2016, In: Parasite Epidemiology and Control. 1, 3, p. 245-251 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Effect of repeated mass drug administration with praziquantel and track and treat of taeniosis cases on the prevalence of taeniosis in Taenia solium endemic rural communities of Tanzania

    Braae, U. C., Magnussen, Pascal, Ndawi, B., Wendy, H., Lekule, F. P. & Johansen, M. V., Jan 2017, In: Acta Tropica. 165, p. 246-251

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Effect of repeated mass drug administration with praziquantel and track and treat of taeniosis cases on the prevalence of taeniosis in Taenia solium endemic rural communities of Tanzania

    Braae, U. C., Magnussen, Pascal, Ndawi, B., Wendy, H., Lekule, F. & Johansen, M. V., 3 Nov 2015.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  21. Published

    Effect of streptokinase on human neutrophil function in vitro and in patients with acute myocardial infarction

    Hansen, P. R. & Kharazmi, A., 1994, In: Journal of Molecular and Cellular Cardiology. 26, 8, p. 1061-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Effect of the pre-erythrocytic candidate malaria vaccine RTS,S/AS01E on blood stage immunity in young children

    Bejon, P., Cook, J., Bergmann-Leitner, E., Olotu, A., Lusingu, J., Mwacharo, J., Vekemans, J., Njuguna, P., Leach, A., Lievens, M., Dutta, S., von Seidlein, L., Savarese, B., Villafana, T., Lemnge, M. M., Cohen, J., Marsh, K., Corran, P. H., Angov, E., Riley, E. M. & 1 others, Drakeley, C. J., 2011, In: Journal of Infectious Diseases. 204, 1, p. 9-18 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Effects of pregnancy and intensity of Plasmodium falciparum transmission on immunoglobulin G subclass responses to variant surface antigens

    Megnekou, R., Staalsoe, T., Taylor, D. W., Leke, R. & Hviid, Lars, 2005, In: Infection and Immunity. 73, 7, p. 4112-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Effects of the vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitor SU5416 on in vitro cultures of Plasmodium falciparum

    Hempel, C., Hoyer, N., Staalsø, Trine & Kurtzhals, Jørgen, 2014, In: Malaria Journal. 13, 1, p. 201

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Efficacies of artesunate plus either sulfadoxine-pyrimethamine or amodiaquine, for the treatment of uncomplicated, Plasmodium falciparum malaria in eastern Sudan

    Ibrahium, A. M., Kheir, M. M., Osman, M. E., Khalil, I. F., Alifrangis, Michael, Elmardi, K. A., Malik, E. M. & Adam, I., 2007, In: Annals of Tropical Medicine and Parasitology. 101, 1, p. 15-21 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Efficacy and Safety of the RTS,S/AS01 Malaria Vaccine during 18 Months after Vaccination: A Phase 3 Randomized, Controlled Trial in Children and Young Infants at 11 African Sites

    Theander, Thor Grundtvig, Lusingu, J. P. A. & RTS,S Clinical Trials Partnership, R. C. T. P., Jul 2014, In: P L o S Medicine (Online). 11, 7, p. 1-24 24 p., e1001685.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial

    RTS,S Clinical Trials Partnership, R. C. T. P., 4 Jul 2015, In: Lancet. 386, 9988, p. 31-45 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Efficacy of RTS,S/AS01E malaria vaccine and exploratory analysis on anti-circumsporozoite antibody titres and protection in children aged 5-17 months in Kenya and Tanzania: a randomised controlled trial

    Olotu, A., Lusingu, J., Leach, A., Lievens, M., Vekemans, J., Msham, S., Lang, T., Gould, J., Dubois, M-C., Jongert, E., Vansadia, P., Carter, T., Njuguna, P., Awuondo, K. O., Malabeja, A., Abdul, O., Gesase, S., Mturi, N., Drakeley, C. J., Savarese, B. & 10 others, Villafana, T., Lapierre, D., Ballou, W. R., Cohen, J., Lemnge, M. M., Peshu, N., Marsh, K., Riley, E. M., von Seidlein, L. & Bejon, P., 2011, In: Lancet Infectious Diseases. 11, 2, p. 102-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age

    Bejon, P., Lusingu, J., Olotu, A., Leach, A., Lievens, M., Vekemans, J., Mshamu, S., Lang, T., Gould, J., Dubois, M-C., Demoitié, M-A., Stallaert, J-F., Vansadia, P., Carter, T., Njuguna, P., Awuondo, K. O., Malabeja, A., Abdul, O., Gesase, S., Mturi, N. & 9 others, Drakeley, C. J., Savarese, B., Villafana, T., Ballou, W. R., Cohen, J., Riley, E. M., Lemnge, M. M., Marsh, K. & von Seidlein, L., 2008, In: New England Journal of Medicine. 359, 24, p. 2521-32 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Efficacy of chloroquine, amodiaquine, sulphadoxine-pyrimethamine and combination therapy with artesunate in Mozambican children with non-complicated malaria

    Abacassamo, F., Enosse, S., Aponte, J. J., Gómez-Olivé, F. X., Quintó, L., Mabunda, S., Barreto, A., Magnussen, Pascal, Rønn, A. M., Thompson, R. & Alonso, P. L., 2004, In: Tropical Medicine & International Health. 9, 2, p. 200-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Efficacy of the GMZ2 malaria vaccine in African children

    Milligan, P., Flach, C. & Theisen, Michael, 5 Jan 2017, In: Vaccine. 35, 2, p. 202 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  32. Published

    Efficacy, Safet and Costs of Intermittent Presumptive Treatment for Malaria in Tanzania: Beliefs, Attitudes, Experiences, and Views of Service Providers and Users

    Mubyazi, G. M., Bloch, P., Magnussen, Pascal, Byskov, J., Hansen, K. S., Olsen, Ø. E., Mboera, L. E. G. & Bygbjerg, Ib Christian, 2009, Antimalarial Drugs, Costs, Safety and Efficacy: Tropical Diseases - Etiology, Pathogenesis and Treatments Series. New York: Nova Science Publishers, p. 1-29 29 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  33. Published

    Electrocardiographic study in Ghanaian children with uncomplicated malaria, treated with artesunate-amodiaquine or artemether-lumefantrine

    Adjei, G. O., Oduro-Boatey, C., Rodrigues, O. P., Hoegberg, L. C., Alifrangis, Michael, Kurtzhals, Jørgen & Goka, B. Q., 2012, In: Malaria Journal. 11, p. 420

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Elevated levels of nitric oxide and low levels of haptoglobin are associated with severe malarial anaemia in African children

    Gyan, B., Kurtzhals, Jørgen, Akanmori, B. D., Ofori, M., Goka, B. Q., Hviid, Lars & Behr, C., 2002, In: Acta Tropica. 83, 2, p. 133-40 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Elevated plasma urokinase receptor predicts low birth weight in maternal malaria

    Ostrowski, S. R., Shulman, C. E., Peshu, N., Staalsø, Trine, Høyer-Hansen, G., Pedersen, B. K., Marsh, K. & Ullum, H., 2007, In: Parasite Immunology. 29, 1, p. 37-46 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Eleven years of malaria surveillance in a Sudanese village highlights unexpected variation in individual disease susceptibility and outbreak severity

    Creasey, A., Giha, H., Hamad, A. A., El Hassan, I. M., Theander, Thor Grundtvig & Arnot, D. E., 2004, In: Parasitology. 129, Pt 3, p. 263-71 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Emerging implications of policies on malaria treatment: genetic changes in the Pfmdr-1 gene affecting susceptibility to artemether-lumefantrine and artesunate-amodiaquine in Africa

    Okell, L. C., Reiter, L. M., Ebbe, L. S., Baraka, V., Bisanzio, D., Watson, O. J., Bennett, A., Verity, R., Gething, P., Roper, C. & Alifrangis, Michael, 2018, In: BMJ Global Health. 3, 5, 12 p., e000999.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Endothelial glycocalyx: shedding light on malaria pathogenesis

    Hempel, C., Pasini, E. M. & Kurtzhals, Jørgen, Jun 2016, In: Trends in Molecular Medicine. 22, 6, p. 453-457 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Endothelial glycocalyx on brain endothelial cells is lost in experimental cerebral malaria

    Hempel, C., Hyttel, P. & Kurtzhals, Jørgen, Jul 2014, In: Journal of Cerebral Blood Flow and Metabolism. 34, 7, p. 1107-10 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Enhanced depletion of glutathione and increased liver oxidative damage in aflatoxin-fed mice infected with Plasmodium berghei

    Ankrah, N. A., Sittie, A., Addo, P. G. & Ekuban, F. A., 1995, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 89, 1, p. 59-61 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Eosinophil cationic protein in sputum from cystic fibrosis patients with Pseudomonas aeruginosa infections

    Reimert, C. M., Giwercman, B., Høiby, Niels & Kharazmi, A., 1994, In: Lancet. 344, 8935, p. 1504-5 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Eosinophil protein X/eosinophil derived neurotoxin (EPX/EDN). Detection by enzyme-linked immunosorbent assay and purification from normal human urine

    Reimert, C. M., Minuva, U., Kharazmi, A. & Bendtzen, K., 1991, In: Journal of Immunological Methods. 141, 1, p. 97-104 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Epidemiological Study of the Association Between Malaria and Helminth Infections in Nigeria

    Efunshile, A. M., Olawale, T., Stensvold, C. R., Kurtzhals, Jørgen & König, B., 2015, In: American Journal of Tropical Medicine and Hygiene. 92, 3, p. 578-82 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Epidemiology of taeniosis/cysticercosis in Europe, a systematic review: Western Europe

    Laranjo-González, M., Devleesschauwer, B., Trevisan, C., Allepuz, A., Sotiraki, S., Abraham, A., Afonso, M. B., Blocher, J., Cardoso, L., Correia Da Costa, J. M., Dorny, P., Gabriël, S., Gomes, J., Gómez-Morales, M. Á., Jokelainen, P., Kaminski, M., Krt, B., Magnussen, P., Robertson, L. J., Schmidt, V. & 12 others, Schmutzhard, E., Smit, G. S. A., Šoba, B., Stensvold, C. R., Starič, J., Troell, K., Rataj, A. V., Vieira-Pinto, M., Vilhena, M., Wardrop, N. A., Winkler, A. S. & Dermauw, V., 21 Jul 2017, In: Parasites and Vectors. 10, 14 p., 349.

    Research output: Contribution to journal › Review › Research › peer-review

  45. Published

    Epitope mapping and topographic analysis of VAR2CSA DBL3X involved in P. falciparum placental sequestration

    Dahlbäck, M., Rask, T. S., Andersen, P. H., Nielsen, Morten Agertoug, Ndam, N. T., Resende, M., Turner, Louise, Deloron, P., Hviid, Lars, Lund, O., Pedersen, A. G., Theander, Thor Grundtvig & Salanti, Ali, 2006, In: PLoS Pathogens. 2, 11, p. e124

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Erythropoietin treatment alleviates ultrastructural myelin changes induced by murine cerebral malaria

    Hempel, C., Hyttel, P., Staalsø, Trine, Nyengaard, J. R. & Kurtzhals, Jørgen, 2012, In: Malaria Journal. 11, 1, p. 216

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Estimates of burden and consequences of infants born small for gestational age in low and middle income countries with INTERGROWTH-21st standard: analysis of CHERG datasets

    Lee, A. C., Kozuki, N., Cousens, S., Stevens, G. A., Blencowe, H., Silveira, M. F., Sania, A., Rosen, H. E., Schmiegelow, C., Adair, L. S., Baqui, A. H., Barros, F. C., Bhutta, Z. A., Caulfield, L. E., Christian, P., Clarke, S. E., Fawzi, W., Gonzalez, R., Humphrey, J., Huybregts, L. & 20 others, Kariuki, S., Kolsteren, P., Lusingu, J., Manandhar, D., Mongkolchati, A., Mullany, L. C., Ndyomugyenyi, R., Nien, J. K., Roberfroid, D., Saville, N., Terlouw, D. J., Tielsch, J. M., Victora, C. G., Velaphi, S. C., Watson-Jones, D., Willey, B. A., Ezzati, M., Lawn, J. E., Black, R. E. & Katz, J., 2017, In: The BMJ. 358, 11 p., j3677.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Ethnomedicinal survey and in vitro anti-plasmodial activity of the palm Borassus aethiopum Mart

    Gruca, M., Yu, W., Amoateng, P., Nielsen, Morten Agertoug, Poulsen, T. B. & Balslev, H., 4 Dec 2015, In: Journal of Ethnopharmacology. 175, p. 356-369 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Etiology of placental Plasmodium falciparum malaria in African women

    Ofori, M. F., Lamptey, H., Dickson, E. K., Kyei-Baafour, E. & Hviid, Lars, 2018, In: The Journal of Infectious Diseases. 218, 2, p. 277-281 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Evaluation of the efficacy of Iran leishmanin and comparison with leishmanins from Wellcome (UK) and Roma (Italy) in cured cutaneous leishmaniasis patients

    Alimohammadian, M. H., Kivanjah, M., Pak, F., Gaznavia, A. & Kharazmi, A., 1994, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 87, 5, p. 550-1 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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