Centre for Medical Parasitology

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  1. 2005
  2. Published

    Rapid screening for glucose-6-phosphate dehydrogenase deficiency and haemoglobin polymorphisms in Africa by a simple high-throughput SSOP-ELISA method

    Enevold, A., Vestergaard, L. S., Lusingu, J., Drakeley, C. J., Lemnge, M. M., Theander, Thor Grundtvig, Bygbjerg, Ib Christian & Alifrangis, Michael, 2005, In: Malaria Journal. 4, p. 61

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Response of Plasmodium falciparum to cotrimoxazole therapy: relationship with plasma drug concentrations and dihydrofolate reductase and dihydropteroate synthase genotypes

    Khalil, I. F., Rønn, A. M., Alifrangis, Michael, Gabar, H. A., Jelinek, T., Satti, G. M. H. & Bygbjerg, Ib Christian, 2005, In: American Journal of Tropical Medicine and Hygiene. 73, 1, p. 174-7 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The roles of the pfcrt 76T and pfmdr1 86Y mutations, immunity and the initial level of parasitaemia, in predicting the outcome of chloroquine treatment in two areas with different transmission intensities

    Khalil, I. F., Alifrangis, Michael, Tarimo, D. S., Staalsø, T., Satti, G. M. H., Theander, Thor Grundtvig, Rønn, A. M. & Bygbjerg, Ib Christian, 2005, In: Annals of Tropical Medicine and Parasitology. 99, 5, p. 441-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The use of nominal group technique in identifying community health priorities in Moshi rural district, northern Tanzania

    Makundi, E. A., Manongi, R., Mushi, A. K., Alilio, M. S., Theander, Thor Grundtvig, Rønn, A. M. & Bygbjerg, Ib Christian, 2005, In: Tanzania Health Research Bulletin. 7, 3, p. 133-41 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Use of community owned resource persons (CORPs) in management of malaria in villages with different transmission intensity, North eastern Tanzania [MIM-BM-37562]

    Mmbando, B., Lusingu, J., Vestergaard, L., Gesase, S., Minja, D., Minja, S., Malecela, E., Kitua, A., Lemnge, M. & Theander, Thor Grundtvig, 2005, In: Acta Tropica.

    Research output: Contribution to journal › Journal article › Research

  7. 2004
  8. Published

    Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes

    Jensen, Anja Ramstedt, Magistrado, P., Sharp, S., Joergensen, L., Lavstsen, Thomas, Chiucchiuini, A., Salanti, Ali, Vestergaard, L. S., Lusingu, J. P., Hermsen, R., Sauerwein, R., Christensen, J., Nielsen, Morten Agertoug, Hviid, Lars, Sutherland, C., Staalsoe, T. & Theander, Thor Grundtvig, 2004, In: Journal of Experimental Medicine. 199, 9, p. 1179-90 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Allelic polymorphisms in the repeat and promoter regions of the interleukin-4 gene and malaria severity in Ghanaian children

    Gyan, B. A., Goka, B., Cvetkovic, J. T., Kurtzhals, Jørgen, Adabayeri, V., Perlmann, H., Lefvert, A., Akanmori, B. D. & Troye-Blomberg, M., 2004, In: Clinical and Experimental Immunology. 138, 1, p. 145-50 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Analysis of IgG with specificity for variant surface antigens expressed by placental Plasmodium falciparum isolates

    Khattab, A., Reinhardt, C., Staalsoe, T., Fievet, N., Kremsner, P. G., Deloron, P., Hviid, Lars & Klinkert, M., 2004, In: Malaria Journal. 3, p. 21

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Antibodies from malaria-exposed pregnant women recognize trypsin resistant epitopes on the surface of Plasmodium falciparum-infected erythrocytes selected for adhesion to chondroitin sulphate A

    Sharling, L., Enevold, A., Sowa, K. M. P., Staalsoe, T. & Arnot, D. E., 2004, In: Malaria Journal. 3, p. 31

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Antibodies to the N-terminal block 2 of Plasmodium falciparum merozoite surface protein 1 are associated with protection against clinical malaria

    Cavanagh, D. R., Dodoo, D., Hviid, Lars, Kurtzhals, Jørgen, Theander, Thor Grundtvig, Akanmori, B. D., Polley, S., Conway, D. J., Koram, K. & McBride, J. S., 2004, In: Infection and Immunity. 72, 11, p. 6492-502 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Are multilateral malaria research and control programs the most successful? Lessons from the past 100 years in Africa

    Alilio, M. S., Bygbjerg, Ib Christian & Breman, J. G., 2004, In: American Journal of Tropical Medicine and Hygiene. 71, 2 Suppl, p. 268-78 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Atovaquone-proguanil (Malarone): an effective treatment for uncomplicated Plasmodium falciparum malaria in travellers from Denmark

    Thybo, S., Gjorup, I., Ronn, A. M., Meyrowitsch, Dan Wolf, Kronborg, G. & Bygbjerg, I. C., 2004, In: Journal of Travel Medicine. 11, p. 220-223

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Compounds useful in the diagnosis and treatment of pregnancy-associated malaria

    Theander, Thor Grundtvig, Salanti, Ali, Hviid, Lars, Staalsø, Trine, Jensen, Anja Ramstedt, Lavstsen, Thomas & Dahlbäck, M., 2004, Patent No. WO2004067559 A1, Priority date 27 Jan 2003, Priority No. WO2004067559 A1

    Research output: Patent

  16. Published

    Efficacy of chloroquine, amodiaquine, sulphadoxine-pyrimethamine and combination therapy with artesunate in Mozambican children with non-complicated malaria

    Abacassamo, F., Enosse, S., Aponte, J. J., Gómez-Olivé, F. X., Quintó, L., Mabunda, S., Barreto, A., Magnussen, Pascal, Rønn, A. M., Thompson, R. & Alonso, P. L., 2004, In: Tropical Medicine & International Health. 9, 2, p. 200-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Eleven years of malaria surveillance in a Sudanese village highlights unexpected variation in individual disease susceptibility and outbreak severity

    Creasey, A., Giha, H., Hamad, A. A., El Hassan, I. M., Theander, Thor Grundtvig & Arnot, D. E., 2004, In: Parasitology. 129, Pt 3, p. 263-71 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Evidence for the involvement of VAR2CSA in pregnancy-associated malaria

    Salanti, Ali, Dahlbäck, M., Turner, Louise, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Magistrado, P., Jensen, Anja Ramstedt, Lavstsen, Thomas, Ofori, M. F., Marsh, K., Hviid, Lars & Theander, Thor Grundtvig, 2004, In: Journal of Experimental Medicine. 200, 9, p. 1197-203 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Geographical and temporal conservation of antibody recognition of Plasmodium falciparum variant surface antigens

    Nielsen, Morten Agertoug, Vestergaard, L. S., Lusingu, J., Kurtzhals, Jørgen, Giha, H. A., Grevstad, B., Goka, B. Q., Lemnge, M. M., Jensen, J. B., Akanmori, B. D., Theander, Thor Grundtvig, Staalsoe, T. & Hviid, Lars, 2004, In: Infection and Immunity. 72, 6, p. 3531-5 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Homology building as a means to define antigenic epitopes on dihydrofolate reductase (DHFR) from Plasmodium falciparum

    Alifrangis, Michael, Christensen, I. T., Jørgensen, Flemming Steen, Rønn, A. M., Weng, J. E., Chen, M., Bygbjerg, Ib Christian, Sirawaraporn, W., Palarasah, Y. & Koch, C., 2004, In: Malaria Journal. 3, p. 16

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Intermittent preventive sulfadoxine-pyrimethamine treatment of primigravidae reduces levels of plasma immunoglobulin G, which protects against pregnancy-associated Plasmodium falciparum malaria

    Staalsoe, T., Shulman, C. E., Dorman, E. K., Kawuondo, K., Marsh, K. & Hviid, Lars, 2004, In: Infection and Immunity. 72, 9, p. 5027-30 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Malaria control at the district level in Africa: the case of the muheza district in northeastern Tanzania

    Alilio, M. S., Kitua, A., Njunwa, K., Medina, M., Rønn, A. M., Mhina, J., Msuya, F., Mahundi, J., Depinay, J. M., Whyte, Susan Reynolds, Krasnik, Allan & Bygbjerg, Ib Christian, 2004, In: American Journal of Tropical Medicine and Hygiene. 71, 2 Suppl, p. 205-13 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Malaria immunity in infants: a special case of a general phenomenon?

    Hviid, Lars & Staalsoe, T., 2004, In: Trends in Parasitology. 20, 2, p. 66-72 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Malaria morbidity and immunity among residents of villages with different Plasmodium falciparum transmission intensity in North-Eastern Tanzania

    Lusingu, J. P. A., Vestergaard, L. S., Mmbando, B. P., Drakeley, C. J., Jones, C., Akida, J., Savaeli, Z. X., Kitua, A. Y., Lemnge, M. M. & Theander, Thor Grundtvig, 2004, In: Malaria Journal. 3, p. 26

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Molecular cloning of a K+ channel from the malaria parasite Plasmodium falciparum

    Ellekvist, P., Ricke, C. H., Litman, Thomas, Salanti, Ali, Colding, H., Zeuthen, Thomas & Klærke, Dan Arne, 2004, In: Biochemical and Biophysical Research Communications. 318, 2, p. 477-84 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Screening for mutations related to atovaquone/proguanil resistance in treatment failures and other imported isolates of Plasmodium falciparum in Europe

    Wichmann, O., Muehlberger, N., Jelinek, T., Alifrangis, M., Peyerl-Hoffmann, G., Muhlen, M., Grobusch, M. P., Gascon, J., Matteelli, A., Laferl, H., Bisoffi, Z., Ehrhardt, S., Cuadros, J., Hatz, C., Gjorup, I., McWhinney, P., Beran, J., da Cunha, S., Schulze, M., Kollaritsch, H. & 4 others, Kern, P., Fry, G., Richter, J. & European Network on Surveillance of Imported Infectious Diseases, E. N. O. S. O. I. I. D., 2004, In: Journal of Infectious Diseases. 190, 9, p. 1541-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    The immuno-epidemiology of pregnancy-associated Plasmodium falciparum malaria: a variant surface antigen-specific perspective

    Hviid, Lars, 2004, In: Parasite Immunology. 26, 11-12, p. 477-86 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Unchanged acetylation of isoniazid by alcohol intake

    Wilcke, Jon Torgny Rostrup, Døssing, M., Angelo, H. R., Askgaard, D., Rønn, A. & Christensen, H. R., 2004, In: International Journal of Tuberculosis and Lung Disease. 8, 11, p. 1373-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Variant surface antigen-specific IgG and protection against clinical consequences of pregnancy-associated Plasmodium falciparum malaria

    Staalsoe, T., Shulman, C. E., Bulmer, J. N., Kawuondo, K., Marsh, K. & Hviid, Lars, 2004, In: Lancet. 363, 9405, p. 283-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Variant surface antigens, virulence genes and the pathogenesis of malaria

    Deitsch, K. W. & Hviid, Lars, 2004, In: Trends in Parasitology. 20, 12, p. 562-6 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 2003
  32. Published

    Prediction of Plasmodium falciparum resistance to sulfadoxine/ pyrimethamine in vivo by mutations in the dihydrofolate reductase and dihydropteroate synthetase genes: A comparative study between sites of differing endemicity

    Alifrangis, Michael, Enosse, S., Khalil, I. F., Tarimo, D. S., Lemnge, M. M., Thompson, R., Bygbjerg, Ib Christian & Rønn, A. M., 1 Dec 2003, In: American Journal of Tropical Medicine and Hygiene. 69, 6, p. 601-606 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    In vitro selection of Plasmodium falciparum 3D7 for expression of variant surface antigens associated with severe malaria in African children

    Staalsoe, T., Nielsen, Morten Agertoug, Vestergaard, L. S., Jensen, Anja Ramstedt, Theander, Thor Grundtvig & Hviid, Lars, 2003, In: Parasite Immunology. 25, 8-9, p. 421-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Atovaquone/proguanil resistance in Africa: a case report

    David, K. P., Alifrangis, Michael, Salanti, Ali, Vestergaard, L. S., Rønn, A. & Bygbjerg, Ib Christian, 2003, In: Scandinavian Journal of Infectious Diseases. 35, 11-12, p. 897-8 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    CCR3 expression induced by IL-2 and IL-4 functioning as a death receptor for B cells

    Jinquan, T., Jacobi, H. H., Jing, C., Millner, A., Sten, E., Hviid, Lars, Anting, L., Ryder, L. P., Glue, C., Skov, P. S., Jarman, E., Lamberth, K., Malling, H. & Poulsen, Lars K., 2003, In: Journal of Immunology. 171, 4, p. 1722-31 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Comparison of chloroquine with Quinimax(R) in the treatment of cerebral malaria in Ghanaian children

    Goka, B. Q., Rodrigues, O. R., Adjei, G. O., Quarshie, B., Akanmori, B. D., Kurtzhals, Jørgen & Neequaye, J., 2003, In: Ghana Medical Journal. 37, p. 110-116 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Different mutation patterns of atovaquone resistance to Plasmodium falciparum in vitro and in vivo: rapid detection of codon 268 polymorphisms in the cytochrome b as potential in vivo resistance marker

    Schwöbel, B., Alifrangis, Michael, Salanti, Ali & Jelinek, T., 2003, In: Malaria Journal. 2, p. 5

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Dihydrofolate reductase and dihydropteroate synthase genotypes associated with in vitro resistance of Plasmodium falciparum to pyrimethamine, trimethoprim, sulfadoxine, and sulfamethoxazole

    Khalil, I., Rønn, A. M., Alifrangis, Michael, Gabar, H. A., Satti, G. M. H. & Bygbjerg, Ib Christian, 2003, In: American Journal of Tropical Medicine and Hygiene. 68, 5, p. 586-9 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Effect of intermittent treatment with amodiaquine on anaemia and malarial fevers in infants in Tanzania: a randomised placebo-controlled trial

    Massaga, J. J., Kitua, A. Y., Lemnge, M. M., Akida, J. A., Malle, L. N., Rønn, A. M., Theander, Thor Grundtvig & Bygbjerg, Ib Christian, 2003, In: Lancet. 361, 9372, p. 1853-60 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Expression of variant surface antigens by Plasmodium falciparum parasites in the peripheral blood of clinically immune pregnant women indicates ongoing placental infection

    Ofori, M. F., Staalsoe, T., Bam, V., Lundquist, M., David, K. P., Browne, E. N. L., Akanmori, B. D. & Hviid, Lars, 2003, In: Infection and Immunity. 71, 3, p. 1584-6 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    High circulating levels of tumor necrosis factor-alpha in centenarians are not associated with increased production in T lymphocytes

    Sandmand, M., Bruunsgaard, H., Kemp, K., Andersen-Ranberg, K., Schroll, M. & Jeune, B., 2003, In: Gerontology. 49, 3, p. 155-60 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Increasing prevalence of wildtypes in the dihydrofolate reductase gene of Plasmodium falciparum in an area with high levels of sulfadoxine/pyrimethamine resistance after introduction of treated bed nets

    Alifrangis, Michael, Lemnge, M. M., Rønn, A. M., Segeja, M. D., Magesa, S. M., Khalil, I. F. & Bygbjerg, Ib Christian, 2003, In: American Journal of Tropical Medicine and Hygiene. 69, 3, p. 238-43 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malaria

    Jensen, Anja Ramstedt, Zornig, H. D., Buhmann, Cæcilie Christine Böck, Salanti, Ali, Koram, K. A., Riley, E. M., Theander, Thor Grundtvig, Hviid, Lars & Staalsoe, T., 2003, In: Infection and Immunity. 71, 7, p. 4193-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Mannose-binding lectin is a disease modifier in clinical malaria and may function as opsonin for Plasmodium falciparum-infected erythrocytes

    Garred, Peter, Nielsen, Morten Agertoug, Kurtzhals, Jørgen, Malhotra, R., Madsen, H. O., Goka, B. Q., Akanmori, B. D., Sim, R. B. & Hviid, Lars, 2003, In: Infection and Immunity. 71, 9, p. 5245-53 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Maternally transmitted antibodies to pregnancy-associated variant antigens on the surface of erythrocytes infected with Plasmodium falciparum: relation to child susceptibility to malaria

    Cot, M., Le Hesran, J. Y., Staalsoe, T., Fievet, N., Hviid, Lars & Deloron, P., 2003, In: American Journal of Epidemiology. 157, 3, p. 203-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Molecular surveillance of the antifolate-resistant mutation I164L in imported African isolates of Plasmodium falciparum in Europe: sentinel data from TropNetEurop

    Wichmann, O., Jelinek, T., Peyerl-Hoffmann, G., Mühlberger, N., Grobusch, M. P., Gascon, J., Matteelli, A., Hatz, C., Laferl, H., Schulze, M., Burchard, G., da Cunha, S., Beran, J., McWhinney, P., Kollaritsch, H., Kern, P., Cuadros, J., Alifrangis, Michael, Gjørup, I. & European Network on Surveillance of Imported Infectious Diseases (TropNetEurop), E. N. O. S. O. I. I. D. (., 2003, In: Malaria Journal. 2, p. 17

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Nonspecific immunoglobulin M binding and chondroitin sulfate A binding are linked phenotypes of Plasmodium falciparum isolates implicated in malaria during pregnancy

    Creasey, A. M., Staalsoe, T., Raza, A., Arnot, D. E. & Rowe, J. A., 2003, In: Infection and Immunity. 71, 8, p. 4767-71 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Prediction of Plasmodium falciparum resistance to sulfadoxine/pyrimethamine in vivo by mutations in the dihydrofolate reductase and dihydropteroate synthetase genes: a comparative study between sites of differing endemicity

    Alifrangis, Michael, Enosse, S., Khalil, I. F., Tarimo, D. S., Lemnge, M. M., Thompson, R., Bygbjerg, Ib Christian & Rønn, A. M., 2003, In: American Journal of Tropical Medicine and Hygiene. 69, 6, p. 601-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria

    Salanti, Ali, Staalsoe, T., Lavstsen, Thomas, Jensen, Anja Ramstedt, Sowa, M. P. K., Arnot, D. E., Hviid, Lars & Theander, Thor Grundtvig, 2003, In: Molecular Microbiology. 49, 1, p. 179-91 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Severe malaria in west African children

    Kurtzhals, Jørgen, Helleberg, M., Goka, B. Q. & Akanmori, B. D., 2003, In: Lancet. 361, 9366, p. 1393

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Specificity and cross-reactivity of Plasmodium falciparum variant surface antigen-specific antibody responses

    Hviid, Lars, Staalsoe, T., Nielsen, Morten Agertoug & Theander, Thor Grundtvig, 2003, In: Infection and Immunity. 71, 4, p. 2296

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Sub-grouping of Plasmodium falciparum 3D7 var genes based on sequence analysis of coding and non-coding regions

    Lavstsen, Thomas, Salanti, Ali, Jensen, Anja Ramstedt, Arnot, D. E. & Theander, Thor Grundtvig, 2003, In: Malaria Journal. 2, p. 27

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. 2002
  54. Published

    Prevalence and morbidity of urinary schistosomiasis among schoolchildren in the Mwera division of Pangani district, Tanzania, 30 months after the last round of annual, selective treatments

    Magnussen, Pascal, Ndawi, B., Sheshe, A. K., Byskov, J. & Mbwana, K., Dec 2002, In: Pathogens and Global Health. 96, 8, p. 843-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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