TARGETS team

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  1. 2019
  2. Published

    Gαs-coupled receptor signaling and sleep regulate integrin activation of human antigen-specific T cells

    Dimitrov, S., Lange, T., Gouttefangeas, C., Jensen, Anja Ramstedt, Szczepanski, M., Lehnnolz, J., Soekadar, S., Rammensee, H., Born, J. & Besedovsky, L., 2019, In: The Journal of Experimental Medicine. 216, 3, p. 517-526 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2018
  4. Published

    A vaccine targeted specifically to prevent cerebral malaria - is there hope?

    Hviid, Lars, Lavstsen, Thomas & Jensen, Anja Ramstedt, Jul 2018, In: Expert Review of Vaccines. 17, 7, p. 565-567 3 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  5. Published

    A specific PfEMP1 is expressed in P. falciparum sporozoites and plays a role in hepatocyte infection

    Zanghì, G., Vembar, S. S., Baumgarten, S., Ding, S., Guizetti, J., Bryant, J. M., Mattei, D., Jensen, A. T. R., Rénia, L., Goh, Y. S., Sauerwein, R., Hermsen, C. C., Franetich, J-F., Bordessoulles, M., Silvie, O., Soulard, V., Scatton, O., Chen, P., Mecheri, S., Mazier, D. & 1 others, Scherf, A., 2018, In: Cell Reports. 22, 11, p. 2951-2963 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Activated integrins identify functional antigen-specific CD8 T cells within minutes after antigen stimulation

    Dimitrov, S., Gouttefangeas, C., Besedovsky, L., Jensen, Anja Ramstedt, Chandran, P. A., Rusch, E., Businger, R., Schindler, M., Lange, T., Born, J. & Rammensee, H., 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 24, p. E5536-E5545

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Blood outgrowth endothelial cells (BOECs) as a novel tool for studying adhesion of Plasmodium falciparum-infected erythrocytes

    Ecklu-Mensah, G., Olsen, Rebecca Wendelboe, Bengtsson, A., Ofori, M. F., Hviid, Lars, Jensen, Anja Ramstedt & Adams, Yvonne, 2018, In: PLoS ONE. 13, 10, 12 p., e0204177.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Natural and vaccine-induced acquisition of cross-reactive IgG inhibiting ICAM-1-specific binding of a Plasmodium falciparum PfEMP1 subtype associated specifically with cerebral malaria

    Olsen, Rebecca Wendelboe, Ecklu-Mensah, G., Bengtsson, A., Ofori, M. F., Lusingu, J. P. A., Castberg, F. C., Hviid, Lars, Adams, Yvonne & Jensen, Anja Ramstedt, 2018, In: Infection and Immunity. 86, 4, 17 p., e00622-17.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Shed EBA-175 mediates red blood cell clustering that enhances malaria parasite growth and enables immune evasion

    Paing, M. M., Salinas, N. D., Adams, Yvonne, Oksman, A., Jensen, Anja Ramstedt, Goldberg, D. E. & Tolia, N. H., 2018, In: eLife. 7, 18 p., e43224.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2017
  11. Published

    Structure-guided identification of a family of dual receptor-binding PfEMP1 that is associated with cerebral malaria

    Lennartz, F., Adams, Y., Bengtsson, A., Olsen, R. W., Turner, L., Ndam, N. T., Ecklu-Mensah, G. D., Moussiliou, A., Ofori, M. F., Gamain, B., Lusingu, J. P., Petersen, J. E. V., Wang, C. W., Nunes-Silva, S., Jespersen, J. S., Lau, C. K. Y., Theander, T. G., Lavstsen, T., Hviid, L., Higgins, M. K. & 1 others, Jensen, Anja Ramstedt, 8 Mar 2017, In: Cell Host & Microbe. 21, 3, p. 403-414 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Parasites causing cerebral falciparum malaria bind multiple endothelial receptors and express EPCR and ICAM-1-binding PfEMP1

    Tuikue Ndam, N., Moussiliou, A., Lavstsen, Thomas, Kamaliddin, C., Jensen, Anja Ramstedt, Mama, A., Tahar, R., Wang, Christian William, Jespersen, Jakob Schmidt, Alao, J. M., Gamain, B., Theander, Thor Grundtvig & Deloron, P., 2017, In: The Journal of Infectious Diseases. 215, 12, p. 1918-1925 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. 2016
  14. Published

    Characterizing the impact of sustained sulfadoxine/pyrimethamine use upon the Plasmodium falciparum population in Malawi

    Ravenhall, M., Benavente, E. D., Mipando, M., Jensen, Anja Ramstedt, Sutherland, C. J., Roper, C., Sepúlveda, N., Kwiatkowski, D. P., Montgomery, J., Phiri, K. S., Terlouw, A., Craig, A., Campino, S., Ocholla, H. & Clark, T. G., 29 Nov 2016, In: Malaria Journal. 15, 11 p., 575.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. 2015
  16. Published

    PfEMP1 – a parasite protein family of key importance in Plasmodium falciparum malaria immunity and pathogenesis

    Hviid, Lars & Jensen, Anja Ramstedt, Apr 2015, Advances in Parasitology. Rollinson, D. & Stothard, J. R. (eds.). Vol. 88. p. 51-84 34 p. (Advances in Parasitology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  17. Published

    Mapping the binding site of a cross-reactive Plasmodium falciparum PfEMP1 monoclonal antibody inhibitory of ICAM-1 binding

    Lennartz, F., Bengtsson, A., Olsen, Rebecca Wendelboe, Joergensen, L., Brown, A., Remy, L., Man, P., Forest, E., Barfod, Lea Klingenberg, Adams, Yvonne, Higgins, M. K. & Jensen, Anja Ramstedt, 2015, In: Journal of immunology (Baltimore, Md. : 1950). 195, 7, p. 3273-83 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. 2014
  19. Published

    Whole-Genome Scans Provide Evidence of Adaptive Evolution in Malawian Plasmodium falciparum Isolates

    Ocholla, H., Preston, M. D., Mipando, M., Jensen, A. T. R., Campino, S., MacInnis, B., Alcock, D., Terlouw, A., Zongo, I., Oudraogo, J-B., Djimde, A. A., Assefa, S., Doumbo, O. K., Borrmann, S., Nzila, A., Marsh, K., Fairhurst, R. M., Nosten, F., Anderson, T. J. C., Kwiatkowski, D. P. & 3 others, Craig, A., Clark, T. G. & Montgomery, J., 19 Jun 2014, In: The Journal of Infectious Diseases. 210, 12, p. 1991-2000 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Rosetting Plasmodium falciparum-infected erythrocytes bind to human brain microvascular endothelial cells in vitro, demonstrating a dual adhesion phenotype mediated by distinct P. falciparum erythrocyte membrane protein 1 domains

    Adams, Yvonne, Kuhnrae, P., Higgins, M. K., Ghumra, A. & Rowe, J. A., Mar 2014, In: Infection and Immunity. 82, 3, p. 949-959 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    An analysis of the binding characteristics of a panel of recently selected ICAM-1 binding Plasmodium falciparum patient isolates

    Madkhali, A. M., Alkurbi, M. O., Szestak, T., Bengtsson, A., Patil, P. R., Wu, Y., Alharthi, S., Jensen, Anja Ramstedt, Pleass, R. & Craig, A. G., 2014, In: PLOS ONE. 9, 10, 8 p., e111518.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria

    Zhang, Q., Siegel, T. N., Martins, R. M., Wang, F., Cao, J., Gao, Q., Cheng, X., Jiang, L., Hon, C., Scheidig-Benatar, C., Sakamoto, H., Turner, Louise, Jensen, Anja Ramstedt, Claes, A., Guizetti, J., Malmquist, N. A. & Scherf, A., 2014, In: Nature. 531, p. 431-435

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 2013
  24. Published

    The Effect of Anti-Rosetting Agents against Malaria Parasites under Physiological Flow Conditions

    Adams, Yvonne & Rowe, J. A., 16 Sep 2013, In: PLoS ONE. 8, 9, e73999.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    A Method for Positive and Negative Selection of Plasmodium falciparum Platelet-Mediated Clumping Parasites and Investigation of the Role of CD36

    Arman, M., Adams, Yvonne, Lindergard, G. & Rowe, J. A., 6 Feb 2013, In: PLoS ONE. 8, 2, e55453.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    A Novel Domain Cassette Identifies Plasmodium falciparum PfEMP1 Proteins Binding ICAM-1 and Is a Target of Cross-Reactive, Adhesion-Inhibitory Antibodies

    Bengtsson, A., Joergensen, L., Rask, T. S., Olsen, R. W., Andersen, M. A., Turner, Louise, Theander, Thor Grundtvig, Hviid, Lars, Higgins, M. K., Craig, A., Brown, A. & Jensen, Anja Ramstedt, 2013, In: Journal of Immunology. 190, 1, p. 240-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Transfected HEK293 Cells Expressing Functional Recombinant Intercellular Adhesion Molecule 1 (ICAM-1) - A Receptor Associated with Severe Plasmodium falciparum Malaria

    Bengtsson, A., Joergensen, L., Barbati, Z. R., Craig, A., Hviid, Lars & Jensen, Anja Ramstedt, 2013, In: PLOS ONE. 8, 7, p. e69999

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. 2012
  29. Published

    Induction of strain-transcending antibodies against group A PfEMP1 surface antigens from virulent malaria parasites

    Ghumra, A., Semblat, J. P., Ataide, R., Kifude, C., Adams, Yvonne, Claessens, A., Anong, D. N., Bull, P. C., Fennell, C., Arman, M., Amambua-Ngwa, A., Walther, M., Conway, D. J., Kassambara, L., Doumbo, O. K., Raza, A. & Rowe, J. A., Apr 2012, In: PLoS Pathogens. 8, 4, e1002665.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Analysis of Single-cell Gene Transcription by RNA Fluorescent In Situ Hybridization (FISH)

    Ronander, E., Bengtsson, D. C., Joergensen, L., Jensen, Anja Ramstedt & Arnot, D. E., 2012, In: Journal of Visualized Experiments. 68

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 2011
  32. Published

    Antigenic variation and the genetics and epigenetics of the PfEMP1 erythrocyte surface antigens in Plasmodium falciparum malaria

    Arnot, D. E. & Jensen, Anja Ramstedt, 2011, In: Advances in Applied Microbiology. 74, p. 77-96 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. 2010
  34. Published

    Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian children

    Cham, G. K. K., Turner, Louise, Kurtis, J. D., Mutabingwa, T., Fried, M., Jensen, Anja Ramstedt, Lavstsen, Thomas, Hviid, Lars, Duffy, P. E. & Theander, Thor Grundtvig, 2010, In: Infection and Immunity. 78, 11, p. 4653-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Insect cells are superior to Escherichia coli in producing malaria proteins inducing IgG targeting PfEMP1 on infected erythrocytes

    Victor, M. E., Bengtsson, A., Andersen, G., Bengtsson, D., Lusingu, J. P., Vestergaard, L. S., Arnot, D. E., Theander, Thor Grundtvig, Joergensen, L. & Jensen, Anja Ramstedt, 2010, In: Malaria Journal. 9, p. 325

    Research output: Contribution to journal › Journal article › Research › peer-review

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