Standard
Differential patterns of human immunoglobulin G subclass responses to distinct regions of a single protein, the merozoite surface protein 1 of Plasmodium falciparum. / Cavanagh, D R; Dobaño, C; Elhassan, I M; Marsh, K; Elhassan, A; Hviid, L; Khalil, E A; Theander, T G; Arnot, D E; McBride, J S.
In:
Infection and Immunity, Vol. 69, No. 2, 2001, p. 1207-11.
Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
Cavanagh, DR, Dobaño, C, Elhassan, IM, Marsh, K, Elhassan, A
, Hviid, L, Khalil, EA
, Theander, TG, Arnot, DE & McBride, JS 2001, '
Differential patterns of human immunoglobulin G subclass responses to distinct regions of a single protein, the merozoite surface protein 1 of Plasmodium falciparum',
Infection and Immunity, vol. 69, no. 2, pp. 1207-11.
https://doi.org/10.1128/IAI.69.2.1207-1211.2001APA
Cavanagh, D. R., Dobaño, C., Elhassan, I. M., Marsh, K., Elhassan, A.
, Hviid, L., Khalil, E. A.
, Theander, T. G., Arnot, D. E., & McBride, J. S. (2001).
Differential patterns of human immunoglobulin G subclass responses to distinct regions of a single protein, the merozoite surface protein 1 of Plasmodium falciparum.
Infection and Immunity,
69(2), 1207-11.
https://doi.org/10.1128/IAI.69.2.1207-1211.2001Vancouver
Cavanagh DR, Dobaño C, Elhassan IM, Marsh K, Elhassan A
, Hviid L et al.
Differential patterns of human immunoglobulin G subclass responses to distinct regions of a single protein, the merozoite surface protein 1 of Plasmodium falciparum.
Infection and Immunity. 2001;69(2):1207-11.
https://doi.org/10.1128/IAI.69.2.1207-1211.2001Author
Cavanagh, D R ; Dobaño, C ; Elhassan, I M ; Marsh, K ; Elhassan, A ; Hviid, L ; Khalil, E A ; Theander, T G ; Arnot, D E ; McBride, J S. / Differential patterns of human immunoglobulin G subclass responses to distinct regions of a single protein, the merozoite surface protein 1 of Plasmodium falciparum. In: Infection and Immunity. 2001 ; Vol. 69, No. 2. pp. 1207-11.
Bibtex
@article{b1147c40a03a11dd86a6000ea68e967b,
title = "Differential patterns of human immunoglobulin G subclass responses to distinct regions of a single protein, the merozoite surface protein 1 of Plasmodium falciparum",
abstract = "Comparisons of immunoglobulin G (IgG) subclass responses to the major polymorphic region and to a conserved region of MSP-1 in three cohorts of African villagers exposed to Plasmodium falciparum revealed that responses to Block 2 are predominantly IgG3 whereas antibodies to MSP-1(19) are mainly IgG1. The striking dominance of IgG3 to Block 2 may explain the short duration of this response and also the requirement for continuous stimulation by malaria infection to maintain clinical immunity.",
author = "Cavanagh, {D R} and C Doba{\~n}o and Elhassan, {I M} and K Marsh and A Elhassan and L Hviid and Khalil, {E A} and Theander, {T G} and Arnot, {D E} and McBride, {J S}",
note = "Keywords: Adolescent; Adult; Aged; Animals; Antibodies, Protozoan; Child; Child, Preschool; Humans; Immunoglobulin G; Infant; Merozoite Surface Protein 1; Middle Aged; Peptide Fragments; Plasmodium falciparum",
year = "2001",
doi = "10.1128/IAI.69.2.1207-1211.2001",
language = "English",
volume = "69",
pages = "1207--11",
journal = "Infection and Immunity",
issn = "0019-9567",
publisher = "American Society for Microbiology",
number = "2",
}
RIS
TY - JOUR
T1 - Differential patterns of human immunoglobulin G subclass responses to distinct regions of a single protein, the merozoite surface protein 1 of Plasmodium falciparum
AU - Cavanagh, D R
AU - Dobaño, C
AU - Elhassan, I M
AU - Marsh, K
AU - Elhassan, A
AU - Hviid, L
AU - Khalil, E A
AU - Theander, T G
AU - Arnot, D E
AU - McBride, J S
N1 - Keywords: Adolescent; Adult; Aged; Animals; Antibodies, Protozoan; Child; Child, Preschool; Humans; Immunoglobulin G; Infant; Merozoite Surface Protein 1; Middle Aged; Peptide Fragments; Plasmodium falciparum
PY - 2001
Y1 - 2001
N2 - Comparisons of immunoglobulin G (IgG) subclass responses to the major polymorphic region and to a conserved region of MSP-1 in three cohorts of African villagers exposed to Plasmodium falciparum revealed that responses to Block 2 are predominantly IgG3 whereas antibodies to MSP-1(19) are mainly IgG1. The striking dominance of IgG3 to Block 2 may explain the short duration of this response and also the requirement for continuous stimulation by malaria infection to maintain clinical immunity.
AB - Comparisons of immunoglobulin G (IgG) subclass responses to the major polymorphic region and to a conserved region of MSP-1 in three cohorts of African villagers exposed to Plasmodium falciparum revealed that responses to Block 2 are predominantly IgG3 whereas antibodies to MSP-1(19) are mainly IgG1. The striking dominance of IgG3 to Block 2 may explain the short duration of this response and also the requirement for continuous stimulation by malaria infection to maintain clinical immunity.
U2 - 10.1128/IAI.69.2.1207-1211.2001
DO - 10.1128/IAI.69.2.1207-1211.2001
M3 - Journal article
C2 - 11160024
VL - 69
SP - 1207
EP - 1211
JO - Infection and Immunity
JF - Infection and Immunity
SN - 0019-9567
IS - 2
ER -
