Morten Agertoug Nielsen

Morten Agertoug Nielsen

Professor

Member of:

  • VAR2CSA team


  1. 2015
  2. Published

    The Influence of Sub-Unit Composition and Expression System on the Functional Antibody Response in the Development of a VAR2CSA Based Plasmodium falciparum Placental Malaria Vaccine

    Nielsen, M. A., dos Santos Marques Resende, M., de Jongh, W. A., Ditlev, S. B., Mordmüller, B., Houard, S., Ndam, N. T., Agerbæk, M. Ø., Jensen, M. H., Massougbodji, A., Issifou, S., Strøbæk, A., Poulsen, L., Leroy, O., Kremsner, P. G., Chippaux, J-P., Luty, A. J. F., Deloron, P., Theander, T. G., Dyring, C. & 1 others, Salanti, Ali, 2015, In: PloS one. 10, 9, 12 p., e0135406.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2014
  4. Published

    Utilizing nanobody technology to target non-immunodominant domains of VAR2CSA

    Ditlev, S. B., Florea, R., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Magez, S., Boeuf, P. & Salanti, Ali, 21 Jan 2014, In: PLOS ONE. 9, 1, p. e84981

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2013
  6. Published

    Differential adhesion-inhibitory patterns of antibodies raised against two major variants of the NTS-DBL2X region of VAR2CSA

    Doritchamou, J., Bigey, P., Nielsen, Morten Agertoug, Gnidehou, S., Ezinmegnon, S., Burgain, A., Massougbodji, A., Deloron, P., Salanti, Ali & Ndam, N. T., 23 Sep 2013, In: Vaccine. 31, 41, p. 4516-22 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Severe malaria is associated with parasite binding to endothelial protein C receptor

    Turner, Louise, Lavstsen, Thomas, Berger, S. S., Wang, Christian William, Petersen, J. E. V., Avril, M., Brazier, A. J., Freeth, J., Jespersen, Jakob Schmidt, Nielsen, Morten Agertoug, Magistrado, P., Lusingu, J., Smith, J. D., Higgins, M. K. & Theander, Thor Grundtvig, 27 Jun 2013, In: Nature. 498, 7455, p. 502-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Multilaboratory approach to preclinical evaluation of vaccine immunogens for placental malaria

    Fried, M., Avril, M., Chaturvedi, R., Fernandez, P., Lograsso, J., Narum, D., Nielsen, Morten Agertoug, Oleinikov, A. V., Resende, M., Salanti, Ali, Saveria, T., Williamson, K., Dicko, A., Scherf, A., Smith, J. D., Theander, Thor Grundtvig & Duffy, P. E., 2013, In: Infect Immun. 81, 2, p. 487-95 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Plasmodium falciparum Expressing Domain Cassette 5 Type PfEMP1 (DC5-PfEMP1) Bind PECAM1

    Berger, S. S., Turner, Louise, Wang, Christian William, Petersen, J. E. V., Kraft, M., Lusingu, J. P. A., Mmbando, B., Marquard, A. M., Bengtsson, D. B. A. C., Hviid, Lars, Nielsen, Morten Agertoug, Theander, Thor Grundtvig & Lavstsen, Thomas, 2013, In: PloS one. 8, 7, p. e69117

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2012
  11. Published

    Identification and characterization of B-cell epitopes in the DBL4e domain of VAR2CSA

    Ditlev, S. B., Nielsen, Morten Agertoug, Resende, M., Agerbæk, Mette Ørskov, Pinto, V. V., Andersen, P. H., Magistrado, P., Lusingu, J., Dahlbäck, M., Theander, Thor Grundtvig & Salanti, Ali, 2012, In: P L o S One. 7, 9, p. e43663

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Marchantin A, a macrocyclic bisbibenzyl ether, isolated from the liverwort Marchantia polymorpha, inhibits protozoal growth in vitro

    Jensen, S., Omarsdottir, S., Bwalya, A. G., Nielsen, Morten Agertoug, Tasdemir, D. & Olafsdottir, E. S., 2012, In: Phytomedicine. 19, 13, p. 1191-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Structural and functional insight into how the Plasmodium falciparum VAR2CSA protein mediates binding to chondroitin sulfate A in placental malaria

    Clausen, Thomas Mandel, Christoffersen, S., Dahlbäck, M., Langkilde, Annette Eva, Jensen, K. E., Resende, M., Agerbæk, Mette Ørskov, Andersen, D., Berisha, B., Ditlev, S. B., Pinto, V. V., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Larsen, Sine & Salanti, Ali, 2012, In: Journal of Biological Chemistry. 287, 28, p. 23332-45 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The effect of adjuvants on the immune response induced by a DBL4e-ID4 VAR2CSA based Plasmodium falciparum vaccine against placental malaria

    Pinto, V. V., Salanti, Ali, Joergensen, L. M., Dahlbäck, M., Resende, M., Ditlev, S. B., Agger, E. M., Arnot, D. E., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2012, In: Vaccine. 30, 3, p. 572-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2011
  16. Published

    Differential induction of functional IgG using the Plasmodium falciparum placental malaria vaccine candidate VAR2CSA

    Pinto, V. V., Ditlev, S. B., Jensen, K. E., Resende, M., Dahlbäck, M., Andersen, G., Andersen, P., Theander, Thor Grundtvig, Salanti, Ali & Nielsen, Morten Agertoug, 1 Jan 2011, In: P L o S One. 6, 3, p. e17942

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    High efficacy of anti DBL4e-VAR2CSA antibodies in inhibition of CSA-binding Plasmodium falciparum-infected erythrocytes from pregnant women

    Magistrado, P. A., Minja, D., Doritchamou, J., Ndam, N. T., John, D., Schmiegelow, Christentze, Massougbodji, A., Dahlbäck, M., Ditlev, S. B., Pinto, V. V., Resende, M., Lusingu, J., Theander, Thor Grundtvig, Salanti, Ali & Nielsen, Morten Agertoug, 2011, In: Vaccine. 29, 3, p. 437-43 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Positive selection of Plasmodium falciparum parasites with multiple var2csa-type PfEMP1 genes during the course of infection in pregnant women

    Sander, A. F., Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Leke, R. G. F., Lo, Y. Y., Bobbili, N., Arnot, D. E. & Taylor, D. W., 2011, In: Journal of Infectious Diseases. 203, 11, p. 1679-85 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The NTS-DBL2X region of VAR2CSA Induces cross-reactive antibodies that inhibit adhesion of several Plasmodium falciparum isolates to chondroitin sulfate A

    Bigey, P., Gnidehou, S., Doritchamou, J., Quiviger, M., Viwami, F., Couturier, A., Salanti, Ali, Nielsen, Morten Agertoug, Scherman, D., Deloron, P. & Tuikue Ndam, N., 2011, In: Journal of Infectious Diseases. 204, 7, p. 1125-33 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The chondroitin sulfate A-binding site of the VAR2CSA protein involves multiple N-terminal domains

    Dahlbäck, M., Jørgensen, L. M., Nielsen, Morten Agertoug, Clausen, T. M., Ditlev, S. B., Resende, M., Pinto, V. V., Arnot, D. E., Theander, Thor Grundtvig & Salanti, Ali, 2011, In: The Journal of Biological Chemistry. 286, 18, p. 15908-17 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2010
  22. Published

    Can any lessons be learned from the ambiguous glycan binding of PfEMP1 domains?

    Dahlbäck, M., Nielsen, Morten Agertoug & Salanti, Ali, 2010, In: Trends in Parasitology. 26, 5, p. 230-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Full-length recombinant Plasmodium falciparum VAR2CSA binds specifically to CSPG and induces potent parasite adhesion blocking antibodies

    Khunrae, P., Dahlbäck, M., Nielsen, Morten Agertoug, Andersen, G., Ditlev, S. B., Resende, M., Pinto, V. V., Theander, Thor Grundtvig, Higgins, M. K. & Salanti, Ali, 2010, In: Journal of Molecular Biology. 397, p. 826-834

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Several domains from VAR2CSA can induce Plasmodium falciparum adhesion-blocking antibodies

    Salanti, Ali, Resende, M., Ditlev, S. B., Pinto, V. V., Dahlbäck, M., Andersen, G., Manczak, T., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2010, In: Malaria Journal. 9, 1, p. 11

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2009
  26. Published

    An upstream open reading frame controls translation of var2csa, a gene implicated in placental malaria

    Amulic, B., Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten Agertoug & Deitsch, K. W., 2009, In: PLoS Pathogens. 5, 1, p. e1000256

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Chondroitin sulphate A (CSA)-binding of single recombinant Duffy-binding-like domains is not restricted to Plasmodium falciparum Erythrocyte Membrane Protein 1 expressed by CSA-binding parasites

    Resende, M., Ditlev, S. B., Nielsen, Morten Agertoug, Bodevin, S., Bruun, S., Pinto, V. V., Clausen, Henrik, Turner, Louise, Theander, Thor Grundtvig, Salanti, Ali & Dahlbäck, M., 2009, In: International Journal for Parasitology. 39, 11, p. 1195-204 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Induction of adhesion-inhibitory antibodies against placental Plasmodium falciparum parasites by using single domains of VAR2CSA

    Nielsen, Morten Agertoug, Pinto, V. V., Resende, M., Dahlbäck, M., Ditlev, S. B., Theander, Thor Grundtvig & Salanti, Ali, 2009, In: Infection and Immunity. 77, 6, p. 2482-7 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Multiple var2csa-type PfEMP1 genes located at different chromosomal loci occur in many Plasmodium falciparum isolates

    Sander, Adam F. , Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten Agertoug, Magistrado, P., Lusingu, J., Ndam, N. T. & Arnot, D. E., 2009, In: PLoS ONE. 4, 8, p. e6667

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Preferential transcription of conserved rif genes in two phenotypically distinct Plasmodium falciparum parasite lines

    Wang, Christian William, Magistrado, P. A., Nielsen, Morten Agertoug, Theander, Thor Grundtvig & Lavstsen, Thomas, 2009, In: International Journal for Parasitology. 39, 6, p. 655-64 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2008
  32. Published

    Plasmodium falciparum transcriptome analysis reveals pregnancy malaria associated gene expression

    Tuikue Ndam, N., Bischoff, E., Proux, C., Lavstsen, Thomas, Salanti, Ali, Guitard, J., Nielsen, Morten Agertoug, Coppée, J., Gaye, A., Theander, Thor Grundtvig, David, P. H. & Deloron, P., 2008, In: PLoS ONE. 3, 3, p. e1855

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Differences in human antibody reactivity to Plasmodium falciparum variant surface antigens are dependent on age and malaria transmission intensity in northeastern Tanzania

    Vestergaard, L. S., Lusingu, J. P., Nielsen, Morten Agertoug, Mmbando, B. P., Dodoo, D., Akanmori, B. D., Alifrangis, Michael, Bygbjerg, Ib Christian, Lemnge, M. M., Staalsoe, T., Hviid, Lars & Theander, Thor Grundtvig, 2008, In: Infection and Immunity. 76, 6, p. 2706-14 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 3145601