Morten Agertoug Nielsen
Professor
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4-Aminoquinoline derivatives: Synthesis, in vitro and in vivo antiplasmodial activity against chloroquine-resistant parasites
Singh, S., Agarwal, D., Sharma, K., Sharma, M., Nielsen, Morten Agertoug, Alifrangis, Michael, Singh, A. K., Gupta, R. D. & Awasthi, S. K., 21 Oct 2016, In: European Journal of Medicinal Chemistry. 122, p. 394-407 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Baculovirus-expressed constructs induce immunoglobulin G that recognizes VAR2CSA on Plasmodium falciparum-infected erythrocytes
Barfod, Lea Klingenberg, Nielsen, Morten Agertoug, Turner, Louise, Dahlbäck, M., Jensen, Anja Ramstedt, Hviid, Lars, Theander, Thor Grundtvig & Salanti, Ali, 2006, In: Infection and Immunity. 74, 7, p. 4357-60 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro selection of Plasmodium falciparum 3D7 for expression of variant surface antigens associated with severe malaria in African children
Staalsoe, T., Nielsen, Morten Agertoug, Vestergaard, L. S., Jensen, Anja Ramstedt, Theander, Thor Grundtvig & Hviid, Lars, 2003, In: Parasite Immunology. 25, 8-9, p. 421-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes
Jensen, Anja Ramstedt, Magistrado, P., Sharp, S., Joergensen, L., Lavstsen, Thomas, Chiucchiuini, A., Salanti, Ali, Vestergaard, L. S., Lusingu, J. P., Hermsen, R., Sauerwein, R., Christensen, J., Nielsen, Morten Agertoug, Hviid, Lars, Sutherland, C., Staalsoe, T. & Theander, Thor Grundtvig, 2004, In: Journal of Experimental Medicine. 199, 9, p. 1179-90 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum transcriptome analysis reveals pregnancy malaria associated gene expression
Tuikue Ndam, N., Bischoff, E., Proux, C., Lavstsen, Thomas, Salanti, Ali, Guitard, J., Nielsen, Morten Agertoug, Coppée, J., Gaye, A., Theander, Thor Grundtvig, David, P. H. & Deloron, P., 2008, In: PLoS ONE. 3, 3, p. e1855Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum variant surface antigen expression varies between isolates causing severe and nonsevere malaria and is modified by acquired immunity
Nielsen, Morten Agertoug, Staalsoe, T., Kurtzhals, Jørgen, Goka, B. Q., Dodoo, D., Alifrangis, Michael, Theander, Thor Grundtvig, Akanmori, B. D. & Hviid, Lars, 2002, In: Journal of Immunology. 168, 7, p. 3444-50 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum: VAR2CSA expressed during pregnancy-associated malaria is partially resistant to proteolytic cleavage by trypsin
Nielsen, Morten Agertoug, Resende, M., Alifrangis, Michael, Turner, Louise, Hviid, Lars, Theander, Thor Grundtvig & Salanti, Ali, 2007, In: Experimental Parasitology. 117, 1, p. 1-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Aotus nancymaae model predicts human immune response to the placental malaria vaccine candidate VAR2CSA
Doritchamou, J., Nielsen, M. A., Chêne, A., Viebig, N. K., Lambert, L. E., Sander, A. F., Semblat, J. P., Hundt, S., Orr-Gonzalez, S., Janitzek, C. M., Spiegel, A. J., Clemmensen, S. B., Thomas, M. L., Nason, M. C., Snow-Smith, M., Barnafo, E. K., Shiloach, J., Chen, B. B., Nadakal, S., Highsmith, K. & 15 others, , 2023, In: Lab Animal. 52, 12, p. 315-323Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum VAR2CSA-specific IgG subclass responses reflect protection against low birth weight and pregnancy-associated malaria
Tornyigah, B., d'Almeida, T., Escriou, G., Viwami, F., Fievet, N., Luty, A. J. F., Massougbodji, A., Nielsen, Morten Agertoug, Deloron, P. & Tuikue Ndam, N., 2021, In: Frontiers in Immunology. 12, 8 p., 610305.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum infection early in pregnancy has profound consequences for fetal growth
Schmiegelow, Christentze, Matondo, S., Minja, D. T. R., Resende, M., Pehrson, Caroline, Nielsen, B. B., Olomi, R., Nielsen, Morten Agertoug, Deloron, P., Salanti, Ali, Lusingu, J. & Theander, Thor Grundtvig, 19 Dec 2017, In: The Journal of Infectious Diseases. 216, 12, p. 1601-1610 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A VAR2CSA:CSP conjugate capable of inducing dual specificity antibody responses
Matondo, S., Thrane, Susan, Janitzek, C. M., Kavishe, R. A., Mwakalinga, S. B., Theander, Thor Grundtvig, Salanti, Ali, Nielsen, Morten Agertoug & Sander, Adam F. , 2017, In: African Health Sciences. 17, 2, p. 373-381 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Virus-like Particle-Based F4 Enterotoxigenic Escherichia coli Vaccine Is Inhibited by Maternally Derived Antibodies in Piglets but Generates Robust Responses in Sows
Aves, Kara-Lee, Guerra, Priscila Regina, Fresno, A. H., Saraiva, M. M. S., Cox, E., Bækbo, P. J., Nielsen, Morten Agertoug, Sander, Adam F. & Olsen, John Elmerdahl, 2023, In: Pathogens. 12, 12, 19 p., 1388.Research output: Contribution to journal › Journal article › Research › peer-review
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A cVLP-based vaccine displaying full-length PCSK9 elicits a higher reduction in plasma PCSK9 than similar peptide-based cVLP vaccines
Goksøyr, L., Skrzypczak, M., Sampson, M., Nielsen, Morten Agertoug, Salanti, Ali, Theander, Thor Grundtvig, Remaley, A. T., Jongh, W. A. D. & Sander, Adam F. , 2023, In: Vaccines. 11, 1, 2.Research output: Contribution to journal › Journal article › Research › peer-review
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A capsid virus-like particle-based SARS-CoV-2 vaccine induces high levels of antibodies and protects Rhesus macaques
Volkmann, A., Koopman, G., Mooij, P., Verschoor, E. J., Verstrepen, B. E., Bogers, W. M. J. M., Idorn, M., Paludan, S. R., Vang, S., Nielsen, Morten Agertoug, Sander, Adam F. , Schmittwolf, C., Hochrein, H. & Chaplin, P., 2022, In: Frontiers in Immunology. 13, p. 857440Research output: Contribution to journal › Journal article › Research › peer-review
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A novel virus-like particle based vaccine platform displaying the placental malaria antigen VAR2CSA
Thrane, Susan, Janitzek, C. M., Agerbæk, Mette Ørskov, Ditlev, S. B., dos Santos Marques Resende, M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Salanti, Ali & Sander, Adam F. , 2015, In: PloS one. 10, 11, 16 p., e0143071.Research output: Contribution to journal › Journal article › Research › peer-review
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A proof-of-concept study for the design of a VLP-based combinatorial HPV and placental malaria vaccine
Janitzek, C. M., Peabody, J., Thrane, Susan, H R Carlsen, P., Theander, Thor Grundtvig, Salanti, Ali, Chackerian, B., Nielsen, Morten Agertoug & Sander, Adam F. , 2019, In: Scientific Reports. 9, 1, 10 p., 5260.Research output: Contribution to journal › Journal article › Research › peer-review
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A sub-family of common and highly conserved Plasmodium falciparum var genes
Salanti, Ali, Jensen, Anja Ramstedt, Zornig, H. D., Staalsoe, T., Joergensen, L., Nielsen, Morten Agertoug, Khattab, A., Arnot, D. E., Klinkert, M. Q., Hviid, Lars & Theander, Thor Grundtvig, 2002, In: Molecular and Biochemical Parasitology. 122, 1, p. 111-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A vaccine displaying a trimeric influenza-A HA stem protein on capsid-like particles elicits potent and long-lasting protection in mice
Thrane, Susan, Aves, Kara-Lee, Uddbäck, Ida Elin Maria, Janitzek, C. M., Han, J., Yang, Y. R., Ward, A. B., Theander, Thor Grundtvig, Nielsen, Morten Agertoug, Salanti, Ali, Thomsen, Allan Randrup, Christensen, Jan Pravsgaard & Sander, Adam F. , 2020, In: Vaccines. 8, 3, 389.Research output: Contribution to journal › Journal article › Research › peer-review
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Adhesion of Plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue: a novel model of placental malaria
Pehrson, Caroline, Mathiesen, Line, Heno, K. K., Salanti, Ali, dos Santos Marques Resende, M., Dzikowski, R., Damm, Peter, Hansson, S. R., King, C. L., Schneider, H., Wang, Christian William, Lavstsen, Thomas, Theander, Thor Grundtvig, Knudsen, Lisbeth E. & Nielsen, Morten Agertoug, 26 May 2016, In: Malaria Journal. 15, 12 p., 292.Research output: Contribution to journal › Journal article › Research › peer-review
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Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination
Larsen, M. D., Lopez-Perez, Mary, Dickson, E. K., Ampomah, P., Tuikue Ndam, N., Nouta, J., Koeleman, C. A. M., Ederveen, A. L. H., Mordmüller, B., Salanti, Ali, Nielsen, Morten Agertoug, Massougbodji, A., van der Schoot, C. E., Ofori, M. F., Wuhrer, M., Hviid, Lars & Vidarsson, G., 2021, In: Nature Communications. 12, 5838.Research output: Contribution to journal › Journal article › Research › peer-review
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Age-dependent occurrence of the intestinal ciliate Balantidium coli in pigs at a Danish research farm
Hindsbo, O., Nielsen, C. V., Andreassen, J., Willingham, A. L., Bendixen, M., Nielsen, Morten Agertoug & Nielsen, N. O., 2000, In: Acta Veterinaria Scandinavica (Print Edition). 41, p. 79-83 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An S1-Nanoparticle Vaccine Protects against SARS-CoV-2 Challenge in K18-hACE2 Mice
van Oosten, L., Yan, K., Rawle, D. J., Le, T. T., Altenburg, J. J., Fougeroux, Cyrielle Elyette, Goksøyr, L., de Jongh, W. A., Nielsen, Morten Agertoug, Sander, Adam F. , Pijlman, G. P. & Suhrbier, A., 2022, In: Journal of Virology. 96, 14, 00844-22.Research output: Contribution to journal › Letter › Research › peer-review
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An upstream open reading frame controls translation of var2csa, a gene implicated in placental malaria
Amulic, B., Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten Agertoug & Deitsch, K. W., 2009, In: PLoS Pathogens. 5, 1, p. e1000256Research output: Contribution to journal › Journal article › Research › peer-review
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Bacterial superglue enables easy development of efficient virus-like particle based vaccines
Thrane, Susan, Janitzek, C. M., Matondo, S., dos Santos Marques Resende, M., Gustavsson, Tobias, De Jongh, W. A., Clemmensen, S., Roeffen, W., van de Vegte-Bolmer, M., van Gemert, G. J., Sauerwein, R., Schiller, J. T., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Salanti, Ali & Sander, Adam F. , 27 Apr 2016, In: Journal of Nanobiotechnology. 14, 16 p., 30.Research output: Contribution to journal › Journal article › Research › peer-review
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Bacterial superglue generates a full-length circumsporozoite protein virus-like particle vaccine capable of inducing high and durable antibody responses
Janitzek, C. M., Matondo, S., Thrane, Susan, Nielsen, Morten Agertoug, Kavishe, R., Mwakalinga, S. B., Theander, Thor Grundtvig, Salanti, Ali & Sander, Adam F. , 8 Nov 2016, In: Malaria Journal. 15, 9 p., 545.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 3145601
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Bacterial superglue enables easy development of efficient virus-like particle based vaccines
Research output: Contribution to journal › Journal article › Research › peer-review
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508
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Placental sequestration of Plasmodium falciparum malaria parasites is mediated by the interaction between VAR2CSA and chondroitin sulfate A on syndecan-1
Research output: Contribution to journal › Journal article › Research › peer-review
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Adhesion of Plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue: a novel model of placental malaria
Research output: Contribution to journal › Journal article › Research › peer-review
Published