Morten Agertoug Nielsen

Morten Agertoug Nielsen

Professor

Member of:

  • VAR2CSA team


  1. Published

    Determinants of variant surface antigen antibody response in severe Plasmodium falciparum malaria in an area of low and unstable malaria transmission

    A-Elgadir, T. M. E., Theander, Thor Grundtvig, Elghazali, G., Nielsen, Morten Agertoug, A-Elbasit, I. E., Adam, I., Troye-Blomberg, M., Elbashir, M. I. & Giha, H. A., 2006, In: Scandinavian Journal of Immunology. 63, 3, p. 232-40 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Burkitt lymphoma expresses oncofetal chondroitin sulfate without being a reservoir for placental malaria sequestration

    Agerbaek, M. Ø., Bento Ayres Pereira, M. M., Clausen, T. M., Pehrson, C., Oo, H. Z., Spliid, C., Rich, J. R., Fung, V., Nkrumah, F., Neequaye, J., Biggar, R. J., Reynolds, S. J., Tosato, G., Pullarkat, S. T., Ayers, L. W., Theander, T. G., Daugaard, M., Bhatia, K., Nielsen, M. A., Mbulaiteye, S. M. & 1 others, Salanti, Ali, 2017, In: International Journal of Cancer. 140, 7, p. 1597–1608 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner

    Agerbæk, Mette Ørskov, Bang-Christensen, S. R., Yang, M., Clausen, Thomas Mandel, Pereira, M. A., Sharma, S., Ditlev, S. B., Nielsen, Morten Agertoug, Choudhary, Swati, Gustavsson, Tobias, Sorensen, P. H., Meyer, T., Propper, D., Shamash, J., Theander, Thor Grundtvig, Aicher, A., Daugaard, M., Heeschen, C. & Salanti, Ali, 2018, In: Nature Communications. 9, 1, 13 p., 3279.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Developing a multivariate prediction model of antibody features associated with protection of malaria-infected pregnant women from placental malaria

    Aitken, E. H., Damelang, T., Ortega-Pajares, A., Alemu, A., Hasang, W., Dini, S., Unger, H. W., Ome-Kaius, M., Nielsen, Morten Agertoug, Salanti, Ali, Smith, J., Kent, S., Hogarth, P. M., Wines, B. D., Simpson, J. A., Chung, A. & Rogerson, S. J., 2021, In: eLife. 10, e65776.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    An upstream open reading frame controls translation of var2csa, a gene implicated in placental malaria

    Amulic, B., Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten Agertoug & Deitsch, K. W., 2009, In: PLoS Pathogens. 5, 1, p. e1000256

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Structural insight into epitopes in the pregnancy-associated malaria protein VAR2CSA

    Andersen, P., Nielsen, Morten Agertoug, Resende, M., Rask, T. S., Dahlbäck, M., Theander, Thor Grundtvig, Lund, O. & Salanti, Ali, 2008, In: PLoS Pathogens. 4, 2, p. e42

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Novel adenovirus encoded virus-like particles displaying the placental malaria associated VAR2CSA antigen

    Andersson, A. C., dos Santos Marques Resende, M., Salanti, Ali, Nielsen, Morten Agertoug & Holst, Peter Johannes, 22 Feb 2017, In: Vaccine. 35, 8, p. 1140-1147 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Insecticide-treated bed nets reduce plasma antibody levels and limit the repertoire of antibodies to Plasmodium falciparum variant surface antigens

    Askjaer, N., Maxwell, C., Chambo, W., Staalsoe, T., Nielsen, Morten Agertoug, Hviid, Lars, Curtis, C. & Theander, Thor Grundtvig, 2001, In: Clinical and Vaccine Immunology. 8, 6, p. 1289-91 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    A Virus-like Particle-Based F4 Enterotoxigenic Escherichia coli Vaccine Is Inhibited by Maternally Derived Antibodies in Piglets but Generates Robust Responses in Sows

    Aves, Kara-Lee, Guerra, Priscila Regina, Fresno, A. H., Saraiva, M. M. S., Cox, E., Bækbo, P. J., Nielsen, Morten Agertoug, Sander, Adam F. & Olsen, John Elmerdahl, 2023, In: Pathogens. 12, 12, 19 p., 1388.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Placental sequestration of Plasmodium falciparum malaria parasites is mediated by the interaction between VAR2CSA and chondroitin sulfate A on syndecan-1

    Ayres Pereira, M., Clausen, Thomas Mandel, Pehrson, Caroline, Mao, Y., Resende, M., Daugaard, M., Riis Kristensen, A., Spliid, C. B., Mathiesen, Line, Knudsen, Lisbeth E., Damm, Peter, Theander, Thor Grundtvig, R Hansson, S., Nielsen, Morten Agertoug & Salanti, Ali, Aug 2016, In: P L o S Pathogens. 12, 8, 26 p., e1005831.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA

    Barfod, Lea Klingenberg, Bernasconi, N. L., Dahlbäck, M., Jarrossay, D., Andersen, P. H., Salanti, Ali, Ofori, M. F., Turner, Louise, Resende, M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sallusto, F., Lanzavecchia, A. & Hviid, Lars, 2007, In: Molecular Microbiology. 63, 2, p. 335-47 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Baculovirus-expressed constructs induce immunoglobulin G that recognizes VAR2CSA on Plasmodium falciparum-infected erythrocytes

    Barfod, Lea Klingenberg, Nielsen, Morten Agertoug, Turner, Louise, Dahlbäck, M., Jensen, Anja Ramstedt, Hviid, Lars, Theander, Thor Grundtvig & Salanti, Ali, 2006, In: Infection and Immunity. 74, 7, p. 4357-60 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Plasmodium falciparum Expressing Domain Cassette 5 Type PfEMP1 (DC5-PfEMP1) Bind PECAM1

    Berger, S. S., Turner, Louise, Wang, Christian William, Petersen, J. E. V., Kraft, M., Lusingu, J. P. A., Mmbando, B., Marquard, A. M., Bengtsson, D. B. A. C., Hviid, Lars, Nielsen, Morten Agertoug, Theander, Thor Grundtvig & Lavstsen, Thomas, 2013, In: PloS one. 8, 7, p. e69117

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The NTS-DBL2X region of VAR2CSA Induces cross-reactive antibodies that inhibit adhesion of several Plasmodium falciparum isolates to chondroitin sulfate A

    Bigey, P., Gnidehou, S., Doritchamou, J., Quiviger, M., Viwami, F., Couturier, A., Salanti, Ali, Nielsen, Morten Agertoug, Scherman, D., Deloron, P. & Tuikue Ndam, N., 2011, In: Journal of Infectious Diseases. 204, 7, p. 1125-33 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Clinical development of placental malaria vaccines and immunoassays harmonization: a workshop report

    Chêne, A., Houard, S., Nielsen, Morten Agertoug, Hundt, S., D'Alessio, F., Sirima, S. B., Luty, A. J. F., Duffy, P., Leroy, O., Gamain, B. & Viebig, N. K., 17 Sep 2016, In: Malaria Journal. 15, 11 p., 476.

    Research output: Contribution to journalComment/debateResearch

  16. Published

    Structural and functional insight into how the Plasmodium falciparum VAR2CSA protein mediates binding to chondroitin sulfate A in placental malaria

    Clausen, Thomas Mandel, Christoffersen, S., Dahlbäck, M., Langkilde, Annette Eva, Jensen, K. E., Resende, M., Agerbæk, Mette Ørskov, Andersen, D., Berisha, B., Ditlev, S. B., Pinto, V. V., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Larsen, Sine & Salanti, Ali, 2012, In: Journal of Biological Chemistry. 287, 28, p. 23332-45 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasites

    Dahlbäck, M., Lavstsen, Thomas, Salanti, Ali, Hviid, Lars, Arnot, D. E., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2007, In: Malaria Journal. 6, p. 78

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Epitope mapping and topographic analysis of VAR2CSA DBL3X involved in P. falciparum placental sequestration

    Dahlbäck, M., Rask, T. S., Andersen, P. H., Nielsen, Morten Agertoug, Ndam, N. T., Resende, M., Turner, Louise, Deloron, P., Hviid, Lars, Lund, O., Pedersen, A. G., Theander, Thor Grundtvig & Salanti, Ali, 2006, In: PLoS Pathogens. 2, 11, p. e124

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The chondroitin sulfate A-binding site of the VAR2CSA protein involves multiple N-terminal domains

    Dahlbäck, M., Jørgensen, L. M., Nielsen, Morten Agertoug, Clausen, T. M., Ditlev, S. B., Resende, M., Pinto, V. V., Arnot, D. E., Theander, Thor Grundtvig & Salanti, Ali, 2011, In: The Journal of Biological Chemistry. 286, 18, p. 15908-17 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Can any lessons be learned from the ambiguous glycan binding of PfEMP1 domains?

    Dahlbäck, M., Nielsen, Morten Agertoug & Salanti, Ali, 2010, In: Trends in Parasitology. 26, 5, p. 230-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Identification and characterization of B-cell epitopes in the DBL4e domain of VAR2CSA

    Ditlev, S. B., Nielsen, Morten Agertoug, Resende, M., Agerbæk, Mette Ørskov, Pinto, V. V., Andersen, P. H., Magistrado, P., Lusingu, J., Dahlbäck, M., Theander, Thor Grundtvig & Salanti, Ali, 2012, In: P L o S One. 7, 9, p. e43663

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Utilizing nanobody technology to target non-immunodominant domains of VAR2CSA

    Ditlev, S. B., Florea, R., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Magez, S., Boeuf, P. & Salanti, Ali, 21 Jan 2014, In: PLOS ONE. 9, 1, p. e84981

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Aotus nancymaae model predicts human immune response to the placental malaria vaccine candidate VAR2CSA

    Doritchamou, J., Nielsen, M. A., Chêne, A., Viebig, N. K., Lambert, L. E., Sander, A. F., Semblat, J. P., Hundt, S., Orr-Gonzalez, S., Janitzek, C. M., Spiegel, A. J., Clemmensen, S. B., Thomas, M. L., Nason, M. C., Snow-Smith, M., Barnafo, E. K., Shiloach, J., Chen, B. B., Nadakal, S., Highsmith, K. & 15 others, Ouahes, T., Conteh, S., Sharma, A., Torano, H., Butler, B., Reiter, K., Rausch, K. M., Scaria, P. V., Anderson, C., Narum, D. L., Salanti, Ali, Fried, M., Theander, Thor Grundtvig, Gamain, B. & Duffy, P. E., 2023, In: Lab Animal. 52, 12, p. 315-323

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Differential adhesion-inhibitory patterns of antibodies raised against two major variants of the NTS-DBL2X region of VAR2CSA

    Doritchamou, J., Bigey, P., Nielsen, Morten Agertoug, Gnidehou, S., Ezinmegnon, S., Burgain, A., Massougbodji, A., Deloron, P., Salanti, Ali & Ndam, N. T., 23 Sep 2013, In: Vaccine. 31, 41, p. 4516-22 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Identification of a Major Dimorphic Region in the Functionally Critical N-Terminal ID1 Domain of VAR2CSA

    Doritchamou, J., Sabbagh, A., Jespersen, Jakob Schmidt, Renard, E., Salanti, Ali, Nielsen, Morten Agertoug, Deloron, P. & Tuikue Ndam, N., 2015, In: PLOS ONE. 10, 9, 14 p., e0137695.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 3145601