Morten Agertoug Nielsen

Morten Agertoug Nielsen

Professor

Member of:

  • VAR2CSA team

ORCID: 0000-0003-2668-4992

Publication year:
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1 - 25 out of 95Page size: 25
  1. 2023
  2. Published

    Aotus nancymaae model predicts human immune response to the placental malaria vaccine candidate VAR2CSA

    Doritchamou, J., Nielsen, M. A., Chêne, A., Viebig, N. K., Lambert, L. E., Sander, A. F., Semblat, J. P., Hundt, S., Orr-Gonzalez, S., Janitzek, C. M., Spiegel, A. J., Clemmensen, S. B., Thomas, M. L., Nason, M. C., Snow-Smith, M., Barnafo, E. K., Shiloach, J., Chen, B. B., Nadakal, S., Highsmith, K. & 15 others, Ouahes, T., Conteh, S., Sharma, A., Torano, H., Butler, B., Reiter, K., Rausch, K. M., Scaria, P. V., Anderson, C., Narum, D. L., Salanti, Ali, Fried, M., Theander, Thor Grundtvig, Gamain, B. & Duffy, P. E., 2023, In: Lab Animal. 52, 12, p. 315-323

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    A Virus-like Particle-Based F4 Enterotoxigenic Escherichia coli Vaccine Is Inhibited by Maternally Derived Antibodies in Piglets but Generates Robust Responses in Sows

    Aves, Kara-Lee, Guerra, Priscila Regina, Fresno, A. H., Saraiva, M. M. S., Cox, E., Bækbo, P. J., Nielsen, Morten Agertoug, Sander, Adam F. & Olsen, John Elmerdahl, 2023, In: Pathogens. 12, 12, 19 p., 1388.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    A cVLP-based vaccine displaying full-length PCSK9 elicits a higher reduction in plasma PCSK9 than similar peptide-based cVLP vaccines

    Goksøyr, L., Skrzypczak, M., Sampson, M., Nielsen, Morten Agertoug, Salanti, Ali, Theander, Thor Grundtvig, Remaley, A. T., Jongh, W. A. D. & Sander, Adam F. , 2023, In: Vaccines. 11, 1, 2.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Bispecific T cell-engager targeting oncofetal chondroitin sulfate induces complete tumor regression and protective immune memory in mice

    Skeltved, Nanna, Nordmaj, Mie Anemone, Pagh-Berendtsen, Nicolai, Dagil, Robert, Stormer, E. M. R., Al-Nakouzi, N., Jiang, K., Aicher, A., Heeschen, C., Gustavsson, Tobias, Choudhary, Swati, Gögenur, Ismail, Christensen, Jan Pravsgaard, Theander, Thor Grundtvig, Daugaard, M., Salanti, Ali & Nielsen, Morten Agertoug, 2023, In: Journal of Experimental & Clinical Cancer Research. 42, 16 p., 106.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Comparative analysis of spike-specific IgG Fc glycoprofiles elicited by adenoviral, mRNA, and protein-based SARS-CoV-2 vaccines

    Van Coillie, J., Pongracz, T., Šuštić, T., Wang, W., Nouta, J., Le Gars, M., Keijzer, S., Linty, F., Cristianawati, O., Keijser, J. B. D., Visser, R., van Vught, L. A., Slim, M. A., van Mourik, N., Smit, M. J., Sander, A., Schmidt, D. E., Steenhuis, M., Rispens, T., Nielsen, M. A. & 31 others, Mordmüller, B. G., Vlaar, A. P. J., Ellen van der Schoot, C., Roozendaal, R., Wuhrer, M., Vidarsson, G., Appelman, B., van de Beek, D., Bomers, M. K., de Brabander, J., Brouwer, M. C., Buis, D. T. P., Chekrouni, N., van Gils, M. J., de Jong, M. D., Lavell, A. H. A., Olie, S. E., Peters, E. J. G., Reijnders, T. D. Y., Schinkel, M., Schuurman, A. R., Sikkens, J. J., Smulders, Y. M., Wiersinga, J. W., Spinello, A., Bassoli, C., Bestetti, G., Corbellino, M., Salanti, Ali, Theander, Thor Grundtvig & in collaboration with the UMC COVID-19 S3/HCW study group, I. C. W. T. U. C. S. S. G., 2023, In: iScience. 26, 9, p. 1-15 107619.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    First-in-human use of a modular capsid virus-like vaccine platform: An open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2

    Smit, M. J., Sander, A. F., Ariaans, M. B. P. A., Fougeroux, C., Heinzel, C., Fendel, R., Esen, M., Kremsner, P. G., Ter Heine, R., Wertheim, H. F., Idorn, M., Paludan, S. R., Underwood, A. P., Binderup, A., Ramirez, S., Bukh, J., Soegaard, M., Erdogan, S. M., Gustavsson, T., Clemmensen, S. & 14 others, Theander, Thor Grundtvig, Salanti, Ali, Hamborg, M., de Jongh, W. A., McCall, M. B. B., Nielsen, Morten Agertoug, Mordmüller, B. G., COUGH-1 trial study group, C. T. S. G., Dagil, Robert, Goksøyr, L., Hulen, T. M., Brygger, C. M. J., Khalifé, P. K. & Vidal-Calvo, E. E., 2023, In: The Lancet Microbe. 4, 3, p. e140-e148

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2022
  9. Published

    A capsid virus-like particle-based SARS-CoV-2 vaccine induces high levels of antibodies and protects Rhesus macaques

    Volkmann, A., Koopman, G., Mooij, P., Verschoor, E. J., Verstrepen, B. E., Bogers, W. M. J. M., Idorn, M., Paludan, S. R., Vang, S., Nielsen, Morten Agertoug, Sander, Adam F. , Schmittwolf, C., Hochrein, H. & Chaplin, P., 2022, In: Frontiers in Immunology. 13, p. 857440

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    An S1-Nanoparticle Vaccine Protects against SARS-CoV-2 Challenge in K18-hACE2 Mice

    van Oosten, L., Yan, K., Rawle, D. J., Le, T. T., Altenburg, J. J., Fougeroux, Cyrielle Elyette, Goksøyr, L., de Jongh, W. A., Nielsen, Morten Agertoug, Sander, Adam F. , Pijlman, G. P. & Suhrbier, A., 2022, In: Journal of Virology. 96, 14, 00844-22.

    Research output: Contribution to journal › Letter › Research › peer-review

  11. Published

    Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA

    Raghavan, Sai Sundar Rajan, Dagil, Robert, Lopez-Perez, Mary, Conrad, J., Bassi, Maria Rosaria, Quintana Varon, Maria del Pilar, Choudhary, Swati, Gustavsson, Tobias, Wang, Y., Gourdon, Pontus Emanuel, Ofori, M. F., Christensen, S. B., Minja, D. T. R., Schmiegelow, Christentze, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Hviid, Lars, Salanti, Ali, Lavstsen, Thomas & Wang, Kaituo, 2022, In: PLoS Pathogens. 18, 11, e1010924.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The C-terminal tail of α-synuclein protects against aggregate replication but is critical for oligomerization

    Farzadfard, A., Pedersen, J. N., Meisl, G., Somavarapu, A. K., Alam, P., Goksøyr, L., Nielsen, Morten Agertoug, Sander, Adam F. , Knowles, T. P. J., Pedersen, J. S. & Otzen, D. E., 2022, In: Communications Biology . 5, 1, 123.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Two-component vaccine consisting of virus-like particles displaying hepatitis C virus envelope protein 2 oligomers

    Prentø, Jannick, Janitzek, C. M., Velázquez-Moctezuma, R., Sørensen, Andreas Holst Holmegaard, Jørgensen, T., Clemmensen, S., Soroka, V., Thrane, Susan, Theander, Thor Grundtvig, Nielsen, Morten Agertoug, Salanti, Ali, Bukh, Jens & Sander, Adam F. , 2022, In: npj Vaccines. 7, 148.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2021
  15. Published

    Two-component nanoparticle vaccine displaying glycosylated spike S1 domain induces neutralizing antibody response against SARS-CoV-2 variants

    van Oosten, L., Altenburg, J. J., Fougeroux, C., Geertsema, C., van den End, F., Evers, W. A. C., Westphal, A. H., Lindhoud, S., van den Berg, W., Swarts, D. C., Deurhof, L., Suhrbier, A., Le, T. T., Torres Morales, S., Myeni, S. K., Kikkert, M., Sander, A. F., de Jongh, W. A., Dagil, R., Nielsen, M. A. & 9 others, Salanti, Ali, Søgaard, M., Keijzer, T. M. P., Weijers, D., Eppink, M. H. M., Wijffels, R. H., van Oers, M. M., Martens, D. E. & Pijlman, G. P., 26 Oct 2021, In: mBio. 12, 5, e0181321.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Plasmodium falciparum VAR2CSA-specific IgG subclass responses reflect protection against low birth weight and pregnancy-associated malaria

    Tornyigah, B., d'Almeida, T., Escriou, G., Viwami, F., Fievet, N., Luty, A. J. F., Massougbodji, A., Nielsen, Morten Agertoug, Deloron, P. & Tuikue Ndam, N., 2021, In: Frontiers in Immunology. 12, 8 p., 610305.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination

    Larsen, M. D., Lopez-Perez, Mary, Dickson, E. K., Ampomah, P., Tuikue Ndam, N., Nouta, J., Koeleman, C. A. M., Ederveen, A. L. H., Mordmüller, B., Salanti, Ali, Nielsen, Morten Agertoug, Massougbodji, A., van der Schoot, C. E., Ofori, M. F., Wuhrer, M., Hviid, Lars & Vidarsson, G., 2021, In: Nature Communications. 12, 5838.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity

    Fougeroux, C., Goksøyr, L., Idorn, M., Soroka, V., Myeni, S. K., Dagil, R., Janitzek, C. M., Søgaard, M., Aves, K-L., Horsted, E. W., Erdogan, S. M., Gustavsson, T., Dorosz, J., Clemmensen, S., Fredsgaard, L., Thrane, S., Vidal-Calvo, E. E., Khalifé, P., Hulen, T. M., Choudhary, S. & 27 others, Theisen, Michael, Singh, S. K., Garcia-Senosiain, A., Van Oosten, L., Pijlman, G., Hierzberger, B., Domeyer, T., Nalewajek, B. W., Strøbæk, A., Skrzypczak, M., Andersson, L. F., Buus, Søren, Buus, Anette Stryhn, Christensen, Jan Pravsgaard, Dalebout, T. J., Iversen, Kasper, Harritshøj, L. H., Mordmüller, B., Ullum, H., Reinert, L. S., de Jongh, W. A., Kikkert, M., Paludan, S. R., Theander, Thor Grundtvig, Nielsen, Morten Agertoug, Salanti, Ali & Sander, Adam F. , 2021, In: Nature Communications. 12, 1, p. 324

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding

    Wang, Kaituo, Dagil, Robert, Lavstsen, Thomas, Misra, S. K., Spliid, C. B., Wang, Y., Gustavsson, Tobias, Sandoval, D. R., Vidal-Calvo, E. E., Choudhary, Swati, Agerbæk, Mette Ørskov, Lindorff-Larsen, Kresten, Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sharp, J. S., Clausen, Thomas Mandel, Gourdon, Pontus Emanuel & Salanti, Ali, 2021, In: Nature Communications. 12, 1, 10 p., 2956.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Developing a multivariate prediction model of antibody features associated with protection of malaria-infected pregnant women from placental malaria

    Aitken, E. H., Damelang, T., Ortega-Pajares, A., Alemu, A., Hasang, W., Dini, S., Unger, H. W., Ome-Kaius, M., Nielsen, Morten Agertoug, Salanti, Ali, Smith, J., Kent, S., Hogarth, P. M., Wines, B. D., Simpson, J. A., Chung, A. & Rogerson, S. J., 2021, In: eLife. 10, e65776.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Development of a bispecific immune engager using a recombinant malaria protein

    Nordmaj, Mie Anemone, Roberts, M. E., Sachse, E. S., Dagil, Robert, Andersen, Anne Poder, Skeltved, Nanna, Grunddal, Kaare Villum, Erdogan, Sayit Mahmut, Choudhary, Swati, Gustavsson, Tobias, Ørum-madsen, M. S., Moskalev, I., Tian, W., Yang, Zhang, Clausen, Thomas Mandel, Theander, Thor Grundtvig, Daugaard, M., Nielsen, Morten Agertoug & Salanti, Ali, 2021, In: Cell Death & Disease. 12, 4, 11 p., 353.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Progress and insights toward an effective placental malaria vaccine

    Gamain, B., Chêne, A., Viebig, N. K., Tuikue Ndam, N. & Nielsen, Morten Agertoug, 2021, In: Frontiers in Immunology. 12, 634508.

    Research output: Contribution to journal › Review › Research › peer-review

  23. Published

    The immunogenicity of capsid-like particle vaccines in combination with different adjuvants using different routes of administration

    Janitzek, C. M., Carlsen, P. H. R., Thrane, Susan, Khanna, V. M., Jakob, V., Barnier-Quer, C., Collin, N., Theander, Thor Grundtvig, Salanti, Ali, Nielsen, Morten Agertoug & Sander, Adam F. , 2021, In: Vaccines. 9, 2, 131.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. 2020
  25. Published

    A vaccine displaying a trimeric influenza-A HA stem protein on capsid-like particles elicits potent and long-lasting protection in mice

    Thrane, Susan, Aves, Kara-Lee, Uddbäck, Ida Elin Maria, Janitzek, C. M., Han, J., Yang, Y. R., Ward, A. B., Theander, Thor Grundtvig, Nielsen, Morten Agertoug, Salanti, Ali, Thomsen, Allan Randrup, Christensen, Jan Pravsgaard & Sander, Adam F. , 2020, In: Vaccines. 8, 3, 389.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. 2019
  27. Published

    A proof-of-concept study for the design of a VLP-based combinatorial HPV and placental malaria vaccine

    Janitzek, C. M., Peabody, J., Thrane, Susan, H R Carlsen, P., Theander, Thor Grundtvig, Salanti, Ali, Chackerian, B., Nielsen, Morten Agertoug & Sander, Adam F. , 2019, In: Scientific Reports. 9, 1, 10 p., 5260.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Cross-species immune recognition between Plasmodium vivax Duffy binding protein antibodies and the Plasmodium falciparum surface antigen VAR2CSA

    Gnidehou, S., Mitran, C. J., Arango, E., Banman, S., Mena, A., Medawar, E., Lima, B. A. S., Doritchamou, J., Rajwani, J., Jin, A., Gavina, K., Ntumngia, F., Duffy, P., Narum, D., Ndam, N. T., Nielsen, M. A., Salanti, A., Kano, F. S., Carvalho, L. H., Adams, J. H. & 3 others, Maestre, A., Good, M. F. & Yanow, S. K., 2019, In: The Journal of Infectious Diseases. 219, 1, p. 110-120 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    First-in-human, randomized, double-blind clinical trial of differentially adjuvanted PAMVAC, a vaccine candidate to prevent pregnancy-associated malaria

    Mordmüller, B., Sulyok, M., Egger-Adam, D., Resende, M., de Jongh, W. A., Jensen, M. H., Smedegaard, H. H., Ditlev, S. B., Soegaard, M., Poulsen, L., Dyring, C., Calle, C. L., Knoblich, A., Ibáñez, J., Esen, M., Deloron, P., Ndam, N., Issifou, S., Houard, S., Howard, R. F. & 7 others, Reed, S. G., Leroy, O., Luty, A. J. F., Theander, Thor Grundtvig, Kremsner, P. G., Salanti, Ali & Nielsen, Morten Agertoug, 2019, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 69, 9, p. 1509-1516 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Pfs230 and Pfs48/45 fusion proteins elicit strong transmission-blocking antibody responses against Plasmodium falciparum

    Singh, S. K., Thrane, Susan, Chourasia, B. K., Teelen, K., Graumans, W., Stoter, R., van Gemert, G., van de Vegte-Bolmer, M. G., Nielsen, Morten Agertoug, Salanti, Ali, Sander, Adam F. , Sauerwein, R. W., Jore, M. M. & Theisen, Michael, 2019, In: Frontiers in Immunology. 10, 1256.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 3145601