Lars Hviid

Lars Hviid

Professor

Member of:

  • SURFACE team

ORCID: 0000-0002-1698-4927

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  1. Published

    Baculovirus-expressed constructs induce immunoglobulin G that recognizes VAR2CSA on Plasmodium falciparum-infected erythrocytes

    Barfod, Lea Klingenberg, Nielsen, Morten Agertoug, Turner, Louise, Dahlbäck, M., Jensen, Anja Ramstedt, Hviid, Lars, Theander, Thor Grundtvig & Salanti, Ali, 2006, In: Infection and Immunity. 74, 7, p. 4357-60 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    In vitro Plasmodium falciparum drug sensitivity assay: inhibition of parasite growth by incorporation of stomatocytogenic amphiphiles into the erythrocyte membrane

    Ziegler, H. L., Stærk, Dan, Christensen, J., Hviid, Lars, Hägerstrand, H. & Jaroszewski, J. W., 2002, In: Antimicrobial Agents and Chemotherapy. 46, 5, p. 1441-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    In vitro selection of Plasmodium falciparum 3D7 for expression of variant surface antigens associated with severe malaria in African children

    Staalsoe, T., Nielsen, Morten Agertoug, Vestergaard, L. S., Jensen, Anja Ramstedt, Theander, Thor Grundtvig & Hviid, Lars, 2003, In: Parasite Immunology. 25, 8-9, p. 421-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    In vivo switching between variant surface antigens in human Plasmodium falciparum infection

    Staalsoe, T., Hamad, A. A., Hviid, Lars, Elhassan, I. M., Arnot, D. E. & Theander, Thor Grundtvig, 2002, In: Journal of Infectious Diseases. 186, 5, p. 719-22 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Leishmania-specific T cells expressing interferon-¿(IFN-¿) and IL-10 upon activation are expanded in individuals cured of visceral leishmaniasis

    Kemp, K., Kemp, M., Kharazmi, A., Ismail, A., Kurtzhals, Jørgen, Hviid, Lars & Theander, Thor Grundtvig, 1999, In: Clinical and Experimental Immunology. 116, 3, p. 500-4 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes

    Jensen, Anja Ramstedt, Magistrado, P., Sharp, S., Joergensen, L., Lavstsen, Thomas, Chiucchiuini, A., Salanti, Ali, Vestergaard, L. S., Lusingu, J. P., Hermsen, R., Sauerwein, R., Christensen, J., Nielsen, Morten Agertoug, Hviid, Lars, Sutherland, C., Staalsoe, T. & Theander, Thor Grundtvig, 2004, In: Journal of Experimental Medicine. 199, 9, p. 1179-90 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Plasmodium falciparum parasites expressing pregnancy-specific variant surface antigens adhere strongly to the choriocarcinoma cell line BeWo

    Haase, R. N., Megnekou, R., Lundquist, M., Ofori, M. F., Hviid, Lars & Staalsoe, T., 2006, In: Infection and Immunity. 74, 5, p. 3035-8 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Plasmodium falciparum variant surface antigen expression varies between isolates causing severe and nonsevere malaria and is modified by acquired immunity

    Nielsen, Morten Agertoug, Staalsoe, T., Kurtzhals, Jørgen, Goka, B. Q., Dodoo, D., Alifrangis, Michael, Theander, Thor Grundtvig, Akanmori, B. D. & Hviid, Lars, 2002, In: Journal of Immunology. 168, 7, p. 3444-50 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Plasmodium falciparum: VAR2CSA expressed during pregnancy-associated malaria is partially resistant to proteolytic cleavage by trypsin

    Nielsen, Morten Agertoug, Resende, M., Alifrangis, Michael, Turner, Louise, Hviid, Lars, Theander, Thor Grundtvig & Salanti, Ali, 2007, In: Experimental Parasitology. 117, 1, p. 1-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    In vitro selection for adhesion of Plasmodium falciparum-infected erythrocytes to ABO antigens does not affect PfEMP1 and RIFIN expression

    van der Puije, W., Wang, Christian William, Sudharson, S., Hempel, C., Olsen, Rebecca Wendelboe, Dalgaard, Nanna, Ofori, M. F., Hviid, Lars, Kurtzhals, Jørgen & Staalsø, Trine, 2020, In: Scientific Reports. 10, 1, p. 12871 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Plasmodium falciparum infection and naturally acquired immunity to malaria antigens among Ghanaian children in northern Ghana

    Seidu, Zakaria, Lamptey, H., Lopez-Perez, Mary, Whittle, N. O., Oppong, S. K., Kyei-Baafour, E., Pobee, A. N. A., Adjei, G. O., Hviid, Lars & Ofori, M. F., 2023, In: Parasite Epidemiology and Control. 22, p. e00317

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Plasmodium falciparum-infected erythrocyte knob density is linked to the PfEMP1 variant expressed

    Subramani, R., Quadt, K., Jeppesen, A. E., Hempel, C., Petersen, J. E. V., Hassenkam, Tue, Hviid, Lars & Barfod, Lea Klingenberg, 2015, In: mBio. 6, 5, 7 p., e01456-15.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    A Novel Domain Cassette Identifies Plasmodium falciparum PfEMP1 Proteins Binding ICAM-1 and Is a Target of Cross-Reactive, Adhesion-Inhibitory Antibodies

    Bengtsson, A., Joergensen, L., Rask, T. S., Olsen, R. W., Andersen, M. A., Turner, Louise, Theander, Thor Grundtvig, Hviid, Lars, Higgins, M. K., Craig, A., Brown, A. & Jensen, Anja Ramstedt, 2013, In: Journal of Immunology. 190, 1, p. 240-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    A conformational epitope in placental malaria vaccine antigen VAR2CSA: What does it teach us?

    Doritchamou, J. Y. A., Renn, J. P., Hviid, Lars & Duffy, P. E., 2023, In: PLoS Pathogens. 19, 5, e1011370.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    A longitudinal study of human antibody responses to Plasmodium falciparum rhoptry-associated protein 1 in a region of seasonal and unstable malaria transmission

    Fonjungo, P. N., Elhassan, I. M., Cavanagh, D. R., Theander, Thor Grundtvig, Hviid, Lars, Roper, C., Arnot, D. E. & McBride, J. S., 1999, In: Infection and Immunity. 67, 6, p. 2975-85 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    A longitudinal study of type-specific antibody responses to Plasmodium falciparum merozoite surface protein-1 in an area of unstable malaria in Sudan

    Cavanagh, D. R., Elhassan, I. M., Roper, C., Robinson, V. J., Giha, H., Holder, A. A., Hviid, Lars, Theander, Thor Grundtvig, Arnot, D. E. & McBride, J. S., 1998, In: Journal of Immunology. 161, 1, p. 347-59 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    A new portable device for automatic controlled-gradient cryopreservation of blood mononuclear cells

    Hviid, Lars, Albeck, G., Hansen, B., Theander, Thor Grundtvig & Talbot, A., 1993, In: Journal of Immunological Methods. 157, 1-2, p. 135-42 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    A sub-family of common and highly conserved Plasmodium falciparum var genes

    Salanti, Ali, Jensen, Anja Ramstedt, Zornig, H. D., Staalsoe, T., Joergensen, L., Nielsen, Morten Agertoug, Khattab, A., Arnot, D. E., Klinkert, M. Q., Hviid, Lars & Theander, Thor Grundtvig, 2002, In: Molecular and Biochemical Parasitology. 122, 1, p. 111-5 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    A vaccine targeted specifically to prevent cerebral malaria - is there hope?

    Hviid, Lars, Lavstsen, Thomas & Jensen, Anja Ramstedt, Jul 2018, In: Expert Review of Vaccines. 17, 7, p. 565-567 3 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  20. Published

    Acquisition and decay of IgM and IgG responses to merozoite antigens after Plasmodium falciparum malaria in Ghanaian children

    Walker, Melanie Rose, Knudsen, Anne Schlitterlau, Partey, Frederica Dedo, Bassi, Maria Rosaria, Frank, A. M., Castberg, F. C., Sarbah, E. W., Ofori, M. F., Hviid, Lars & Barfod, Lea Klingenberg, 2020, In: PLoS ONE. 15, 12, p. e0243943

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Acquisition and decay of antibodies to pregnancy-associated variant antigens on the surface of Plasmodium falciparum-infected erythrocytes that protect against placental parasitemia

    Staalsoe, T., Megnekou, R., Fievét, N., Ricke, C. H., Zornig, H. D., Leke, R., Taylor, D. W., Deloron, P. & Hviid, Lars, 2001, In: Journal of Infectious Diseases. 184, 5, p. 618-26 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Acquisition of IgG to ICAM-1-Binding DBLβ Domains in the Plasmodium falciparum erythrocyte membrane protein 1 antigen family varies between Groups A, B, and C

    Olsen, Rebecca Wendelboe, Ecklu-Mensah, G., Bengtsson, A., Ofori, M. F., Kusi, K. A., Koram, K. A., Hviid, Lars, Adams, Yvonne & Jensen, Anja Ramstedt, 2019, In: Infection and Immunity. 87, 10, e00224-19.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Activation of CD8-positive suppressor cells during the malaria season

    Theander, Thor Grundtvig, Hviid, Lars, Abu-Zeid, Y. A., Abdulhadi, N. H., Saeed, B. O., Jakobsen, P. H., Jepsen, S., Bayoumi, R. A. & Jensen, J. B., 1993, In: Immunology and Infectious Diseases. 3, p. 97-102

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Activation of human T lymphocytes by Leishmania lipophosphoglycan

    Kemp, M., Theander, Thor Grundtvig, Handman, E., Hey, A. S., Kurtzhals, Jørgen, Hviid, Lars, Sørensen, A. L., Were, J. O., Koech, D. K. & Kharazmi, A., 1991, In: Scandinavian Journal of Immunology. 33, 2, p. 219-24 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Acute P. falciparum malaria induces a loss of CD28- T IFN-¿ producing cells

    Kemp, K., Akanmori, B. D., Kurtzhals, J. A. L., Adabayeri, V., Goka, B. Q. & Hviid, Lars, 2002, In: Parasite Immunology. 24, 11-12, p. 545-8 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Adhesion specificities of Plasmodium falciparum-infected erythrocytes involved in the pathogenesis of pregnancy-associated malaria

    Hviid, Lars, 2007, In: American Journal of Pathology. 170, 6, p. 1817-9 3 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  27. Published

    Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination

    Larsen, M. D., Lopez-Perez, Mary, Dickson, E. K., Ampomah, P., Tuikue Ndam, N., Nouta, J., Koeleman, C. A. M., Ederveen, A. L. H., Mordmüller, B., Salanti, Ali, Nielsen, Morten Agertoug, Massougbodji, A., van der Schoot, C. E., Ofori, M. F., Wuhrer, M., Hviid, Lars & Vidarsson, G., 2021, In: Nature Communications. 12, 5838.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Aligned hemozoin crystals in curved clusters in malarial red blood cells revealed by nanoprobe X-ray Fe fluorescence and diffraction

    Kapishnikov, S., Berthing, T., Hviid, Lars, Dierolf, M., Menzel, A., Pfeiffer, F., Als-Nielsen, Jens & Leiserowitz, L., 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 28, p. 11184-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Alkamides from Phyllanthus fraternus

    Sittie, A. A., Lemmich, E., Olsen, C. E., Hviid, Lars & Christensen, Søren Brøgger, 1998, In: Planta Medica. 64, 2, p. 192-3 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Anaemia caused by asymptomatic Plasmodium falciparum infection in semi-immune African schoolchildren

    Kurtzhals, Jørgen, Addae, M. M., Akanmori, B. D., Dunyo, S., Koram, K. A., Appawu, M. A., Nkrumah, F. K. & Hviid, Lars, 1999, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 93, 6, p. 623-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Analysis by flow cytometry of α2-macroglobulin and nonimmune IgM-binding to Plasmodium falciparum-infected erythrocytes

    Hviid, Lars & Lopez-Perez, Mary, 2022, Malaria Immunology: Targeting the Surface of Infected Erythrocytes. Humana Press, Vol. 2470. p. 435-444 10 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  32. Published

    Analysis of IgG with specificity for variant surface antigens expressed by placental Plasmodium falciparum isolates

    Khattab, A., Reinhardt, C., Staalsoe, T., Fievet, N., Kremsner, P. G., Deloron, P., Hviid, Lars & Klinkert, M., 2004, In: Malaria Journal. 3, p. 21

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Analysis of allelic cross-reactivity of monoclonal IgG antibodies by a multiplexed reverse FluoroSpot assay

    Hoffmann-Veltung, H., Anabire, Nsoh Godwin, Ofori, M. F., Janhmatz, P., Ahlborg, N., Hviid, Lars & Quintana Varon, Maria del Pilar, 2022, In: eLife. 11, p. e79245

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Anti-phosphatidylserine antibody levels are low in multigravid pregnant women in a malaria-endemic area in Nigeria, and do not correlate with anti-VAR2CSA antibodies

    Fasanya, A., Mohammed, N., Saleh, B. H., Tijani, M. K., Teleka, A., Quintana Varon, Maria del Pilar, Hviid, Lars & Persson, K. E. M., 2023, In: Frontiers in Cellular and Infection Microbiology. 13, 1130186.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Anti-phospholipid antibodies in patients with Plasmodium falciparum malaria

    Jakobsen, P. H., Morris-Jones, S. D., Hviid, Lars, Theander, Thor Grundtvig, Høier-Madsen, M., Bayoumi, R. A. & Greenwood, B. M., 1993, In: Immunology. 79, 4, p. 653-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Antibodies to the N-terminal block 2 of Plasmodium falciparum merozoite surface protein 1 are associated with protection against clinical malaria

    Cavanagh, D. R., Dodoo, D., Hviid, Lars, Kurtzhals, Jørgen, Theander, Thor Grundtvig, Akanmori, B. D., Polley, S., Conway, D. J., Koram, K. & McBride, J. S., 2004, In: Infection and Immunity. 72, 11, p. 6492-502 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Antibodies to variable Plasmodium falciparum-infected erythrocyte surface antigens are associated with protection from novel malaria infections

    Giha, H. A., Staalsoe, T., Dodoo, D., Roper, C., Satti, G. M., Arnot, D. E., Hviid, Lars & Theander, Thor Grundtvig, 2000, In: Immunology Letters. 71, 2, p. 117-26 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Antibodies to variant antigens on the surfaces of infected erythrocytes are associated with protection from malaria in Ghanaian children

    Dodoo, D., Staalsoe, T., Giha, H., Kurtzhals, Jørgen, Akanmori, B. D., Koram, K., Dunyo, S., Nkrumah, F. K., Hviid, Lars & Theander, Thor Grundtvig, 2001, In: Infection and Immunity. 69, 6, p. 3713-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Antibody reactivities to glutamate-rich peptides of Plasmodium falciparum parasites in humans from areas of different malaria endemicity

    Jakobsen, P. H., Theander, Thor Grundtvig, Hviid, Lars, Morris-Jones, S., Jensen, J. B., Bayoumi, R. A., Greenwood, B. M., Bygbjerg, Ib Christian & Heegaard, P. M., 1996, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 104, 10, p. 734-40 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Antibody responses to Rhoptry-Associated Protein-1 (RAP-1) of Plasmodium falciparum parasites in humans from areas of different malaria endemicity

    Jakobsen, P. H., Kurtzhals, Jørgen, Riley, E. M., Hviid, Lars, Theander, Thor Grundtvig, Morris-Jones, S., Jensen, J. B., Bayoumi, R. A., Ridley, R. G. & Greenwood, B. M., 1997, In: Parasite Immunology. 19, 9, p. 387-93 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    B-cell responses to pregnancy-restricted and -unrestricted Plasmodium falciparum erythrocyte membrane protein 1 antigens in Ghanaian women naturally exposed to malaria parasites

    Ampomah, P., Stevenson, L., Ofori, M. F., Barfod, Lea Klingenberg & Hviid, Lars, May 2014, In: Infection and Immunity. 82, 5, p. 1860-71 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Binding of human serum proteins to Plasmodium falciparum-infected erythrocytes and its association with malaria clinical presentation

    Lopez-Perez, Mary, van der Puije, W., Castberg, F. C., Ofori, M. F. & Hviid, Lars, 2020, In: Malaria Journal. 19, 1, 362.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Biochemical characterization, localization and immunostimulating properties of a soluble glycoprotein, Ag1, isolated from in vitro cultures of Plasmodium falciparum

    Jakobsen, P. H., Jepsen, S., Riley, E. M., Theander, Thor Grundtvig, Grellier, P., Lihme, A., Hviid, Lars, Dziegiel, Morten Hanefeld & Schrevel, J., 1990, In: Parasitology Reseach. 76, 8, p. 657-61 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Biomarker of Anopheles exposure in Ghanaian children with hemoglobin S and C

    Londono-Renteria, B., Seidu, Zakaria, Lamptey, H., Ofori, M. F., Hviid, Lars & Lopez-Perez, Mary, 2024, In: Acta Tropica. 249, 8 p., 107043.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Blood outgrowth endothelial cells (BOECs) as a novel tool for studying adhesion of Plasmodium falciparum-infected erythrocytes

    Ecklu-Mensah, G., Olsen, Rebecca Wendelboe, Bengtsson, A., Ofori, M. F., Hviid, Lars, Jensen, Anja Ramstedt & Adams, Yvonne, 2018, In: PLoS ONE. 13, 10, 12 p., e0204177.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    CCR3 expression induced by IL-2 and IL-4 functioning as a death receptor for B cells

    Jinquan, T., Jacobi, H. H., Jing, C., Millner, A., Sten, E., Hviid, Lars, Anting, L., Ryder, L. P., Glue, C., Skov, P. S., Jarman, E., Lamberth, K., Malling, H. & Poulsen, Lars K., 2003, In: Journal of Immunology. 171, 4, p. 1722-31 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    CD36 selection of 3D7 Plasmodium falciparum associated with severe childhood malaria results in reduced VAR4 expression

    Magistrado, P., Staalsoe, T., Theander, Thor Grundtvig, Hviid, Lars & Jensen, Anja Ramstedt, 2008, In: Malaria Journal. 7, 1, p. 204

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Cell-mediated immune responses to Plasmodium falciparum purified soluble antigens in sickle-cell trait subjects

    Bayoumi, R. A., Abu-Zeid, Y. A., Abdulhadi, N. H., Saeed, B. O., Theander, Thor Grundtvig, Hviid, Lars, Ghalib, H. W., Nugud, A. H., Jepsen, S. & Jensen, J. B., 1990, In: Immunology Letters. 25, 1-3, p. 243-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Cell-mediated immune responses to soluble Plasmodium falciparum antigens in residents from an area of unstable malaria transmission in the Sudan

    Hviid, Lars, Theander, Thor Grundtvig, Jakobsen, P. H., Abu-Zeid, Y. A., Abdulhadi, N. H., Saeed, B. O., Jepsen, S., Bayoumi, R. A. L., Bendtzen, K. & Jensen, J. B., 1990, In: APMIS. 98, 7-12, p. 594-604 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Cell-mediated immunity to Plasmodium falciparum infection: evidence against the involvement of cytotoxic lymphocytes

    Theander, Thor Grundtvig, Andersen, B. J., Pedersen, B. K., Jepsen, S., Bygbjerg, Ib Christian, Hviid, Lars, Larsen, P. B. & Kharazmi, A., 1988, In: Scandinavian Journal of Immunology. 28, 1, p. 105-11 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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