Morten Agertoug Nielsen

Morten Agertoug Nielsen

Professor

Member of:

  • VAR2CSA team

ORCID: 0000-0003-2668-4992

Publication year:
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  1. Published

    First-in-human use of a modular capsid virus-like vaccine platform: An open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2

    Smit, M. J., Sander, A. F., Ariaans, M. B. P. A., Fougeroux, C., Heinzel, C., Fendel, R., Esen, M., Kremsner, P. G., Ter Heine, R., Wertheim, H. F., Idorn, M., Paludan, S. R., Underwood, A. P., Binderup, A., Ramirez, S., Bukh, J., Soegaard, M., Erdogan, S. M., Gustavsson, T., Clemmensen, S. & 14 others, Theander, Thor Grundtvig, Salanti, Ali, Hamborg, M., de Jongh, W. A., McCall, M. B. B., Nielsen, Morten Agertoug, Mordmüller, B. G., COUGH-1 trial study group, C. T. S. G., Dagil, Robert, Goksøyr, L., Hulen, T. M., Brygger, C. M. J., Khalifé, P. K. & Vidal-Calvo, E. E., 2023, In: The Lancet Microbe. 4, 3, p. e140-e148

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    First-in-human, randomized, double-blind clinical trial of differentially adjuvanted PAMVAC, a vaccine candidate to prevent pregnancy-associated malaria

    Mordmüller, B., Sulyok, M., Egger-Adam, D., Resende, M., de Jongh, W. A., Jensen, M. H., Smedegaard, H. H., Ditlev, S. B., Soegaard, M., Poulsen, L., Dyring, C., Calle, C. L., Knoblich, A., Ibáñez, J., Esen, M., Deloron, P., Ndam, N., Issifou, S., Houard, S., Howard, R. F. & 7 others, Reed, S. G., Leroy, O., Luty, A. J. F., Theander, Thor Grundtvig, Kremsner, P. G., Salanti, Ali & Nielsen, Morten Agertoug, 2019, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 69, 9, p. 1509-1516 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Full-length recombinant Plasmodium falciparum VAR2CSA binds specifically to CSPG and induces potent parasite adhesion blocking antibodies

    Khunrae, P., Dahlbäck, M., Nielsen, Morten Agertoug, Andersen, G., Ditlev, S. B., Resende, M., Pinto, V. V., Theander, Thor Grundtvig, Higgins, M. K. & Salanti, Ali, 2010, In: Journal of Molecular Biology. 397, p. 826-834

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Geographical and temporal conservation of antibody recognition of Plasmodium falciparum variant surface antigens

    Nielsen, Morten Agertoug, Vestergaard, L. S., Lusingu, J., Kurtzhals, Jørgen, Giha, H. A., Grevstad, B., Goka, B. Q., Lemnge, M. M., Jensen, J. B., Akanmori, B. D., Theander, Thor Grundtvig, Staalsoe, T. & Hviid, Lars, 2004, In: Infection and Immunity. 72, 6, p. 3531-5 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    High efficacy of anti DBL4e-VAR2CSA antibodies in inhibition of CSA-binding Plasmodium falciparum-infected erythrocytes from pregnant women

    Magistrado, P. A., Minja, D., Doritchamou, J., Ndam, N. T., John, D., Schmiegelow, Christentze, Massougbodji, A., Dahlbäck, M., Ditlev, S. B., Pinto, V. V., Resende, M., Lusingu, J., Theander, Thor Grundtvig, Salanti, Ali & Nielsen, Morten Agertoug, 2011, In: Vaccine. 29, 3, p. 437-43 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    High-Throughput Testing of Antibody-Dependent Binding Inhibition of Placental Malaria Parasites

    Nielsen, Morten Agertoug & Salanti, Ali, 2015, Malaria Vaccines : Methods and Protocols . Humana Press, Vol. 1325. p. 241-53 13 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  7. Published

    Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA

    Barfod, Lea Klingenberg, Bernasconi, N. L., Dahlbäck, M., Jarrossay, D., Andersen, P. H., Salanti, Ali, Ofori, M. F., Turner, Louise, Resende, M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sallusto, F., Lanzavecchia, A. & Hviid, Lars, 2007, In: Molecular Microbiology. 63, 2, p. 335-47 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Identification and characterization of B-cell epitopes in the DBL4e domain of VAR2CSA

    Ditlev, S. B., Nielsen, Morten Agertoug, Resende, M., Agerbæk, Mette Ørskov, Pinto, V. V., Andersen, P. H., Magistrado, P., Lusingu, J., Dahlbäck, M., Theander, Thor Grundtvig & Salanti, Ali, 2012, In: P L o S One. 7, 9, p. e43663

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Identification of a Major Dimorphic Region in the Functionally Critical N-Terminal ID1 Domain of VAR2CSA

    Doritchamou, J., Sabbagh, A., Jespersen, Jakob Schmidt, Renard, E., Salanti, Ali, Nielsen, Morten Agertoug, Deloron, P. & Tuikue Ndam, N., 2015, In: PLOS ONE. 10, 9, 14 p., e0137695.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Identification of glycosaminoglycan binding regions in the Plasmodium falciparum encoded placental sequestration ligand, VAR2CSA

    Resende, M., Nielsen, Morten Agertoug, Dahlbäck, M., Ditlev, S. B., Andersen, P., Sander, A. F., Ndam, N. T., Theander, Thor Grundtvig & Salanti, Ali, 2008, In: Malaria Journal. 7, p. 104

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Improving the malaria transmission-blocking activity of a Plasmodium falciparum 48/45 based vaccine antigen by SpyTag/SpyCatcher mediated virus-like display

    Singh, S. K., Thrane, Susan, Janitzek, C. M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Theisen, Michael, Salanti, Ali & Sander, Adam F. , 2017, In: Vaccine. 35, 30, p. 3726-3732 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Induction of adhesion-inhibitory antibodies against placental Plasmodium falciparum parasites by using single domains of VAR2CSA

    Nielsen, Morten Agertoug, Pinto, V. V., Resende, M., Dahlbäck, M., Ditlev, S. B., Theander, Thor Grundtvig & Salanti, Ali, 2009, In: Infection and Immunity. 77, 6, p. 2482-7 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Insecticide-treated bed nets reduce plasma antibody levels and limit the repertoire of antibodies to Plasmodium falciparum variant surface antigens

    Askjaer, N., Maxwell, C., Chambo, W., Staalsoe, T., Nielsen, Morten Agertoug, Hviid, Lars, Curtis, C. & Theander, Thor Grundtvig, 2001, In: Clinical and Vaccine Immunology. 8, 6, p. 1289-91 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Mannose-binding lectin is a disease modifier in clinical malaria and may function as opsonin for Plasmodium falciparum-infected erythrocytes

    Garred, Peter, Nielsen, Morten Agertoug, Kurtzhals, Jørgen, Malhotra, R., Madsen, H. O., Goka, B. Q., Akanmori, B. D., Sim, R. B. & Hviid, Lars, 2003, In: Infection and Immunity. 71, 9, p. 5245-53 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Marchantin A, a macrocyclic bisbibenzyl ether, isolated from the liverwort Marchantia polymorpha, inhibits protozoal growth in vitro

    Jensen, S., Omarsdottir, S., Bwalya, A. G., Nielsen, Morten Agertoug, Tasdemir, D. & Olafsdottir, E. S., 2012, In: Phytomedicine. 19, 13, p. 1191-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Multilaboratory approach to preclinical evaluation of vaccine immunogens for placental malaria

    Fried, M., Avril, M., Chaturvedi, R., Fernandez, P., Lograsso, J., Narum, D., Nielsen, Morten Agertoug, Oleinikov, A. V., Resende, M., Salanti, Ali, Saveria, T., Williamson, K., Dicko, A., Scherf, A., Smith, J. D., Theander, Thor Grundtvig & Duffy, P. E., 2013, In: Infect Immun. 81, 2, p. 487-95 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Multiple var2csa-type PfEMP1 genes located at different chromosomal loci occur in many Plasmodium falciparum isolates

    Sander, Adam F. , Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten Agertoug, Magistrado, P., Lusingu, J., Ndam, N. T. & Arnot, D. E., 2009, In: PLoS ONE. 4, 8, p. e6667

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Novel adenovirus encoded virus-like particles displaying the placental malaria associated VAR2CSA antigen

    Andersson, A. C., dos Santos Marques Resende, M., Salanti, Ali, Nielsen, Morten Agertoug & Holst, Peter Johannes, 22 Feb 2017, In: Vaccine. 35, 8, p. 1140-1147 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Persistent Plasmodium falciparum Infection in Women With an Intent to Become Pregnant as a Risk Factor for Pregnancy-associated Malaria

    Tuikue Ndam, N., Tornyigah, B., Dossou, A. Y., Escriou, G., Nielsen, Morten Agertoug, Salanti, Ali, Issifou, S., Massougbodji, A., Chippaux, J. P. & Deloron, P., 2018, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 67, 12, p. 1890-1896 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Pfs230 and Pfs48/45 fusion proteins elicit strong transmission-blocking antibody responses against Plasmodium falciparum

    Singh, S. K., Thrane, Susan, Chourasia, B. K., Teelen, K., Graumans, W., Stoter, R., van Gemert, G., van de Vegte-Bolmer, M. G., Nielsen, Morten Agertoug, Salanti, Ali, Sander, Adam F. , Sauerwein, R. W., Jore, M. M. & Theisen, Michael, 2019, In: Frontiers in Immunology. 10, 1256.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Placental sequestration of Plasmodium falciparum malaria parasites is mediated by the interaction between VAR2CSA and chondroitin sulfate A on syndecan-1

    Ayres Pereira, M., Clausen, Thomas Mandel, Pehrson, Caroline, Mao, Y., Resende, M., Daugaard, M., Riis Kristensen, A., Spliid, C. B., Mathiesen, Line, Knudsen, Lisbeth E., Damm, Peter, Theander, Thor Grundtvig, R Hansson, S., Nielsen, Morten Agertoug & Salanti, Ali, Aug 2016, In: P L o S Pathogens. 12, 8, 26 p., e1005831.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Plasmodium falciparum Expressing Domain Cassette 5 Type PfEMP1 (DC5-PfEMP1) Bind PECAM1

    Berger, S. S., Turner, Louise, Wang, Christian William, Petersen, J. E. V., Kraft, M., Lusingu, J. P. A., Mmbando, B., Marquard, A. M., Bengtsson, D. B. A. C., Hviid, Lars, Nielsen, Morten Agertoug, Theander, Thor Grundtvig & Lavstsen, Thomas, 2013, In: PloS one. 8, 7, p. e69117

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Positive selection of Plasmodium falciparum parasites with multiple var2csa-type PfEMP1 genes during the course of infection in pregnant women

    Sander, A. F., Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Leke, R. G. F., Lo, Y. Y., Bobbili, N., Arnot, D. E. & Taylor, D. W., 2011, In: Journal of Infectious Diseases. 203, 11, p. 1679-85 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Pre-clinical and clinical development of the first placental malaria vaccine

    Pehrson, Caroline, Salanti, Ali, Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2017, In: Expert Review of Vaccines. 16, 6, p. 613-624 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Preferential transcription of conserved rif genes in two phenotypically distinct Plasmodium falciparum parasite lines

    Wang, Christian William, Magistrado, P. A., Nielsen, Morten Agertoug, Theander, Thor Grundtvig & Lavstsen, Thomas, 2009, In: International Journal for Parasitology. 39, 6, p. 655-64 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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