Lea Klingenberg Barfod
Associate Professor
- 2002
- Published
Chalcones from Chinese liquorice inhibit proliferation of T cells and production of cytokines
Barfod, Lea Klingenberg, Kemp, K., Hansen, M. & Kharazmi, A., 2002, In: International Immunopharmacology. 2, 4, p. 545-55 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
Evidence for the involvement of VAR2CSA in pregnancy-associated malaria
Salanti, Ali, Dahlbäck, M., Turner, Louise, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Magistrado, P., Jensen, Anja Ramstedt, Lavstsen, Thomas, Ofori, M. F., Marsh, K., Hviid, Lars & Theander, Thor Grundtvig, 2004, In: Journal of Experimental Medicine. 200, 9, p. 1197-203 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Baculovirus-expressed constructs induce immunoglobulin G that recognizes VAR2CSA on Plasmodium falciparum-infected erythrocytes
Barfod, Lea Klingenberg, Nielsen, Morten Agertoug, Turner, Louise, Dahlbäck, M., Jensen, Anja Ramstedt, Hviid, Lars, Theander, Thor Grundtvig & Salanti, Ali, 2006, In: Infection and Immunity. 74, 7, p. 4357-60 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
- 2007
- Published
Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA
Barfod, Lea Klingenberg, Bernasconi, N. L., Dahlbäck, M., Jarrossay, D., Andersen, P. H., Salanti, Ali, Ofori, M. F., Turner, Louise, Resende, M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sallusto, F., Lanzavecchia, A. & Hviid, Lars, 2007, In: Molecular Microbiology. 63, 2, p. 335-47 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Malaria vaccines: immunity, models and monoclonal antibodies
Hviid, Lars & Barfod, Lea Klingenberg, 2008, In: Trends in Parasitology. 24, 9, p. 392-395 3 p.Research output: Contribution to journal › Review › Research › peer-review
- 2009
- Published
Human monoclonal IgG selection of Plasmodium falciparum for the expression of placental malaria-specific variant surface antigens
Soerli, J., Barfod, Lea Klingenberg, Lavstsen, Thomas, Bernasconi, N. L., Lanzavecchia, A. & Hviid, Lars, 2009, In: Parasite Immunology. 31, 6, p. 341-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Chondroitin sulfate A-adhering Plasmodium falciparum-infected erythrocytes express functionally important antibody epitopes shared by multiple variants
Barfod, Lea Klingenberg, Dobrilovic, T., Magistrado, P., Khunrae, P., Viwami, F., Bruun, J., Dahlbäck, M., Bernasconi, N. L., Fried, M., John, D., Duffy, P. E., Salanti, Ali, Lanzavecchia, A., Lim, C. T., Ndam, N. T., Higgins, M. K. & Hviid, Lars, 2010, In: Journal of Immunology. 185, 12, p. 7553-61 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The kinetics of antibody binding to Plasmodium falciparum VAR2CSA PfEMP1 antigen and modelling of PfEMP1 antigen packing on the membrane knobs
Joergensen, L. M., Salanti, Ali, Dobrilovic, T., Barfod, Lea Klingenberg, Hassenkam, Tue, Theander, Thor Grundtvig, Hviid, Lars & Arnot, D. E., 2010, In: Malaria Journal. 9, 1, p. 100Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Evasion of immunity to Plasmodium falciparum malaria by IgM masking of protective IgG epitopes in infected erythrocyte surface-exposed PfEMP1
Barfod, Lea Klingenberg, Dalgaard, M. B., Pleman, S. T., Ofori, M. F., Pleass, R. J. & Hviid, Lars, 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 30, p. 12485-90 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
The density of knobs on Plasmodium falciparum-infected erythrocytes depends on developmental age and varies among isolates
Quadt, K. A., Barfod, Lea Klingenberg, Andersen, D., Bruun, J., Gyan, B., Hassenkam, Tue, Ofori, M. F. & Hviid, Lars, 2012, In: P L o S One. 7, 9, p. e45658Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites
Sleebs, B. E., Lopaticki, S., Marapana, D. S., O'Neill, M. T., Rajasekaran, P., Gazdik, M., Günther, S., Whitehead, L. W., Lowes, K. N., Barfod, Lea Klingenberg, Hviid, Lars, Shaw, P. J., Hodder, A. N., Smith, B. J., Cowman, A. F. & Boddey, J. A., 2014, In: P L o S Biology. 12, 7, p. e1001897Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Malaria Pigment Hemozoin Comprises at Most Four Different Isomer Units in Two Crystalline Models: Chiral as Based on a Biochemical Hypothesis or Centrosymmetric Made of Enantiomorphous Sectors
Straasø, T., Marom, N., Solomonov, I., Barfod, Lea Klingenberg, Burghammer, M., Feidenhans'l, Robert Krarup, Als-Nielsen, Jens & Leiserowitz, L., 17 Mar 2014, In: Crystal Growth & Design. 14, 4, p. 1543-1554 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
B-cell responses to pregnancy-restricted and -unrestricted Plasmodium falciparum erythrocyte membrane protein 1 antigens in Ghanaian women naturally exposed to malaria parasites
Ampomah, P., Stevenson, L., Ofori, M. F., Barfod, Lea Klingenberg & Hviid, Lars, May 2014, In: Infection and Immunity. 82, 5, p. 1860-71 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetics of B Cell responses to Plasmodium falciparum erythrocyte membrane protein 1 in Ghanaian women naturally exposed to malaria parasites
Ampomah, P., Stevenson, L., Ofori, M. F., Barfod, Lea Klingenberg & Hviid, Lars, 1 Jun 2014, In: Journal of Immunology. 192, 11, p. 5236-44 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Plasmodium falciparum-infected erythrocyte knob density is linked to the PfEMP1 variant expressed
Subramani, R., Quadt, K., Jeppesen, A. E., Hempel, C., Petersen, J. E. V., Hassenkam, Tue, Hviid, Lars & Barfod, Lea Klingenberg, 2015, In: mBio. 6, 5, 7 p., e01456-15.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mapping the binding site of a cross-reactive Plasmodium falciparum PfEMP1 monoclonal antibody inhibitory of ICAM-1 binding
Lennartz, F., Bengtsson, A., Olsen, Rebecca Wendelboe, Joergensen, L., Brown, A., Remy, L., Man, P., Forest, E., Barfod, Lea Klingenberg, Adams, Yvonne, Higgins, M. K. & Jensen, Anja Ramstedt, 2015, In: Journal of immunology (Baltimore, Md. : 1950). 195, 7, p. 3273-83 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multiple Plasmodium falciparum erythrocyte membrane protein 1 variants per genome can bind IgM via its Fc fragment Fcμ
Jeppesen, A., Ditlev, S. B., Soroka, V., Stevenson, E. K., Turner, Louise, Dzikowski, R., Hviid, Lars & Barfod, Lea Klingenberg, 2015, In: Infection and Immunity. 83, 10, p. 3972-81 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trying to remember: immunological B cell memory to malaria
Hviid, Lars, Barfod, Lea Klingenberg & Fowkes, F. J. I., Mar 2015, In: Trends in Parasitology. 31, 3, p. 89-94 6 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Investigating the function of Fc -specific binding of IgM to Plasmodium falciparum erythrocyte membrane protein 1 mediating erythrocyte rosetting
Stevenson, L., Huda, P., Jeppesen, A., Laursen, E. T. F., Rowe, J. A., Craig, A., Streicher, W., Barfod, Lea Klingenberg & Hviid, Lars, Jun 2015, In: Cellular Microbiology. 17, 6, p. 819-31 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
α2-macroglobulin can crosslink multiple Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) molecules and may facilitate adhesion of parasitized erythrocytes
Stevenson, L., Laursen, E., Cowan, G. J., Bandoh, B., Barfod, Lea Klingenberg, Cavanagh, D. R., Andersen, G. R. & Hviid, Lars, Jul 2015, In: P L o S Pathogens. 11, 7, p. 1-19 19 p., e1005022.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
One-step design of a stable variant of the malaria invasion protein RH5 for use as a vaccine immunogen
Campeotto, I., Goldenzweig, A., Davey, J., Barfod, Lea Klingenberg, Marshall, J. M., Silk, S. E., Wright, K. E., Draper, S. J., Higgins, M. K. & Fleishman, S. J., Jan 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 5, p. 998-1002 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions
Payne, R. O., Silk, S. E., Elias, S. C., Miura, K., Diouf, A., Galaway, F., de Graaf, H., Brendish, N. J., Poulton, I. D., Griffiths, O. J., Edwards, N. J., Jin, J., Labbé, G. M., Alanine, D. G., Siani, L., Di Marco, S., Roberts, R., Green, N., Berrie, E., Ishizuka, A. S. & 22 others, , Nov 2017, In: JCI insight. 2, 21, 19 p., e96381.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Kinetics of antibody responses to PfRH5-complex antigens in Ghanaian children with Plasmodium falciparum malaria
Partey, Frederica Dedo, Castberg, F. C., Sarbah, E. W., Silk, S. E., Awandare, G. A., Draper, S. J., Opoku, N., Kweku, M., Ofori, M. F., Hviid, Lars & Barfod, Lea Klingenberg, 2018, In: PLOS ONE. 13, 6, 14 p., e0198371.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
Functional comparison of blood-stage Plasmodium falciparum malaria vaccine candidate antigens
Illingworth, J. J., Alanine, D. G., Brown, R., Marshall, J. M., Bartlett, H. E., Silk, S. E., Labbé, G. M., Quinkert, D., Cho, J. S., Wendler, J. P., Pattinson, D. J., Barfod, Lea Klingenberg, Douglas, A. D., Shea, M. W., Wright, K. E., de Cassan, S. C., Higgins, M. K. & Draper, S. J., 2019, In: Frontiers in Immunology. 10, p. 1254Research output: Contribution to journal › Journal article › Research › peer-review
ID: 33042918
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Kinetics of B Cell responses to Plasmodium falciparum erythrocyte membrane protein 1 in Ghanaian women naturally exposed to malaria parasites
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
2103
downloads
Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
2066
downloads
B-cell responses to pregnancy-restricted and -unrestricted Plasmodium falciparum erythrocyte membrane protein 1 antigens in Ghanaian women naturally exposed to malaria parasites
Research output: Contribution to journal › Journal article › Research › peer-review
Published