Helle Hansson

Helle Hansson

Assistant Professor


  1. 2024
  2. Published

    A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture

    Andradi-Brown, C., Wichers-Misterek, J. S., von Thien, H., Höppner, Y. D., Scholz, J. A. M., Hansson, Helle Smedegaard, Hocke, Emma Filtenborg, Gilberger, T. W., Duffy, M. F., Lavstsen, Thomas, Baum, J., Otto, T. D., Cunnington, A. J. & Bachmann, A., 25 Jan 2024, In: eLife. 12, 38 p., RP87726.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Seasonal malaria chemoprevention therapy in children up to 9 years of age: Protocol for a cluster-randomized trial study

    Toure, M., Shaffer, J. G., Sanogo, D., Keita, S., Keita, M., Kane, F., Traore, B., Dabitao, D., Kone, A., Doumbia, C. O., Keating, J., Yukich, J., Hansson, Helle Smedegaard, Barry, A. E., Diakité, M., Alifrangis, Michael & Doumbia, S., 22 Jan 2024, In: JMIR Research Protocols. 13, p. e51660

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Identification of the PfK13 mutations R561H and P441L in the Democratic Republic of Congo

    Mesia Kahunu, G., Wellmann Thomsen, S., Wellmann Thomsen, L., Muhindo Mavoko, H., Mitashi Mulopo, P., Hocke, Emma Filtenborg, Mandoko Nkoli, P., Baraka, V., Minja, D. T. R., Mousa, A., Roper, C., Mbongi Moke, D., Mumba Ngoyi, D., Mukomena Sompwe, E., Muyembe Tanfum, J. J., Hansson, Helle Smedegaard & Alifrangis, Michael, 2024, In: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 139, p. 41-49 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2023
  6. Published

    A snapshot of the prevalence of dihydropteroate synthase-431V mutation and other sulfadoxine-pyrimethamine resistance markers in Plasmodium falciparum isolates in Nigeria

    Adegbola, A. J., Ijarotimi, O. A., Ubom, A. E., Adesoji, B. A., Babalola, O. E., Hocke, Emma Filtenborg, Hansson, Helle Smedegaard, Mousa, A., Bolaji, O. O., Alifrangis, Michael & Roper, C., 2023, In: Malaria Journal. 22, 71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Assessment of artemisinin tolerance in Plasmodium falciparum clinical isolates in children with uncomplicated malaria in Ghana

    Ahorhorlu, S. Y., Quashie, N. B., Jensen, R. W., Kudzi, W., Nartey, E. T., Duah-Quashie, N. O., Zoiku, F., Dzudzor, B., Wang, Christian William, Hansson, Helle Smedegaard, Alifrangis, Michael & Adjei, G. O., 2023, In: Malaria Journal. 22, 58.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Effect of monthly intermittent preventive treatment with dihydroartemisinin-piperaquine with and without azithromycin versus monthly sulfadoxine-pyrimethamine on adverse pregnancy outcomes in Africa: a double-blind randomised, partly placebo-controlled trial

    Madanitsa, M., Barsosio, H. C., Minja, D. T. R., Mtove, G., Kavishe, R. A., Dodd, J., Saidi, Q., Onyango, E. D., Otieno, K., Wang, D., Ashorn, U., Hill, J., Mukerebe, C., Gesase, S., Msemo, O. A., Mwapasa, V., Phiri, K. S., Maleta, K., Klein, N., Magnussen, P. & 9 others, Lusingu, J. P. A., Kariuki, S., Mosha, J. F., Alifrangis, Michael, Hansson, Helle Smedegaard, Schmiegelow, Christentze, Gutman, J. R., Chico, R. M. & Ter Kuile, F. O., 2023, In: The Lancet. 401, 10381, p. 1020-1036 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Evolution of Plasmodium falciparum antimalarial drug resistance markers post-adoption of artemisinin-based combination therapies in Yaounde, Cameroon

    Niba, P. T. N., Nji, A. M., Chedjou, J. P. K., Hansson, Helle Smedegaard, Hocke, Emma Filtenborg, Ali, I. M., Achonduh-Atijegbe, O., Evehe, M. S. B., Jørgensen, M. H. M., Fomboh, C. T., Cui, L., Stresman, G., Bigoga, J. D., Alifrangis, Michael & Mbacham, W. F., 2023, In: International Journal of Infectious Diseases. 132, p. 108-117 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Fetal growth and birth weight are independently reduced by malaria infection and curable sexually transmitted and reproductive tract infections in Kenya, Tanzania, and Malawi: A pregnancy cohort study

    Mtove, G., Chico, R. M., Madanitsa, M., Barsosio, H. C., Msemo, O. A., Saidi, Q., Gore-Langton, G. R., Minja, D. T. R., Mukerebe, C., Gesase, S., Mwapasa, V., Phiri, K. S., Hansson, H., Dodd, J., Magnussen, P., Kavishe, R. A., Mosha, F., Kariuki, S., Lusingu, J. P. A., Gutman, J. R. & 3 others, Alifrangis, Michael, Ter Kuile, F. O. & Schmiegelow, Christentze, 2023, In: International Journal of Infectious Diseases. 135, p. 28-40 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2022
  12. Published

    Attributable risk factors for asymptomatic malaria and anaemia and their association with cognitive and psychomotor functions in schoolchildren of north-eastern Tanzania

    Makenga, G., Baraka, V., Francis, F., Minja, D. T. R., Gesase, S., Kyaruzi, E., Mtove, G., Nakato, S., Madebe, R., Søeborg, S. R., Langhoff, K. H., Hansson, Helle Smedegaard, Alifrangis, Michael, Lusingu, J. P. A. & Van Geertruyden, J., 2022, In: PLoS ONE. 17, 5, e0268654.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    High DDT resistance without apparent association to kdr and Glutathione-S-transferase (GST) gene mutations in Aedes aegypti population at hotel compounds in Zanzibar

    Kampango, A., Hocke, Emma Filtenborg, Hansson, Helle Smedegaard, Furu, Peter, Haji, K. A., David, J., Konradsen, Flemming, Saleh, F., Weldon, C. W., Schiøler, Karin Linda & Alifrangis, Michael, 2022, In: PLOS Neglected Tropical Diseases . 16, 5, 17 p., e0010355.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Preservation and extraction of malaria parasite DNA from dried blood spots

    Hansson, Helle Smedegaard, Saidi, Queen & Alifrangis, Michael, 2022, Malaria Immunology: Targeting the Surface of Infected Erythrocytes. Human Kinetics, Vol. 2470. p. 27-36 10 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  15. 2021
  16. Published

    Common virulence gene expression in adult first-time infected malaria patients and severe cases

    Wichers, J. S., Tonkin-Hill, G., Thye, T., Krumkamp, R., Kreuels, B., Strauss, J., von Thien, H., Scholz, J. A. M., Smedegaard Hansson, H., Weisel Jensen, R., Turner, L., Lorenz, F-R., Schöllhorn, A., Bruchhaus, I., Tannich, E., Fendel, R., D Otto, T., Lavstsen, T., Gilberger, T. W., Duffy, M. & 1 others, Bachmann, A., 2021, In: eLife. 10, e69040.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Identification of single-nucleotide polymorphisms in the mitochondrial genome and kelch 13 gene of Plasmodium falciparum in different geographical populations

    Nydahl, T. K., Ahorhorlu, S. Y., Ndiaye, M., Das, M. K., Hansson, Helle Smedegaard, Crespo Bravo, Marina, Wang, Christian William, Lusingu, J., Theisen, Michael, Singh, S. K., Singh, S., Campino, S., Lund, O., Roper, C. & Alifrangis, Michael, 2021, In: American Journal of Tropical Medicine and Hygiene. 105, 4, p. 1085-1092 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Reduced birth weight caused by sextuple drug resistant Plasmodium falciparum infection in early second trimester

    Hansson, Helle Smedegaard, Minja, D. T. R., Moeller, S. L., Lusingu, J. P. A., Bygbjerg, Ib Christian, Yde, A., Jensen, R. W., Nag, S., Msemo, O. A., Theander, Thor Grundtvig, Alifrangis, Michael & Schmiegelow, Christentze, 2021, In: The Journal of Infectious Diseases. 224, 9, p. 1605–1613

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Ultrasensitive qPCR-Based Detection of Plasmodium falciparum in Pregnant Women Using Dried Blood or Whole Blood Pellet Samples Processed through Different DNA Extraction Methods

    Saidi, Queen, Minja, D., Njau, J., Hansson, Helle Smedegaard, Kavishe, R. & Alifrangis, Michael, 2021, In: The American journal of tropical medicine and hygiene. 106, 3, p. 846-849 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2020
  21. Published

    Gene expression profiling of malaria parasites reveals common virulence gene expression in adult first-time infected patients and severe cases

    Wichers, J. S., Tonkin-Hill, G., Thye, T., Krumkamp, R., Kreuels, B., Strauss, J., Thien, H. V., Scholz, J. A. M., Hansson, H. S., Jensen, R. W., Turner, L., Lorenz, F-R., Schöllhorn, A., Bruchhaus, I., Tannich, E., Fendel, R., Otto, T. D., Lavstsen, T., Gilberger, T-W., Duffy, M. F. & 1 others, Bachmann, A., 2020, bioRxiv.

    Research output: Working paperPreprintResearch

  22. 2019
  23. Published

    First-in-human, randomized, double-blind clinical trial of differentially adjuvanted PAMVAC, a vaccine candidate to prevent pregnancy-associated malaria

    Mordmüller, B., Sulyok, M., Egger-Adam, D., Resende, M., de Jongh, W. A., Jensen, M. H., Smedegaard, H. H., Ditlev, S. B., Soegaard, M., Poulsen, L., Dyring, C., Calle, C. L., Knoblich, A., Ibáñez, J., Esen, M., Deloron, P., Ndam, N., Issifou, S., Houard, S., Howard, R. F. & 7 others, Reed, S. G., Leroy, O., Luty, A. J. F., Theander, Thor Grundtvig, Kremsner, P. G., Salanti, Ali & Nielsen, Morten Agertoug, 2019, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 69, 9, p. 1509-1516 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Temporal pattern of mutations in the knockdown resistance (kdr) gene of Aedes aegypti mosquitoes sampled from Southern Taiwan

    Biduda, S., Lin, C., Saleh, F., Konradsen, Flemming, Hansson, Helle Smedegaard, Schiøler, Karin Linda & Alifrangis, Michael, 2019, In: American Journal of Tropical Medicine and Hygiene. 101, 5, p. 973-975 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2015
  26. Published

    Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania

    Hansson, Helle Smedegaard, Turner, Louise, Møller, L., Wang, Christian William, Minja, D., Gesase, S., Mmbando, B., Bygbjerg, Ib Christian, Theander, Thor Grundtvig, Lusingu, J. P. A., Alifrangis, Michael & Lavstsen, Thomas, 2015, In: Malaria Journal. 14, 9 p., 474.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Polymorphisms in the Haem Oxygenase-1 promoter are not associated with severity of Plasmodium falciparum malaria in Ghanaian children

    Hansson, Helle Smedegaard, Sørensen, L. M., Balle, C., Goka, B. Q., Luzon, E., Nkrumah, F. N., Schousboe, M. L., Rodrigues, O. P., Bygbjerg, Ib Christian, Kurtzhals, Jørgen, Alifrangis, Michael & Hempel, C., 2015, In: Malaria Journal. 14, 9 p., 153.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2013
  29. Published

    Genotyping Plasmodium vivax isolates from the 2011 outbreak in Greece

    Spanakos, G., Alifrangis, Michael, Schousboe, M. L., Patsoula, E., Tegos, N., Hansson, Helle Smedegaard, Bygbjerg, Ib Christian, Vakalis, N. C., Tseroni, M., Kremastinou, J. & Hadjichristodoulou, C., 27 Dec 2013, In: Malaria Journal. 12, 1, p. 463

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Human genetic polymorphisms in the Knops blood group are not associated with a protective advantage against Plasmodium falciparum malaria in Southern Ghana

    Hansson, Helle Smedegaard, Kurtzhals, Jørgen, Goka, B. Q., Rodriques, O. P., Nkrumah, F. N., Theander, Thor Grundtvig, Bygbjerg, Ib Christian & Alifrangis, Michael, 7 Nov 2013, In: Malaria Journal. 12, 1, p. 400

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Rapid selection of Plasmodium falciparum chloroquine resistance transporter gene and multidrug resistance gene-1 haplotypes associated with past chloroquine and present artemether-lumefantrine use in Inhambane District, southern Mozambique

    Thomsen, T. T., Madsen, L. B., Hansson, Helle Smedegaard, Tomás, E. V. E., Charlwood, D., Bygbjerg, Ib Christian & Alifrangis, Michael, Mar 2013, In: American Journal of Tropical Medicine and Hygiene. 88, 3, p. 536-41 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2012
  33. Published

    The association between malaria parasitaemia, erythrocyte polymorphisms, malnutrition and anaemia in children less than 10 years in Senegal: a case control study

    Tine, R. C. K., Ndiaye, M., Hansson, Helle Smedegaard, Ndour, C. T., Faye, B., Alifrangis, Michael, Sylla, K., Ndiaye, J. L., Magnussen, Pascal, Bygbjerg, Ib Christian & Gaye, O., 2012, In: BMC Research Notes. 5, 1, p. 565 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    The association between malaria parasitemia, erythrocyte polymorphisms, malnutrition and anaemia in children less than 10 years in Senegal: a case control study

    Tine, R. C., Hansson, Helle Smedegaard, Ndiaye, M., Alifrangis, Michael, Faye, B., Ndour, C. T., Ndiaye, J. L., Magnussen, Pascal, Bygbjerg, Ib Christian & Gaye, O., 2012. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  35. 2006
  36. Published

    Coccidiose i danske lam: - to case studier

    Hempel Olsen, C., Petersen, H. H., Hansson, Helle Smedegaard, Thamsborg, Stig Milan & Maddox-Hyttel, C., 2006, In: Dansk Veterinærtidsskrift. 89, 8, p. 26-30

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 3509462