Thomas Lavstsen
Professor
- 2024
- Published
A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture
Andradi-Brown, C., Wichers-Misterek, J. S., von Thien, H., Höppner, Y. D., Scholz, J. A. M., Hansson, Helle Smedegaard, Hocke, Emma Filtenborg, Gilberger, T. W., Duffy, M. F., Lavstsen, Thomas, Baum, J., Otto, T. D., Cunnington, A. J. & Bachmann, A., 25 Jan 2024, In: eLife. 12, 38 p., RP87726.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Endothelial protein C receptor binding induces conformational changes to severe malaria-associated group A PfEMP1
Raghavan, Sai Sundar Rajan, Turner, Louise, Jensen, R. W., Johansen, Nicolai Tidemand, Jensen, D. S., Gourdon, Pontus Emanuel, Zhang, J., Wang, Y., Theander, Thor Grundtvig, Wang, Kaituo & Lavstsen, Thomas, 2023, In: Structure. 31, 10, p. 1174-1183.e4Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Analysis of var gene transcript patterns by quantitative real-time PCR
Bachmann, A. & Lavstsen, Thomas, 2022, Malaria Immunology: Targeting the Surface of Infected Erythrocytes. Humana Press, Vol. 2470. p. 149–171 23 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA
Raghavan, Sai Sundar Rajan, Dagil, Robert, Lopez-Perez, Mary, Conrad, J., Bassi, Maria Rosaria, Quintana Varon, Maria del Pilar, Choudhary, Swati, Gustavsson, Tobias, Wang, Y., Gourdon, Pontus Emanuel, Ofori, M. F., Christensen, S. B., Minja, D. T. R., Schmiegelow, Christentze, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Hviid, Lars, Salanti, Ali, Lavstsen, Thomas & Wang, Kaituo, 2022, In: PLoS Pathogens. 18, 11, e1010924.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mapping the cord blood transcriptome of pregnancies affected by early maternal anemia to identify signatures of fetal programming
Hatem, G., Hjort, Line, Asplund, O., Minja, D. T. R., Msemo, O. A., Møller, S. L., Lavstsen, Thomas, Grunnet, Louise Groth, Lusingu, J. P. A., Hansson, O., Christensen, Dirk Lund, Vaag, Allan, Artner, I., Theander, Thor Grundtvig, Groop, L., Schmiegelow, Christentze, Bygbjerg, Ib Christian & Prasad, R. B., 2022, In: The Journal of clinical endocrinology and metabolism. 107, 5, p. 1303–1316 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Seroprevalence of SARS-CoV-2 antibodies among children and adolescents recruited in a malariometric survey in north-eastern Tanzania July 2021
Lyimo, E., Fougeroux, Cyrielle Elyette, Malabeja, A., Mbwana, J., Hayuma, P. M., Liheluka, E., Turner, Louise, Gesase, S., Lavstsen, Thomas, Lusingu, J. P. A., Minja, D. T. R. & Wang, Christian William, 2022, In: BMC Infectious Diseases. 22, 846.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Varia: a tool for prediction, analysis and visualisation of variable genes
Mackenzie, G., Jensen, R. W., Lavstsen, Thomas & Otto, T. D., 2022, In: BMC Bioinformatics. 23, 13 p., 52.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Common virulence gene expression in adult first-time infected malaria patients and severe cases
Wichers, J. S., Tonkin-Hill, G., Thye, T., Krumkamp, R., Kreuels, B., Strauss, J., von Thien, H., Scholz, J. A. M., Smedegaard Hansson, H., Weisel Jensen, R., Turner, L., Lorenz, F-R., Schöllhorn, A., Bruchhaus, I., Tannich, E., Fendel, R., D Otto, T., Lavstsen, T., Gilberger, T. W., Duffy, M. & 1 others, , 2021, In: eLife. 10, e69040.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complement C1s cleaves PfEMP1 at interdomain conserved sites inhibiting Plasmodium falciparum cytoadherence
Azasi, Y., Low, L. M., Just, A. N., Raghavan, Sai Sundar Rajan, Wang, Christian William, Valenzuela-Leon, P., Alexandra Rowe, J., Smith, J. D., Lavstsen, Thomas, Turner, Louise, Calvo, E. & Miller, L. H., 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 22, e2104166118.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding
Wang, Kaituo, Dagil, Robert, Lavstsen, Thomas, Misra, S. K., Spliid, C. B., Wang, Y., Gustavsson, Tobias, Sandoval, D. R., Vidal-Calvo, E. E., Choudhary, Swati, Agerbæk, Mette Ørskov, Lindorff-Larsen, Kresten, Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sharp, J. S., Clausen, Thomas Mandel, Gourdon, Pontus Emanuel & Salanti, Ali, 2021, In: Nature Communications. 12, 1, 10 p., 2956.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 12224
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Plasmodium falciparum Plasmodium helical interspersed subtelomeric proteins contribute to cytoadherence and anchor P. falciparum erythrocyte membrane protein 1 to the host cell cytoskeleton
Research output: Contribution to journal › Journal article › Research › peer-review
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331
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Adhesion of Plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue: a novel model of placental malaria
Research output: Contribution to journal › Journal article › Research › peer-review
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309
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Structure-guided identification of a family of dual receptor-binding PfEMP1 that is associated with cerebral malaria
Research output: Contribution to journal › Journal article › Research › peer-review
Published