The efficacy of artemether in the treatment of Plasmodium falciparum malaria in Sudan

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Standard

The efficacy of artemether in the treatment of Plasmodium falciparum malaria in Sudan. / Elhassan, I M; Satti, G H; Ali, A E; Fadul, I; Elkhalifa, A A; Abedelrahim, A M; Ming, C; Theander, T G.

In: Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol. 87, No. 6, 1994, p. 685-6.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Elhassan, IM, Satti, GH, Ali, AE, Fadul, I, Elkhalifa, AA, Abedelrahim, AM, Ming, C & Theander, TG 1994, 'The efficacy of artemether in the treatment of Plasmodium falciparum malaria in Sudan', Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 87, no. 6, pp. 685-6.

APA

Elhassan, I. M., Satti, G. H., Ali, A. E., Fadul, I., Elkhalifa, A. A., Abedelrahim, A. M., Ming, C., & Theander, T. G. (1994). The efficacy of artemether in the treatment of Plasmodium falciparum malaria in Sudan. Transactions of the Royal Society of Tropical Medicine and Hygiene, 87(6), 685-6.

Vancouver

Elhassan IM, Satti GH, Ali AE, Fadul I, Elkhalifa AA, Abedelrahim AM et al. The efficacy of artemether in the treatment of Plasmodium falciparum malaria in Sudan. Transactions of the Royal Society of Tropical Medicine and Hygiene. 1994;87(6):685-6.

Author

Elhassan, I M ; Satti, G H ; Ali, A E ; Fadul, I ; Elkhalifa, A A ; Abedelrahim, A M ; Ming, C ; Theander, T G. / The efficacy of artemether in the treatment of Plasmodium falciparum malaria in Sudan. In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 1994 ; Vol. 87, No. 6. pp. 685-6.

Bibtex

@article{39bfb550a0db11dd86a6000ea68e967b,
title = "The efficacy of artemether in the treatment of Plasmodium falciparum malaria in Sudan",
abstract = "The efficacy of artemether (a qinghaosu derivative) administered intramuscularly for the treatment of Plasmodium falciparum malaria was compared to quinine in an open randomized trial including 54 patients in eastern Sudan, where chloroquine resistance is common. The artemether treatment (5 d intramuscular regimen) was effective and the drug was well tolerated. All patients had cleared the parasitaemia and were free of symptoms 48 h after initiation of treatment. The parasite clearance time was comparable in patients receiving artemether and quinine. No side effect was reported by patients receiving artemether. No recrudescence was seen in 21 patients treated with artemether who completed 28 d follow-up. In the quinine group 3 of 18 patients had recrudescences, or possibly reinfections, on days 14, 21 and 28.",
author = "Elhassan, {I M} and Satti, {G H} and Ali, {A E} and I Fadul and Elkhalifa, {A A} and Abedelrahim, {A M} and C Ming and Theander, {T G}",
note = "Keywords: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Follow-Up Studies; Humans; Injections, Intramuscular; Malaria, Falciparum; Middle Aged; Quinine; Recurrence; Sesquiterpenes; Time Factors",
year = "1994",
language = "English",
volume = "87",
pages = "685--6",
journal = "Transactions of the Royal Society of Tropical Medicine and Hygiene",
issn = "0035-9203",
publisher = "Oxford University Press",
number = "6",

}

RIS

TY - JOUR

T1 - The efficacy of artemether in the treatment of Plasmodium falciparum malaria in Sudan

AU - Elhassan, I M

AU - Satti, G H

AU - Ali, A E

AU - Fadul, I

AU - Elkhalifa, A A

AU - Abedelrahim, A M

AU - Ming, C

AU - Theander, T G

N1 - Keywords: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Follow-Up Studies; Humans; Injections, Intramuscular; Malaria, Falciparum; Middle Aged; Quinine; Recurrence; Sesquiterpenes; Time Factors

PY - 1994

Y1 - 1994

N2 - The efficacy of artemether (a qinghaosu derivative) administered intramuscularly for the treatment of Plasmodium falciparum malaria was compared to quinine in an open randomized trial including 54 patients in eastern Sudan, where chloroquine resistance is common. The artemether treatment (5 d intramuscular regimen) was effective and the drug was well tolerated. All patients had cleared the parasitaemia and were free of symptoms 48 h after initiation of treatment. The parasite clearance time was comparable in patients receiving artemether and quinine. No side effect was reported by patients receiving artemether. No recrudescence was seen in 21 patients treated with artemether who completed 28 d follow-up. In the quinine group 3 of 18 patients had recrudescences, or possibly reinfections, on days 14, 21 and 28.

AB - The efficacy of artemether (a qinghaosu derivative) administered intramuscularly for the treatment of Plasmodium falciparum malaria was compared to quinine in an open randomized trial including 54 patients in eastern Sudan, where chloroquine resistance is common. The artemether treatment (5 d intramuscular regimen) was effective and the drug was well tolerated. All patients had cleared the parasitaemia and were free of symptoms 48 h after initiation of treatment. The parasite clearance time was comparable in patients receiving artemether and quinine. No side effect was reported by patients receiving artemether. No recrudescence was seen in 21 patients treated with artemether who completed 28 d follow-up. In the quinine group 3 of 18 patients had recrudescences, or possibly reinfections, on days 14, 21 and 28.

M3 - Journal article

C2 - 8296377

VL - 87

SP - 685

EP - 686

JO - Transactions of the Royal Society of Tropical Medicine and Hygiene

JF - Transactions of the Royal Society of Tropical Medicine and Hygiene

SN - 0035-9203

IS - 6

ER -

ID: 6766782