Michael Theisen

Michael Theisen

Professor

Member of:

  • GLURP team


  1. 2021
  2. Published

    Exploratory analysis of the effect of helminth infection on the immunogenicity and efficacy of the asexual blood-stage malaria vaccine candidate GMZ2

    Nouatin, O., Mengue, J. B., Dejon-Agobé, J. C., Fendel, R., Ibáñez, J., Ngoa, U. A., Edoa, J. R., Adégbité, B. R., Honkpéhédji, Y. J., Zinsou, J. F., Hounkpatin, A. B., Moutairou, K., Homoet, A., Esen, M., Kreidenweiss, A., Hoffman, S. L., Theisen, M., Luty, A. J. F., Lell, B., Agnandji, S. T. & 5 others, Mombo-Ngoma, G., Ramharter, M., Kremsner, P., Mordmüller, B. & Adegnika, A. A., 2021, In: PLoS Neglected Tropical Diseases. 15, 6, 18 p., e0009361.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Extended follow-up of children in a phase2b trial of the GMZ2 malaria vaccine

    Dassah, S., Adu, B., Sirima, S. B., Mordmüller, B., Ngoa, U. A., Atuguba, F., Arthur, F. K. N., Mensah, B. A., Kaddumukasa, M., Bang, P., Kremsner, P. G., Mategula, D., Flach, C., Milligan, P. & Theisen, Michael, 2021, In: Vaccine. 39, 31, p. 4314-4319 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Identification of single-nucleotide polymorphisms in the mitochondrial genome and kelch 13 gene of Plasmodium falciparum in different geographical populations

    Nydahl, T. K., Ahorhorlu, S. Y., Ndiaye, M., Das, M. K., Hansson, Helle Smedegaard, Crespo Bravo, Marina, Wang, Christian William, Lusingu, J., Theisen, Michael, Singh, S. K., Singh, S., Campino, S., Lund, O., Roper, C. & Alifrangis, Michael, 2021, In: American Journal of Tropical Medicine and Hygiene. 105, 4, p. 1085-1092 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Neutrophils dominate in opsonic phagocytosis of P. falciparum blood-stage merozoites and protect against febrile malaria

    Garcia-Senosiain, A., Kana, Ikhlaq Hussain, Singh, S., Das, M. K., Dziegiel, Morten Hanefeld, Hertegonne, S., Adu, B. & Theisen, Michael, 2021, In: Communications Biology . 4, 984.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Preclinical development of a Pfs230-Pfs48/45 chimeric malaria transmission-blocking vaccine

    Singh, S. K., Plieskatt, J., Chourasia, B. K., Singh, V., Bengtsson, K. L., Reimer, J. M., van Daalen, R. C., Teelen, K., van de Vegte-Bolmer, M., van Gemert, G., Jore, M. M. & Theisen, Michael, 2021, In: npj Vaccines. 6, 11 p., 120.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Suitability of IgG responses to multiple Plasmodium falciparum antigens as markers of transmission intensity and pattern

    Kyei-Baafour, E., Oppong, M., Kusi, K. A., Frempong, A. F., Aculley, B., Arthur, F. K. N., Tiendrebeogo, R. W., Singh, S. K., Theisen, Michael, Kweku, M., Adu, B., Hviid, Lars & Ofori, M. F., 2021, In: PLoS ONE. 16, 4, e0249936.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2020
  9. Published

    Effect of immune regulatory pathways after immunization with GMZ2 malaria vaccine candidate in healthy lifelong malaria-exposed adults

    Nouatin, O., Ateba Ngoa, U., Ibáñez, J., Dejon-Agobe, J. C., Mordmüller, B., Edoa, J. R., Mougeni, F., Brückner, S., Bouyoukou Hounkpatin, A., Esen, M., Theisen, Michael, Moutairou, K., Hoffman, S. L., Issifou, S., Luty, A. J. F., Loembe, M. M., Agnandji, S. T., Lell, B., Kremsner, P. G. & Adegnika, A. A., 2 Jun 2020, In: Vaccine. 38, 27, p. 4263-4272 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Plasmodium falciparum Clag9-associated PfRhopH complex is involved in merozoite binding to human erythrocytes

    Chourasia, B. K., Deshmukh, A., Kaur, I., Paul, G., Panda, A., Rathore, S., Singh, S. K., Theisen, Michael, Mohmmed, A. & Malhotra, P., 2020, In: Infection and Immunity. 88, 2, e00504-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Evaluating the predictive performance of malaria antibodies and FCGR3B gene polymorphisms on Plasmodium falciparum infection outcome: a prospective cohort study

    Dwomoh, D., Adu, B., Dodoo, D., Theisen, Michael, Iddi, S. & Gerds, Thomas Alexander, 2020, In: Malaria Journal. 19, 1, 12 p., 307.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Microscopic and submicroscopic asymptomatic Plasmodium falciparum infections in Ghanaian children and protection against febrile malaria

    Adu, B., Issahaque, Q., Sarkodie-Addo, T., Kumordjie, S., Kyei-Baafour, E., Sinclear, C. K., Eyia-Ampah, S., Owusu-Yeboa, E., Theisen, Michael & Dodoo, D., 2020, In: Infection and Immunity. 88, 10, e00125-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Peripheral Merozoite Surface Proteins Are Targets of Naturally Acquired Immunity against Malaria in both India and Ghana

    Garcia-Senosiain, A., Kana, Ikhlaq Hussain, Singh, S. K., Chourasia, B. K., Das, M. K., Dodoo, D., Singh, S., Adu, B. & Theisen, Michael, 2020, In: Infection and Immunity. 88, 4, e00778-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Stage-specific Plasmodium falciparum immune responses in afebrile adults and children living in the Greater Accra Region of Ghana

    Acquah, F. K., Lo, A. C., Akyea-Mensah, K., Abagna, H. B., Faye, B., Theisen, Michael, Gyan, B. A. & Amoah, L. E., 2020, In: Malaria Journal. 19, 1, 11 p., 64.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The Plasmodium falciparum circumsporozoite protein produced in Lactococcus lactis is pure and stable

    Singh, S. K., Plieskatt, J., Chourasia, B. K., Singh, V., Bolscher, J. M., Dechering, K. J., Adu, B., López-Méndez, B., Kaviraj, S., Locke, E., King, C. R. & Theisen, Michael, 2020, In: Journal of Biological Chemistry. 295, 2, p. 403-414 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2019
  17. Published

    Plasmodium falciparum merozoite surface antigen-specific cytophilic IgG and control of malaria infection in a Beninese birth cohort

    Adamou, R., Dechavanne, C., Sadissou, I., d'Almeida, T., Bouraima, A., Sonon, P., Amoussa, R., Cottrell, G., Le Port, A., Theisen, M., Remarque, E. J., Longacre, S., Moutairou, K., Massougbodji, A., Luty, A. J. F., Nuel, G., Migot-Nabias, F., Sanni, A., Garcia, A., Milet, J. & 1 others, Courtin, D., 2019, In: Malaria Journal. 18, 11 p., 194.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Breadth of functional antibodies is associated with Plasmodium falciparum merozoite phagocytosis and protection against febrile malaria

    Kana, Ikhlaq Hussain, Singh, S. K., Garcia-Senosiain, A., Dodoo, D., Singh, S., Adu, B. & Theisen, Michael, 2019, In: The Journal of Infectious Diseases. 220, 2, p. 275-284 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Controlled human malaria infection of healthy adults with lifelong malaria exposure to assess safety, immunogenicity, and efficacy of the asexual blood stage malaria vaccine candidate GMZ2

    Dejon-Agobe, J. C., Ateba-Ngoa, U., Lalremruata, A., Homoet, A., Engelhorn, J., Nouatin, O. P., Edoa, J. R., Fernandes, J. F., Esen, M., Mouwenda, Y. D., Betouke Ongwe, E. M., Massinga-Loembe, M., Hoffman, S. L., Sim, B. K. L., Theisen, Michael, Kremsner, P. G., Adegnika, A. A., Lell, B. & Mordmüller, B., 2019, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 69, 8, p. 1377-1384 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Immunogenicity of a recombinant fusion construct composed of intrinsically unstructured, low polymorphic segments derived from merozoite surface protein 2 and trophozoite exported protein 1

    Tiendrebeogo, R. W., Spallek, R., Oehlmann, W., Singh, M., Theisen, Michael, Nebie, I., Moret, R., Roussilhon, C. & Corradin, G., 2019, In: Vaccine. 37, 36, p. 5332-5340 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Pfs230 and Pfs48/45 fusion proteins elicit strong transmission-blocking antibody responses against Plasmodium falciparum

    Singh, S. K., Thrane, Susan, Chourasia, B. K., Teelen, K., Graumans, W., Stoter, R., van Gemert, G., van de Vegte-Bolmer, M. G., Nielsen, Morten Agertoug, Salanti, Ali, Sander, Adam F. , Sauerwein, R. W., Jore, M. M. & Theisen, Michael, 2019, In: Frontiers in Immunology. 10, 1256.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The candidate blood-stage malaria vaccine P27A induces a robust humoral response in a fast track to the field Phase 1 trial in exposed and nonexposed volunteers

    Steiner-Monard, V., Kamaka, K., Karoui, O., Roethlisberger, S., Audran, R., Daubenberger, C., Fayet-Mello, A., Erdmann-Voisin, A., Felger, I., Geiger, K., Govender, L., Houard, S., Huber, E., Mayor, C., Mkindi, C., Portevin, D., Rusch, S., Schmidlin, S., Tiendrebeogo, R. W., Theisen, M. & 9 others, Thierry, A., Vallotton, L., Corradin, G., Leroy, O., Abdulla, S., Shekalaghe, S., Genton, B., Spertini, F. & Jongo, S. A., 2019, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 68, 3, p. 466-474 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2018
  24. Published

    Plasmodium falciparum MSP3 exists in a complex on the merozoite surface and generates antibody response during natural infection

    Deshmukh, A., Chourasia, B. K., Mehrotra, S., Kana, Ikhlaq Hussain, Paul, G., Panda, A., Kaur, I., Singh, S. K., Rathore, S., Das, A., Gupta, P., Kalamuddin, M., Gakhar, S. K., Mohmmed, A., Theisen, Michael & Malhotra, P., Aug 2018, In: Infection and Immunity. 86, 8, e00067-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity

    Stone, W. J. R., Campo, J. J., Ouédraogo, A. L., Meerstein-Kessel, L., Morlais, I., Da, D., Cohuet, A., Nsango, S., Sutherland, C. J., van de Vegte-Bolmer, M., Siebelink-Stoter, R., van Gemert, G-J., Graumans, W., Lanke, K., Shandling, A. D., Pablo, J. V., Teng, A. A., Jones, S., de Jong, R. M., Fabra-García, A. & 14 others, Bradley, J., Roeffen, W., Lasonder, E., Gremo, G., Schwarzer, E., Janse, C. J., Singh, S. K., Theisen, Michael, Felgner, P., Marti, M., Drakeley, C., Sauerwein, R., Bousema, T. & Jore, M. M., 8 Feb 2018, In: Nature Communications. 9, 1, 14 p., 558.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Assessment of the quality and quantity of naturally induced antibody responses to EBA175RIII-V in Ghanaian children living in two communities with varying malaria transmission patterns

    Abagna, H. B., Acquah, F. K., Okonu, R., Aryee, N. A., Theisen, Michael & Amoah, L. E., 8 Jan 2018, In: Malaria Journal. 17, 1, 11 p., 14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Dynamics of anti-MSP3 and Pfs230 antibody responses and multiplicity of infection in asymptomatic children from southern Ghana

    Amoah, L. E., Acquah, F. K., Ayanful-Torgby, R., Oppong, A., Abankwa, J., Obboh, E. K., Singh, S. K. & Theisen, Michael, 5 Jan 2018, In: Parasites & Vectors. 11, 1, 9 p., 13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Lactococcus lactis provides an efficient platform for production of disulfide-rich recombinant proteins from Plasmodium falciparum

    Singh, S. K., Tiendrebeogo, R. W., Chourasia, B. K., Kana, Ikhlaq Hussain, Singh, S. & Theisen, Michael, 2018, In: Microbial Cell Factories. 17, 13 p., 55.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Characterization of Plasmodium falciparum and Plasmodium vivax recent exposure in an area of significantly decreased transmission intensity in Central Vietnam

    Kattenberg, J. H., Erhart, A., Truong, M. H., Rovira-Vallbona, E., Vu, K. A. D., Nguyen, T. H. N., Nguyen, V. H., Nguyen, V. V., Bannister-Tyrrell, M., Theisen, Michael, Bennet, A., Lover, A. A., Tran, T. D., Nguyen, X. X. & Rosanas-Urgell, A., 2018, In: Malaria Journal. 17, 17 p., 180.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 10528769