Thor Grundtvig Theander
Professor
Centre for Medical Parasitology
Blegdamsvej 3, 2200 København N, Building: 07-11-17
CMP
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-11-TR4
Member of:
CMP-BIOENGINEERING
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Differential induction of functional IgG using the Plasmodium falciparum placental malaria vaccine candidate VAR2CSA
Pinto, V. V., Ditlev, S. B., Jensen, K. E., Resende, M., Dahlbäck, M., Andersen, G., Andersen, P., Theander, Thor Grundtvig, Salanti, Ali & Nielsen, Morten Agertoug, 1 Jan 2011, In: P L o S One. 6, 3, p. e17942Research output: Contribution to journal › Journal article › Research › peer-review
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Two-component vaccine consisting of virus-like particles displaying hepatitis C virus envelope protein 2 oligomers
Prentø, Jannick, Janitzek, C. M., Velázquez-Moctezuma, R., Sørensen, Andreas Holst Holmegaard, Jørgensen, T., Clemmensen, S., Soroka, V., Thrane, Susan, Theander, Thor Grundtvig, Nielsen, Morten Agertoug, Salanti, Ali, Bukh, Jens & Sander, Adam F. , 2022, In: npj Vaccines. 7, 148.Research output: Contribution to journal › Journal article › Research › peer-review
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Endothelial protein C receptor binding induces conformational changes to severe malaria-associated group A PfEMP1
Raghavan, Sai Sundar Rajan, Turner, Louise, Jensen, R. W., Johansen, Nicolai Tidemand, Jensen, D. S., Gourdon, Pontus Emanuel, Zhang, J., Wang, Y., Theander, Thor Grundtvig, Wang, Kaituo & Lavstsen, Thomas, 2023, In: Structure. 31, 10, p. 1174-1183.e4Research output: Contribution to journal › Journal article › Research › peer-review
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Acquisition of antibodies against endothelial protein C receptor-binding domains of Plasmodium falciparum erythrocyte membrane protein 1 in children with severe malaria
Rambhatla, J. S., Turner, Louise, Manning, L., Laman, M., Davis, T. M. E., Beeson, J. G., Mueller, I., Warrel, J., Theander, Thor Grundtvig, Lavstsen, Thomas & Rogerson, S. J., 2019, In: The Journal of Infectious Diseases. 219, 5, p. 808-818 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes - divide and conquer
Rask, T. S., Hansen, D. A., Theander, Thor Grundtvig, Gorm Pedersen, A. & Lavstsen, Thomas, 2010, In: P L o S Computational Biology. 6, 9Research output: Contribution to journal › Journal article › Research › peer-review
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Chondroitin sulphate A (CSA)-binding of single recombinant Duffy-binding-like domains is not restricted to Plasmodium falciparum Erythrocyte Membrane Protein 1 expressed by CSA-binding parasites
Resende, M., Ditlev, S. B., Nielsen, Morten Agertoug, Bodevin, S., Bruun, S., Pinto, V. V., Clausen, Henrik, Turner, Louise, Theander, Thor Grundtvig, Salanti, Ali & Dahlbäck, M., 2009, In: International Journal for Parasitology. 39, 11, p. 1195-204 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of glycosaminoglycan binding regions in the Plasmodium falciparum encoded placental sequestration ligand, VAR2CSA
Resende, M., Nielsen, Morten Agertoug, Dahlbäck, M., Ditlev, S. B., Andersen, P., Sander, A. F., Ndam, N. T., Theander, Thor Grundtvig & Salanti, Ali, 2008, In: Malaria Journal. 7, p. 104Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma antibodies from malaria-exposed pregnant women recognize variant surface antigens on Plasmodium falciparum-infected erythrocytes in a parity-dependent manner and block parasite adhesion to chondroitin sulfate A
Ricke, C. H., Staalsoe, T., Koram, K., Akanmori, B. D., Riley, E. M., Theander, Thor Grundtvig & Hviid, Lars, 2000, In: Journal of Immunology. 165, 6, p. 3309-16 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Malaria
Riley, E. M., Hviid, Lars & Theander, Thor Grundtvig, 1994, Parasitic infections and the immune system. San Diego: Academic Press, p. 119-143Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Malaria
Riley, E. M., Hviid, Lars & Theander, Thor Grundtvig, 22 Oct 2013, Parasitic Infections and the Immune System. Elsevier Science Inc., p. 119-143 25 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Detection of very low level Plasmodium falciparum infections using the nested polymerase chain reaction and a reassessment of the epidemiology of unstable malaria in Sudan
Roper, C., Elhassan, I. M., Hviid, Lars, Giha, H., Richardson, W., Babiker, H., Satti, G. M., Theander, Thor Grundtvig & Arnot, D. E., 1996, In: American Journal of Tropical Medicine and Hygiene. 54, 4, p. 325-31 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Seasonal changes in the Plasmodium falciparum population in individuals and their relationship to clinical malaria: a longitudinal study in a Sudanese village
Roper, C., Richardson, W., Elhassan, I. M., Giha, H., Hviid, Lars, Satti, G. M., Theander, Thor Grundtvig & Arnot, D. E., 1998, In: Parasitology. 116 ( Pt 6), p. 501-10 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential expression of var gene groups is associated with morbidity caused by Plasmodium falciparum infection in Tanzanian children
Rottmann, M., Lavstsen, Thomas, Mugasa, J. P., Kaestli, M., Jensen, Anja Ramstedt, Müller, D., Theander, Thor Grundtvig & Beck, H., 2006, In: Infection and Immunity. 74, 7, p. 3904-11 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein
Salanti, A., Clausen, T. M., Agerbæk, M. Ø., Al Nakouzi, N., Dahlbäck, M., Oo, H. Z., Lee, S., Gustavsson, T., Rich, J. R., Hedberg, B. J., Mao, Y., Barington, L., Pereira, M. A., LoBello, J., Endo, M., Fazli, L., Soden, J., Wang, C. K., Sander, A. F., Dagil, R. & 15 others, , 2015, In: Cancer Cell. 28, 4, p. 500-14 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A sub-family of common and highly conserved Plasmodium falciparum var genes
Salanti, Ali, Jensen, Anja Ramstedt, Zornig, H. D., Staalsoe, T., Joergensen, L., Nielsen, Morten Agertoug, Khattab, A., Arnot, D. E., Klinkert, M. Q., Hviid, Lars & Theander, Thor Grundtvig, 2002, In: Molecular and Biochemical Parasitology. 122, 1, p. 111-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evidence for the involvement of VAR2CSA in pregnancy-associated malaria
Salanti, Ali, Dahlbäck, M., Turner, Louise, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Magistrado, P., Jensen, Anja Ramstedt, Lavstsen, Thomas, Ofori, M. F., Marsh, K., Hviid, Lars & Theander, Thor Grundtvig, 2004, In: Journal of Experimental Medicine. 200, 9, p. 1197-203 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria
Salanti, Ali, Staalsoe, T., Lavstsen, Thomas, Jensen, Anja Ramstedt, Sowa, M. P. K., Arnot, D. E., Hviid, Lars & Theander, Thor Grundtvig, 2003, In: Molecular Microbiology. 49, 1, p. 179-91 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Several domains from VAR2CSA can induce Plasmodium falciparum adhesion-blocking antibodies
Salanti, Ali, Resende, M., Ditlev, S. B., Pinto, V. V., Dahlbäck, M., Andersen, G., Manczak, T., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2010, In: Malaria Journal. 9, 1, p. 11Research output: Contribution to journal › Journal article › Research › peer-review
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Optimization of rVAR2-based isolation of cancer cells in blood for building a robust assay for clinical detection of circulating tumor cells
Sand, Nicolai Tue, Petersen, T. B., Bang-Christensen, S. R., Ahrens, T. D., Løppke, Caroline Bang, Jørgensen, A. M., Gustavsson, Tobias, Choudhary, Swati, Theander, Thor Grundtvig, Salanti, Ali & Agerbæk, Mette Ørskov, 2020, In: International Journal of Molecular Sciences . 21, 7, 2401.Research output: Contribution to journal › Journal article › Research › peer-review
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Positive selection of Plasmodium falciparum parasites with multiple var2csa-type PfEMP1 genes during the course of infection in pregnant women
Sander, A. F., Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Leke, R. G. F., Lo, Y. Y., Bobbili, N., Arnot, D. E. & Taylor, D. W., 2011, In: Journal of Infectious Diseases. 203, 11, p. 1679-85 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Factors associated with and causes of perinatal mortality in northeastern Tanzania
Schmiegelow, Christentze, Minja, D., Oesterholt, M., Pehrson, Caroline, Suhrs, H. E., Boström, S., Lemnge, M., Magistrado, P., Rasch, V., Lusingu, J., Theander, Thor Grundtvig & Nielsen, B. B., Sep 2012, In: Acta Obstetrica et Gynecologica. 91, 9, p. 1061-1068 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Development of a fetal weight chart using serial trans-abdominal ultrasound in an East African population: A longitudinal observational study
Schmiegelow, Christentze, Scheike, Thomas, Oesterholt, M., Minja, D., Pehrson, Caroline, Magistrado, P., Lemnge, M., Rasch, V., Lusingu, J., Theander, Thor Grundtvig & Nielsen, B. B., 2012, In: P L o S One. 7, 9, e44773.Research output: Contribution to journal › Journal article › Research › peer-review
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Malaria and Fetal Growth Alterations in the 3(rd) Trimester of Pregnancy: A Longitudinal Ultrasound Study
Schmiegelow, Christentze, Minja, D., Oesterholt, M., Pehrson, Caroline, Suhrs, H. E., Boström, S., Lemnge, M., Magistrado, P., Rasch, V., Nielsen, B. B., Lusingu, J. & Theander, Thor Grundtvig, 2013, In: P L o S One. 8, 1, p. e53794Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum infection early in pregnancy has profound consequences for fetal growth
Schmiegelow, Christentze, Matondo, S., Minja, D. T. R., Resende, M., Pehrson, Caroline, Nielsen, B. B., Olomi, R., Nielsen, Morten Agertoug, Deloron, P., Salanti, Ali, Lusingu, J. & Theander, Thor Grundtvig, 19 Dec 2017, In: The Journal of Infectious Diseases. 216, 12, p. 1601-1610 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Factors associated with and causes of perinatal mortality in northeastern Tanzania
Schmiegelow, Christentze, Minja, D., Oesterholt, M., Pehrson, C., Suhrs, H. E., Boström, S., Lemnge, M., Magistrado, P., Rasch, V., Lusingu, J., Theander, Thor Grundtvig & Nielsen, B. B., 2012, In: Acta Obstetricia et Gynecologica Scandinavica. 91, 9, p. 1061-1068 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anaemia in the first trimester and poor physiological plasma expansion during pregnancy negatively impact foetal weight and newborn anthropometrics: An observational cohort study in Tanzania
Schmiegelow, Christentze, Møller, S. L., Yde, A. M., Nielsen, B. B., Hjort, Line, Theander, Thor Grundtvig, Lusingu, J. P. A., Minja, D. T. R. & Bygbjerg, Ib Christian, 2024, In: Tropical Medicine & International Health. 29, 3, p. 243-255 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Preconceptional factors associated with haemoglobin concentration in early pregnancy: a community-based cohort study in rural northeastern Tanzania
Schmiegelow, Christentze, Msemo, O. A., Møller, S. L., Nielsen, B. B., Paulsen, C. B., Ødum, L., Theander, Thor Grundtvig, Kavishe, R. A., Lusingu, J. P. A., Minja, D. T. & Bygbjerg, Ib Christian, 2019, In: Tropical Medicine and International Health. 24, 5, p. 596-607 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Leishmania donovani: an in vitro study of antimony-resistant amphotericin B-sensitive isolates
Sharief, A. H., Gasim Khalil, E. A., Theander, Thor Grundtvig, Kharazmi, A., Omer, S. A. & Ibrahim, M. E., 2006, In: Experimental Parasitology. 114, 4, p. 247-52 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Programmed transcription of the var gene family, but not of stevor, in Plasmodium falciparum gametocytes
Sharp, S., Lavstsen, Thomas, Fivelman, Q. L., Saeed, M., McRobert, L., Templeton, T. J., Jensen, Anja Ramstedt, Baker, D. A., Theander, Thor Grundtvig & Sutherland, C. J., 2006, In: Eukaryotic Cell. 5, 8, p. 1206-14 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Improving the malaria transmission-blocking activity of a Plasmodium falciparum 48/45 based vaccine antigen by SpyTag/SpyCatcher mediated virus-like display
Singh, S. K., Thrane, Susan, Janitzek, C. M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Theisen, Michael, Salanti, Ali & Sander, Adam F. , 2017, In: Vaccine. 35, 30, p. 3726-3732 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bispecific T cell-engager targeting oncofetal chondroitin sulfate induces complete tumor regression and protective immune memory in mice
Skeltved, Nanna, Nordmaj, Mie Anemone, Pagh-Berendtsen, Nicolai, Dagil, Robert, Stormer, E. M. R., Al-Nakouzi, N., Jiang, K., Aicher, A., Heeschen, C., Gustavsson, Tobias, Choudhary, Swati, Gögenur, Ismail, Christensen, Jan Pravsgaard, Theander, Thor Grundtvig, Daugaard, M., Salanti, Ali & Nielsen, Morten Agertoug, 2023, In: Journal of Experimental & Clinical Cancer Research. 42, 16 p., 106.Research output: Contribution to journal › Journal article › Research › peer-review
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First-in-human use of a modular capsid virus-like vaccine platform: An open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2
Smit, M. J., Sander, A. F., Ariaans, M. B. P. A., Fougeroux, C., Heinzel, C., Fendel, R., Esen, M., Kremsner, P. G., Ter Heine, R., Wertheim, H. F., Idorn, M., Paludan, S. R., Underwood, A. P., Binderup, A., Ramirez, S., Bukh, J., Soegaard, M., Erdogan, S. M., Gustavsson, T., Clemmensen, S. & 14 others, , 2023, In: The Lancet Microbe. 4, 3, p. e140-e148Research output: Contribution to journal › Journal article › Research › peer-review
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The specificity of the malarial VAR2CSA protein for chondroitin sulfate depends on 4-O-sulfation and ligand accessibility
Spliid, C. B., Toledo, A. G., Sanderson, P., Mao, Y., Gatto, F., Gustavsson, Tobias, Choudhary, Swati, Saldanha, A. L., Vogelsang, R. P., Gögenur, Ismail, Theander, Thor Grundtvig, Leach, F. E., Amster, I. J., Esko, J. D., Salanti, Ali & Clausen, Thomas Mandel, 2021, In: The Journal of Biological Chemistry. 297, 6, 15 p., 101391.Research output: Contribution to journal › Journal article › Research › peer-review
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Detection of antibodies to variant antigens on Plasmodium falciparum-infected erythrocytes by flow cytometry
Staalsoe, T., Giha, H. A., Dodoo, D., Theander, Thor Grundtvig & Hviid, Lars, 1999, In: Cytometry. Part B: Clinical Cytometry. 35, 4, p. 329-36 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Novel Plasmodium falciparum malaria vaccines: evidence-based searching for variant surface antigens as candidates for vaccination against pregnancy-associated malaria
Staalsoe, T., Jensen, Anja Ramstedt, Theander, Thor Grundtvig & Hviid, Lars, 2002, In: Immunology Letters. 84, 2, p. 133-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro selection of Plasmodium falciparum 3D7 for expression of variant surface antigens associated with severe malaria in African children
Staalsoe, T., Nielsen, Morten Agertoug, Vestergaard, L. S., Jensen, Anja Ramstedt, Theander, Thor Grundtvig & Hviid, Lars, 2003, In: Parasite Immunology. 25, 8-9, p. 421-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vivo switching between variant surface antigens in human Plasmodium falciparum infection
Staalsoe, T., Hamad, A. A., Hviid, Lars, Elhassan, I. M., Arnot, D. E. & Theander, Thor Grundtvig, 2002, In: Journal of Infectious Diseases. 186, 5, p. 719-22 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibody reactivity to conserved linear epitopes of Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1)
Staalsø, T., Khalil, E. A., Elhassan, I. M., Zijlstra, E. E., Elhassan, A. M., Giha, H. A., Theander, Thor Grundtvig & Jakobsen, P. H., 1998, In: Immunology Letters. 60, 2-3, p. 121-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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IgG responses to Anopheles gambiae salivary antigen gSG6 detect variation in exposure to malaria vectors and disease risk
Stone, W., Bousema, T., Jones, S., Gesase, S., Hashim, R., Gosling, R., Carneiro, I., Chandramohan, D., Theander, Thor Grundtvig, Ronca, R., Modiano, D., Arcà, B. & Drakeley, C., 2012, In: P L o S One. 7, 6, p. e40170Research output: Contribution to journal › Journal article › Research › peer-review
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Proliferation induced by Plasmodium falciparum antigen and interleukin-2 production by lymphocytes isolated from malaria-immune individuals
Theander, Thor Grundtvig, Bygbjerg, Ib Christian, Jepsen, S., Svenson, M., Kharazmi, A., Larsen, P. B. & Bendtzen, K., 1986, In: Infection and Immunity. 53, 1, p. 221-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of human lymphocyte proliferation and cleavage of interleukin-2 by Pseudomonas aeruginosa proteases
Theander, Thor Grundtvig, Kharazmi, A., Pedersen, Bente Klarlund, Christensen, L. D., Tvede, N., Poulsen, Lars K., Ødum, Niels, Svenson, M. & Bendtzen, K., 1988, In: Infection and Immunity. 56, 7, p. 1673-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Enhancement of human natural cytotoxicity by Plasmodium falciparum antigen activated lymphocytes
Theander, Thor Grundtvig, Pedersen, Bente Klarlund, Bygbjerg, Ib Christian, Jepsen, S., Larsen, P. B. & Kharazmi, A., 1987, In: Acta Tropica. 44, 4, p. 415-22 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Low parasite specific T cell response in clinically immune individuals with low grade Plasmodium falciparum parasitaemia
Theander, Thor Grundtvig, Bygbjerg, Ib Christian, Jacobsen, L., Jepsen, S., Larsen, P. B. & Kharazmi, A., 1986, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 80, 6, p. 1000-1 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Suppression of parasite-specific response in Plasmodium falciparum malaria. A longitudinal study of blood mononuclear cell proliferation and subset composition
Theander, Thor Grundtvig, Bygbjerg, Ib Christian, Andersen, B. J., Jepsen, S., Kharazmi, A. & Ødum, Niels, 1986, In: Scandinavian Journal of Immunology. 24, 1, p. 73-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Defence mechanisms and immune evasion in the interplay between the humane immune system and Plasmodium falciparum
Theander, Thor Grundtvig, 1992, In: Danish Medical Bulletin. 39, 1, p. 49-63 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cell-mediated immunity to Plasmodium falciparum infection: evidence against the involvement of cytotoxic lymphocytes
Theander, Thor Grundtvig, Andersen, B. J., Pedersen, B. K., Jepsen, S., Bygbjerg, Ib Christian, Hviid, Lars, Larsen, P. B. & Kharazmi, A., 1988, In: Scandinavian Journal of Immunology. 28, 1, p. 105-11 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Unstable malaria in Sudan: the influence of the dry season. Malaria in areas of unstable and seasonal transmission. Lessons from Daraweesh
Theander, Thor Grundtvig, 1999, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 92, 6, p. 589-92 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of human lymphocyte proliferative response by serum from Plasmodium falciparum infected patients
Theander, Thor Grundtvig, Svenson, M., Bygbjerg, Ib Christian, Kharazmi, A., Jepsen, S., Andersen, B. J. & Larsen, P. B., 1987, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 95, 6, p. 257-63 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human T-cell recognition of synthetic peptides representing conserved and variant sequences from the merozoite surface protein 2 of Plasmodium falciparum
Theander, Thor Grundtvig, Hviid, Lars, Dodoo, D., Afari, E. A., Jensen, J. B. & Rzepczyk, C. M., 1997, In: Immunology Letters. 58, 1, p. 1-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reduced cellular immune reactivity in healthy individuals during the malaria transmission season
Theander, Thor Grundtvig, Hviid, Lars, Abu-Zeid, Y. A., Abdulhadi, N. H., Saeed, B. O., Jakobsen, P. H., Reimert, C. M., Jepsen, S., Bayoumi, R. A. & Jensen, J. B., 1990, In: Immunology Letters. 25, 1-3, p. 237-42 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Real-time and label free determination of ligand binding-kinetics to primary cancer tissue specimens; a novel tool for the assessment of biomarker targeting
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Bacterial superglue enables easy development of efficient virus-like particle based vaccines
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Placental sequestration of Plasmodium falciparum malaria parasites is mediated by the interaction between VAR2CSA and chondroitin sulfate A on syndecan-1
Research output: Contribution to journal › Journal article › Research › peer-review
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