Michael Theisen
Professor
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Development and evaluation of a multiplex screening assay for Plasmodium falciparum exposure
Jepsen, M. P. G., Röser, D., Christiansen, M., Larsen, S. O., Cavanagh, D. R., Dhanasarnsombut, K., Bygbjerg, Ib Christian, Dodoo, D., Remarque, E. J., Dziegiel, Morten Hanefeld, Jepsen, S., Mordmüller, B. & Theisen, Michael, 2012, In: Journal of Immunological Methods. 384, 1-2, p. 62-70 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Flow cytometric readout based on Mitotracker Red CMXRos staining of live asexual blood stage malarial parasites reliably assesses antibody dependent cellular inhibition
Jogdand, P. S., Singh, S. K., Christiansen, M., Dziegiel, Morten Hanefeld, Singh, S. & Theisen, Michael, 2012, In: Malaria Journal. 11, 1, p. 235Research output: Contribution to journal › Journal article › Research › peer-review
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Naturally acquired antibody responses to recombinant Pfs230 and Pfs48/45 transmission blocking vaccine candidates
Jones, S., Grignard, L., Nebie, I., Chilongola, J., Dodoo, D., Sauerwein, R., Theisen, Michael, Roeffen, W., Singh, S. K., Singh, R. K., Singh, S., Kyei-Baafour, E., Tetteh, K., Drakeley, C. & Bousema, T., Jul 2015, In: Journal of Infection. 71, 1, p. 117-27 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Breadth of functional antibodies is associated with Plasmodium falciparum merozoite phagocytosis and protection against febrile malaria
Kana, Ikhlaq Hussain, Singh, S. K., Garcia-Senosiain, A., Dodoo, D., Singh, S., Adu, B. & Theisen, Michael, 2019, In: The Journal of Infectious Diseases. 220, 2, p. 275-284 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Naturally acquired antibodies target the glutamate-rich protein on intact merozoites and predict protection against febrile malaria
Kana, Ikhlaq Hussain, Adu, B., Tiendrebeogo, R. W., Singh, S. K., Dodoo, D. & Theisen, Michael, 15 Feb 2017, In: The Journal of Infectious Diseases. 215, 4, p. 623-630 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cytophilic Antibodies Against Key Plasmodium falciparum Blood Stage Antigens Contribute to Protection Against Clinical Malaria in a High Transmission Region of Eastern India
Kana, Ikhlaq Hussain, Garcia Senosiain, A., Singh, S., Tiendrebeogo, R. W., Chourasia, B., Malhotra, P., Sharma, S. K., Das, M. K., Singh, S., Adu, B. & Theisen, Michael, 2018, In: The Journal of Infectious Diseases. 218, 6, p. 956-965Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of Plasmodium falciparum and Plasmodium vivax recent exposure in an area of significantly decreased transmission intensity in Central Vietnam
Kattenberg, J. H., Erhart, A., Truong, M. H., Rovira-Vallbona, E., Vu, K. A. D., Nguyen, T. H. N., Nguyen, V. H., Nguyen, V. V., Bannister-Tyrrell, M., Theisen, Michael, Bennet, A., Lover, A. A., Tran, T. D., Nguyen, X. X. & Rosanas-Urgell, A., 2018, In: Malaria Journal. 17, 17 p., 180.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum AMA1 and CSP antigen diversity in parasite isolates from southern Ghana
Kusi, K. A., Amoah, L. E., Acquah, F. K., Ennuson, N. A., Frempong, A. F., Ofori, Ebenezer Addo, Akyea-Mensah, K., Kyei-Baafour, E., Osei, F., Frimpong, A., Singh, S. K., Theisen, Michael, Remarque, E. J., Faber, B. W., Belmonte, M., Ganeshan, H., Huang, J., Villasante, E. & Sedegah, M., 2024, In: Frontiers in Cellular and Infection Microbiology. 14, 14 p., 1375249.Research output: Contribution to journal › Journal article › Research › peer-review
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Suitability of IgG responses to multiple Plasmodium falciparum antigens as markers of transmission intensity and pattern
Kyei-Baafour, E., Oppong, M., Kusi, K. A., Frempong, A. F., Aculley, B., Arthur, F. K. N., Tiendrebeogo, R. W., Singh, S. K., Theisen, Michael, Kweku, M., Adu, B., Hviid, Lars & Ofori, M. F., 2021, In: PLoS ONE. 16, 4, e0249936.Research output: Contribution to journal › Journal article › Research › peer-review
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High opsonic phagocytosis activity and growth inhibition of merozoites are associated with RON4 antibody levels and protect against febrile malaria in Ghanaian children
Kyei-Baafour, E., Kusi, K. A., Arthur, F. K. N., Tiendrebeogo, R. W., Owusu-Yeboa, E., Singh, S. K., Friedrich, S., Gerds, Thomas Alexander, Dodoo, D., Theisen, Michael & Adu, B., 2023, In: Frontiers in Immunology. 14, 10 p., 1161301.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of Immunoglobulin G3 Hinge Region Length Polymorphism With Cerebral Malaria in Ghanaian Children
Kyei-Baafour, E., Kusi, K. A., Arthur, F. K. N., Sarkodie-Addo, T., Theisen, Michael, Dodoo, D. & Adu, B., 2022, In: The Journal of Infectious Diseases. 225, 10, p. 1786-1790 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A synthetic TLR4 agonist formulated in an emulsion enhances humoral and Type 1 cellular immune responses against GMZ2 - A GLURP-MSP3 fusion protein malaria vaccine candidate
Lousada-Dietrich, S., Jogdand, P. S., Jepsen, S., Valadão Vaz dos Santos Pinto, V. M., Ditlev, S. B., Christiansen, M., Larsen, S. O., Fox, C. B., Raman, V. S., Howard, R. F., Vedvick, T. S., Ireton, G., Carter, D., Reed, S. G. & Theisen, Michael, 12 Apr 2011, In: Vaccine. 29, 17, p. 3284-92 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Humoral immune response to Plasmodium falciparum vaccine candidate GMZ2 and its components in populations naturally exposed to seasonal malaria in Ethiopia
Mamo, H., Esen, M., Ajua, A., Theisen, Michael, Mordmüller, B. & Petros, B., 2013, In: Malaria Journal. 12, 1, p. 51Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of the OspE determinants involved in binding of factor H and OspE-targeting antibodies elicited during Borrelia burgdorferi infection in mice
Metts, M. S., McDowell, J. V., Theisen, Michael, Hansen, Paul Robert & Marconi, R. T., 1 Jun 2003, In: Infection and Immunity. 71, 6, p. 3587-3596 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Efficacy of the GMZ2 malaria vaccine in African children
Milligan, P., Flach, C. & Theisen, Michael, 5 Jan 2017, In: Vaccine. 35, 2, p. 202 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Expression, Purification and Characterization of GMZ2'.10C, a Complex Disulphide-Bonded Fusion Protein Vaccine Candidate against the Asexual and Sexual Life-Stages of the Malaria-Causing Plasmodium falciparum Parasite
Mistarz, U. H., Singh, S. K., Nguyen, T. T. T. N., Roeffen, W., Yang, F., Lissau, C., Madsen, S. M., Vrang, A., Tiendrebeogo, R. W., Kana, Ikhlaq Hussain, Sauerwein, R. W., Theisen, Michael & Rand, Kasper Dyrberg, 1 Sep 2017, In: Pharmaceutical Research. 34, 9, p. 1970-1983 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Atypical and classical memory B cells produce Plasmodium falciparum neutralizing antibodies
Muellenbeck, M. F., Ueberheide, B., Amulic, B., Epp, A., Fenyo, D., Busse, C. E., Esen, M., Theisen, Michael, Mordmüller, B. & Wardemann, H., 11 Feb 2013, In: Journal of Experimental Medicine. 210, 2, p. 389-99 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A threshold concentration of anti-merozoite antibodies is required for protection from clinical episodes of malaria
Murungi, L. M., Kamuyu, G., Lowe, B., Bejon, P., Theisen, Michael, Kinyanjui, S. M., Marsh, K. & Osier, F. H. A., 20 Aug 2013, In: Vaccine. 31, 37, p. 3936-42 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Production and purification of Plasmodium circumsporozoite protein in Lactococcus lactis
Naghizadeh, Mohammad, Singh, S. K., Plieskatt, J., Ofori, Ebenezer Addo & Theisen, Michael, 2024, Recombinant Glycoproteins: Methods and Protocols. Bradfute, S. B. (ed.). Humana Press, p. 109-121 13 p. (Methods in molecular biology (Clifton, N.J.), Vol. 27521).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Potential Impact of Seasonal Malaria Chemoprevention on the Acquisition of Antibodies Against Glutamate-Rich Protein and Apical Membrane Antigen 1 in Children Living in Southern Senegal
Ndiaye, M., Sylla, K., Sow, D., Tine, R., Faye, B., Ndiaye, J. L., Dieng, Y., Lo, A. C., Abiola, A., Cisse, B., Ndiaye, D., Theisen, Michael, Gaye, O. & Alifrangis, Michael, 2015, In: American Journal of Tropical Medicine and Hygiene. 93, 4, p. 798-800 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Exploratory analysis of the effect of helminth infection on the immunogenicity and efficacy of the asexual blood-stage malaria vaccine candidate GMZ2
Nouatin, O., Mengue, J. B., Dejon-Agobé, J. C., Fendel, R., Ibáñez, J., Ngoa, U. A., Edoa, J. R., Adégbité, B. R., Honkpéhédji, Y. J., Zinsou, J. F., Hounkpatin, A. B., Moutairou, K., Homoet, A., Esen, M., Kreidenweiss, A., Hoffman, S. L., Theisen, M., Luty, A. J. F., Lell, B., Agnandji, S. T. & 5 others, , 2021, In: PLoS Neglected Tropical Diseases. 15, 6, 18 p., e0009361.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of immune regulatory pathways after immunization with GMZ2 malaria vaccine candidate in healthy lifelong malaria-exposed adults
Nouatin, O., Ateba Ngoa, U., Ibáñez, J., Dejon-Agobe, J. C., Mordmüller, B., Edoa, J. R., Mougeni, F., Brückner, S., Bouyoukou Hounkpatin, A., Esen, M., Theisen, Michael, Moutairou, K., Hoffman, S. L., Issifou, S., Luty, A. J. F., Loembe, M. M., Agnandji, S. T., Lell, B., Kremsner, P. G. & Adegnika, A. A., 2 Jun 2020, In: Vaccine. 38, 27, p. 4263-4272 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cellular and antibody response in GMZ2-vaccinated Gabonese volunteers in a controlled human malaria infection trial
Nouatin, O., Ibáñez, J., Fendel, R., Ngoa, U. A., Lorenz, F., Dejon-Agobé, J., Edoa, J. R., Flügge, J., Brückner, S., Esen, M., Theisen, Michael, Hoffman, S. L., Moutairou, K., Luty, A. J. F., Lell, B., Kremsner, P. G., Adegnika, A. A. & Mordmüller, B., 2022, In: Malaria Journal. 21, 1, p. 191Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of single-nucleotide polymorphisms in the mitochondrial genome and kelch 13 gene of Plasmodium falciparum in different geographical populations
Nydahl, T. K., Ahorhorlu, S. Y., Ndiaye, M., Das, M. K., Hansson, Helle Smedegaard, Crespo Bravo, Marina, Wang, Christian William, Lusingu, J., Theisen, Michael, Singh, S. K., Singh, S., Campino, S., Lund, O., Roper, C. & Alifrangis, Michael, 2021, In: American Journal of Tropical Medicine and Hygiene. 105, 4, p. 1085-1092 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anti-gametocyte antigen humoral immunity and gametocytemia during treatment of uncomplicated falciparum malaria: A multi-national study
O'Flaherty, K., Chan, J-A., Cutts, J. C., Zaloumis, S. G., Ashley, E. A., Phyo, A. P., Drew, D. R., Dondorp, A. M., Day, N. P., Dhorda, M., Fairhurst, R. M., Lim, P., Amaratunga, C., Pukrittayakamee, S., Hien, T. T., Htut, Y., Mayxay, M., Faiz, M. A., Mokuolu, O. A., Onyamboko, M. A. & 9 others, , 2022, In: Frontiers in Cellular and Infection Microbiology. 12, p. 804470Research output: Contribution to journal › Journal article › Research › peer-review
ID: 10528769
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Natural antibody responses to Plasmodium falciparum MSP3 and GLURP(R0) antigens are associated with low parasite densities in malaria patients living in the Central Region of Ghana
Research output: Contribution to journal › Journal article › Research › peer-review
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229
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Construct design, production, and characterization of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine
Research output: Contribution to journal › Journal article › Research › peer-review
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209
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Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity
Research output: Contribution to journal › Journal article › Research › peer-review
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