- 2024
- Published
Clinical formulation development of Plasmodium falciparum malaria vaccine candidates based on Pfs48/45, Pfs230, and PfCSP
Plieskatt, J., Bang, P., Wood, G. K., Naghizadeh, Mohammad, Singh, S. K., Jore, M. M. & Theisen, Michael, 16 Mar 2024, In: Vaccine. p. 1980-1992Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Pfs48/45-based vaccine to block Plasmodium falciparum transmission: phase 1, open-label, clinical trial
Alkema, M., Smit, M. J., Marin-Mogollon, C., Totté, K., Teelen, K., van Gemert, G. J., van de Vegte-Bolmer, M., Mordmüller, B. G., Reimer, J. M., Lövgren-Bengtsson, K. L., Sauerwein, R. W., Bousema, T., Plieskatt, J., Theisen, Michael, Jore, M. M. & McCall, M. B. B., 2024, In: BMC Medicine. 22, 1, 12 p., 170.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A randomized first-in-human phase I trial of differentially adjuvanted Pfs48/45 malaria vaccines in Burkinabé adults
Tiono, A. B., Plieskatt, J. L., Ouedraogo, A., Soulama, B. I., Miura, K., Bougouma, E. C., Naghizadeh, M., Barry, A., Yaro, J. B. B., Ezinmegnon, S., Henry, N., Ofori, E. A., Adu, B., Singh, S. K., Konkobo, A., Lövgren Bengtsson, K., Diarra, A., Carnrot, C., Reimer, J. M., Ouedraogo, A. & 6 others, , 2024, In: The Journal of Clinical Investigation. 134, 7, 15 p., e175707.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Production and purification of Plasmodium circumsporozoite protein in Lactococcus lactis
Naghizadeh, Mohammad, Singh, S. K., Plieskatt, J., Ofori, Ebenezer Addo & Theisen, Michael, 2024, Recombinant Glycoproteins: Methods and Protocols. Bradfute, S. B. (ed.). Humana Press, p. 109-121 13 p. (Methods in molecular biology (Clifton, N.J.), Vol. 27521).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 2023
- Published
B-Cell epitope mapping of the Plasmodium falciparum malaria vaccine candidate GMZ2.6c in a naturally exposed population of the Brazilian Amazon
Baptista, B. D. O., Souza, A. B. L. D., Oliveira, L. S. D., Souza, H. A. D. S. D., Barros, J. P. D., Queiroz, L. T. D., Souza, R. M. D., Amoah, L. E., Singh, S. K., Theisen, Michael, Rodrigues-da-Silva, R. N., Riccio, E. K. P., Totino, P. R. R., Lima-Junior, J. D. C., Daniel-Ribeiro, C. T. & Pratt-Riccio, L. R., 2023, In: Vaccines. 11, 2, 446.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cloning and recombinant protein expression in Lactococcus lactis
Singh, S. K., Naghizadeh, Mohammad, Plieskatt, J., Singh, S. & Theisen, Michael, 2023, Advanced Methods in Structural Biology. Sousa, Â. & Passarinha, L. (eds.). Humana Press, p. 3-20 18 p. (Methods in Molecular Biology, Vol. 2652).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
High opsonic phagocytosis activity and growth inhibition of merozoites are associated with RON4 antibody levels and protect against febrile malaria in Ghanaian children
Kyei-Baafour, E., Kusi, K. A., Arthur, F. K. N., Tiendrebeogo, R. W., Owusu-Yeboa, E., Singh, S. K., Friedrich, S., Gerds, Thomas Alexander, Dodoo, D., Theisen, Michael & Adu, B., 2023, In: Frontiers in Immunology. 14, 10 p., 1161301.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human blood neutrophils generate ROS through FcγR-signaling to mediate protection against febrile P. falciparum malaria
Ofori, Ebenezer Addo, Garcia-Senosiain, A., Naghizadeh, Mohammad, Kana, Ikhlaq Hussain, Dziegiel, Morten Hanefeld, Adu, B., Singh, S. & Theisen, Michael, 2023, In: Communications Biology . 6, 743.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serological evaluation of risk factors for exposure to malaria in a pre-elimination setting in Malaysian Borneo
Byrne, I., William, T., Chua, T. H., Patterson, C., Hall, T., Tan, M., Chitnis, C., Adams, J., Singh, S. K., Grignard, L., Tetteh, K. K. A., Fornace, K. M. & Drakeley, C. J., 2023, In: Scientific Reports. 13, 12998.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Susceptibility to malaria in fulani, Bariba, Otamari and gando individuals living in sympatry in Benin: Role of opsonizing antibodies to Plasmodium falciparum merozoites
Fall, A. K. D. J., Kana, Ikhlaq Hussain, Garcia-Senosiain, A., Henry, B., Dechavanne, C., Garcia, A., Buffet, P., Sabbagh, A., Migot-Nabias, F., Theisen, Michael & Courtin, D., 2023, In: Heliyon. 9, 1, e13092.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
40 Years of Pfs48/45 Research as a Transmission-Blocking Vaccine Target of Plasmodium falciparum Malaria
Sauerwein, R. W., Plieskatt, J. & Theisen, Michael, 2022, In: American Journal of Tropical Medicine and Hygiene. 107, p. 22-26 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-gametocyte antigen humoral immunity and gametocytemia during treatment of uncomplicated falciparum malaria: A multi-national study
O'Flaherty, K., Chan, J-A., Cutts, J. C., Zaloumis, S. G., Ashley, E. A., Phyo, A. P., Drew, D. R., Dondorp, A. M., Day, N. P., Dhorda, M., Fairhurst, R. M., Lim, P., Amaratunga, C., Pukrittayakamee, S., Hien, T. T., Htut, Y., Mayxay, M., Faiz, M. A., Mokuolu, O. A., Onyamboko, M. A. & 9 others, , 2022, In: Frontiers in Cellular and Infection Microbiology. 12, p. 804470Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of Immunoglobulin G3 Hinge Region Length Polymorphism With Cerebral Malaria in Ghanaian Children
Kyei-Baafour, E., Kusi, K. A., Arthur, F. K. N., Sarkodie-Addo, T., Theisen, Michael, Dodoo, D. & Adu, B., 2022, In: The Journal of Infectious Diseases. 225, 10, p. 1786-1790 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellular and antibody response in GMZ2-vaccinated Gabonese volunteers in a controlled human malaria infection trial
Nouatin, O., Ibáñez, J., Fendel, R., Ngoa, U. A., Lorenz, F., Dejon-Agobé, J., Edoa, J. R., Flügge, J., Brückner, S., Esen, M., Theisen, Michael, Hoffman, S. L., Moutairou, K., Luty, A. J. F., Lell, B., Kremsner, P. G., Adegnika, A. A. & Mordmüller, B., 2022, In: Malaria Journal. 21, 1, p. 191Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fcγ receptor IIIB NA1/NA2/SH polymorphisms are associated with malaria susceptibility and antibody levels to P. falciparum merozoite antigens in Beninese children
Fall, A. K. D. J., Courtin, D., Adamou, R., Edslev, S., Hansen, A., Domingo, N., Christiansen, M., Adu, B., Milet, J., Garcia, A., Theisen, Michael, Migot-Nabias, F. & Dechavanne, C., 2022, In: International Journal of Molecular Sciences. 23, 23, 14882.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GMZ2 vaccine-induced antibody responses, naturally acquired immunity and the incidence of malaria in Burkinabe children
Dassah, S., Adu, B., Tiendrebeogo, R. W., Singh, S. K., Arthur, F. K. N., Sirima, S. B. & Theisen, Michael, 2022, In: Frontiers in Immunology. 13, 899223.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heterologous expression and evaluation of novel Plasmodium falciparum transmission blocking vaccine candidates
de Jong, R. M., Singh, S. K., Teelen, K., van de Vegte-Bolmer, M., van Gemert, G., Stone, W. J. R., Locke, E., Plieskatt, J., Theisen, Michael, Bousema, T. & Jore, M. M., 2022, In: Frontiers in Immunology. 13, 909060.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Humoral antimalaria immune response in Nigerian children exposed to helminth and malaria parasites
Adukpo, S., Adedoja, A., Esen, M., Theisen, Michael, Ntoumi, F. & Ojurongbe, O., 2022, In: Frontiers in Immunology. 13, 979727.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Method for production of Cysteine-rich proteins in Lactococcus lactis expression system
Singh, S. K. & Singh, V., 2022, Insoluble Proteins: Methods and Protocols. Springer Science+Business Media, Vol. 2406. p. 189-203 15 p. (Methods in Molecular Biology, Vol. 2406).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Naturally acquired antibodies from Beninese infants promote Plasmodium falciparum merozoite-phagocytosis by human blood leukocytes: implications for control of asymptomatic malaria infections
Fall, A. K. D. J., Kana, Ikhlaq Hussain, Dechavanne, C., Garcia-Senosiain, A., Guitard, E., Milet, J., Massougbodji, A., Garcia, A., Dugoujon, J., Migot-Nabias, F., Theisen, Michael & Courtin, D., 2022, In: Malaria Journal. 21, p. 356Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Naturally acquired antibody response to a Plasmodium falciparum chimeric vaccine candidate GMZ2.6c and its components (MSP-3, GLURP, and Pfs48/45) in individuals living in Brazilian malaria-endemic areas
Baptista, B. O., de Souza, A. B. L., Riccio, E. K. P., Bianco-Junior, C., Totino, P. R. R., Martins da Silva, J. H., Theisen, Michael, Singh, S. K., Amoah, L. E., Ribeiro-Alves, M., Souza, R. M., Lima-Junior, J. C., Daniel-Ribeiro, C. T. & Pratt-Riccio, L. R., 2022, In: Malaria Journal. 21, p. 6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Placental malaria is associated with higher LILRB2 expression in monocyte subsets and lower anti-malarial IgG antibodies during infancy
Dechavanne, C., Nouatin, O., Adamou, R., Edslev, S., Hansen, A., Meurisse, F., Sadissou, I., Gbaguidi, E., Milet, J., Cottrell, G., Gineau, L., Sabbagh, A., Massougbodji, A., Moutairou, K., Donadi, E. A., Carosella, E. D., Moreau, P., Remarque, E., Theisen, M., Rouas-Freiss, N. & 3 others, , 2022, In: Frontiers in Immunology. 13, p. 909831Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Effect of hookworm infection and anthelmintic treatment on naturally acquired antibody responses against the GMZ2 malaria vaccine candidate and constituent antigens
Amoani, B., Gyan, B., Sakyi, S. A., Abu, E. K., Nuvor, S. V., Barnes, P., Sarkodie-Addo, T., Ahenkorah, B., Sewor, C., Dwomoh, D., Theisen, Michael, Cappello, M., Wilson, M. D. & Adu, B., 8 Apr 2021, In: BMC Infectious Diseases. 21, 1, 332.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A reproducible and scalable process for manufacturing a Pfs48/45 based Plasmodium falciparum transmission-blocking vaccine
Singh, S. K., Plieskatt, J., Chourasia, B. K., Fabra-García, A., Garcia-Senosiain, A., Singh, V., Bengtsson, K. L., Reimer, J. M., Sauerwein, R., Jore, M. M. & Theisen, Michael, 2021, In: Frontiers in Immunology. 11, 606266.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity
Fougeroux, C., Goksøyr, L., Idorn, M., Soroka, V., Myeni, S. K., Dagil, R., Janitzek, C. M., Søgaard, M., Aves, K-L., Horsted, E. W., Erdogan, S. M., Gustavsson, T., Dorosz, J., Clemmensen, S., Fredsgaard, L., Thrane, S., Vidal-Calvo, E. E., Khalifé, P., Hulen, T. M., Choudhary, S. & 27 others, , 2021, In: Nature Communications. 12, 1, p. 324Research output: Contribution to journal › Journal article › Research › peer-review
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Natural antibody responses to Plasmodium falciparum MSP3 and GLURP(R0) antigens are associated with low parasite densities in malaria patients living in the Central Region of Ghana
Research output: Contribution to journal › Journal article › Research › peer-review
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228
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Construct design, production, and characterization of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine
Research output: Contribution to journal › Journal article › Research › peer-review
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206
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Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Latest publications
Clinical formulation development of Plasmodium falciparum malaria vaccine candidates based on Pfs48/45, Pfs230, and PfCSP
Research output: Contribution to journal › Journal article › Research › peer-review
A Pfs48/45-based vaccine to block Plasmodium falciparum transmission: phase 1, open-label, clinical trial
Research output: Contribution to journal › Journal article › Research › peer-review
A randomized first-in-human phase I trial of differentially adjuvanted Pfs48/45 malaria vaccines in Burkinabé adults
Research output: Contribution to journal › Journal article › Research › peer-review