GLURP team

  1. 2018
  2. Published

    Plasmodium falciparum MSP3 exists in a complex on the merozoite surface and generates antibody response during natural infection

    Deshmukh, A., Chourasia, B. K., Mehrotra, S., Kana, Ikhlaq Hussain, Paul, G., Panda, A., Kaur, I., Singh, S. K., Rathore, S., Das, A., Gupta, P., Kalamuddin, M., Gakhar, S. K., Mohmmed, A., Theisen, Michael & Malhotra, P., Aug 2018, In: Infection and Immunity. 86, 8, e00067-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity

    Stone, W. J. R., Campo, J. J., Ouédraogo, A. L., Meerstein-Kessel, L., Morlais, I., Da, D., Cohuet, A., Nsango, S., Sutherland, C. J., van de Vegte-Bolmer, M., Siebelink-Stoter, R., van Gemert, G-J., Graumans, W., Lanke, K., Shandling, A. D., Pablo, J. V., Teng, A. A., Jones, S., de Jong, R. M., Fabra-García, A. & 14 others, Bradley, J., Roeffen, W., Lasonder, E., Gremo, G., Schwarzer, E., Janse, C. J., Singh, S. K., Theisen, Michael, Felgner, P., Marti, M., Drakeley, C., Sauerwein, R., Bousema, T. & Jore, M. M., 8 Feb 2018, In: Nature Communications. 9, 1, 14 p., 558.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Assessment of the quality and quantity of naturally induced antibody responses to EBA175RIII-V in Ghanaian children living in two communities with varying malaria transmission patterns

    Abagna, H. B., Acquah, F. K., Okonu, R., Aryee, N. A., Theisen, Michael & Amoah, L. E., 8 Jan 2018, In: Malaria Journal. 17, 1, 11 p., 14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Dynamics of anti-MSP3 and Pfs230 antibody responses and multiplicity of infection in asymptomatic children from southern Ghana

    Amoah, L. E., Acquah, F. K., Ayanful-Torgby, R., Oppong, A., Abankwa, J., Obboh, E. K., Singh, S. K. & Theisen, Michael, 5 Jan 2018, In: Parasites & Vectors. 11, 1, 9 p., 13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Lactococcus lactis provides an efficient platform for production of disulfide-rich recombinant proteins from Plasmodium falciparum

    Singh, S. K., Tiendrebeogo, R. W., Chourasia, B. K., Kana, Ikhlaq Hussain, Singh, S. & Theisen, Michael, 2018, In: Microbial Cell Factories. 17, 13 p., 55.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Characterization of Plasmodium falciparum and Plasmodium vivax recent exposure in an area of significantly decreased transmission intensity in Central Vietnam

    Kattenberg, J. H., Erhart, A., Truong, M. H., Rovira-Vallbona, E., Vu, K. A. D., Nguyen, T. H. N., Nguyen, V. H., Nguyen, V. V., Bannister-Tyrrell, M., Theisen, Michael, Bennet, A., Lover, A. A., Tran, T. D., Nguyen, X. X. & Rosanas-Urgell, A., 2018, In: Malaria Journal. 17, 17 p., 180.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Cytophilic Antibodies Against Key Plasmodium falciparum Blood Stage Antigens Contribute to Protection Against Clinical Malaria in a High Transmission Region of Eastern India

    Kana, Ikhlaq Hussain, Garcia Senosiain, A., Singh, S., Tiendrebeogo, R. W., Chourasia, B., Malhotra, P., Sharma, S. K., Das, M. K., Singh, S., Adu, B. & Theisen, Michael, 2018, In: The Journal of Infectious Diseases. 218, 6, p. 956-965

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Molecular and functional characterization of Fcγ receptor IIIb-ligand interaction: Implications for neutrophil-mediated immune mechanisms in malaria

    Simtong, P., Romphruk, A. V., Traum, A., Burg-Roderfeld, M., Bein, G., Jakubowski, K., Dominik, A., Theisen, Michael, Kana, Ikhlaq Hussain, Sachs, U. J. & Santoso, S., 2018, In: Infection and Immunity. 86, 8, e00924-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Protein-protein interaction studies reveal the Plasmodium falciparum merozoite surface protein-1 region involved in a complex formation that binds to human erythrocytes

    Paul, G., Deshmukh, A., Kumar Chourasia, B., Kalamuddin, M., Panda, A., Kumar Singh, S., Gupta, P. K., Mohmmed, A., Chauhan, V. S., Theisen, Michael & Malhotra, P., 2018, In: Biochemical Journal. 475, 6, p. 1197-1209 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    SURGE complex of Plasmodium falciparum in the rhoptry-neck (SURFIN4.2-RON4-GLURP) contributes to merozoite invasion

    Quintana Varon, Maria del Pilar, Ch'ng, J., Zandian, A., Imam, M., Hultenby, K., Theisen, Michael, Nilsson, P., Qundos, U., Moll, K., Chan, S. & Wahlgren, M., 2018, In: PLOS ONE. 13, 8, 25 p., e0201669.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2017
  13. Published

    ANTIBODY DEPENDENT CELLULAR INHIBITION IS ASSOCIATED WITH PROTECTION AGAINST FEBRILE MALARIA IN A LONGITUDINAL COHORT STUDY INVOLVING GHANAIAN CHILDREN

    Tiendrebeogo, R. W., Nov 2017, In: American Journal of Tropical Medicine and Hygiene. 95, 5, p. 112-112

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  14. Published

    Expression, Purification and Characterization of GMZ2'.10C, a Complex Disulphide-Bonded Fusion Protein Vaccine Candidate against the Asexual and Sexual Life-Stages of the Malaria-Causing Plasmodium falciparum Parasite

    Mistarz, U. H., Singh, S. K., Nguyen, T. T. T. N., Roeffen, W., Yang, F., Lissau, C., Madsen, S. M., Vrang, A., Tiendrebeogo, R. W., Kana, Ikhlaq Hussain, Sauerwein, R. W., Theisen, Michael & Rand, Kasper Dyrberg, 1 Sep 2017, In: Pharmaceutical Research. 34, 9, p. 1970-1983 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Malaria epidemiology in an area of stable transmission in tribal population of Jharkhand, India

    Das, M. K., Prajapati, B. K., Tiendrebeogo, R. W., Ranjan, K., Adu, B., Srivastava, A., Khera, H. K., Chauhan, N., Tevatiya, S., Kana, Ikhlaq Hussain, Sharma, S. K., Singh, S. & Theisen, Michael, 2 May 2017, In: Malaria Journal. 16, 10 p., 181.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    A novel Pfs38 protein complex on the surface of Plasmodium falciparum blood-stage merozoites

    Paul, G., Deshmukh, A., Kaur, I., Rathore, S., Dabral, S., Panda, A., Singh, S. K., Mohmmed, A., Theisen, Michael & Malhotra, P., 16 Feb 2017, In: Malaria Journal. 16, 1, 15 p., 79.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Naturally acquired antibodies target the glutamate-rich protein on intact merozoites and predict protection against febrile malaria

    Kana, Ikhlaq Hussain, Adu, B., Tiendrebeogo, R. W., Singh, S. K., Dodoo, D. & Theisen, Michael, 15 Feb 2017, In: The Journal of Infectious Diseases. 215, 4, p. 623-630 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Efficacy of the GMZ2 malaria vaccine in African children

    Milligan, P., Flach, C. & Theisen, Michael, 5 Jan 2017, In: Vaccine. 35, 2, p. 202 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  19. Published

    A HR-MS based method for the determination of chorismate synthase activity

    Khera, H. K., Singh, S. K., Mir, R., Bharadwaj, V. & Singh, S., 2017, In: Protein and Peptide Letters. 24, 3, p. 229-234 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Antibody responses to two new Lactococcus lactis-produced recombinant Pfs48/45 and Pfs230 proteins increase with age in malaria patients living in the Central Region of Ghana

    Acquah, F. K., Obboh, E. K., Asare, K., Boampong, J. N., Nuvor, S. V., Singh, S. K., Theisen, Michael, Williamson, K. C. & Amoah, L. E., 2017, In: Malaria Journal. 16, 11 p., 306.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    BIOMARKER DEVELOPMENT AND PRIORITIZATION OF GLOBALLY SUITABLE PLASMODIUM FALCIPARUM MEROZOITE-STAGE VACCINE CANDIDATE ANTIGENS

    Kana, Ikhlaq Hussain, 2017, In: American Journal of Tropical Medicine and Hygiene. 97, 5 Supplement, p. 106-106 342.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  22. Published

    Construct design, production, and characterization of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine

    Singh, S. K., Roeffen, W., Mistarz, U. H., Chourasia, B. K., Yang, F., Rand, Kasper Dyrberg, Sauerwein, R. W. & Theisen, Michael, 2017, In: Microbial Cell Factories. 16, 1, 11 p., 97.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Improving the malaria transmission-blocking activity of a Plasmodium falciparum 48/45 based vaccine antigen by SpyTag/SpyCatcher mediated virus-like display

    Singh, S. K., Thrane, Susan, Janitzek, C. M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Theisen, Michael, Salanti, Ali & Sander, Adam F. , 2017, In: Vaccine. 35, 30, p. 3726-3732 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Natural antibody responses to Plasmodium falciparum MSP3 and GLURP(R0) antigens are associated with low parasite densities in malaria patients living in the Central Region of Ghana

    Amoah, L. E., Nuvor, S. V., Obboh, E. K., Acquah, F. K., Asare, K., Singh, S. K., Boampong, J. N., Theisen, Michael & Williamson, K. C., 2017, In: Parasites and Vectors. 10, 1, 9 p., 395.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Recognition of Plasmodium falciparum mature gametocyte-infected erythrocytes by antibodies of semi-immune adults and malaria-exposed children from Gabon

    Gebru, T., Ajua, A., Theisen, Michael, Esen, M., Ngoa, U. A., Issifou, S., Adegnika, A. A., Kremsner, P. G., Mordmüller, B. & Held, J., 2017, In: Malaria Journal. 16, 11 p., 176.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    The GMZ2 malaria vaccine: from concept to efficacy in humans

    Theisen, Michael, Adu, B., Mordmueller, B. & Singh, S., 2017, In: Expert Review of Vaccines. 16, 9, p. 907-917

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Towards clinical development of a Pfs48/45-based transmission blocking malaria vaccine

    Theisen, Michael, Jore, M. M. & Sauerwein, R., 2017, In: Expert Review of Vaccines. 16, 4, p. 329-336 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review