- 2018
- Published
Plasmodium falciparum MSP3 exists in a complex on the merozoite surface and generates antibody response during natural infection
Deshmukh, A., Chourasia, B. K., Mehrotra, S., Kana, Ikhlaq Hussain, Paul, G., Panda, A., Kaur, I., Singh, S. K., Rathore, S., Das, A., Gupta, P., Kalamuddin, M., Gakhar, S. K., Mohmmed, A., Theisen, Michael & Malhotra, P., Aug 2018, In: Infection and Immunity. 86, 8, e00067-18.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity
Stone, W. J. R., Campo, J. J., Ouédraogo, A. L., Meerstein-Kessel, L., Morlais, I., Da, D., Cohuet, A., Nsango, S., Sutherland, C. J., van de Vegte-Bolmer, M., Siebelink-Stoter, R., van Gemert, G-J., Graumans, W., Lanke, K., Shandling, A. D., Pablo, J. V., Teng, A. A., Jones, S., de Jong, R. M., Fabra-García, A. & 14 others, , 8 Feb 2018, In: Nature Communications. 9, 1, 14 p., 558.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessment of the quality and quantity of naturally induced antibody responses to EBA175RIII-V in Ghanaian children living in two communities with varying malaria transmission patterns
Abagna, H. B., Acquah, F. K., Okonu, R., Aryee, N. A., Theisen, Michael & Amoah, L. E., 8 Jan 2018, In: Malaria Journal. 17, 1, 11 p., 14.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamics of anti-MSP3 and Pfs230 antibody responses and multiplicity of infection in asymptomatic children from southern Ghana
Amoah, L. E., Acquah, F. K., Ayanful-Torgby, R., Oppong, A., Abankwa, J., Obboh, E. K., Singh, S. K. & Theisen, Michael, 5 Jan 2018, In: Parasites & Vectors. 11, 1, 9 p., 13.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lactococcus lactis provides an efficient platform for production of disulfide-rich recombinant proteins from Plasmodium falciparum
Singh, S. K., Tiendrebeogo, R. W., Chourasia, B. K., Kana, Ikhlaq Hussain, Singh, S. & Theisen, Michael, 2018, In: Microbial Cell Factories. 17, 13 p., 55.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of Plasmodium falciparum and Plasmodium vivax recent exposure in an area of significantly decreased transmission intensity in Central Vietnam
Kattenberg, J. H., Erhart, A., Truong, M. H., Rovira-Vallbona, E., Vu, K. A. D., Nguyen, T. H. N., Nguyen, V. H., Nguyen, V. V., Bannister-Tyrrell, M., Theisen, Michael, Bennet, A., Lover, A. A., Tran, T. D., Nguyen, X. X. & Rosanas-Urgell, A., 2018, In: Malaria Journal. 17, 17 p., 180.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cytophilic Antibodies Against Key Plasmodium falciparum Blood Stage Antigens Contribute to Protection Against Clinical Malaria in a High Transmission Region of Eastern India
Kana, Ikhlaq Hussain, Garcia Senosiain, A., Singh, S., Tiendrebeogo, R. W., Chourasia, B., Malhotra, P., Sharma, S. K., Das, M. K., Singh, S., Adu, B. & Theisen, Michael, 2018, In: The Journal of Infectious Diseases. 218, 6, p. 956-965Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular and functional characterization of Fcγ receptor IIIb-ligand interaction: Implications for neutrophil-mediated immune mechanisms in malaria
Simtong, P., Romphruk, A. V., Traum, A., Burg-Roderfeld, M., Bein, G., Jakubowski, K., Dominik, A., Theisen, Michael, Kana, Ikhlaq Hussain, Sachs, U. J. & Santoso, S., 2018, In: Infection and Immunity. 86, 8, e00924-17.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein-protein interaction studies reveal the Plasmodium falciparum merozoite surface protein-1 region involved in a complex formation that binds to human erythrocytes
Paul, G., Deshmukh, A., Kumar Chourasia, B., Kalamuddin, M., Panda, A., Kumar Singh, S., Gupta, P. K., Mohmmed, A., Chauhan, V. S., Theisen, Michael & Malhotra, P., 2018, In: Biochemical Journal. 475, 6, p. 1197-1209 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SURGE complex of Plasmodium falciparum in the rhoptry-neck (SURFIN4.2-RON4-GLURP) contributes to merozoite invasion
Quintana Varon, Maria del Pilar, Ch'ng, J., Zandian, A., Imam, M., Hultenby, K., Theisen, Michael, Nilsson, P., Qundos, U., Moll, K., Chan, S. & Wahlgren, M., 2018, In: PLOS ONE. 13, 8, 25 p., e0201669.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
ANTIBODY DEPENDENT CELLULAR INHIBITION IS ASSOCIATED WITH PROTECTION AGAINST FEBRILE MALARIA IN A LONGITUDINAL COHORT STUDY INVOLVING GHANAIAN CHILDREN
Tiendrebeogo, R. W., Nov 2017, In: American Journal of Tropical Medicine and Hygiene. 95, 5, p. 112-112Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Expression, Purification and Characterization of GMZ2'.10C, a Complex Disulphide-Bonded Fusion Protein Vaccine Candidate against the Asexual and Sexual Life-Stages of the Malaria-Causing Plasmodium falciparum Parasite
Mistarz, U. H., Singh, S. K., Nguyen, T. T. T. N., Roeffen, W., Yang, F., Lissau, C., Madsen, S. M., Vrang, A., Tiendrebeogo, R. W., Kana, Ikhlaq Hussain, Sauerwein, R. W., Theisen, Michael & Rand, Kasper Dyrberg, 1 Sep 2017, In: Pharmaceutical Research. 34, 9, p. 1970-1983 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Malaria epidemiology in an area of stable transmission in tribal population of Jharkhand, India
Das, M. K., Prajapati, B. K., Tiendrebeogo, R. W., Ranjan, K., Adu, B., Srivastava, A., Khera, H. K., Chauhan, N., Tevatiya, S., Kana, Ikhlaq Hussain, Sharma, S. K., Singh, S. & Theisen, Michael, 2 May 2017, In: Malaria Journal. 16, 10 p., 181.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel Pfs38 protein complex on the surface of Plasmodium falciparum blood-stage merozoites
Paul, G., Deshmukh, A., Kaur, I., Rathore, S., Dabral, S., Panda, A., Singh, S. K., Mohmmed, A., Theisen, Michael & Malhotra, P., 16 Feb 2017, In: Malaria Journal. 16, 1, 15 p., 79.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Naturally acquired antibodies target the glutamate-rich protein on intact merozoites and predict protection against febrile malaria
Kana, Ikhlaq Hussain, Adu, B., Tiendrebeogo, R. W., Singh, S. K., Dodoo, D. & Theisen, Michael, 15 Feb 2017, In: The Journal of Infectious Diseases. 215, 4, p. 623-630 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficacy of the GMZ2 malaria vaccine in African children
Milligan, P., Flach, C. & Theisen, Michael, 5 Jan 2017, In: Vaccine. 35, 2, p. 202 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
A HR-MS based method for the determination of chorismate synthase activity
Khera, H. K., Singh, S. K., Mir, R., Bharadwaj, V. & Singh, S., 2017, In: Protein and Peptide Letters. 24, 3, p. 229-234 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibody responses to two new Lactococcus lactis-produced recombinant Pfs48/45 and Pfs230 proteins increase with age in malaria patients living in the Central Region of Ghana
Acquah, F. K., Obboh, E. K., Asare, K., Boampong, J. N., Nuvor, S. V., Singh, S. K., Theisen, Michael, Williamson, K. C. & Amoah, L. E., 2017, In: Malaria Journal. 16, 11 p., 306.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
BIOMARKER DEVELOPMENT AND PRIORITIZATION OF GLOBALLY SUITABLE PLASMODIUM FALCIPARUM MEROZOITE-STAGE VACCINE CANDIDATE ANTIGENS
Kana, Ikhlaq Hussain, 2017, In: American Journal of Tropical Medicine and Hygiene. 97, 5 Supplement, p. 106-106 342.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Construct design, production, and characterization of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine
Singh, S. K., Roeffen, W., Mistarz, U. H., Chourasia, B. K., Yang, F., Rand, Kasper Dyrberg, Sauerwein, R. W. & Theisen, Michael, 2017, In: Microbial Cell Factories. 16, 1, 11 p., 97.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improving the malaria transmission-blocking activity of a Plasmodium falciparum 48/45 based vaccine antigen by SpyTag/SpyCatcher mediated virus-like display
Singh, S. K., Thrane, Susan, Janitzek, C. M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Theisen, Michael, Salanti, Ali & Sander, Adam F. , 2017, In: Vaccine. 35, 30, p. 3726-3732 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Natural antibody responses to Plasmodium falciparum MSP3 and GLURP(R0) antigens are associated with low parasite densities in malaria patients living in the Central Region of Ghana
Amoah, L. E., Nuvor, S. V., Obboh, E. K., Acquah, F. K., Asare, K., Singh, S. K., Boampong, J. N., Theisen, Michael & Williamson, K. C., 2017, In: Parasites and Vectors. 10, 1, 9 p., 395.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recognition of Plasmodium falciparum mature gametocyte-infected erythrocytes by antibodies of semi-immune adults and malaria-exposed children from Gabon
Gebru, T., Ajua, A., Theisen, Michael, Esen, M., Ngoa, U. A., Issifou, S., Adegnika, A. A., Kremsner, P. G., Mordmüller, B. & Held, J., 2017, In: Malaria Journal. 16, 11 p., 176.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The GMZ2 malaria vaccine: from concept to efficacy in humans
Theisen, Michael, Adu, B., Mordmueller, B. & Singh, S., 2017, In: Expert Review of Vaccines. 16, 9, p. 907-917Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Towards clinical development of a Pfs48/45-based transmission blocking malaria vaccine
Theisen, Michael, Jore, M. M. & Sauerwein, R., 2017, In: Expert Review of Vaccines. 16, 4, p. 329-336 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural antibody responses to Plasmodium falciparum MSP3 and GLURP(R0) antigens are associated with low parasite densities in malaria patients living in the Central Region of Ghana
Research output: Contribution to journal › Journal article › Research › peer-review
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Construct design, production, and characterization of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine
Research output: Contribution to journal › Journal article › Research › peer-review
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Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity
Research output: Contribution to journal › Journal article › Research › peer-review
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Latest publications
Clinical formulation development of Plasmodium falciparum malaria vaccine candidates based on Pfs48/45, Pfs230, and PfCSP
Research output: Contribution to journal › Journal article › Research › peer-review
A Pfs48/45-based vaccine to block Plasmodium falciparum transmission: phase 1, open-label, clinical trial
Research output: Contribution to journal › Journal article › Research › peer-review
A randomized first-in-human phase I trial of differentially adjuvanted Pfs48/45 malaria vaccines in Burkinabé adults
Research output: Contribution to journal › Journal article › Research › peer-review