GLURP team

  1. Published

    40 Years of Pfs48/45 Research as a Transmission-Blocking Vaccine Target of Plasmodium falciparum Malaria

    Sauerwein, R. W., Plieskatt, J. & Theisen, Michael, 2022, In: American Journal of Tropical Medicine and Hygiene. 107, p. 22-26 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Lactococcus lactis provides an efficient platform for production of disulfide-rich recombinant proteins from Plasmodium falciparum

    Singh, S. K., Tiendrebeogo, R. W., Chourasia, B. K., Kana, Ikhlaq Hussain, Singh, S. & Theisen, Michael, 2018, In: Microbial Cell Factories. 17, 13 p., 55.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Plasmodium falciparum Clag9-associated PfRhopH complex is involved in merozoite binding to human erythrocytes

    Chourasia, B. K., Deshmukh, A., Kaur, I., Paul, G., Panda, A., Rathore, S., Singh, S. K., Theisen, Michael, Mohmmed, A. & Malhotra, P., 2020, In: Infection and Immunity. 88, 2, e00504-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Plasmodium falciparum MSP3 exists in a complex on the merozoite surface and generates antibody response during natural infection

    Deshmukh, A., Chourasia, B. K., Mehrotra, S., Kana, Ikhlaq Hussain, Paul, G., Panda, A., Kaur, I., Singh, S. K., Rathore, S., Das, A., Gupta, P., Kalamuddin, M., Gakhar, S. K., Mohmmed, A., Theisen, Michael & Malhotra, P., Aug 2018, In: Infection and Immunity. 86, 8, e00067-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Plasmodium falciparum merozoite surface antigen-specific cytophilic IgG and control of malaria infection in a Beninese birth cohort

    Adamou, R., Dechavanne, C., Sadissou, I., d'Almeida, T., Bouraima, A., Sonon, P., Amoussa, R., Cottrell, G., Le Port, A., Theisen, M., Remarque, E. J., Longacre, S., Moutairou, K., Massougbodji, A., Luty, A. J. F., Nuel, G., Migot-Nabias, F., Sanni, A., Garcia, A., Milet, J. & 1 others, Courtin, D., 2019, In: Malaria Journal. 18, 11 p., 194.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A Plasmodium falciparum 48/45 single epitope R0.6C subunit protein elicits high levels of transmission blocking antibodies

    Singh, S. K., Roeffen, W., Andersen, G., Bousema, T., Christiansen, M., Sauerwein, R. & Theisen, Michael, 15 Apr 2015, In: Vaccine. 33, 16, p. 1981-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A HR-MS based method for the determination of chorismate synthase activity

    Khera, H. K., Singh, S. K., Mir, R., Bharadwaj, V. & Singh, S., 2017, In: Protein and Peptide Letters. 24, 3, p. 229-234 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    A Pfs48/45-based vaccine to block Plasmodium falciparum transmission: phase 1, open-label, clinical trial

    Alkema, M., Smit, M. J., Marin-Mogollon, C., Totté, K., Teelen, K., van Gemert, G. J., van de Vegte-Bolmer, M., Mordmüller, B. G., Reimer, J. M., Lövgren-Bengtsson, K. L., Sauerwein, R. W., Bousema, T., Plieskatt, J., Theisen, Michael, Jore, M. M. & McCall, M. B. B., 2024, In: BMC Medicine. 22, 1, 12 p., 170.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    A flow cytometry-based workflow for detection and quantification of anti-plasmodial antibodies in vaccinated and naturally exposed individuals

    Ajua, A., Engleitner, T., Esen, M., Theisen, Michael, Issifou, S. & Mordmüller, B., 2012, In: Malaria Journal. 11, 1, p. 367

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A multi-stage malaria vaccine candidate targeting both transmission and asexual parasite life-cycle stages

    Theisen, Michael, Roeffen, W., Singh, S. K., Andersen, G., Amoah, L., van de Vegte-Bolmer, M., Arens, T., Tiendrebeogo, R. W., Jones, S., Bousema, T., Adu, B., Dziegiel, Morten Hanefeld, Christiansen, M. & Sauerwein, R., 2014, In: Vaccine. 32, 22, p. 2623–2630 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A novel Pfs38 protein complex on the surface of Plasmodium falciparum blood-stage merozoites

    Paul, G., Deshmukh, A., Kaur, I., Rathore, S., Dabral, S., Panda, A., Singh, S. K., Mohmmed, A., Theisen, Michael & Malhotra, P., 16 Feb 2017, In: Malaria Journal. 16, 1, 15 p., 79.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    A phase 2b randomized, controlled trial of the efficacy of the GMZ2 malaria vaccine in African children

    Sirima, S. B., Mordmüller, B., Milligan, P., Ngoa, U. A., Kironde, F., Atuguba, F., Tiono, A. B., Issifou, S., Kaddumukasa, M., Bangre, O., Flach, C., Christiansen, M., Bang, P., Chilengi, R., Jepsen, S., Kremsner, P. G. & Theisen, Michael, Aug 2016, In: Vaccine. 34, 38, p. 4536-4542 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A randomized controlled Phase Ib trial of the malaria vaccine candidate GMZ2 in African children

    Bélard, S., Issifou, S., Hounkpatin, A. B., Schaumburg, F., Ngoa, U. A., Esen, M., Fendel, R., de Salazar, P. M., Mürbeth, R. E., Milligan, P., Imbault, N., Imoukhuede, E. B., Theisen, Michael, Jepsen, S., Noor, R. A., Okech, B., Kremsner, P. G. & Mordmüller, B., 2011, In: P L o S One. 6, 7, p. e22525

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    A randomized first-in-human phase I trial of differentially adjuvanted Pfs48/45 malaria vaccines in Burkinabé adults

    Tiono, A. B., Plieskatt, J. L., Ouedraogo, A., Soulama, B. I., Miura, K., Bougouma, E. C., Naghizadeh, M., Barry, A., Yaro, J. B. B., Ezinmegnon, S., Henry, N., Ofori, E. A., Adu, B., Singh, S. K., Konkobo, A., Lövgren Bengtsson, K., Diarra, A., Carnrot, C., Reimer, J. M., Ouedraogo, A. & 6 others, Tienta, M., Long, C. A., Ouedraogo, I. N., Sagara, I., Sirima, S. B. & Theisen, Michael, 2024, In: The Journal of Clinical Investigation. 134, 7, 15 p., e175707.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    A reproducible and scalable process for manufacturing a Pfs48/45 based Plasmodium falciparum transmission-blocking vaccine

    Singh, S. K., Plieskatt, J., Chourasia, B. K., Fabra-García, A., Garcia-Senosiain, A., Singh, V., Bengtsson, K. L., Reimer, J. M., Sauerwein, R., Jore, M. M. & Theisen, Michael, 2021, In: Frontiers in Immunology. 11, 606266.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    A synthetic TLR4 agonist formulated in an emulsion enhances humoral and Type 1 cellular immune responses against GMZ2 - A GLURP-MSP3 fusion protein malaria vaccine candidate

    Lousada-Dietrich, S., Jogdand, P. S., Jepsen, S., Valadão Vaz dos Santos Pinto, V. M., Ditlev, S. B., Christiansen, M., Larsen, S. O., Fox, C. B., Raman, V. S., Howard, R. F., Vedvick, T. S., Ireton, G., Carter, D., Reed, S. G. & Theisen, Michael, 12 Apr 2011, In: Vaccine. 29, 17, p. 3284-92 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    A threshold concentration of anti-merozoite antibodies is required for protection from clinical episodes of malaria

    Murungi, L. M., Kamuyu, G., Lowe, B., Bejon, P., Theisen, Michael, Kinyanjui, S. M., Marsh, K. & Osier, F. H. A., 20 Aug 2013, In: Vaccine. 31, 37, p. 3936-42 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    ANTIBODY DEPENDENT CELLULAR INHIBITION IS ASSOCIATED WITH PROTECTION AGAINST FEBRILE MALARIA IN A LONGITUDINAL COHORT STUDY INVOLVING GHANAIAN CHILDREN

    Tiendrebeogo, R. W., Nov 2017, In: American Journal of Tropical Medicine and Hygiene. 95, 5, p. 112-112

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  19. Published

    Acquisition of natural humoral immunity to P. falciparum in early life in Benin: impact of clinical, environmental and host factors

    Dechavanne, C., Sadissou, I., Bouraima, A., Ahouangninou, C., Amoussa, R., Milet, J., Moutairou, K., Massougbodji, A., Theisen, Michael, Remarque, E. J., Courtin, D., Nuel, G., Migot-Nabias, F. & Garcia, A., 2016, In: Scientific Reports. 6, 9 p., 33961.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Analysis of the OspE determinants involved in binding of factor H and OspE-targeting antibodies elicited during Borrelia burgdorferi infection in mice

    Metts, M. S., McDowell, J. V., Theisen, Michael, Hansen, Paul Robert & Marconi, R. T., 1 Jun 2003, In: Infection and Immunity. 71, 6, p. 3587-3596 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Anti-gametocyte antigen humoral immunity and gametocytemia during treatment of uncomplicated falciparum malaria: A multi-national study

    O'Flaherty, K., Chan, J-A., Cutts, J. C., Zaloumis, S. G., Ashley, E. A., Phyo, A. P., Drew, D. R., Dondorp, A. M., Day, N. P., Dhorda, M., Fairhurst, R. M., Lim, P., Amaratunga, C., Pukrittayakamee, S., Hien, T. T., Htut, Y., Mayxay, M., Faiz, M. A., Mokuolu, O. A., Onyamboko, M. A. & 9 others, Fanello, C., Takashima, E., Tsuboi, T., Theisen, Michael, Nosten, F., Beeson, J. G., Simpson, J. A., White, N. J. & Fowkes, F. J. I., 2022, In: Frontiers in Cellular and Infection Microbiology. 12, p. 804470

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Antibodies against the Plasmodium falciparum glutamate-rich protein from naturally exposed individuals living in a Brazilian malaria-endemic area can inhibit in vitro parasite growth

    Pratt-Riccio, L. R., Bianco, C., Totino, P. R. R., Perce-Da-Silva, D. D. S., Silva, L. A., Riccio, E. K. P., Ennes-Vidal, V., Neves-Ferreira, A. G. C., Perales, J., Da Rocha, S. L. G., Dias-Da-Silva, F., Ferreira-da-Cruz, M. D. F., Daniel-Ribeiro, C. T., De Oliveira-Ferreira, J., Theisen, Michael, Carvalho, L. J. D. M. & Banic, D. M., 2011, In: Memórias do Instituto Oswaldo Cruz. 106 Suppl 1, p. 34-43 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Antibodies to malaria vaccine candidates are associated with chloroquine or sulphadoxine/pyrimethamine treatment efficacy in children in an endemic area of Burkina Faso

    Diarra, A., Nebie, I., Tiono, A., Soulama, I., Ouedraogo, A., Konate, A., Theisen, Michael, Dodoo, D., Traore, A. & Sirima, S. B., 2012, In: Malaria Journal. 11, 1, p. 79

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Antibody levels against GLURP R2, MSP1 block 2 hybrid and AS202.11 and the risk of malaria in children living in hyperendemic (Burkina Faso) and hypo-endemic (Ghana) areas

    Adu, B., Cherif, M. K., Bosomprah, S., Diarra, A., Arthur, F. K. N., Dickson, E. K., Corradin, G., Cavanagh, D. R., Theisen, Michael, Sirima, S. B., Nebie, I. & Dodoo, D., 27 Feb 2016, In: Malaria Journal. 15, 1, 123.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Antibody responses to a suite of novel serological markers for malaria surveillance demonstrate strong correlation with clinical and parasitological infection across seasons and transmission settings in The Gambia

    Wu, L., Mwesigwa, J., Affara, M., Bah, M., Correa, S., Hall, T., Singh, S. K., Beeson, J. G., Tetteh, K. K. A., Kleinschmidt, I., D'Alessandro, U. & Drakeley, C., 2020, In: BMC Medicine. 18, 1, 304.

    Research output: Contribution to journalJournal articleResearchpeer-review

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