- 2016
- Published
Breaking down brain barrier breaches in cerebral malaria
Petersen, J. E. V., Lavstsen, Thomas & Craig, A., 3 Oct 2016, In: Journal of Clinical Investigation. 126, 10, p. 3725-3727 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Plasmodium falciparum Plasmodium helical interspersed subtelomeric proteins contribute to cytoadherence and anchor P. falciparum erythrocyte membrane protein 1 to the host cell cytoskeleton
Oberli, A., Zurbrügg, L., Rusch, S., Brand, F., Butler, M. E., Day, J. L., Cutts, E. E., Lavstsen, Thomas, Vakonakis, I. & Beck, H., Oct 2016, In: Cellular Microbiology. 18, 10, p. 1415-1428 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The structural basis for CD36 binding by the malaria parasite
Hsieh, F., Turner, Louise, Bolla, J. R., Robinson, C. V., Lavstsen, Thomas & Higgins, M. K., 27 Sep 2016, In: Nature Communications. 7, 11 p., 12837.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The endothelial protein C receptor rs867186-GG genotype is associated with increased soluble EPCR and could mediate protection against severe malaria
Shabani, E., Opoka, R. O., Bangirana, P., Park, G. S., Vercellotti, G. M., Guan, W., Hodges, J. S., Lavstsen, Thomas & John, C. C., 3 Jun 2016, In: Scientific Reports. 6, 11 p., 27084.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adhesion of Plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue: a novel model of placental malaria
Pehrson, Caroline, Mathiesen, Line, Heno, K. K., Salanti, Ali, dos Santos Marques Resende, M., Dzikowski, R., Damm, Peter, Hansson, S. R., King, C. L., Schneider, H., Wang, Christian William, Lavstsen, Thomas, Theander, Thor Grundtvig, Knudsen, Lisbeth E. & Nielsen, Morten Agertoug, 26 May 2016, In: Malaria Journal. 15, 12 p., 292.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of EPCR in the pathogenesis of severe malaria
Mosnier, L. O. & Lavstsen, Thomas, May 2016, In: Thrombosis Research. 141 , S2, p. S46-S49 4 p.Research output: Contribution to journal › Conference article › Research › peer-review
- Published
Plasmodium falciparum var genes expressed in children with severe malaria encode CIDRα1 domains
Jespersen, Jakob Schmidt, Wang, Christian William, Mkumbaye, S. I., Minja, D. T., Petersen, Bent, Turner, Louise, Petersen, J. E., Lusingu, J. P., Theander, Thor Grundtvig & Lavstsen, Thomas, 2016, In: EMBO Molecular Medicine. 8, 8, p. 839-850 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differences in PfEMP1s recognized by antibodies from patients with uncomplicated or severe malaria
Duffy, M. F., Noviyanti, R., Tsuboi, T., Feng, Z., Trianty, L., Sebayang, B. F., Takashima, E., Sumardy, F., Lampah, D. A., Turner, Louise, Lavstsen, Thomas, Fowkes, F. J. I., Siba, P., Rogerson, S. J., Theander, Thor Grundtvig, Marfurt, J., Price, R. N., Anstey, N. M., Brown, G. V. & Papenfuss, A. T., 2016, In: Malaria Journal. 15, 12 p., 258.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Protein C system defects inflicted by the malaria parasite protein PfEMP1 can be overcome by a soluble EPCR variant
Petersen, J. E. V., Bouwens, E. A. M., Tamayo, I., Turner, Louise, Wang, Christian William, Stins, M., Theander, Thor Grundtvig, Hermida, J., Mosnier, L. O. & Lavstsen, Thomas, Nov 2015, In: Thrombosis and Haemostasis. 114, 5, p. 1038-48 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IgG antibodies to endothelial protein C receptor-binding Cysteine-rich interdomain region domains of Plasmodium falciparum erythrocyte membrane protein 1 are acquired early in life in individuals exposed to malaria
Turner, Louise, Lavstsen, Thomas, Mmbando, B. P., Wang, Christian William, Magistrado, P. A., Vestergaard, L. S., Ishengoma, D. S., Minja, D. T. R., Lusingu, J. P. & Theander, Thor Grundtvig, Aug 2015, In: Infection and Immunity. 83, 8, p. 3096-103 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rifins, rosetting, and red blood cells
Wang, Christian William & Hviid, Lars, Jul 2015, In: Trends in Parasitology. 31, 7, p. 285-6 2 p.Research output: Contribution to journal › Journal article › Commissioned › peer-review
- Published
Structural Conservation Despite Huge Sequence Diversity Allows EPCR Binding by the PfEMP1 Family Implicated in Severe Childhood Malaria
Lau, C. K. Y., Turner, Louise, Jespersen, Jakob Schmidt, Lowe, E. D., Petersen, Bent, Wang, Christian William, Petersen, J. E. V., Lusingu, J., Theander, Thor Grundtvig, Lavstsen, Thomas & Higgins, M. K., 14 Jan 2015, In: Cell Host & Microbe. 17, 1, p. 118-29 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasmodium falciparum-infected erythrocyte knob density is linked to the PfEMP1 variant expressed
Subramani, R., Quadt, K., Jeppesen, A. E., Hempel, C., Petersen, J. E. V., Hassenkam, Tue, Hviid, Lars & Barfod, Lea Klingenberg, 2015, In: mBio. 6, 5, 7 p., e01456-15.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania
Hansson, Helle Smedegaard, Turner, Louise, Møller, L., Wang, Christian William, Minja, D., Gesase, S., Mmbando, B., Bygbjerg, Ib Christian, Theander, Thor Grundtvig, Lusingu, J. P. A., Alifrangis, Michael & Lavstsen, Thomas, 2015, In: Malaria Journal. 14, 9 p., 474.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multiple Plasmodium falciparum erythrocyte membrane protein 1 variants per genome can bind IgM via its Fc fragment Fcμ
Jeppesen, A., Ditlev, S. B., Soroka, V., Stevenson, E. K., Turner, Louise, Dzikowski, R., Hviid, Lars & Barfod, Lea Klingenberg, 2015, In: Infection and Immunity. 83, 10, p. 3972-81 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families
Sander, Adam F. , Lavstsen, Thomas, Rask, T. S., Lisby, Michael, Salanti, Ali, Fordyce, S. L., Jespersen, Jakob Schmidt, Carter, R., Deitsch, K. W., Theander, Thor Grundtvig, Pedersen, A. G. & Arnot, D. E., 2014, In: Nucleic Acids Research. 42, 4, p. 2270-81 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differences in gene transcriptomic pattern of Plasmodium falciparum in children with cerebral malaria and asymptomatic carriers
Almelli, T., Nuel, G., Bischoff, E., Aubouy, A., Elati, M., Wang, Christian William, Dillies, M., Coppée, J., Ayissi, G. N., Basco, L. K., Rogier, C., Ndam, N. T., Deloron, P. & Tahar, R., 2014, In: PloS one. 9, 12, p. e114401Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria
Zhang, Q., Siegel, T. N., Martins, R. M., Wang, F., Cao, J., Gao, Q., Cheng, X., Jiang, L., Hon, C., Scheidig-Benatar, C., Sakamoto, H., Turner, Louise, Jensen, Anja Ramstedt, Claes, A., Guizetti, J., Malmquist, N. A. & Scherf, A., 2014, In: Nature. 531, p. 431-435Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modeling malaria infection and immunity against variant surface antigens in Príncipe island, West Africa
Bandeiras, C., Trovoada, M. J., Gonçalves, L. A., Marinho, C. R. F., Turner, Louise, Hviid, Lars, Penha-Gonçalves, C. & Gomes, M. G. M., 2014, In: PloS one. 9, 2, p. e88110Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Malaria's deadly grip: cytoadhesion of Plasmodium falciparum-infected erythrocytes
Smith, J. D., Rowe, J. A., Higgins, M. K. & Lavstsen, Thomas, Dec 2013, In: Cellular Microbiology Online. 15, 12, p. 1976-83 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early gametocytes of the malaria parasite Plasmodium falciparum specifically remodel the adhesive properties of infected erythrocyte surface
Tibúrcio, M., Silvestrini, F., Bertuccini, L., Sander, Adam F. , Turner, Louise, Lavstsen, Thomas & Alano, P., 1 Nov 2013, In: Cellular Microbiology Online. 15, 4, p. 647-659Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum
Jiang, L., Mu, J., Zhang, Q., Ni, T., Srinivasan, P., Rayavara, K., Yang, W., Turner, L., Lavstsen, T., Theander, T. G., Peng, W., Wei, G., Jing, Q., Wakabayashi, Y., Bansal, A., Luo, Y., Ribeiro, J. M. C., Scherf, A., Aravind, L., Zhu, J. & 2 others, , 11 Jul 2013, In: Nature. 499, 7457, p. 223-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Severe malaria is associated with parasite binding to endothelial protein C receptor
Turner, Louise, Lavstsen, Thomas, Berger, S. S., Wang, Christian William, Petersen, J. E. V., Avril, M., Brazier, A. J., Freeth, J., Jespersen, Jakob Schmidt, Nielsen, Morten Agertoug, Magistrado, P., Lusingu, J., Smith, J. D., Higgins, M. K. & Theander, Thor Grundtvig, 27 Jun 2013, In: Nature. 498, 7455, p. 502-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular architecture of a complex between an adhesion protein from the malaria parasite and intracellular adhesion molecule 1
Brown, A., Turner, Louise, Christoffersen, S., Andrews, K. A., Szestak, T., Zhao, Y., Larsen, Sine, Craig, A. G. & Higgins, M. K., 22 Feb 2013, In: Journal of Biological Chemistry. 288, 8, p. 5992-6003 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Novel Domain Cassette Identifies Plasmodium falciparum PfEMP1 Proteins Binding ICAM-1 and Is a Target of Cross-Reactive, Adhesion-Inhibitory Antibodies
Bengtsson, A., Joergensen, L., Rask, T. S., Olsen, R. W., Andersen, M. A., Turner, Louise, Theander, Thor Grundtvig, Hviid, Lars, Higgins, M. K., Craig, A., Brown, A. & Jensen, Anja Ramstedt, 2013, In: Journal of Immunology. 190, 1, p. 240-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of the domain cassette 8 Plasmodium falciparum erythrocyte membrane protein 1 is associated with cerebral malaria in Benin
Bertin, G. I., Lavstsen, Thomas, Guillonneau, F., Doritchamou, J., Wang, Christian William, Jespersen, Jakob Schmidt, Ezimegnon, S., Fievet, N., Alao, M. J., Lalya, F., Massougbodji, A., Ndam, N. T., Theander, Thor Grundtvig & Deloron, P., 2013, In: P L o S One. 8, 7, p. e68368Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasmodium falciparum Expressing Domain Cassette 5 Type PfEMP1 (DC5-PfEMP1) Bind PECAM1
Berger, S. S., Turner, Louise, Wang, Christian William, Petersen, J. E. V., Kraft, M., Lusingu, J. P. A., Mmbando, B., Marquard, A. M., Bengtsson, D. B. A. C., Hviid, Lars, Nielsen, Morten Agertoug, Theander, Thor Grundtvig & Lavstsen, Thomas, 2013, In: PloS one. 8, 7, p. e69117Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children
Lavstsen, Thomas, Turner, Louise, Saguti, F., Magistrado, P. A., Rask, T. S., Jespersen, Jakob Schmidt, Wang, Christian William, Berger, S. S., Baraka, V., Marquard, A. M., Seguin-Orlando, A., Willerslev, Eske, Gilbert, M Thomas P, Lusingu, J. P. A. & Theander, Thor Grundtvig, 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 26, p. E1791-E1800 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells
Claessens, A., Adams, Y., Ghumra, A., Lindergard, G., Buchan, C. C., Andisi, C., Bull, P. C., Mok, S., Gupta, A. P., Wang, Christian William, Turner, Louise, Arman, M., Raza, A., Bozdech, Z. & Rowe, J. A., 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 26, p. E1772-81Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence for in vitro and in vivo expression of the conserved VAR3 (type 3) plasmodium falciparum erythrocyte membrane protein 1
Wang, Christian William, Lavstsen, Thomas, Bengtsson, D. C., Magistrado, P. A., Berger, S. S., Marquard, A. M., Alifrangis, Michael, Lusingu, J. P., Theander, Thor Grundtvig & Turner, Louise, 2012, In: Malaria Journal. 11, 1, p. 129Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of a type B RIFIN in Plasmodium falciparum merozoites and gametes
Mwakalinga, S. B., Wang, Christian William, Bengtsson, D. C., Turner, Louise, Dinko, B., Lusingu, J. P., Arnot, D. E., Sutherland, C. J., Theander, Thor Grundtvig & Lavstsen, Thomas, 2012, In: Malaria Journal. 11, 1, p. 429Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites
Bejon, P., Turner, Louise, Lavstsen, Thomas, Cham, G., Olotu, A., Drakeley, C. J., Lievens, M., Vekemans, J., Savarese, B., Lusingu, J., von Seidlein, L., Bull, P. C., Marsh, K. & Theander, Thor Grundtvig, 1 Jan 2011, In: P L o S One. 6, 6, p. e21711Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibodies against PfEMP1, RIFIN, MSP3 and GLURP are acquired during controlled Plasmodium falciparum malaria infections in naïve volunteers
Turner, Louise, Wang, Christian William, Lavstsen, Thomas, Mwakalinga, S. B., Sauerwein, R. W., Hermsen, C. C. & Theander, Thor Grundtvig, 2011, In: P L o S One. 6, 12, p. e29025Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Positive selection of Plasmodium falciparum parasites with multiple var2csa-type PfEMP1 genes during the course of infection in pregnant women
Sander, A. F., Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Leke, R. G. F., Lo, Y. Y., Bobbili, N., Arnot, D. E. & Taylor, D. W., 2011, In: Journal of Infectious Diseases. 203, 11, p. 1679-85 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes - divide and conquer
Rask, T. S., Hansen, D. A., Theander, Thor Grundtvig, Gorm Pedersen, A. & Lavstsen, Thomas, 2010, In: P L o S Computational Biology. 6, 9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian children
Cham, G. K. K., Turner, Louise, Kurtis, J. D., Mutabingwa, T., Fried, M., Jensen, Anja Ramstedt, Lavstsen, Thomas, Hviid, Lars, Duffy, P. E. & Theander, Thor Grundtvig, 2010, In: Infection and Immunity. 78, 11, p. 4653-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of a major rif transcript common to gametocytes and sporozoites of Plasmodium falciparum
Wang, Christian William, Mwakalinga, S. B., Sutherland, C. J., Schwank, S., Sharp, S., Hermsen, C. C., Sauerwein, R. W., Theander, Thor Grundtvig & Lavstsen, Thomas, 2010, In: Malaria Journal. 9, 1, p. 147Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Macrogeographical variability in the great call of Hylobates agilis: assessing the applicability of vocal analysis in studies of fine-scale taxonomy of gibbons
Heller, Rasmus, Sander, Adam F. , Wang, Christian William, Usman, F. & Dabelsteen, Torben, 2010, In: American Journal of Primatology. 72, 2, p. 142-51 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Surface co-expression of two different PfEMP1 antigens on single Plasmodium falciparum-infected erythrocytes facilitates binding to ICAM1 and PECAM1
Joergensen, L., Bengtsson, D. C., Bengtsson, A., Ronander, E., Berger, S. S., Turner, Louise, Dalgaard, M. B., Cham, G. K. K., Victor, M. E., Lavstsen, Thomas, Theander, Thor Grundtvig, Arnot, D. E. & Jensen, Anja Ramstedt, 2010, In: PLoS Pathogens. 6, 9, p. e1001083Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
An upstream open reading frame controls translation of var2csa, a gene implicated in placental malaria
Amulic, B., Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten Agertoug & Deitsch, K. W., 2009, In: PLoS Pathogens. 5, 1, p. e1000256Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chondroitin sulphate A (CSA)-binding of single recombinant Duffy-binding-like domains is not restricted to Plasmodium falciparum Erythrocyte Membrane Protein 1 expressed by CSA-binding parasites
Resende, M., Ditlev, S. B., Nielsen, Morten Agertoug, Bodevin, S., Bruun, S., Pinto, V. V., Clausen, Henrik, Turner, Louise, Theander, Thor Grundtvig, Salanti, Ali & Dahlbäck, M., 2009, In: International Journal for Parasitology. 39, 11, p. 1195-204 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human monoclonal IgG selection of Plasmodium falciparum for the expression of placental malaria-specific variant surface antigens
Soerli, J., Barfod, Lea Klingenberg, Lavstsen, Thomas, Bernasconi, N. L., Lanzavecchia, A. & Hviid, Lars, 2009, In: Parasite Immunology. 31, 6, p. 341-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multiple var2csa-type PfEMP1 genes located at different chromosomal loci occur in many Plasmodium falciparum isolates
Sander, Adam F. , Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten Agertoug, Magistrado, P., Lusingu, J., Ndam, N. T. & Arnot, D. E., 2009, In: PLoS ONE. 4, 8, p. e6667Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preferential transcription of conserved rif genes in two phenotypically distinct Plasmodium falciparum parasite lines
Wang, Christian William, Magistrado, P. A., Nielsen, Morten Agertoug, Theander, Thor Grundtvig & Lavstsen, Thomas, 2009, In: International Journal for Parasitology. 39, 6, p. 655-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sequential, ordered acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 domains
Cham, G. K. K., Turner, Louise, Lusingu, J., Vestergaard, L., Mmbando, B. P., Kurtis, J. D., Jensen, Anja Ramstedt, Salanti, Ali, Lavstsen, Thomas & Theander, Thor Grundtvig, 2009, In: Journal of Immunology. 183, 5, p. 3356-63 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Plasmodium falciparum var gene transcription strategy at the onset of blood stage infection in a human volunteer
Wang, Christian William, Hermsen, C. C., Sauerwein, R. W., Arnot, D. E., Theander, Thor Grundtvig & Lavstsen, Thomas, 2009, In: Parasitology International. 58, 4, p. 478-80 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Plasmodium falciparum transcriptome analysis reveals pregnancy malaria associated gene expression
Tuikue Ndam, N., Bischoff, E., Proux, C., Lavstsen, Thomas, Salanti, Ali, Guitard, J., Nielsen, Morten Agertoug, Coppée, J., Gaye, A., Theander, Thor Grundtvig, David, P. H. & Deloron, P., 2008, In: PLoS ONE. 3, 3, p. e1855Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A method for visualizing surface-exposed and internal PfEMP1 adhesion antigens in Plasmodium falciparum infected erythrocytes
Bengtsson, D., Sowa, K. M., Salanti, Ali, Jensen, Anja Ramstedt, Joergensen, L., Turner, Louise, Theander, Thor Grundtvig & Arnot, D. E., 2008, In: Malaria Journal. 7, p. 101Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A semi-automated multiplex high-throughput assay for measuring IgG antibodies against Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) domains in small volumes of plasma
Cham, G. K. K., Kurtis, J., Lusingu, J., Theander, Thor Grundtvig, Jensen, Anja Ramstedt & Turner, Louise, 2008, In: Malaria Journal. 7, p. 108Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
3D7-derived Plasmodium falciparum erythrocyte membrane protein 1 is a frequent target of naturally acquired antibodies recognizing protein domains in a particular pattern independent of malaria transmission intensity
Joergensen, L., Vestergaard, L. S., Turner, Louise, Magistrado, P., Lusingu, J. P., Lemnge, M., Theander, Thor Grundtvig & Jensen, Anja Ramstedt, 2007, In: Journal of Immunology. 178, 1, p. 428-35 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multiple Plasmodium falciparum erythrocyte membrane protein 1 variants per genome can bind IgM via its Fc fragment Fcμ
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Modeling malaria infection and immunity against variant surface antigens in Príncipe island, West Africa
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Plasmodium falciparum-infected erythrocyte knob density is linked to the PfEMP1 variant expressed
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